Clinical Trials on Retinal Vascular Disorders in United Kingdom

Total 74324 results

Bayer

Completed

Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA) (AURA)

Ophthalmology, Macular Degeneration

Japan, France, Germany, Australia, Italy, United Kingdom, Venezuela, Ireland, Netherlands, Canada
Azienda Ospedaliera Universitaria Mater Domini,...

Recruiting

Photobiomodulation in Dry Age Related Macular Degeneration (DRUSEN)

Age-Related Macular Degeneration

France, Italy, Turkey, United Kingdom
Bayer

Completed

A Study to Assess the Effectiveness of Aflibercept in Routine Clinical Practice in Patients With Diabetic Macular Oedema (DRAKO)

Macular Edema

United Kingdom
Bayer
Regeneron Pharmaceuticals

Terminated

A Study to Learn How Well Aflibercept Injected Into the Eye Works and How Safe it is When Given in Customized Treatment Intervals in Patients With an Eye Disease Called Neovascular Age-related Macular Degeneration After Start of Treatment (XPAND)

Neovascular (Wet) Age-related Macular Degeneration

Canada, United Kingdom
National Eye Institute (NEI)

Completed

Minocycline to Treat Branch Retinal Vein Occlusion

Retinal Vein Occlusion

United States, United Kingdom
Outlook Therapeutics, Inc.

Active, not recruiting

A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders (NORSE SEVEN)

Age-Related Macular Degeneration | Diabetic Macular Edema | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration | BRVO - Branch Retinal Vein Occlusion

United States
Moorfields Eye Hospital NHS Foundation Trust
Novartis

Completed

Ranibizumab in Diabetic Vitrectomy. A Prospective, Randomised Controlled Trial of Ranibizumab Pre-treatment in Diabetic Vitrectomy - a Pilot Study (RaDiVit)

Diabetic Retinopathy | Retinal Neovascularisation

United Kingdom
Astellas Institute for Regenerative Medicine

Completed

A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
NeoVista

Unknown

A Study of the NeoVista Ophthalmic System for the Treatment of Subfoveal CNV Associated With Wet AMD in Patients That Require Persistent Anti-VEGF Therapy (MERITAGE)

Age Related Macular Degeneration

United Kingdom, Israel, United States
King's College Hospital NHS Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Moorfields Eye Hospital... and other collaborators

Recruiting

Suprachoroidal Visco-buckling for the Treatment of Rhegmatogenous Retinal Detachment (VIKING)

Retinal Detachment With Break

United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With Central Retinal Vein Occlusion (CRVO) (COMRADE-C)

Central Retinal Vein Occlusion | Macular Edema | Visual Impairment

Germany, United Kingdom, Hungary, Poland
University of Aberdeen
NHS Grampian; Chief Scientist Office of the Scottish Government

Completed

Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study (FILMS)

Stage 2 or 3 Full Thickness Macular Hole

United Kingdom, Ireland
Hoffmann-La Roche

Completed

A Study of RO6867461 Administered in Single- and Multiple-Ascending Doses in Patients With Wet Age-Related Macular Degeneration

Macular Degeneration

United States, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With Branch Retinal Vein Occlusion (BRVO) (COMRADE-B)

Macular Edema | Visual Impairment | Branch Retinal Vein Occlusion

Germany, United Kingdom, Hungary, Poland, Czech Republic
Bayer
Regeneron Pharmaceuticals

Completed

Evaluation of Changes in Visual Acuity in Patients With Diabetic Macular Edema (DME) Starting Treatment With an Approved Anti-VEGF Therapy (POLARIS)

Macular Degeneration | Macular Edema | Ophthalmology

Slovakia, France, Germany, Spain, Russian Federation, United Kingdom, Portugal, Greece
Astellas Institute for Regenerative Medicine

Completed

Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
University College, London

Completed

The EASE Study - Human Factor and Usability Testing of a Binocular OCT System (EASE)

Glaucoma | Strabismus | Healthy Volunteers | Retinal Disease

United Kingdom
Emory University

Completed

DETECT and Retinal Outcomes in Hypertension

Hypertension | Cognitive Impairment | Retinal Disorder

United States
Oxford University Hospitals NHS Trust

Recruiting

Performance of Long-wavelength Autofluorescence Imaging

Retinal Degeneration | Retinal Dystrophies | Retinal Disease

United Kingdom
Julie Dawson

Completed

RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery. (CMO)

Open Angle Glaucoma and Cataract

United Kingdom
Boehringer Ingelheim

Completed

A Study to Test Different Doses of BI 836880 in Patients With an Eye Disease Called Wet Age-related Macular Degeneration (wAMD)

Wet Macular Degeneration

United Kingdom, United States, Germany
University of Oxford

Completed

Quality of Life Measures in Patients With Retinal Degeneration

Retinal Degeneration

United Kingdom
Novartis

Completed

Safety and Tolerability of an Intravenous Infusion of ACZ885 in Patients With Wet Age-Related Macular Degeneration

Wet Age-Related Macular Degeneration

United Kingdom, Switzerland
Outlook Therapeutics, Inc.

Completed

A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders

Age-related Macular Degeneration | Diabetic Macular Edema | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration | BRVO - Branch Retinal Vein Occlusion

United States
VisionCare, Inc.

Recruiting

Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration

Age-Related Macular Degeneration | AMD

Italy, Ireland, Spain, Germany, United Kingdom
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
Manhattan Eye, Ear & Throat Hospital

Unknown

ICG-Guided Photodynamic Therapy for Treatment of Retinal Capillary Abnormalities: A Pilot Study (ICGguidedPDT)

Retinal Vascular Disorders

United States
LumiThera, Inc.

