Clinical Trials on SCN8A Encephalopathy

Total 549 results

Medical University of Vienna

Recruiting

VICIS - Vienna Cirrhosis Study (VICIS)

Liver Cirrhosis | Hepatic Encephalopathy | Ascites | Portal Hypertension | Variceal Hemorrhage

Austria
Samuel Gandy

Completed

Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury

Traumatic Brain Injury | Mild Cognitive Impairment | Chronic Traumatic Encephalopathy

United States
Amgen
Ucyclyd Pharma, Inc.

Completed

A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group

Hepatic Encephalopathy | Urea Cycle Disorders

Ukraine
Tanta University

Recruiting

Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis

Hepatic Encephalopathy | Cirrhosis | Ascites | Varices | SBP - Spontaneous Bacterial Peritonitis

Egypt
Postgraduate Institute of Medical Education and...

Recruiting

Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLF

Decompensated Cirrhosis | Acute-On-Chronic Liver Failure | Hepatic Encephalopathy

India
Nationwide Children's Hospital
Cerebral Palsy Alliance

Completed

Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy

Infarction | Thrombosis | Intraventricular Hemorrhage | Neonatal Encephalopathy | Infant Development | Hydrocephalus | Infant,Premature | PVL

United States
New York Presbyterian Brooklyn Methodist Hospital

Withdrawn

Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) (HELP)

Hepatic Encephalopathy | Cirrhosis | Altered Mental Status | HE | AMS

United States
Weill Medical College of Cornell University
Bausch Health Americas, Inc.

Unknown

The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy

Liver Cirrhosis | Hepatic Encephalopathy | Hepatitis C

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis

Hepatic Encephalopathy | Cirrhosis | Portal Hypertension
Groupe Hospitalier Pitie-Salpetriere

Completed

a Vigibase Pharmacovigilance Study of ENzalutamide Drug-induced neurotoxicitY (VENDY)

Epilepsy | Prostate Cancer | Neuropathy | Encephalopathy

France
University Hospital, Toulouse

Completed

Rifaximin vs Placebo for the Prevention of Encephalopathy in Patients Treated by TIPS (PRPET)

Cirrhosis

France
University Hospital, Brest

Unknown

Dysautonomic Phenotype in Male Patients With MECP2 Mutation (MECP2BOYS)

Dysautonomia | Masculinity | MECP2-Related Severe Neonatal Encephalopathy

France
The University of Texas Health Science Center,...
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Bilirubin Neurotoxicity (BN) and Neurodevelopmental Impairment (NDI) in Extremely Preterm (EP) Infants: Avoidable by Reducing the Usual Intravenous Lipid (UL) Administration

Bilirubin Encephalopathy

United States
Simons Searchlight
Boston Children's Hospital; Geisinger Clinic; Simons Foundation

Recruiting

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

SMARCA4 Gene Mutation | DDX3X | 16P11.2 Deletion Syndrome | 16p11.2 Duplications | 1Q21.1 Deletion | 1Q21.1 Microduplication Syndrome (Disorder) | ACTL6B | ADNP | AHDC1 | ANK2 | ANKRD11 | ARID1B | ASH1L | BCL11A | CHAMP1 | CHD2 | CHD8 | CSNK2A1 | CTBP1 | CTNNB1 Gene Mutation | CUL3 | DNMT3A | DSCAM | DYRK1A | FOXP1 | GRIN2A | GRIN2B | HIVEP2-Related Intellectual... and other conditions

United States
Children's Hospital of Fudan University

Completed

A Multi-Center Cohort Study of Risk Factors and Outcomes of Encephalopathy of Prematurity in China

Encephalopathy

China
Tanta University

Recruiting

Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy:

Sepsis | Encephalopathy | Norepinephrine

Egypt
University Hospital, Toulouse

Completed

Feasibility of Critical Flicker Frequency Procedure for the Diagnosis of Minimal Encephalopathy

Cirrhosis

France
Molecular NeuroImaging
Institute for Neurodegenerative Disorders

Completed

Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects

Alzheimer's Disease (AD) | Tauopathies | Parkinson's Disease (PD) | Progressive Supranuclear Palsy (PSP) | Chronic Traumatic Encephalopathy (CTE) | Frontal Temporal Dementia (FTD) | Pick's Disease

United States
Xenon Pharmaceuticals Inc.

