Clinical Trials on Severe/Very Severe COVID-19 Illness in New Zealand

Total 49 results

New York University
University of Pennsylvania; Yale University

Completed

Person-Centered Care Planning and Service Engagement (PCCP)

Severe Mental Illness

United States
NeuroActiva, Inc.
Biomed Industries, Inc.

Unknown

A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19 (OPV-NA831)

Covid19 | SARS-CoV-2 | SARS-CoV Infection | SARS (Severe Acute Respiratory Syndrome)

New Zealand, United States
Kythera Biopharmaceuticals

Completed

Open-Label Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area

Moderate or Severe Submental Fullness

United States
Kythera Biopharmaceuticals

Completed

Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area (REFINE-1)

Moderate or Severe Submental Fullness

United States, Canada
Kythera Biopharmaceuticals

Completed

Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area

Moderate or Severe Submental Fullness

United States, Canada
Pfizer

Withdrawn

A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19 (EPIC-HOS)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Coronavirus Disease 2019 (COVID-19) | Immunocompromised | Hospitalization | Child, Hospitalized

United States, Bulgaria
NeuroActiva, Inc.
Biomed Industries, Inc.

Recruiting

NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection (NATADEX)

Coronavirus Infection | Severe Acute Respiratory Syndrome Coronavirus 2 | Severe Acute Respiratory Infection

United States
University of Washington
Bill and Melinda Gates Foundation

Completed

Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP)

COVID-19 | Corona Virus Infection | SARS-CoV-2 | SARS (Severe Acute Respiratory Syndrome)

United States
Rapa Therapeutics LLC
Hackensack Meridian Health

Terminated

RAPA-501-Allo Therapy of COVID-19-ARDS

Severe COVID-19 Disease

United States
National Institute of Allergy and Infectious Diseases...
Autoimmunity Centers of Excellence; Clinical Trials in Organ Transplantation...

Completed

COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C (PRISM)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Coronavirus Disease 2019 (COVID-19) | Multisystem Inflammatory Syndrome in Children (MIS-C)

United States
Chimerix

Terminated

Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Acute Lung Injury | Coronavirus Disease 2019 (COVID-19)

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults (ENSEMBLE 2)

Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19

United States, United Kingdom, Belgium, Spain, France, Germany, Philippines, Brazil, Colombia, South Africa
Dompé Farmaceutici S.p.A

Recruiting

Reparixin add-on Therapy to Std Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia

Severe COVID-19 | Infectious Pneumonia

United States, Australia, Turkey, Argentina, Germany, Austria, Italy
BioNTech SE
Pfizer

Recruiting

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2 | SARS-CoV-2 Virus

United States, Brazil, Puerto Rico
aTyr Pharma, Inc.

Completed

Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19

SARS-CoV-2 (COVID-19) Severe Pneumonia

United States, Puerto Rico
Synairgen Research Ltd.

Completed

Study to Assess Efficacy and Safety of Inhaled Interferon-β Therapy for COVID-19 (SPRINTER)

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2

United Kingdom, Italy, United States, Portugal, Israel, Germany, Belgium, India, Spain, Netherlands, Argentina, Brazil, Colombia, France, Mexico, Romania, Serbia
Apellis Pharmaceuticals, Inc.

Completed

A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19

Severe Acute Respiratory Syndrome | Coronavirus Infection | Covid-19 | COVID | Acute Respiratory Distress Syndrome | Coronavirus | Ards | Severe Acute Respiratory Syndrome Coronavirus 2 | Sars-CoV2

United States, Brazil
Rutgers, The State University of New Jersey
SynaVir

Terminated

A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19 (TriACT)

Covid19 | SARS-CoV Infection

United States
University of Rochester

Completed

Ultrasound Measurement of Reactive Hyperemia in Critical Care (URHC)

Critical Illness | Severe Sepsis

United States
Ophirex, Inc.
Premier Research Group plc

Terminated

Study of Varespladib in Patients Hospitalized With Severe COVID-19 (STAIRS)

