Clinical Trials on Severe Acute Respiratory Distress Syndrome in Ireland

Total 204 results

Belfast Health and Social Care Trust
Queen's University, Belfast; NHS Blood and Transplant; Northern Ireland Clinical...

Recruiting

Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) (REALIST)

Acute Respiratory Distress Syndrome

United Kingdom
Veru Inc.

Completed

COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111

Respiratory Distress Syndrome, Adult

United States
Queen's University, Belfast
Innovate UK; Northern Ireland Clinical Trials Unit

Active, not recruiting

Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome (PHIND)

Acute Respiratory Distress Syndrome (ARDS)

United Kingdom, Ireland
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome

ARDS, Human | Mechanical Ventilation | Lung Ultrasound

Denmark, Italy, Netherlands, Belgium, Greece, Ireland, Poland
Academisch Medisch Centrum - Universiteit van Amsterdam...
University of Sao Paulo; National University of Ireland, Galway, Ireland; Carlos...

Active, not recruiting

PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia (PRoVENT-COP)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Mechanical Ventilation Complication

Netherlands, Argentina, Brazil, Ireland, Spain
NeuroActiva, Inc.
Biomed Industries, Inc.

Recruiting

NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection (NATADEX)

Coronavirus Infection | Severe Acute Respiratory Syndrome Coronavirus 2 | Severe Acute Respiratory Infection

United States
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Australian and New Zealand Intensive Care Research...

Terminated

A Multi-centre Trial of an Open Lung Strategy Including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in Patients With Acute Respiratory Distress Syndrome (PHARLAP)

Acute Respiratory Distress Syndrome

Australia, Ireland, United Kingdom, New Zealand, Saudi Arabia
Cardiovascular Research Institute Dublin

Active, not recruiting

Study of HEarT DiseAse and ImmuNiTy After COVID-19 in Ireland (SETANTA)

Covid19 | Cardiomyopathies | SARS-CoV Infection

Ireland
University College Dublin

Completed

Routine Or Selective Application of a Face Mask for Preterm Infants at Birth: the ROSA Trial (ROSA)

Infant, Premature, Diseases | Respiratory Distress Syndrome, Newborn | Resuscitation | Positive-Pressure Respiration | Continuous Positive Airway Pressure

Ireland
University College Hospital Galway

Recruiting

Nebulised Heparin to Reduce COVID-19 Induced Acute Lung Injury (CHARTER-Irl)

Covid19 | ARDS, Human | Ventilation Perfusion Mismatch | Lung Injury, Acute

Ireland
BioNTech SE
Pfizer

Recruiting

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2 | SARS-CoV-2 Virus

United States, South Africa, Brazil, Puerto Rico
Eli Lilly and Company

Completed

A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury

Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States, Belgium, Spain, Canada, Australia, New Zealand
Rachael Cusack
Grifols Biologicals, LLC

Recruiting

Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock

Sepsis | Septic Shock | Sepsis, Severe

Ireland
Royal College of Surgeons, Ireland
University College Dublin; Connolly Hospital Blanchardstown

Completed

A 2 Week, Crossover Trial of Dietary Nitrate in Obstructive Sleep Apnoea Syndrome (OSAS).

Obstructive Sleep Apnoea Syndrome

Ireland
University College Hospital Galway

Terminated

Awake Prone Positioning to Reduce Invasive VEntilation in COVID-19 Induced Acute Respiratory failurE (APPROVE-CARE)

COVID19 | Mechanical Ventilation Complication | ARDS, Human

Ireland
University College Cork

Not yet recruiting

Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography (DiFuSE)

Gestational Diabetes | Neonatal Encephalopathy | Diastolic Dysfunction | Trisomy 21 | Transient Tachypnea of the Newborn | Small for Gestational Age at Delivery

Ireland
Draeger Medical Systems, Inc.

Unknown

Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates

Respiratory Distress Syndrome In Premature Infants

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Decitabine Followed by Mitoxantrone Hydrochloride, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia

United States
Windtree Therapeutics

Completed

The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational Age

Respiratory Distress Syndrome

United States, Canada, Colombia, Hungary, Chile, Ireland, Netherlands, Poland
Women and Infants Hospital of Rhode Island

Unknown

CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure (NICA)

Respiratory Distress Syndrome | Apnea of Prematurity | Prematurity

United States
University of Alberta
University of Manitoba; University of British Columbia; McGill University; McMaster... and other collaborators

Recruiting

30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants (HiLo)

Premature Infant | Respiratory Distress Syndrome in Premature Infant | Neurodevelopmental Outcome

Canada, Ireland, Spain
University College Dublin
Mater Misericordiae University Hospital; Irish Cancer Society

Recruiting

COMpassion FOcused Therapy and Breathing Pattern REtraining After Cancer Recurrence (COMFORT)

Psychological Distress | Cancer Recurrence

Ireland
Partner Therapeutics, Inc.
United States Department of Defense

Completed

Sargramostim Use in COVID-19 to Recover Patient Health (SCOPE)

Covid19 | SARS-CoV Infection

United States, Argentina
Novavax
Department of Health and Human Services

Completed

A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2

Covid19 | SARS-CoV Infection

United States, Mexico, Puerto Rico
Veru Inc.