Terminated

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Epilepsy | Epileptic Syndromes | Disease | Epilepsy; Seizure | Epilepsy in Children

United States, Spain, Australia, Belgium, Italy
Encoded Therapeutics

Terminated

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies (ENVISION)

Dravet Syndrome

United States, Spain, Australia, United Kingdom
Universiteit Antwerpen
University Hospital, Antwerp

Recruiting

Gait in Rare Diseases (GAGA)

Tuberous Sclerosis | STXBP1 Encephalopathy With Epilepsy

Belgium
Daping Hospital and the Research Institute of Surgery...

Recruiting

Intravenous Immunoglobin Transfusion in Preterm Infants With Encephalopathy of Prematurity

Preterm Infants

China
Postgraduate Institute of Medical Education and...

Unknown

Duration of Anti-convulsant Therapy for Acute Symptomatic Seizure in Acute Encephalitis Syndrome

Seizures
Hospital Clinic of Barcelona
Hospital Universitari de Bellvitge; Maternal-Infantil Vall d´Hebron Hospital

Completed

Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation (MACHT)

Sepsis | Hepatic Encephalopathy | Renal Failure | Hyponatremia | Gastrointestinal Bleeding

Spain
OSF Healthcare System

Completed

Default Mode Network fMRI Maps as a Predictive Index of Hepatic Encephalopathy Outcome

Hepatic Encephalopathy | Hepatitis C | Cirrhosis | Nonalcoholic Steatohepatitis

United States
Protecting Brains Saving Futures

Not yet recruiting

Protecting Brains and Saving Futures - the PBSF Protocol (PBSF)

Brain Injuries | Intraventricular Hemorrhage | Congenital Heart Disease | Hypoxic-Ischemic Encephalopathy | Newborn Morbidity | Inborn Errors of Metabolism | Extracorporeal Membrane Oxygenation Complication | Respiratory Complication | Hemodynamic Instability | Nosocomial Infection | Neonatal Seizure | Brain... and other conditions

Brazil
Medical University of Vienna

Completed

Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy (ENDOvsTIPS)

Cirrhosis | Gastrointestinal Hemorrhage | Encephalopathy | Variceal Bleeding

Austria
National University Hospital, Singapore

Recruiting

CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome | Refractory Leukemia

Singapore
National University Hospital, Singapore

Recruiting

ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia. (ALaCART)

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome

Singapore
University of Bari

Completed

Minimal Hepatic Encephalopathy in Hereditary Hemorrhagic Telangiectasian (mHE-HHT)

Hepatic Encephalopathy | Minimal Brain Dysfunction

Italy
University of California, San Francisco

Terminated

BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES (TauBasket)

Nonfluent Aphasia, Progressive | Primary Tauopathies | Corticobasal Degeneration Syndrome | Frontotemporal Lobar Degeneration With Tau Inclusions | MAPT Mutation Carriers, Symptomatic | Traumatic Encephalopathy Syndrome

United States
Sun Yat-sen University

Recruiting

The Efficacy and Safety of Rifaximin Treatment

Hepatic Encephalopathy | Hepatitis B | HBV | Effect of Drug | Liver Failure, Acute on Chronic | Rifaximin

China
Qianfoshan Hospital

Not yet recruiting

Integrated Traditional Chinese and Clinical Medicine for Chronic Hepatitis B and Its Complication

Hepatic Encephalopathy | Cirrhosis, Liver | Portosystemic Shunt

China
F.D. Roosevelt Teaching Hospital with Policlinic...

