Clinical Trials on Refractory Epilepsy in Australia

Total 260 results

Cerebral Therapeutics LLC

Terminated

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

Refractory Epilepsy

Israel, Australia
MedtronicNeuro

Completed

Product Surveillance Registry- Deep Brain Stimulation for Epilepsy (MORE)

Refractory Epilepsy

Belgium, Sweden, Austria, United Kingdom, Poland, Germany, Portugal, Canada, Finland, Hungary, Italy, Netherlands, Russian Federation
Sándor Beniczky
Hospital del Mar; Centro Hospitalar e Universitário de Coimbra, E.P.E.; Motol... and other collaborators

Active, not recruiting

Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation (PROMAESIS)

Surgery | Refractory Epilepsy | Electroencephalography | Brain Imaging

Spain, Portugal, Austria, Czechia, Denmark, Germany, Italy, Romania
Genovate-NaviFUS (Australia) Pty Ltd.
Genovate Biotechnology Co., Ltd.,; NaviFUS Corporation

Recruiting

Evaluation of the NaviFUS System in Drug Resistant Epilepsy

Drug Resistant Epilepsy | Epilepsy, Temporal Lobe

Australia
Supernus Pharmaceuticals, Inc.
Melbourne Health

Completed

Bioavailability, Safety, and Tolerability of BIS-001 ER

Epilepsy, Complex Partial

Australia
CStone Pharmaceuticals
Bayer

Completed

A Study of CS1001 in Combination With Regorafenib in Patients With Advanced or Refractory Solid Tumors

Advanced Refractory Solid Tumors

Australia
ES Therapeutics Australia Pty Ltd

Recruiting

Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients With Drug Resistant Epilepsy

Drug Resistant Epilepsy

Australia
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Dravet Syndrome

Australia
Curon Biopharmaceutical (Australia) Co Pty Ltd
Novotech (Australia) Pty Limited

Terminated

A Study of CN1 in Combination With CN401 in Adult Patients With Relapsed/Refractory Lymphoid Malignancies

Relapsed Lymphoid Malignancies | Refractory Lymphoid Malignancies

Australia
Duke University
Christian Doppler University Hospital

Enrolling by invitation

5-SENSE Score Validation Study

Epilepsy Intractable

United States, Spain, Australia, Austria, Canada, Czechia, Denmark, France, Germany, Japan, Romania, Switzerland
St Vincent's Hospital Melbourne
University of Melbourne; Seer Medical

Completed

Validation of a Seizure Monitoring System

Epilepsy

Australia
Seer Medical Pty Ltd

Enrolling by invitation

Development of a Minimally Invasive Seizure Gauge

Epilepsy

Australia
Xenon Pharmaceuticals Inc.

Terminated

An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE (EPIK-OLE)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Epilepsy | Epileptic Syndromes | Disease | Epilepsy; Seizure | Epilepsy in Children

United States, Australia, Belgium
Cerebral Therapeutics LLC

Terminated

Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion

Focal Epilepsy

Israel, Australia
Supernus Pharmaceuticals, Inc.

Recruiting

Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy

Epilepsy | Seizures, Epileptic

Australia
St Vincent's Hospital Melbourne
University of Melbourne

Completed

A Deep Brain Stimulation System in Epilepsy: Tracking Neural Excitability

Epilepsy | Nodular Heterotopia

Australia
Abbott Medical Devices

Completed

HeartMate 3 CE Mark Study Long Term Follow-up (HM3 CE LTFU)

Advanced Refractory Left Ventricular Heart Failure

Germany, Canada, Austria, Czechia, Kazakhstan, Australia
NYU Langone Health

Recruiting

Human Epilepsy Project 3 (HEP3)

