Clinical Trials on Salivary Gland Neoplasms in United States

Total 59619 results

Roxane Laboratories

Completed

Crossover Bioequivalence Study of Cevimeline 30 mg Capsules Under Fed Conditions

Dry Mouth

United States
OncoC4, Inc.
National Cancer Institute (NCI)

Recruiting

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC (PRESERVE-001)

Cervical Cancer | Small Cell Lung Cancer | Adenoid Cystic Carcinoma | Metastatic Renal Cell Carcinoma | Metastatic Colorectal Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Breast Cancer | Advanced Solid Tumor | Metastatic Melanoma | Pancreas Cancer | Metastatic... and other conditions

United States, Australia
National Institute of Dental and Craniofacial Research...

Recruiting

The Pathogenesis and Natural History of Sjogren's Disease

Sjogren's Syndrome | Pathogenesis | Salivary Gland

United States
National Institute of Dental and Craniofacial Research...

Terminated

Evaluation of Salivary Gland Dysfunction

Sjogren's Syndrome | Salivary Gland

United States
Tufts University

Recruiting

Effect of Whitening Agent With Emulsion Gel in Saliva and Halitosis

Xerostomia | Halitosis

United States
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia

Head and Neck Cancer | Xerostomia | Oropharynx Cancer

United States
You First Services

Completed

"Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth

Xerostomia | Dry Mouth | Type 2 Diabetics

United States
National Institute of Dental and Craniofacial Research...

Recruiting

Characterization of Diseases With Salivary Gland Involvement

Healthy Volunteer | Sjogren's Syndrome | Salivary Gland Disease

United States
Arkansas Tech University

Completed

Salivary Alpha Amylase as a Biomarker of Transdermal Vagus Nerve Stimulation

No Condition Salivary Alpha Amylase

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Ovarian Endometrioid Adenocarcinoma | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Recurrent Breast Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer and other conditions

United States
Wake Forest University Health Sciences
University of Pennsylvania; NYU Langone Health; Brigham and Women's Hospital; National... and other collaborators

Active, not recruiting

Observational Study of Dental Outcomes in Head and Neck Cancer Patients (ORARAD)

Head and Neck Cancer | Xerostomia | Osteoradionecrosis | Dental Disease

United States
Royal Marsden NHS Foundation Trust

Unknown

Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United Kingdom
Loma Linda University

Withdrawn

Saliva, Hyperbaric Oxygen Therapy, & Gland Function: A Prospective Study (SHOTGUN)

Xerostomia | Osteoradionecrosis of the Jaw

United States
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations (DETERMINE)

Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Gallbladder Neoplasms | Prostatic Neoplasm | Pancreatic Neoplasm | Lung Neoplasm | Haematological Malignancy | Urinary Bladder Neoplasm | Skin Neoplasm | Salivary Gland Neoplasm

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Phase Ib Study of Erlotinib Prior to Surgery in Patients With Head and Neck Cancer

Recurrent Head and Neck Carcinoma | Recurrent Skin Carcinoma | Recurrent Salivary Gland Carcinoma | Skin Squamous Cell Carcinoma

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Xerostomia

United States, Canada
National Institute of Dental and Craniofacial Research...

Completed

DHEA Treatment for Sjogren's Syndrome

Sjogren's Syndrome | Xerostomia | Salivary Gland Disease | Lacrimal Apparatus Disease

United States
Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network

Completed

Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
National Cancer Institute (NCI)

Completed

Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
National Cancer Institute (NCI)

Completed

Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Tongue Cancer | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell... and other conditions

United States
Stanford University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma

Xerostomia

United States
National Cancer Institute (NCI)

Completed

Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer (ADCC)

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell... and other conditions

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
University of Chicago
National Cancer Institute (NCI)

Completed

PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
AstraZeneca
Daiichi Sankyo Co., Ltd.

