Clinical Trials on Refractory Neoplasms in Germany

Total 6296 results

Stichting Hemato-Oncologie voor Volwassenen Nederland
Deutsch-Österreichische Studiengruppe Akute Myeloische Leukämie (AMLSG)

Recruiting

A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy (HOVON150AML)

Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts-2

Australia, Austria, Belgium, Estonia, Finland, France, Germany, Ireland, Lithuania, Luxembourg, Netherlands, Norway, Spain, Sweden, Switzerland
Stichting Hemato-Oncologie voor Volwassenen Nederland
Astellas Pharma Global Development, Inc.; Deutsch-Österreichische Studiengruppe...

Active, not recruiting

A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy (HOVON 156 AML)

Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts-2

Netherlands, Belgium, Germany, Switzerland, Australia, Finland, Norway, Sweden, Austria, France, Ireland, Lithuania, Luxembourg, Spain
AIO-Studien-gGmbH
Sanofi; Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt

Completed

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Rectal Cancer | Rectosigmoid Cancer

Germany
University of Leipzig
German Federal Ministry of Education and Research

Completed

Identification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Gastric Cancer (VARIANZ)

Stomach Neoplasms | Esophageal Neoplasms

Germany
University Hospital, Essen

Recruiting

Adaptive Radiotherapy in Patients With Gynecological Tumors (ProART)

Cervical Carcinoma | Radiation | Adaptive Radiotherapy | Image Guided Radiotherapy | Gynecological Tumor | Optimization | Curative Treatment | Adaptive Radiation Therapy

Germany
Amgen

Active, not recruiting

A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC) (DeLLphi-301)

Relapsed/Refractory Small Cell Lung Cancer

United States, Belgium, Italy, Spain, Portugal, Austria, Greece, Korea, Republic of, Denmark, Netherlands, Germany, France, Taiwan, Japan, United Kingdom, Poland, Switzerland, Singapore
Novartis Pharmaceuticals

Completed

Efficacy of Octreotide Treatment in Patients With Primary Inoperable Thymoma

Thymoma

Germany
University of Regensburg

Completed

Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma

Pineoblastoma

Germany
Smart Medical Systems Ltd.
Fujifilm

Recruiting

Comparing Detection of Standard Colonoscopy, CAD-EYE and Combined CAD-EYE and G-EYE® Aided Colonoscopy

Colorectal Cancer | Adenoma

Germany
Johannes Gutenberg University Mainz

Completed

Intraoperative Monitoring of the Pelvic Autonomic Nerves (NEUROS)

Rectal Cancer

Germany
Theraclion

Completed

Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU) (HIFU)

Breast Fibroadenoma

Germany
Universitätsmedizin Mannheim
Heidelberg University

Terminated

Elimination of Peritoneal Tumor Cells With Extensive Peritoneal Lavage During Surgery in Patients With Gastric Cancer (EIPL)

Adenocarcinoma | Stomach Neoplasms

Germany
Amgen

Terminated

A Study to Assess AMG 701 Montherapy, or in Combination With Pomalidomide, With or Without, Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States, Australia, Japan, Germany, Netherlands, Canada
MedInnovation GmbH
Helios Klinikum Berlin-Buch

Terminated

Validation of MMS Test for Cancer Monitoring (MMS-TM)

Melanoma | Sarcoma | Stomach Cancer | Colo-rectal Cancer

Germany
Zydolab - Institute of Cytology and Immune Cytochemistry

Completed

Lugol's Solution in Addition to Acetic Acid During Colposcopy

Uterine Cervical Dysplasia

Germany
Photocure

Completed

A Dose-finding Study of MAL and HAL Photodynamic Therapy of Cervical Premalignant Lesions.

Cervical Dysplasia

Germany, Norway
University Hospital Heidelberg

Active, not recruiting

Carbon Ion Radiotherapy for Atypical Meningiomas (MARCIE)

Meningioma

Germany
University Hospital Heidelberg

Recruiting

Plasma Extracellular Vesicles in Meningioma Patients (MOLI)

Meningioma

Germany
Zydolab - Institute of Cytology and Immune Cytochemistry

Completed

Hemostatic Procedure After Biopsy of the Cervix

Uterine Cervical Dysplasia

Germany
Ludwig-Maximilians - University of Munich

Recruiting

Protective VEGF Inhibition for Isotoxic Dose Escalation in Glioblastoma (PRIDE)

Glioblastoma

Germany
Aesculap AG

Completed

CAIman 5 Articulating Maryland in coloRECTAL Cancer Surgery (CAIRECTAL)

Colorectal Cancer

Germany
Technical University of Munich
German Cancer Aid

Completed

Tertiary Prevention by Exercise in Colorectal Cancer Therapy (F-PROTECT)

Colorectal Cancer

Germany
CONKO-Studiengruppe
Eli Lilly and Company; medac GmbH

Completed

Chemotherapeutic Trial With Gemcitabine, Cisplatin, 5-FU and Folinic Acid in Esophageal Cancer (CONKO-101)

Esophageal Cancer

Germany
Heidelberg University

Completed

Ion Prostate Irradiation (IPI)

Prostatic Neoplasms

Germany
University of Ulm
Brainlab AG

Recruiting

Evaluation of 3D Ultrasound in Brain Tumor Surgery (Neuro3DUS)

