Clinical Trials on Relapsed/Refractory Hematological Malignancies

Total 3045 results

Scripps Translational Science Institute

Completed

Scripps Tumorgraft Study

Solid Tumor Malignancy or Hematologic Malignancy

United States
NYU Langone Health

Terminated

Study of Nonmyeloablative Peripheral Blood Stem Cell Transplant With High-dose Posttransplantation Cyclophosphamide in Hematopoietic Malignancies Including Those That Are Challenging to Engraft

Hematopoietic Malignancies

United States
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.

Completed

Cancer Patients' Performance Status Assessed Using Cardiopulmonary Exercise Testing and Wearable Data Generation

Hematologic Malignancies | Malignant Solid Tumor

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Allogeneic Hematopoietic Stem Cell Transplantation for High-Risk Hematologic Malignancies Using One Haploidentical Donor

Hematopoietic/Lymphoid Cancer

United States
Henan Cancer Hospital
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

RD13-02 for Patients With r/r CD7+ T Cell Hematologic Malignancies

Hematologic Malignancies

China
National Cancer Institute (NCI)

Enrolling by invitation

Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials

Solid Tumors | Hematologic Malignancies | Pediatric Cancers

United States
Memorial Sloan Kettering Cancer Center

Completed

Feasibility and Safety of Functional Performance Testing in Patients Undergoing Hematopoietic Cell Transplantation

Lymphoma | Acute Myeloid Leukemia | Leukemia | Myelodysplastic Syndrome | Myeloma | Hematological Malignancy

United States
National Cancer Institute (NCI)

Recruiting

Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies

Lymphoma | Non-Hodgkin Lymphoma | NHL | Hematologic Malignancies | Lymphoid Malignancies

United States
Eli Lilly and Company
Children's Oncology Group

Completed

A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

Recurrent Tumor | Pediatric Solid Tumor | Refractory Tumor | CNS Malignancies

United States
Stanford University
Amgen; Pediatric Oncology Experimental Therapeutics Investigators' Consortium

Completed

Carfilzomib in Combination With Cyclophosphamide and Etoposide for Children (POE14-01)

Refractory Leukemia | Refractory Solid Tumors | Relapsed Solid Tumors | Relapsed Leukemia

United States, Canada
CASI Pharmaceuticals, Inc.

Completed

A Phase 1 Study of MKC-1 in Patients With Refractory Hematologic Malignancies

Myelodysplasia | Hematological Malignancies | Agnogenic Myeloid Metaplasia

Canada
Medical College of Wisconsin

Recruiting

Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

Multiple Myeloma | Hematological Malignancy

United States
Westlake Therapeutics

Recruiting

Safety, Tolerability and Preliminary Efficacy of Engineered Red Blood Cell in Patients With Advanced Malignancies (Reboot-101)

Cancer | Solid Tumor | Hematologic Malignancy

China
City of Hope Medical Center
National Institute on Aging (NIA)

Active, not recruiting

Technology to Assess Vulnerable Older Adults With Cancer and Their Caregivers

Cancer | Solid Tumor | Hematologic Malignancy

United States
Northwestern University
National Cancer Institute (NCI); Hackensack Meridian Health; Lombardi Comprehensive...

Completed

Expressive Helping for Stem Cell Transplant Patients

Stem Cell Transplantation | Hematologic Malignancy

United States
Incyte Corporation

Completed

A Dose-escalation Study in Subjects With Advanced Malignancies

Solid Tumors and Hematologic Malignancy

United States
Elisabethinen Hospital
Pfizer

Terminated

Anidulafungin in Patients With Hematologic Malignancies (ECALTA)

Hematologic Malignancies

Austria
University Hospital, Geneva

Not yet recruiting

Prophylactic CD45RA-depleted DLI After Haploidentical Transplantation/RIC

Hematologic Malignancy | Haplo-identical Stem Cell Transplantation
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Active, not recruiting

Positive Psychology Intervention In HSCT (PATH-3)

Hematopoietic/Lymphoid Cancer | Hematologic Malignancy | Blood Cancer

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Beth Israel Deaconess Medical Center; Brigham...

Completed

Donor Dendritic Cells And Donor Lymphocytes in Patients With Relapsed Hematologic Malignancies After Allogeneic Transplant

Hematologic Malignancy

United States
Nationwide Children's Hospital

Recruiting

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT) (TB19DHCT)

Hematologic Malignancy | Hematopoietic Stem Cell Transplantation

United States
Peking University People's Hospital

Recruiting

Beijing Protocol in Patients Receiving More Than 5/10 HLA-mismatched Allo-HSCT

Hematologic Malignancy | Stem Cell Transplant Complications

China
Duke University

Recruiting

Survivorship Post-HCT Optimization Program (S-POP)

Hematologic Malignancy

United States
Dana-Farber Cancer Institute

Completed

Patient-Centered Care for the Older Adult With Hematologic Malignancy

Hematologic Malignancy

United States
University of Colorado, Denver

Not yet recruiting

TCR Alpha/Beta and CD19-deplete Haplo-HSCT

Hematologic Malignancy | Pediatric Patients | Other Hematologic Condition

United States
The Catholic University of Korea

Unknown

Efficacy Study of Ramosetron in the Setting of Hematopoietic Stem Cell Transplantation

Hematologic Malignancies

Korea, Republic of
Fate Therapeutics
Dana-Farber Cancer Institute

Completed

Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.

