Clinical Trials on Refractory Hematologic Cancer

Total 67850 results

Immatics Biotechnologies GmbH
Bristol-Myers Squibb

Recruiting

IMA401 TCER® in Recurrent and/or Refractory Solid Tumors

Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer

Germany
Henry Ford Health System

Recruiting

HLA-Haploidentical Peripheral Blood Stem Cell Transplantation With Post-transplant Cyclophosphamide and Bortezomib

Hematological Malignancy

United States
Sanofi

Completed

Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies

Hematological Malignancy

Greece, Spain, Peru, Israel, United States, Argentina, Belgium, Brazil, Chile, Finland, France, Italy, Mexico, Russian Federation, Turkey, Ukraine, United Kingdom
University of Copenhagen
Zealand University Hospital

Enrolling by invitation

Individual Dietary Counseling Based on Taste-tests in Patients With Hematological Cancer in Cytostatic Therapy (HCP)

Hematological Malignancy

Denmark
Washington University School of Medicine
Barnes-Jewish Hospital

Terminated

Body Scan Activity on Bone Marrow Transplant Patients and Their Caregivers

Hematological Malignancy

United States
Institut Paoli-Calmettes

Completed

Phase I of Infusion of Selected Donor NK Cells After Allogeneic Stem Cell Transplantation (DLI-NK)

Hematological Malignancy

France
Sidney Kimmel Cancer Center at Thomas Jefferson...

Active, not recruiting

Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Plasma Cell Myeloma | Aplastic Anemia | Malignant Neoplasm | Myeloproliferative Neoplasm | Indolent Non-Hodgkin Lymphoma | Acute Myeloid Leukemia in Remission | Refractory Anemia | Refractory Anemia With... and other conditions

United States
Skyline Diagnostics BV
Illumina, Inc.

Terminated

Accuracy Testing of the Chromosomal Aberration and Gene Mutation Markers of the AMLProfiler

Acute Myeloid Leukemia (AML) | Acute Promyelocytic Leukemia (APL) | Refractory Anemia With Excess of Blasts (RAEB)

United States, Germany, Netherlands, United Kingdom
Peking University People's Hospital
Sanofi

Recruiting

The Optimization of Haploidentical Hematopoietic Stem Cell Transplantation

Hematological Malignancy

China
M.D. Anderson Cancer Center

Recruiting

Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances

Hematological Malignancy

United States
Beckman Coulter, Inc.

Completed

DxFLEX 10C Clinical Study

Hematological Malignancy

United States, Canada, Germany
Fate Therapeutics

Terminated

Long-term Follow-Up Study Following Treatment With Fate Therapeutics' Engineered Cellular Immunotherapy

Hematological Malignancy

United States
University Hospital, Strasbourg, France

Unknown

MS Detection of Somatic Mutations in Hematological Malignancies (MAHM)

Hematological Malignancy

France
Universitaire Ziekenhuizen KU Leuven
Institutul Clinic Fundeni

Completed

A New Dosing Regimen for Posaconazole Prophylaxis in Children Based on Body Surface Area

Hematological Malignancy

Belgium, Romania
Assiut University

Not yet recruiting

Anemia in Systemic Lupus Erythematosus Specially Refractory Type

Refractory Anemia in Systemic Lupus Erythematosis
Samsung Medical Center

Active, not recruiting

Patients With Refractory, Metastatic Cancer Harboring KIT Mutation or Amplification to Investigate the Clinical Efficacy and Safety of Imatinib Therapy

Advanced, Refractory Cancer

Korea, Republic of
iCell Gene Therapeutics
iCar Bio Therapeutics

Not yet recruiting

Anti-CD33 CAR-T Cells for the Treatment of Relapsed/Refractory CD33+ Acute Myeloid Leukemia

High Risk Hematologic Malignancies | Relapsed and/or Refractory Acute Myeloid Leukemia

China
National University Hospital, Singapore

Recruiting

Selinexor & Talazoparib in Advanced Refractory Solid Tumors; Advanced/Metastatic Triple Negative Breast Cancer (START)

Advanced Refractory Solid Tumors | Advanced Triple Negative Breast Cancers | Metastatic Triple Negative Breast Cancers

Singapore
Genentech, Inc.

Recruiting

A Study of RO7617991 in Patients With Locally Advanced or Metastatic MAGE-A4-Positive Solid Tumors

Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer

Australia
Caribou Biosciences, Inc.

Enrolling by invitation

Long-Term Follow-up Study (LTFS)

Lymphoma | Lymphoma, Non-Hodgkin | B Cell Lymphoma | Non-Hodgkin Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Hematologic Malignancy | Relapsed/Refractory Multiple Myeloma | Relapsed/Refractory Acute Myeloid Leukemia | Relapsed Non-Hodgkin Lymphoma | B-Cell Non-Hodgkin's Lymphoma

United States
University Hospital of Cologne

Recruiting

Cologne Cohort of Neutropenic Patients (CoCoNut) (CoCoNut)

Cancer | Neutropenia | Chemotherapy | Hematological Malignancies | Immunosuppression

Germany
Catherine Bollard
Johns Hopkins University; Children's National Research Institute

Recruiting

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies (RESOLVE)

Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS

United States
Pusan National University Yangsan Hospital

Recruiting

Continuous IntraVenous Infusion of Ketamine in Terminally Ill Cancer Patients (CIVIK)

Ketamine | Refractory Cancer Pain

Korea, Republic of
Foghorn Therapeutics Inc.