Residual Tumor

Germany
Prof. Wolfgang Janni

Completed

DETECT III - A Multicenter, Phase III Study to Compare Standard Therapy +/- Lapatinib in HER2-ve MBC-Patients With HER2+ve CTCs (DETECT III)

HER2-negative Metastatic Breast Cancer | HER2-positive Circulating Tumor Cells

Germany
University Hospital Tuebingen

Completed

Preoperative Percutaneous Radiofrequency Ablation of Primary and Secondary Lung Tumors

Lung Cancer | Lung Metastasis

Germany
University Hospital Heidelberg

Recruiting

Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma (INDIGO)

Low Grade Glioma

Germany
Prof. Dr. Juergen Wolf
Charite University, Berlin, Germany; University Hospital, Essen; Goethe University and other collaborators

Recruiting

National Network Genomic Medicine Lung Cancer, Germany (nNGM)

Carcinoma, Non-Small-Cell Lung

Germany
Goethe University

Active, not recruiting

Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients (ACO/ARO/AIO-21)

Rectal Cancer

Germany
Norgine

Completed

Pharmacodynamic and Clinical Evaluation of Dose and Taste-optimised Low Volume PEG-based Bowel Cleansing Solutions Using the Split-dosing Intake Regimen in Healthy Subjects and in Subjects Undergoing Screening Colonoscopy

Colon Cancer

Germany
Norgine

Completed

Study to Assess the Tolerability, Safety and Efficacy of an Adapted Gut Cleansing Solution in Routine Colon Cleansing Prior to Colonoscopies

Colon Cancer

Germany
Heidelberg University

Terminated

Pilot Study for Evaluation of the Need for Protective Ileostomy After Low Anterior Resection Due to Rectal Cancer

Rectal Cancer

Germany
Charite University, Berlin, Germany

Completed

Fasting and Nutritional Therapy in Patients With Advanced Metastatic Prostate Cancer

Prostatic Neoplasms | Fasting

Germany
Heidelberg University

Completed

Combination Therapy of Gemcitabine and Trabectedin in L-sarcomas

Leiomyosarcoma | Liposarcoma

Germany
University Hospital Heidelberg

Withdrawn

Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial. (PINOCCHIO)

Skull Base Meningioma

Germany
Johannes Gutenberg University Mainz
Interdisciplinary Center Clinical Trials (IZKS), University Medical Center...

Recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy of Cabozantinib in Patients With Hepatocellular Carcinoma and Impaired Liver Function (CaboCHILD)

Hepatocellular Carcinoma

Germany
Hofmann, Bernd, M.D.

Completed

1.5T Intraoperative MR Imaging in Craniopharyngiomas

Craniopharyngioma

Germany
Krankenhaus Nordwest

Completed

Oxaliplatin and 5-Fluorouracil With or Without Docetaxel in Elderly Patients (>65 y) With Stomach and Esophagus Cancer

Gastric Cancer | Adenocarcinoma of the Esophagogastric Junction

Germany
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Combination With Carboplatin/Paclitaxel in First Line in Patients With Advanced Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (OTILIA)

Peritoneal Neoplasms

Germany
AIO-Studien-gGmbH
Roche Pharma AG

Completed

Explorative Phase II Study of Perioperative Treatment in Patients With Adenocarcinoma of the Gastroesophageal Junction or Stomach (HerFLOT)

Adenocarcinoma of the Gastroesophageal Junction | Adenocarcinoma of the Stomach

Germany
University of Ulm

Completed

Concentration of Ertapenem in Colorectal Tissue

Rectal Neoplasms | Colonic Neoplasms | Diverticulosis, Colonic

Germany
University of Erlangen-Nürnberg Medical School

Recruiting

Focal Brachytherapy in Patients With Selected "Low-risk" Prostate Cancer - a Phase-II-trial (FOKAL-BT)

Prostate Cancer

Germany
Hoffmann-La Roche

Completed

An Observational Study of Herceptin (Trastuzumab) in Patients With HER2-positive Advanced Gastric Cancer

Gastric Cancer

Germany
Hoffmann-La Roche

Completed

Non-Interventional Study of Xeloda (Capecitabine) in Patients With Gastric Cancer

Gastric Cancer

Germany
University of Erlangen-Nürnberg Medical School

Unknown

Socioeconomic Aspects Before and After Radiation Therapy in Patient With Prostate Cancer (ECOPRO)

Prostate Cancer

Germany
Shanghai Zhongshan Hospital
Evangelisches Krankenhaus Düsseldorf

Completed

Water-jet Assisted ESD vs Conventional ESD Technique for Treating Early Gastric Cancer

Stomach Neoplasms

Germany
Ludwig-Maximilians - University of Munich
Sanofi

Unknown

Multicenter Study to Perioperative Chemotherapy for Resectable Adenocarcinoma in Gastric Cancer

Gastric Cancer

Germany
Johannes Gutenberg University Mainz

Completed

Efficacy of Irinotecan and Capecitabine Versus(vs) Cisplatin and Capecitabine in Patients With Esophago-Gastric Cancer

Gastric Cancer

Germany
Charite University, Berlin, Germany

Completed

Multiparametric Characterization of Orbital Tumors by MRI

Orbital Tumors

Germany

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