Coronavirus Disease 2019 | Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants (ENSEMBLE)

Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19 at Different Stages of the Protocol

United States, Mexico, South Africa, Brazil, Chile, Colombia, Peru, Argentina
Rutgers, The State University of New Jersey
University Hospital - Newark, NJ

No longer available

Investigational COVID-19 Convalescent Plasma Infusion for Severely or Life-threateningly Ill COVID-19 Patients

COVID-19 | SARS-CoV 2 | SARS-CoV Infection

United States
AstraZeneca

Completed

Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients. (ASCENT COPD)

Chronic Obstructive Pulmonary Disease | COPD | Moderate to Very Severe COPD

United States, Canada
AstraZeneca
MedImmune LLC

Completed

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History (TERRANOVA)

Moderate to Very Severe Chronic Obstructive Pulmonary Disease

United States, Denmark, France, Sweden, Thailand, Vietnam, Belgium, Brazil, Peru, Philippines, Turkey, Taiwan, Argentina, Australia, Israel, Poland, Ukraine, Slovenia, Serbia, Mexico, Bulgaria, Colombia, New Zealand, Chile, Norway, Croatia
Partner Therapeutics, Inc.
United States Department of Defense

Completed

Sargramostim Use in COVID-19 to Recover Patient Health (SCOPE)

Covid19 | SARS-CoV Infection

United States, Argentina
Novavax

Completed

Evaluation of the Safety and Immunogenicity of Influenza and COVID-19 Combination Vaccine

Covid19 | SARS-CoV Infection

Australia
University of Oxford
Bill and Melinda Gates Foundation; Department for International Development... and other collaborators

Recruiting

Randomised Evaluation of COVID-19 Therapy (RECOVERY)

Severe Acute Respiratory Syndrome

Ghana, Indonesia, Nepal, South Africa, United Kingdom, Vietnam, India
GlaxoSmithKline

Completed

Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease (OSCAR)

Severe Acute Respiratory Syndrome

United States, Russian Federation, Peru, Netherlands, Spain, South Africa, United Kingdom, Argentina, Brazil, France, Canada, Mexico, Poland, Belgium, India, Japan, Chile, Colombia, Italy
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

rTMS in Promoting Smoking Cessation and Preventing Relapse in Current Smokers

Current Smoker | Current Every Day Smoker | Cigarette Smoker

United States
AstraZeneca
MedImmune LLC

Completed

Benralizumab Efficacy in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History (GALATHEA)

Moderate to Very Severe Chronic Obstructive Pulmonary Disease

United States, Canada, Germany, Italy, Netherlands, Spain, United Kingdom, Poland, Japan, Austria, Korea, Republic of, Russian Federation, South Africa, Czechia, Hungary, Romania, Switzerland
Institut Pasteur
Institut Pasteur de Nouvelle-Calédonie; Centre Hospitalier Territorial de Nouvelle-Calédonie and other collaborators

Completed

Household Transmission Investigation Study for COVID-19 in Tropical Regions (EPI-COVID-19)

Severe Acute Respiratory Syndrome | Coronavirus Infections | SARS-CoV Infection

French Guiana, Guadeloupe, New Caledonia
Novavax
Department of Health and Human Services

Completed

A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2

Covid19 | SARS-CoV Infection

United States, Mexico, Puerto Rico
Yale University
National Center for Advancing Translational Sciences (NCATS); Academic Pediatric...

Completed

Implementing and Evaluating a Social-Emotional Learning Program for Refugee Children During the COVID-19 Pandemic

Social Emotional Wellness

United States
Natural Cycles

Completed

NC Thermometer (Gen 3) ISO 80601-2-56 Validation

Healthy | Fever | Febrile Illness

United States
Celularity Incorporated
Lung Biotechnology PBC; California Institute for Regenerative Medicine (CIRM); ID...