Idiopathic Generalized Epilepsy

United States, Australia
University of Minnesota

Not yet recruiting

Microelectrode Recordings From the Vagus Nerve in Awake Humans

Epilepsy

United States, Australia
NeuroVista Corporation

Terminated

Seizure Advisory System Feasibility Study

Epilepsy

Australia
Cerebral Therapeutics LLC
Neuroscience Trials Australia

Completed

A Dose Ranging Pilot Study for Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Temporal Seizures

Epilepsy

Australia
Spago Nanomedical AB

Recruiting

A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer (Tumorad)

Solid Tumor | Metastatic Cancer | Refractory Cancer | Locally Advanced Solid Tumor | Unresectable Solid Tumor | Recurrent Solid Tumor

Australia
Medical University of Vienna
Roche Pharma AG; Allcyte GmbH

Recruiting

Comprehensive Genomic Profiling and Next Generation Functional Drug Screening for Patients With Aggressive Haematological Malignancies (EXALT-2)

Refractory Acute Myeloid Leukemia | Advanced Lymphoma | Refractory Lymphoma | Refractory Leukemia | Refractory T-Cell Lymphoma

Austria
Karl Landsteiner Institute for Clinical Epilepsy...
AIT Austrian Institute of Technology GmbH; Brainhero GmbH

Recruiting

DigitalEPI - A Prospective Pilot Study

Epilepsy

Austria
Abbott Medical Devices
Thoratec Corporation; KCRI; Center for Life Sciences; Emergo

Completed

HeartMate 3™ CE Mark Clinical Investigation Plan (HM3 CE Mark)

Advanced Refractory Left Ventricular Heart Failure

Germany, Australia, Austria, Canada, Czechia, Kazakhstan
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy (EXPAND)

Childhood Absence Epilepsy | Juvenile Absence Epilepsy

United States, Australia, Georgia, Italy, Poland, Romania, Slovakia, Spain, Ukraine, Belgium
Binacea Pharma, Inc.

Recruiting

Safety and Preliminary Efficacy of BNA035 in Patients With Advanced Solid Tumors

Refractory Solid Tumors

Australia
Cerecin

Active, not recruiting

Tricaprilin Infantile Spasms Pilot Study

Infantile Spasm

Singapore, Australia
UCB Pharma

Terminated

Hormonal and Lipid Levels in Male Subjects After a Switch From Carbamazepine to Lacosamide (VICTOR)

Epilepsy, Partial

Austria, Germany, Spain
ElectroCore INC

Terminated

Neurostimulation to the Vagus Nerve for the Reduction in Frequency of Seizures Associated With Epilepsy

Seizure

Australia
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Study of HSK29116 in Adults With Relapsed/Refractory B-cell Malignancies

Relapsed/Refractory B-Cell Malignancies

China, Australia
Great Ormond Street Hospital for Children NHS Foundation...
The Hospital for Sick Children; Boston Children's Hospital; Murdoch Childrens...

Recruiting

Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services (Gene-STEPS)

Epilepsy

United States, Canada, Australia, United Kingdom
Xenon Pharmaceuticals Inc.

Terminated

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Epilepsy | Epileptic Syndromes | Disease | Epilepsy; Seizure | Epilepsy in Children

United States, Spain, Australia, Belgium, Italy
Australasian Leukaemia and Lymphoma Group

Recruiting

A Phase 2 Trial of GlOfitamab anD pIrtobrutinib in Mantle Cell Lymphoma Patients With Prior BTK Inhibitor Exposure. (GOlDiLOX)

Mantle Cell Lymphoma | Mantle Cell Lymphoma Refractory

Australia
LivaNova

Active, not recruiting

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. (CORE-VNS)

Epilepsy | Seizures | Drug Resistant Epilepsy

Australia, Italy, United States, Israel, United Kingdom, Canada, Brazil, Japan, Belgium, India, Austria, China, Netherlands, Poland, Portugal, Saudi Arabia
Eisai Limited

Completed

Comparing The Effect On Cognition Of Adjunctive Therapy With Zonisamide Versus Sodium Valproate