Active, not recruiting

A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations (DPT01)

Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast

Italy, Spain, United States, France, Korea, Republic of, Japan, Canada, Denmark, Belgium
National Cancer Institute (NCI)

Completed

S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
MeiraGTx, LLC

Recruiting

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia (AQUAX2)

Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

United States, Canada
UNC Lineberger Comprehensive Cancer Center

Completed

Functional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Therapy for Head and Neck Cancers of the Oropharynx

Head and Neck Cancer | Oropharynx Cancer | Xerostomia Due to Radiotherapy

United States
Mersey Care NHS Trust
University of Central Lancashire; University of Manchester; Lancashire Care NHS... and other collaborators

Completed

Clozapine-induced Hypersalivation - Feasibility Trial (GOTHIC1)

Sialorrhea

United Kingdom
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer

Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Tongue Cancer | Salivary Gland Squamous Cell Carcinoma | Stage IV Non-small Cell Lung Cancer | Stage IV Squamous Cell Carcinoma of the Hypopharynx | Stage IV Squamous Cell Carcinoma of the Nasopharynx | Metastatic Squamous... and other conditions

United States
Acacia Pharma Ltd

Completed

Proof-of-concept (PoC) Study of APD515

Xerostomia in Advanced Cancer Patients

United Kingdom, Denmark
Ohio State University Comprehensive Cancer Center

Completed

Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.

Tongue Cancer | Salivary Gland Squamous Cell Carcinoma | Stage I Salivary Gland Cancer | Stage I Squamous Cell Carcinoma of the Hypopharynx | Stage I Squamous Cell Carcinoma of the Larynx | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Squamous Cell Carcinoma of the Nasopharynx and other conditions

United States
University of Pittsburgh

Completed

Near Infrared Fluorescence Imaging With Indocyanine Green (NIFI-ICG)

Solitary Pulmonary Nodules

United States
Mayo Clinic

Recruiting

Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Stanford University
National Cancer Institute (NCI); Agennix

Terminated

Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer or Squamous Cell Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
National Cancer Institute (NCI)

Completed

Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy (MAESTRO HN)

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Salivary Gland Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous... and other conditions

United States, China
Mayo Clinic

Recruiting

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United States, Canada
National Institute of Dental and Craniofacial Research...

Completed

Study of Oral Bacteria in Patients With Dry Mouth

Autoimmune Diseases | Xerostomia

United States
Abramson Cancer Center at Penn Medicine

Recruiting

Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES (ARCADES)

Lung Cancer | Pulmonary Nodule, Solitary

United States
Mayo Clinic

Recruiting

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Fox Chase Cancer Center
United States Department of Defense; Creatv Microtech, Inc.

Active, not recruiting

Utility of CAML as Diagnostic for Early Stage Lung Cancer

Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

United States
Brigham and Women's Hospital

Completed

Intravenous Indocyanine Green for Localization of Intra-thoracic Lesions

Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

United States
Klus Pharma Inc.

Completed

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Cervical Cancer | Head and Neck Cancer | Mucoepidermoid Carcinoma | Pancreatic Cancer | Recurrent Prostate Cancer | Lung Cancer | Rectal Cancer | Solid Tumor | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Recurrent Ovarian Carcinoma | Bladder Cancer | Skin Cancer | HER2-positive Breast Cancer | Rare Diseases | Colo-rectal Cancer and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis

Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

United States
Intuitive Surgical

Completed

Prospective Post-market Data Collection for Ion Endoluminal System to Understand CT to Body Divergence

Lung Cancer | Pulmonary Nodule, Solitary

United States
Sanjiv Sam Gambhir
National Cancer Institute (NCI)

Completed

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Tongue Cancer | Stage... and other conditions

United States
American College of Radiology - Image Metrix
GE Healthcare

Completed

GE Healthcare VolumeRAD Lung Nodule Detection Study

Multiple Pulmonary Nodules | Pulmonary Nodule, Solitary

United States, Sweden
Eunice Kennedy Shriver National Institute of Child...
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Study of Adrenal Gland Tumors

Adrenal Gland Neoplasm

United States

Clinical Trials on Salivary Gland Neoplasms in United States

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