Recruiting

Cirrhosis Registry of Hospitalized Patients (RH7)

Frailty | Ascites | Infection | Cirrhosis, Liver | Encephalopathy

Slovakia
Spectrum Health Hospitals
Helen DeVos Children's Hospital

Completed

RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies

Encephalopathy | Developmental Delay and Behavioral Changes | Cord Tumor Compression or Instability | Cord Tethering or Malformation

United States
Azienda Ospedaliero-Universitaria Consorziale Policlinico...
Catholic University of the Sacred Heart; Institute of Biomembranes, Bioenergetics... and other collaborators

Completed

Establishment of the Human Intestinal and Salivary Microbiota Biobank - Gastrointestinal Diseases (BIOMIS-Gastr)

Hepatic Encephalopathy | Irritable Bowel Syndrome | Clostridium Difficile Infection | Chronic Inflammatory Bowel Disease | Multi Drug Resistant Organisms

Italy
Glasgow Royal Infirmary

Completed

Alcohol: Thiamine and or Magnesium 1 (AToM1)

Magnesium Deficiency | Alcohol Withdrawal | Lactic Acidosis | Vitamin B1 Deficiency | Wernicke Encephalopathy

United Kingdom
National Institute of Neurological Disorders and...

Recruiting

Procedural Motor Memory in Long COVID-19

Ischemic Stroke | Seizure | Infectious Metabolic Encephalopathy | Viral Encephalitis, Small and Large Vessel

United States
St. Luke's Hospital, Chesterfield, Missouri
Washington University School of Medicine

Terminated

Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease (HBO)

Encephalopathy | Impaired Oxygen Delivery | White Matter Hyperintensities

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease.

HIV Infections | Encephalopathy | Radiculitis
University of Turin, Italy

Recruiting

SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies

Alzheimer Dementia | Encephalopathy | HIV-encephalopathy

Italy
Fundació Institut de Recerca de l'Hospital de la...

Completed

Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal (PREDESCI)

Hepatic Encephalopathy | Ascites | Esophageal Varices | Spontaneous Bacterial Peritonitis | Portal Hypertension Gastropathy

Spain
The University of Texas Health Science Center,...

Recruiting

The International Registry for Leigh Syndrome

Leigh Disease | Leigh Syndrome | Leigh's Necrotizing Encephalopathy | Subacute Necrotizing Encephalomyopathy | Subacute Necrotizing Encephalomyelopathy

United States
Mayo Clinic

Recruiting

Automating Delirium Severity in the ICU (ADS-ICU)

Delirium | Encephalopathy | Intensive Care Unit Delirium

United States
VA Office of Research and Development
VA Boston Healthcare System

Recruiting

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

Mild Cognitive Impairment | Mild Traumatic Brain Injury | Moderate Traumatic Brain Injury

United States
Children's Hospital of Fudan University
Second Affiliated Hospital of Wenzhou Medical University; Guangzhou Women and... and other collaborators

Terminated

Erythropoietin in Premature Infants to Prevent Encephalopathy

Premature Infant

China
MD Stem Cells

Enrolling by invitation

Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study (ACIST)

Alzheimer Disease | Traumatic Brain Injury | Autism Spectrum Disorder | Lewy Body Disease | Vascular Dementia | Autism | Dementia, Mixed | Alzheimer Dementia | Dementia, Multi-Infarct | Cadasil | Parkinson-Dementia Syndrome | Chronic Traumatic Encephalopathy | Autistic Behavior | Lewy Body Dementia With Behavioral... and other conditions

United States, United Arab Emirates
Mayo Clinic

Completed

EEG Cap for Identification of Non-Convulsive Status Epilepticus

Encephalopathy | Altered Mental Status | Nonconvulsive Status Epilepticus | Subclinical Seizure | Nonepileptic Seizures

United States
Nagoya University
Life Science Institute, Inc.

Completed

The Clinical Trial of CL2020 Cells for Neonatal Hypoxic Ischemic Encephalopathy (SHIELD)

Hypoxia-Ischemia, Brain

Japan
Number 2 Children's Hospital, Ho Chi Minh City

Recruiting

Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age

Child Development | Epilepsy; Seizure | Gene Abnormality | Early Onset Disorder

Vietnam

Clinical Trials on SCN8A Encephalopathy

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