Clinical Trials on Refractory WHO Grade 1 Glioma

Total 738 results

Case Comprehensive Cancer Center

Recruiting

Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

High Grade Glioma

United States
University of Cincinnati

Completed

Radiation Planning Study for High Grade Brain Tumors

High Grade Glioma

United States
Daniel Morgenstern
The Hospital for Sick Children

Recruiting

Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas (VICTORY)

Low-grade Glioma

Canada
University of Alabama at Birmingham

Recruiting

Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma

High Grade Glioma

United States
Weiguo Zhang

Recruiting

How the Precise Habitats Can Predict the IDH Mutation Status and Prognosis of the Patients With High-grade Gliomas

High-grade Glioma

China
Laminar Pharmaceuticals
Dana-Farber Cancer Institute; Hackensack Meridian Health; Laminar Pharma Inc

Recruiting

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

High-grade Glioma | Solid Tumor, Unspecified, Child

United States
Nationwide Children's Hospital

Not yet recruiting

Intra-tumoral Injection of Natural Killer Cells in High-Grade Gliomas (NK HGG)

High Grade Glioma

United States
James Felker
National Cancer Institute (NCI); Connor's Cure

Recruiting

A Vaccine Trial for Low Grade Gliomas

Low Grade Glioma

United States
WPD Pharmaceuticals Sp. z o.o.
Worldwide Clinical Trials

Withdrawn

A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas

High Grade Glioma
University of California, San Francisco
National Cancer Institute (NCI); Ipsen

Completed

Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade Glioma

High Grade Glioma

United States
University Hospital, Basel, Switzerland
University Basel, Department of Sport, Exercise and Health, Division of Sport...

Completed

Glioma and Exercising

High Grade Glioma

Switzerland
Centre Oscar Lambret
National Cancer Institute, France; Pierre Fabre Laboratories

Completed

Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma (OVIMA-1210)

Low-Grade Glioma

France
NYU Langone Health
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Terminated

Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas

neurofibromatosis1 (NF1) | Recurrent or Progressive Optic Pathway Gliomas (OPG) | Recurrent or Progressive Low-grade Glioma

United States
Children's Hospital Medical Center, Cincinnati
Genentech, Inc.

Completed

A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas

Diffuse Intrinsic Pontine Glioma | Newly Diagnosed High-Grade Gliomas

United States
National Cancer Institute (NCI)

Completed

Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma

Glioma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Oligodendrogliomas | Astrocytoma, Grades II, III and IV

United States
Fondazione Italiana Linfomi ONLUS

Completed

"MIRO" Molecularly Oriented Immuno-radio-therapy (FIL_MIRO)

Follicular Lymphoma, Grade 1 | Follicular Lymphoma, Grade 2 | Follicular Lymphoma Grade 3A

Italy
Massachusetts General Hospital
GlaxoSmithKline

Recruiting

Niraparib In Recurrent IDH 1/2 Gliomas

Recurrent Glioma | Low-grade Glioma | Glioma, Malignant | IDH2 Gene Mutation | IDH1 Mutation

United States
University of Pennsylvania

Completed

CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

United States
Chinese PLA General Hospital

Unknown

Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
David Bond, MD

Recruiting

Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
Erasmus Medical Center
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Leiden University... and other collaborators

Recruiting

Radiotherapy in IDH Mutated Glioma: Evaluation of Late Outcomes (RIGEL)

Oligodendroglioma | Astrocytoma, Grade III | Astrocytoma, Grade II | Oligodendroglioma, Anaplastic

Netherlands
Beijing Sanbo Brain Hospital

Completed

Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas

Low-grade Glioma | Pediatric Brain Tumor

China
European Organisation for Research and Treatment...
Cooperative Trials Group for Neuro-Oncology (COGNO)

Terminated

Trial in Low Grade Glioma Patients: Wait or Treat (IWOT)

Temozolomide | Low-grade Glioma | Phase III | Wait or Treat

Spain, Australia, Switzerland, France, Belgium, Italy, Austria, Netherlands, United Kingdom, Denmark
Memorial Sloan Kettering Cancer Center
Fox Chase Cancer Center; Pharmacyclics LLC.