Recruiting

FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies

Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Relapsed Acute Myeloid Leukemia | Relapsed Myelodysplastic Syndromes | Refractory Myelodysplastic Syndromes | Advanced Hematologic Malignancy | Relapsed Chronic Myelomonocytic Leukemia

United States
Onward Therapeutics

Recruiting

First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors

Solid Tumor | Hematological Malignancy

France
Prof. Dr. Thomas Luft

Recruiting

The Endothelial Cell Dysfunction and Outcome Project for Hematological Neoplasms (EndoCDO-H)

Endothelial Dysfunction | Hematological Neoplasm

Germany
Antengene Therapeutics Limited
Bristol-Myers Squibb

Recruiting

Safety and Preliminary Efficacy of ATG-017 Monotherapy or Combination Therapy With Nivolumab in Advanced Solid Tumors and Hematological Malignancies (ERASER)

Solid Tumor | Hematological Malignancy

Australia
Adaptimmune

Recruiting

Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination

Solid and Hematological Malignancies

United States, Spain, Canada, United Kingdom
Kite, A Gilead Company

Enrolling by invitation

Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells

Solid and Hematological Malignancies

United States, Netherlands, Japan, Australia, France, Israel, Germany, Canada, United Kingdom
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Food and Acid Reducing Agents on the Absorption of Capivasertib in Healthy Participants

Solid and Hematological Malignancies

Germany
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients

Hematological Malignancy

United States
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Completed

Umbilical Cord Blood Transplant for Children With Myeloid Hematological Malignancies (UCAML)

Myeloid Hematological Malignancies

United States
Centre Hospitalier Universitaire de Besancon

Terminated

Study of T Specific Immune Response Against Delta-CD20 Peptide in Hematological Malignancies B (Epitopes-LNH01)

Hematological Malignancies B

France
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Systemic Mastocytosis | Recurrent... and other conditions

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelodysplastic Syndrome

Severe Aplastic Anemia (SAA) | Myelodysplastic Syndrome (MDS) With Refractory Anemia (RA)

United States
Celgene

Active, not recruiting

A Study to Evaluate Long-term Safety of CC-486 (Oral Azacitidine) in Subjects With Hematological Disorders

Neoplasms | Hematologic Malignancies | Hematologic Neoplasm

United Kingdom, United States
Vlad Radulescu

Completed

Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis/Treatment

Cancer | Infertility | Rheumatologic Disorder | Hematologic Disorder

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Active, not recruiting

Positive Psychology Intervention In HSCT (PATH-3)

Hematopoietic/Lymphoid Cancer | Hematologic Malignancy | Blood Cancer

United States
Inova Health Care Services

Recruiting

A Pilot Prospective Clinical Trial Using Remote Monitoring for Cancer Patients Undergoing Outpatient Chemotherapy

Solid Tumor | Hematological Malignancy

United States
Institut Bergonié

Recruiting

Bergonie Institut Profiling : Fighting Cancer by Matching Molecular Alterations and Drugs in Early Phase Trials (BIP)

Solid Tumor | Hematological Malignancy

France
Adaptimmune

Terminated

Long Term Follow up of Subjects Exposed to Genetically Engineered T Cell Receptors

Solid and Hematological Malignancies

United States, Canada
Dana-Farber Cancer Institute
National Institutes of Health (NIH); Brigham and Women's Hospital

Completed

Vaccination With GM-K562 Cells in Patients With Advanced Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) After Allogeneic Hematopoetic Stem Cell Transplantation

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome-Refractory Anemia With Excess Blasts

United States
Hannover Medical School
University Hospital, Ghent; Johann Wolfgang Goethe University Hospital; University... and other collaborators

Unknown

Treatment of Adults Aged Up to 60 Years With De Novo Acute Myeloblastic Leukaemia,Secondary AML, or RAEB-T

De Novo Akute Myeloid Leukemia (AML) | Secondary Acute Myeloid Leukemia (AML) | Refractory Anemia With Excess of Blasts in Transformation

Germany
Shanghai Yuyao Biotech Co., Ltd.

Recruiting

An Open-Label, Multicenter, Phase I Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of YY201 in Patients With Advanced Solid Tumors and Hematological Malignancies

Advanced Solid Tumor | Hematological Malignancy

China
Century Therapeutics, Inc.

Recruiting

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

Hematological Malignancy | Solid Tumor Malignancy

United States
Spectrum Pharmaceuticals, Inc
Onxeo

Completed

A Study of Belinostat in Combination With Warfarin in Patients With Solid Tumors or Hematological Malignancies

Solid Tumor | Hematological Malignancy

United States
Roswell Park Cancer Institute

Recruiting

Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies

Recurrent Mantle Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Mantle Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell... and other conditions

United States
Mayo Clinic

Recruiting

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Mantle Cell Lymphoma | Recurrent... and other conditions

United States
Immatics US, Inc.

Completed

Human Leukocyte Antigen Typing and Tumor Antigen Expression Profiling

Neoplasms | Adult Solid Tumor | Refractory Cancer | Recurrent Cancer

United States
University Hospital, Montpellier
Centre Hospitalier Universitaire de Nīmes; Institut du Cancer de Montpellier; Oncopole Toulouse

Completed

Intrathecal Analgesia Effects on Cancer Patients Discomfort Symptoms (IT-ESAS)

Refractory Cancer Pain | Intrathecal Analgesia

France

Clinical Trials on Refractory Hematologic Cancer

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