Clinical Trials on Respiratory Distress Syndrome, Infant in Ireland

Total 184 results

Belfast Health and Social Care Trust
Queen's University, Belfast; NHS Blood and Transplant; Northern Ireland Clinical...

Recruiting

Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) (REALIST)

Acute Respiratory Distress Syndrome

United Kingdom
University College Dublin

Completed

Routine Or Selective Application of a Face Mask for Preterm Infants at Birth: the ROSA Trial (ROSA)

Infant, Premature, Diseases | Respiratory Distress Syndrome, Newborn | Resuscitation | Positive-Pressure Respiration | Continuous Positive Airway Pressure

Ireland
Draeger Medical Systems, Inc.

Unknown

Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates

Respiratory Distress Syndrome In Premature Infants

United States
Queen's University, Belfast
Innovate UK; Northern Ireland Clinical Trials Unit

Active, not recruiting

Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome (PHIND)

Acute Respiratory Distress Syndrome (ARDS)

United Kingdom, Ireland
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome

ARDS, Human | Mechanical Ventilation | Lung Ultrasound

Denmark, Italy, Netherlands, Belgium, Greece, Ireland, Poland
Academisch Medisch Centrum - Universiteit van Amsterdam...
University of Sao Paulo; National University of Ireland, Galway, Ireland; Carlos...

Active, not recruiting

PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia (PRoVENT-COP)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Mechanical Ventilation Complication

Netherlands, Argentina, Brazil, Ireland, Spain
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure (Preemie iNO)

Pneumonia | Sepsis | Hypertension, Pulmonary | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn | Respiratory Distress Syndrome (RDS)

United States
University of Alberta
University of Manitoba; University of British Columbia; McGill University; McMaster... and other collaborators

Recruiting

30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants (HiLo)

Premature Infant | Respiratory Distress Syndrome in Premature Infant | Neurodevelopmental Outcome

Canada, Ireland, Spain
Australian and New Zealand Intensive Care Research...

Terminated

A Multi-centre Trial of an Open Lung Strategy Including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in Patients With Acute Respiratory Distress Syndrome (PHARLAP)

Acute Respiratory Distress Syndrome

Australia, Ireland, United Kingdom, New Zealand, Saudi Arabia
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants (Surfactant 2)

Respiratory Insufficiency | Respiratory Distress Syndrome | Infant, Newborn

United States
Veru Inc.

Completed

COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111

Respiratory Distress Syndrome, Adult

United States
Windtree Therapeutics

Completed

The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational Age

Respiratory Distress Syndrome

United States, Canada, Colombia, Hungary, Chile, Ireland, Netherlands, Poland
Women and Infants Hospital of Rhode Island

Unknown

CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure (NICA)

Respiratory Distress Syndrome | Apnea of Prematurity | Prematurity

United States
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Windtree Therapeutics

Terminated

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA

Respiratory Distress Syndrome

Canada, United States, Chile, Poland
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants (Vitamin A)

Sepsis | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Respiration, Artificial | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Eli Lilly and Company

Completed

A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury

Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States, Belgium, Spain, Canada, Australia, New Zealand
NICHD Neonatal Research Network
Canadian Institutes of Health Research (CIHR); National Center for Research... and other collaborators

Terminated

Early Inhaled Nitric Oxide for Respiratory Failure in Newborns (Early iNO)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR); Medical Research Council of...

Terminated

Inhaled Nitric Oxide Study for Respiratory Failure in Newborns (NINOS)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States, Canada
University College Cork

Not yet recruiting

Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography (DiFuSE)

Gestational Diabetes | Neonatal Encephalopathy | Diastolic Dysfunction | Trisomy 21 | Transient Tachypnea of the Newborn | Small for Gestational Age at Delivery

Ireland
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE) (SAVE)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Terminated

Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)

Respiratory Insufficiency | Pulmonary Hypertension | Respiratory Distress Syndrome, Newborn | Prematurity

United States
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial (ALPS)

Pregnancy | Preterm Birth | Respiratory Distress Syndrome | Pregnancy Outcomes

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

The Budesonide in Babies (BiB) Trial (BiB)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia (BPD) | Prematurity; Extreme | Neonatal

United States
Royal College of Surgeons, Ireland
University College Dublin; Connolly Hospital Blanchardstown

Completed

A 2 Week, Crossover Trial of Dietary Nitrate in Obstructive Sleep Apnoea Syndrome (OSAS).