Terminated

Ibrutinib for Patients With Follicular Lymphoma Without Complete Response to Initial Chemoimmunotherapy

Follicular Lymphoma | Follicular Lymphoma, Grade 1 | Follicular Lymphoma, Grade 2 | Follicular Lymphoma Grade IIIa

United States
St. Olavs Hospital
Norwegian University of Science and Technology

Recruiting

68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 Glioma

High Grade Glioma

Norway
Central Hospital, Nancy, France

Recruiting

Contribution of Cerebral 18F-DOPA PET-CT Scan in High-grade Recurrent Gliomas (DORA)

High Grade Glioma

France
Nader Sanai
InSightec; SonALAsense, Inc.; Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma

High Grade Glioma

United States
The First People's Hospital of Lianyungang
The Affiliated Hospital of Qingdao University; Shandong Cancer Hospital and... and other collaborators

Unknown

Apatinib and Irinotecan in Treating Patients With Recurrent High-grade Glioma

High-grade Glioma

China
Institut Curie

Terminated

AsiDNA Children, Adolescents and Young Adults (AsiDNA)

Recurrent High-grade Glioma

France
Duke University
Genentech, Inc.

Completed

Bevacizumab Beyond Progression (BBP) (BBP)

Glioblastoma | Malignant Glioma | Gliosarcoma | Grade 4 Malignant Glioma

United States
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | Prolymphocytic Leukemia and other conditions

China
Stony Brook University
Garnett McKeen Laboratory Inc.

Completed

Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA (DESSTINI_A)

Glioblastoma Multiform (Grade IV Astrocytoma)

United States
City of Hope Medical Center

Completed

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

Recurrent High Grade Glioma | Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Recurrent Grade III Glioma | Adult Brain Tumor | Recurrent Grade IV Glioma | Adult Anaplastic...

United States
Krankenhaus Barmherzige Schwestern Linz
Medical University of Vienna

Completed

TRICIN: Prospective Study on the Efficacy of Single Topical Trichloroacetic Acid (TCA) 85% in the Treatment of Cervical Intraepithelial Neoplasia (CIN 1/2) (TRICIN)

Cervical Intraepithelial Neoplasia Grade 1 | Cervical Intraepithelial Neoplasia Grade 2

Austria
National Cancer Institute (NCI)

Active, not recruiting

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Malignant Glioma | Recurrent Childhood Ependymoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent... and other conditions

United States, Puerto Rico
Alpheus Medical, Inc.

Active, not recruiting

Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma

High Grade Glioma

United States
University Hospital, Montpellier

Completed

Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas (SPECIFY)

Low-grade Glioma

France
Duke University

Not yet recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252 (PuMP)

Recurrent High Grade Glioma
Chinese PLA General Hospital

Completed

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
The Second Affiliated Hospital of Henan University...
Xuzhou Medical University; Xinqiao Hospital of Chongqing

Unknown

Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma (MatchCART)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19 (CART19)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
K2M, Inc.

Terminated

Comparison of Complication Rates Between Lateral Approaches to the Lumbar Spine (RAVINE)

Degenerative Disc Disease | Grade 1 Spondylolisthesis
University of Washington
Bristol-Myers Squibb

Active, not recruiting

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory Plasma Cell Myeloma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenström Macroglobulinemia and other conditions

United States
Case Comprehensive Cancer Center
Burkhardt Brain Tumor and Neuro-Oncology Center

Recruiting

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

Glioblastoma | High Grade Glioma

United States
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR); Sunnybrook Research Institute

Recruiting

Glioma Supra Marginal Incision Trial (G-SUMIT)

High Grade Glioma

Canada, United States
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK; Experimental...

Active, not recruiting

Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study) (PRaM-GBM)

High Grade Glioma

United Kingdom
Day One Biopharmaceuticals, Inc.
Pacific Pediatric Neuro-Oncology Consortium

Recruiting

A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors (FIREFLY-1)

Advanced Solid Tumor | Low-grade Glioma

United States, Israel, Korea, Republic of, Denmark, Singapore, Netherlands, Canada, Australia, Germany, Switzerland, United Kingdom
University of California, San Francisco
Merck Sharp & Dohme LLC

Terminated

Ovarian Aging in Low Grade Glioma (LGG) Treated With Temozolomide (OVA-LGG)

Low Grade Glioma

United States
Diffusion Pharmaceuticals Inc

Terminated

Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma

High Grade Glioma

United States

Clinical Trials on Refractory WHO Grade 1 Glioma

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