Completed

VERU-111 in the Treatment of SARS-Cov-2 Infection by Assessing Its Effect on the Proportion of Patients Who Die on Study (VERU-111)

SARS-CoV Infection

United States, Argentina, Brazil, Bulgaria, Colombia, Mexico
St Vincent's University Hospital, Ireland
ResMed

Suspended

Adaptive Servo Ventilation (ASV) in Heart Failure

Acute Decompensated Heart Failure | Sleep Disordered Breathing

Ireland
University of Washington
National Cancer Institute (NCI)

Completed

Outpatient Induction Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome

Adult Acute Myeloid Leukemia | Adult Myelodysplastic Syndrome

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants (Surfactant 2)

Respiratory Insufficiency | Respiratory Distress Syndrome | Infant, Newborn

United States
Windtree Therapeutics

Terminated

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA

Respiratory Distress Syndrome

Canada, United States, Chile, Poland
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure (Preemie iNO)

Pneumonia | Sepsis | Hypertension, Pulmonary | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn | Respiratory Distress Syndrome (RDS)

United States
Rhode Island Hospital

Recruiting

Assessment for Implementation Methods in Sepsis (AIMS)

Septic Shock | Sepsis Severe

United States
Royal Liverpool University Hospital

Completed

Psychological Impact of COVID-19 on Intensive Care Survivors (PIM-COVID)

Depression | COVID-19 | Anxiety | Psychological Distress | Post-traumatic Stress Disorder | Post Intensive Care Syndrome

United Kingdom
The Miriam Hospital

Recruiting

De-resuscitation Informed by Ultrasound for Patients With Sepsis (DRI-US)

Sepsis | Septic Shock | Sepsis, Severe | Volume Overload

United States
University College Dublin
National Children's Research Centre; Our Lady's Children's Hospital, Crumlin

Completed

Single Dose Oral Dexamethasone Versus Multi-dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in Children

Asthma | Acute Asthma

Ireland
ARC Devices
Cork University Hospital

Completed

Comparison of a Novel Non-Invasive, Non-Touch Infrared Thermometer With Routine Thermometry in Routine Clinical Practice

Healthy | Febrile

Ireland
NICHD Neonatal Research Network
Canadian Institutes of Health Research (CIHR); National Center for Research... and other collaborators

Terminated

Early Inhaled Nitric Oxide for Respiratory Failure in Newborns (Early iNO)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
Meditrix Corp
National University of Ireland, Galway, Ireland; Boston Scientific Japan K.K.; Fujita Health University

Recruiting

Acetyl Salicylic Elimination Trial JAPAN: The ASET JAPAN Pilot Study (ASET-JAPAN)

Chronic Coronary Syndrome | Non ST Segment Elevation Acute Coronary Syndrome

Japan, Ireland
Rhode Island Hospital

Completed

Restrictive Intravenous Fluids Trial in Sepsis (RIFTS)

Septic Shock | Severe Sepsis

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Terminated

Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)

Respiratory Insufficiency | Pulmonary Hypertension | Respiratory Distress Syndrome, Newborn | Prematurity

United States
Belfast Health and Social Care Trust
Hoffmann-La Roche; Medical Research Council; Aerocrine AB

Completed

A Pragmatic Trial of Corticosteroid Optimisation in Severe Asthma

Severe Persistent Asthma

United Kingdom
Northwell Health
Staten Island University Hospital

Completed

The Use of Heliox in Obstructive Sleep Apnea Syndrome (HOSA)

Obstructive Sleep Apnea Syndrome

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR); Medical Research Council of...

Terminated

Inhaled Nitric Oxide Study for Respiratory Failure in Newborns (NINOS)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States, Canada
Beaumont Hospital
Aerogen

Completed

Effectiveness of Vibrating Mesh Versus Small Volume Nebuliser in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease | COPD | COPD Exacerbation | Copd Exacerbation Acute

Ireland
University of Turku
Finnish Foundation for Cardiovascular Research

Unknown

CRAGS (Coronary aRtery diseAse in younG adultS) (CRAGS)

Coronary Artery Disease | Percutaneous Coronary Intervention | Coronary Artery Bypass Grafting | Acute Coronary Syndromes | Young Patient

Finland, Italy, Iceland, Sweden
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial (ALPS)

Pregnancy | Preterm Birth | Respiratory Distress Syndrome | Pregnancy Outcomes

United States
Rhode Island Hospital
Brown University

Not yet recruiting

Long COVID-19 Intervention Using Digital Health & Technology (LIGHT)

Long COVID | Distress Tolerance

United States
PureTech

Recruiting

A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

MDS | AML, Adult Recurrent

United States
University of Milano Bicocca

Recruiting

Respiratory Mechanics Assessment During Assisted Mechanical Ventilation (ICEBERG)

Acute Hypoxemic Respiratory Failure

Spain, Canada, Germany, Ireland, Italy
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

The Budesonide in Babies (BiB) Trial (BiB)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia (BPD) | Prematurity; Extreme | Neonatal

United States

Clinical Trials on Severe Acute Respiratory Distress Syndrome in Ireland

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