Hematologic Malignancies | Allogeneic Stem Cell Transplantation

United States
M.D. Anderson Cancer Center

Recruiting

Outcomes After Chimeric Antigen Receptor Therapy and Radiation Therapy for Hematologic Malignancies

Hematopoietic and Lymphoid Cell Neoplasm

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Recruiting

Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies

Hematologic Malignancies

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation

Hematologic Malignancies

United States
Jazz Pharmaceuticals
The Lymphoma Academic Research Organisation; EUSA SAS

Completed

Phase I Study of mPEG-R-Crisantaspase Given IV

Hematologic Malignancies

France
Kiadis Pharma

Completed

Dose-ranging Study of a Single Administration of T-cell Add-back Depleted of Host Alloreactive Cells in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Hematologic Diseases | Hematologic Malignancies

Canada
Case Comprehensive Cancer Center
Florida International University; Community Foundation of Broward

Recruiting

Individualized Treatments in Adults With Relapsed/Refractory Cancers

Relapsed Cancer | Refractory Cancer

United States
Joaquina Baranda

Active, not recruiting

A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Cancer | Solid Tumor | Malignant Disease | Relapsed Hematologic Malignancy

United States
Duke University
Blue Spark Technologies

Not yet recruiting

VitalTraq for the Detection of CRS

Hematologic Malignancy
Massachusetts General Hospital
The Leukemia and Lymphoma Society

Recruiting

Mobile CARE-App to Promote Coping for Caregivers of Patients Receiving Stem Cell Transplant

Hematologic Malignancy | Bone Marrow Transplant Complications

United States
Aperture Medical Technology, LLC

Recruiting

A Prospective Study of Conventional Bone Marrow Biopsy Versus Portomar(TM) Biopsy

Hematologic Malignancy

United States
Sofia Ramström

Enrolling by invitation

Function of Platelets Used for Transfusions

Thrombocytopenia | Hematologic Malignancy

Sweden
Xinxiang medical university

Recruiting

NKG2D-CAR-NK92 Cells Immunotherapy for Solid Tumors

Relapsed/Refractory Solid Tumors

China
Amgen

Completed

Chemotherapy Related Anemia

Anemia | Non-Myeloid Malignancies
Amgen

Completed

A Study of Darbepoetin Alfa for the Treatment of Anemia in Subjects With Non-Myeloid Malignancy Receiving Multicycle Chemotherapy

Anemia | Non-Myeloid Malignancies
University of Chicago

Terminated

Phase I Study to Assess the Tolerability and Efficacy of Nivolumab in Patients With Hematologic Malignancies

Hematologic Malignancies

United States
Indiana University School of Medicine
National Institutes of Health (NIH)

Withdrawn

In-Vitro Studies in Depletion of Haplotype Mismatched Alloreactive T Cells

Hematopoietic Stem Cell Transplantation | Hematologic Malignancies
Malaghan Institute of Medical Research

Recruiting

Continuous Temperature Monitoring for tHe Early Recognition of Febrile Neutropenia in Haematological MALignancies (THERMAL)

Lymphoma | Leukemia | Myeloma | Temperature Change, Body | Haematological Malignancy

New Zealand
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Clinical Study Comparing Different Strategies to Increase Adherence to Oral Therapies in Oncohematology

Cancer | Solid Tumor | Hematologic Malignancy | Oral Drug Administration

Italy
Emory University
Dana-Farber Cancer Institute; University of Massachusetts, Worcester

Completed

Mindfulness Meditation in Bone Marrow Transplantation

Stem Cell Transplantation | Bone Marrow Transplantation | Hematologic Malignancy

United States
Dartmouth-Hitchcock Medical Center

Recruiting

Immune Profiling for Cancer Immunotherapy Response

Cancer | Hematologic Malignancy | Blood Cancer | Tumor, Solid

United States
Brigham and Women's Hospital
Harvard Medical School (HMS and HSDM)

Completed

A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients (PATH II)

Hematopoietic/Lymphoid Cancer | Hematologic Malignancy | Blood Cancer

United States
University of California, San Diego

Terminated

An Open Label Navigational Investigation of Molecular Profile-Related Evidence Determining Individualized Cancer Therapy for Patients With Incurable Hematologic Malignancies (I-PREDICT Heme) (I-PREDICT Heme)

Hematologic Cancer

United States
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART B)

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic...

Netherlands

Clinical Trials on Relapsed/Refractory Hematological Malignancies

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