Epilepsy

Finland, Austria
NYU Langone Health
The Epilepsy Study Consortium

Completed

The Human Epilepsy Project (HEP)

Focal Epilepsy

United States, Canada, Australia
Sydney Children's Hospitals Network
German Cancer Research Center; Australian & New Zealand Children's Haematology... and other collaborators

Active, not recruiting

PRecISion Medicine for Children With Cancer (PRISM)

Childhood Cancer | Relapsed Cancer | Refractory Cancer | Childhood Leukemia | Childhood Solid Tumor | Childhood Brain Tumor

Australia
Onconova Therapeutics, Inc.

Completed

Efficacy and Safety of IV Rigosertib in MDS Patients With Excess Blasts Progressing After Azacitidine or Decitabine

Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia | Cytopenia | Refractory Anemia With Excess Blasts

United States, Australia, Spain, Italy, Germany, France, Sweden, Denmark
Peter MacCallum Cancer Centre, Australia

Recruiting

Genetically Risk-Stratified Venetoclax, Ibrutinib, Rituximab (± Navitoclax) in Relapsed/Refractory Mantle Cell Lymphoma

Mantle Cell Lymphoma Refractory

Australia
Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
BeiGene

Recruiting

A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies

Refractory Chronic Lymphocytic Leukemia | Refractory Non-Hodgkin Lymphoma | Relapsed Follicular Lymphoma | Refractory Small Lymphocytic Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Refractory Diffuse Large B-cell Lymphoma | Transformed Non-Hodgkin Lymphoma | Relapsed... and other conditions

China, Australia
SK Life Science, Inc.

Recruiting

Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures

Primary Generalized Epilepsy

United States, Spain, Germany, Hungary, Korea, Republic of, Australia, Bulgaria, Czechia, Poland, Slovakia, Ukraine
UCB Pharma GmbH

Completed

Study Evaluating Changes in Total Drug Load and Seizure Frequency Using Vimpat® (Lacosamide) in Combination Therapy (VICTOS)

Focal Epilepsy With and Without Secondary Generalization

Germany, Austria
IGM Biosciences, Inc.

No longer available

Expanded Access of Imvotamab (IGM-2323) in Patients With R/R NHL

Relapsed/Refractory Non-Hodgkin Lymphomas

Australia, Korea, Republic of, Spain
Eisai Limited

Terminated

Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures Associated With Idiopathic Generalised Epilepsy

Epilepsy

Australia, Serbia, Germany, Czech Republic, Romania, Estonia, Lithuania, Croatia, Finland, Hungary, Poland, Russian Federation, Ukraine
Brain Sentinel

Unknown

An Exploratory Trial Using sEMG to Differentiate PNES From Epileptic Seizures

Epilepsy | Non-Epileptic Seizure | Motor Seizure

Austria
Encoded Therapeutics

Terminated

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies (ENVISION)

Dravet Syndrome

United States, Spain, Australia, United Kingdom
Australian & New Zealand Children's Haematology...
Medical Research Future Fund; Minderoo Foundation; Children's Cancer Institute...

Recruiting

Precision Medicine for Every Child With Cancer (ZERO2)

Childhood Cancer | Relapsed Cancer | Refractory Cancer | Childhood Leukemia | Childhood Solid Tumor | Childhood Brain Tumor

Australia
Eisai Inc.

Completed

A Double-blind Study to Compare the Efficacy and Safety of Zonisamide and Carbamazepine as Monotherapy, in Newly Diagnosed Partial Epilepsy

Epilepsy

Australia, France, Poland, Germany, Spain, India, Serbia, Greece, Korea, Republic of, Russian Federation, Taiwan, Hungary, Italy, Sweden, Denmark, Slovakia, United Kingdom, South Africa

Clinical Trials on Refractory Epilepsy in Australia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gambia

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Rare Diseases

Drug Interventions

Dietary Supplements

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