Obstructive Sleep Apnoea Syndrome

Ireland
University College Hospital Galway

Terminated

Awake Prone Positioning to Reduce Invasive VEntilation in COVID-19 Induced Acute Respiratory failurE (APPROVE-CARE)

COVID19 | Mechanical Ventilation Complication | ARDS, Human

Ireland
University College Hospital Galway

Recruiting

Nebulised Heparin to Reduce COVID-19 Induced Acute Lung Injury (CHARTER-Irl)

Covid19 | ARDS, Human | Ventilation Perfusion Mismatch | Lung Injury, Acute

Ireland
University College Dublin
Mater Misericordiae University Hospital; Irish Cancer Society

Recruiting

COMpassion FOcused Therapy and Breathing Pattern REtraining After Cancer Recurrence (COMFORT)

Psychological Distress | Cancer Recurrence

Ireland
Royal Liverpool University Hospital

Completed

Psychological Impact of COVID-19 on Intensive Care Survivors (PIM-COVID)

Depression | COVID-19 | Anxiety | Psychological Distress | Post-traumatic Stress Disorder | Post Intensive Care Syndrome

United Kingdom
University of Limerick

Unknown

Steps Ahead: Optimising Physical Activity and Health in Adults With Cystic Fibrosis

Cystic Fibrosis

Ireland
University of Colorado, Denver

Completed

Identifying the Most Accurate Method for Predicting the Safe Depth of Orally Placed Neonatal Endotracheal Tubes (ETT).

Ventilator Adverse Event | Infant Showing No Response to Resuscitation | Apparent Life Threatening Event in Newborn and Infant

United States, Ireland
University College Cork
Assistance Publique - Hôpitaux de Paris; KU Leuven; University of Washington; Queen... and other collaborators

Completed

Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified (CFMATTERS)

Cystic Fibrosis

Ireland
Northwell Health
Staten Island University Hospital

Completed

The Use of Heliox in Obstructive Sleep Apnea Syndrome (HOSA)

Obstructive Sleep Apnea Syndrome

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study (PPHN)

Persistent Fetal Circulation Syndrome | Infant, Small for Gestational Age | Persistent Pulmonary Hypertension of Newborn | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Rhode Island Hospital
Brown University

Not yet recruiting

Long COVID-19 Intervention Using Digital Health & Technology (LIGHT)

Long COVID | Distress Tolerance

United States
Pulmatrix Inc.
Celerion

Completed

A Safety and Tolerability Study OF PUR118 In Subjects With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Children's Health Ireland
Queen's University, Belfast; Cystic Fibrosis Foundation; European Cystic Fibrosis...

Active, not recruiting

COVID-19 Antibody Responses in Cystic Fibrosis (CAR-CF)

COVID-19 | Cystic Fibrosis

Ireland
AlgiPharma AS

Completed

A Cross-over Study of OligoG in Subjects With Cystic Fibrosis. Fibrosis (OligoG)

Cystic Fibrosis

United Kingdom, Ireland
University College Dublin
Wellcome Trust; Health Research Board, Ireland; National Maternity Hospital,... and other collaborators

Recruiting

Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants (PARENT)

Late-Onset Neonatal Sepsis | Necrotising Enterocolitis | Culture Negative Neonatal Sepsis

Ireland
Children's Health Ireland
Belfast Health and Social Care Trust; University of Edinburgh; University Hospital... and other collaborators

Recruiting

Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome (REFRESHED)

Quality of Life | Obstructive Sleep Apnea | Down Syndrome | Behavior | Adherence, Treatment

United Kingdom, Ireland
Cardiovascular Research Institute Dublin

Active, not recruiting

Study of HEarT DiseAse and ImmuNiTy After COVID-19 in Ireland (SETANTA)

Covid19 | Cardiomyopathies | SARS-CoV Infection

Ireland
St Vincent's University Hospital, Ireland

Withdrawn

Effect of CPAP vs Control on Nocturnal Dipping in Normotensive Patients With Obstructive Sleep Apnea

Sleep Apnea, Obstructive

Ireland
Women and Infants Hospital of Rhode Island

Completed

Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator

Bronchopulmonary Dysplasia

United States
Celtaxsys, Inc.
Celerion

Completed

Phase 1 Study Assessing the Safety and Tolerability of CTX-4430 in Cystic Fibrosis Patients

Cystic Fibrosis

United Kingdom
Procter and Gamble
ARYx Therapeutics

Terminated

A Dose-Ranging Study of ATI 7505 in Patients With Postprandial Distress Syndrome

Post Prandial Distress Syndrome

United States, Canada, United Kingdom
St Vincent's University Hospital, Ireland
ResMed

Suspended

Adaptive Servo Ventilation (ASV) in Heart Failure

Acute Decompensated Heart Failure | Sleep Disordered Breathing

Ireland
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Dexamethasone Therapy in VLBW Infants at Risk of CLD (Dexamethasone)

Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Rhode Island Hospital
University of Illinois at Chicago

Completed

Sodium Channel Splicing in Obstructive Sleep Apnea (SOCS-OSA)

Sleep Apnea Syndromes

United States
University College, London
University of Oxford; University of Plymouth; University of Birmingham; University... and other collaborators

Completed

Use of Decision Support in the Management of Labour (INFANT)

Fetal Intrauterine Distress First Noted During Labor and or Delivery in Liveborn Infant | Team Based on Their Existing Guidelines and the Woman Consents to Have EFM and EFM is | Possible

United Kingdom, Ireland
Children's Hospital of Philadelphia
Rhode Island Hospital; Children's Miracle Network; American Respiratory Care...

Recruiting

NAVA vs. CMV Crossover in Severe BPD

Bronchopulmonary Dysplasia | Mechanical Ventilation | Neurally Adjusted Ventilatory Assist

United States

Clinical Trials on Respiratory Distress Syndrome, Infant in Ireland

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