Completed

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE II)

Dry Age-related Macular Degeneration

United Kingdom, Spain, France, Germany, Italy
MeiraGTx UK II Ltd
Syne Qua Non Limited

Completed

Long-Term Follow-Up Gene Therapy Study for Leber Congenital Amaurosis OPTIRPE65 (Retinal Dystrophy Associated With Defects in RPE65)

Eye Diseases | Retinal Diseases | Eye Diseases, Hereditary | Leber Congenital Amaurosis (LCA)

United States, United Kingdom
Justis Ehlers
Regeneron Pharmaceuticals

Completed

Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVO (PERMEATE)

Central Retinal Vein Occlusion | Diabetic Macular Edema | Retinal Vein Occlusion | Branch Retinal Vein Occlusion

United States
University of Southampton
King's College London; Medical University of Vienna; University of Michigan; Imperial... and other collaborators

Active, not recruiting

Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLE (PINNACLE)

Age-related Macular Degeneration

Austria, Switzerland, United Kingdom
Belfast Health and Social Care Trust
National Institute for Health Research, United Kingdom

Completed

Effectiveness of Multimodal Imaging for the Evaluation of Retinal Oedema And New vesseLs in Diabetic Retinopathy (EMERALD)

Diabetic Macular Edema | Proliferative Diabetic Retinopathy

United Kingdom
GlaxoSmithKline

Terminated

GW824575 First Time in Human

Retinal Diseases

United Kingdom
Bayer

Completed

Evaluation of a Treat and Extend Regimen of Intravitreal Aflibercept for Macular Edema Secondary to CRVO (CENTERA)

Central Retinal Vein Occlusion

France, Canada, Denmark, Germany, Italy, Spain, United Kingdom, Australia
Targeted Therapy Technologies, LLC

Recruiting

Phase I Study of Episcleral Celecoxib for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole

Macula Edema | Epiretinal Membrane | Branch Retinal Vein Occlusion | Radiation Retinopathy | Central Serous Retinopathy With Pit of Optic Disc | Commotio Retinae | Vitritis

United States
Novartis Pharmaceuticals

Completed

Ranibizumab Treatment of Diabetic Macular Oedema With Bimonthly Monitoring After a Phase of Initial Treatment (RELIGHT)

Diabetic Retinopathy | Macular Oedema

United Kingdom
Maturi, Raj K., M.D., P.C.

Completed

Single Site, Masked, Randomized, Controlled Study to Assess Efficacy of Osurdex as Adjunct to Avastin Compared With Avastin Alone in the Treatment of Patients With Macular Edema Due to Central or Branch Retinal Vein Occlusion

Retinal Vein Occlusions

United States
Northern California Retina Vitreous Associates
Regeneron Pharmaceuticals

Completed

NEWTON: Aflibercept Injection for Previously Treated Macular Edema Associated With Central Retinal Vein Occlusions (NEWTON)

Macular Edema With Central Retinal Vein Occlusions

United States
Novartis Pharmaceuticals

Terminated

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion (RAPTOR)

Branch Retinal Vein Occlusion

China, Austria, Czechia, Russian Federation, Taiwan, United Kingdom, Canada, Japan, United States, France, Israel, Germany, Italy, Hong Kong, Spain, Denmark, Slovakia, Puerto Rico, Switzerland
Retina Vitreous Associates of Florida

Completed

Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival

Age-related Macular Degeneration | Central Retinal Vein Occlusion | Diabetic Macular Edema

United States
Novartis Pharmaceuticals

Completed

Ranibizumab Intravitreal Injections in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRYSTAL)

Central Retinal Vein Occlusion | Macular Edema

Greece, Hungary, Turkey, Australia, Austria, Netherlands, United Kingdom, Italy, Spain, Ireland, Portugal, Slovakia, Canada, Switzerland, Czech Republic, Poland, Denmark, Sweden
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Targeted Therapy Technologies, LLC

Unknown

Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole

Macular Edema | Epiretinal Membrane | Branch Retinal Vein Occlusion | Radiation Retinopathy | Central Serous Retinopathy With Pit of Optic Disc | Commotio Retinae | Vitritis

United States
Retina Associates of Florida, P.A.

Completed

REtinal Vein OccLUsion Treatment With Scatter Laser Guided by UWFA in combiNAtion With Ranibizumab Study (Revolution)

Macular Edema | Branch Retinal Vein Occlusion

United States
Moorfields Eye Hospital NHS Foundation Trust

Completed

Adaptive Optics in PVR

Retinal Detachment

United Kingdom
Bayer

Completed

Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease (XTEND)

Wet Age-related Macular Degeneration

Canada, Spain, Sweden, Belgium, Argentina, Italy, Korea, Republic of, United Kingdom, China, Denmark, France, Norway, Colombia, Australia, Ireland, Switzerland, Thailand
Retina Research Institute, LLC
Retina-Vitreous Associates Medical Group; West Coast Retina Medical Group,...

Terminated

Ozurdex Implant for Macular Edema After Treatment Failure With Anti-VEGF

Macular Edema | Retinal Vein Occlusion (RVO)

United States
Tennessee Retina
Regeneron Pharmaceuticals

Unknown

Study of Intravitreal Aflibercept Injection for Persistent CRVO-associated Macular Edema Despite Prior Anti-VEGF Therapy

Retinal Vein Occlusion

United States
Imperial College London

Completed

Randomised Control Trial for Improving Functional Outcome From Stroke in End Stage Renal Disease Patients

Stroke | End Stage Renal Disease

United Kingdom
The Emmes Company, LLC
National Eye Institute (NEI); Allergan

Completed

The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study (SCORE)

Retinal Vein Occlusion | Macular Edema, Cystoid

United States

Clinical Trials on Retinal Vascular Disorders in United Kingdom

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