Active, not recruiting

Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 (CYNKCOVID)

Coronaviridae Infections | Nidovirales Infections | RNA Virus Infections | Respiratory Tract Infections | Coronavirus Infection | Pneumonia, Viral | Pneumonia | Lung Diseases | ARDS | Coronavirus | Severe Acute Respiratory Syndrome Coronavirus 2 | Respiratory Tract Disease | Virus Disease | Physiological Effects of... and other conditions

United States
Mesoblast International Sàrl

No longer available

Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19 Infection

Moderate to Severe Acute Respiratory Distress Syndrome Associated With COVID-19

United States
Murdoch Childrens Research Institute
Bill and Melinda Gates Foundation; Royal Children's Hospital

Completed

BCG Vaccination to Protect Healthcare Workers Against COVID-19 (BRACE)

COVID-19 | Corona Virus Infection | Coronavirus Disease 2019 (COVID-19) | Respiratory Illness

Australia, Brazil, Netherlands, Spain, United Kingdom
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Outcomes Related to COVID-19 Treated With Hydroxychloroquine Among In-patients With Symptomatic Disease (ORCHID)

SARS-CoV Infection | Coronavirus | Acute Respiratory Infection

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); University of Minnesota

Completed

Effects of Filter Ventilation on Sensory Response, Smoking Topography, and Inhalation in Current Every Day Cigarette Smokers

Current Every Day Smoker | Cigarette Smoker

United States
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Completed

COVID19 SARS Vaccinations: Systemic Allergic Reactions to SARS-CoV-2 Vaccinations (SARS)

COVID-19 | SARS-CoV Infection | Allergic Reaction | Mast Cell Disorder

United States
Romark Laboratories L.C.

Completed

Trial to Evaluate the Efficacy and Safety of Nitazoxanide (NTZ) for Pre- and Post Exposure Prophylaxis of COVID-19 and Other Viral Respiratory Illnesses (VRI) in Healthcare Workers and Others at Increased Risk of SARS-CoV-2 Infection

COVID-19 | Viral Respiratory Illnesses

United States
Spectral Diagnostics (US) Inc.

No longer available

Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19

Septic Shock | Endotoxemia | COVID | Corona Virus Infection | Sepsis, Severe

United States
Alexion Pharmaceuticals

Terminated

Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia

Pneumonia, Viral | Acute Respiratory Distress Syndrome | Acute Lung Injury | COVID-19 Severe Pneumonia

United States, Spain, United Kingdom, France, Japan
The Cooper Health System
Won Sook Chung Foundation

Completed

Vitamin D3 Supplementation to Prevent Respiratory Tract Infections

Respiratory Tract Infections | Covid19 | Flu Like Illness

United States
Australian and New Zealand Intensive Care Research...
The Alfred

Completed

Recovery of Patients From COVID-19 After Critical Illness

COVID-19 | Critical Illness

Australia
Denver Health and Hospital Authority
University of Colorado, Denver; University of Miami; Beth Israel Deaconess Medical... and other collaborators

Completed

Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection

Severe Acute Respiratory Syndrome | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
HealthMode Inc.

Completed

Audio Data Collection for Identification and Classification of Coughing

Coronavirus Infections | Respiratory Tract Infections | COVID-19 | Healthy | Chronic Obstructive Pulmonary Disease | Asthma | Influenza | Common Cold | Hay Fever

United States
Roswell Park Cancer Institute

Active, not recruiting

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Acute Myeloid Leukemia | Polycythemia Vera | Myelofibrosis | Chronic Myelomonocytic Leukemia | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Secondary Acute Myeloid Leukemia | Sickle Cell Disease | Myelodysplastic Syndrome | Plasma Cell Myeloma | Chronic Granulomatous... and other conditions

United States
Roswell Park Cancer Institute

Completed

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditions

United States

Clinical Trials on Severe/Very Severe COVID-19 Illness in New Zealand

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mongolia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations