Clinical Trials on Severe Aortic Valve Disease

Total 7165 results

Beth Israel Deaconess Medical Center

Recruiting

Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System (TAVR-HBE)

Aortic Stenosis | Heart Block | Transcatheter Aortic Valve Replacement

United States
Jung-min Ahn

Recruiting

Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement (RENOVATE)

Thromboembolism | AORTIC VALVE DISEASES

Korea, Republic of
Population Health Research Institute
Sunnybrook Health Sciences Centre; Hamilton Health Sciences Corporation; Southlake... and other collaborators

Active, not recruiting

Remote ECG Monitoring of TAVI Patients

Aortic Valve Stenosis | Cardiac Valve Disease

Canada
Karolinska University Hospital
Karolinska Institutet

Completed

Valve Leaflet Motion in Sutureless Bioprosthetic Aortic Valves

Aortic Valve Stenosis | Heart Valve Disease

Sweden
University Hospital Inselspital, Berne

Terminated

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage (TAVI-LAAC)

Aortic Valve Disorder

Switzerland, Italy, Germany, Portugal
Instituto Nacional de Cardiologia Ignacio Chavez

Completed

Evaluation of the Inflammatory Response in Post-operated Aortic Valve Replacement Patients.

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Calcification | Prosthetic Valve Malfunction

Mexico
Dokuz Eylul University

Completed

The Effect of Education and Follow-up Program in Patients Undergoing TAVI

Aortic Stenosis | Nursing Caries

Turkey
Avicena LLC

Withdrawn

Rapid Non-invasive Detection of Aortic Stenosis

Aortic Valve Disease | Heart Valve Diseases | Heart Murmurs

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0) (TAILOR-TAVR)

Aortic Stenosis With Bicuspid Valve

China
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Nanchang University; Chinese PLA General Hospital and other collaborators

Recruiting

HANGZHOU Solution in Bicuspid AS Undergoing TAVR

Aortic Stenosis | Aortic Stenosis With Bicuspid Valve

China
Instituto Nacional de Cardiologia Ignacio Chavez

Completed

Analysis and Comparative Evaluation of Aortic Calcium by Computed Tomography and Histopathology in Patients With Aortic Stenosis

Aortic Valve Stenosis | Aortic Calcification Valve

Mexico
Rhode Island Hospital

Recruiting

Assessment of Clinical Onset of IV Heparin in Interventional Cardiology and Cardiac Surgery (ACTPOC)

Transcatheter Aortic Valve Replacement | Cardiac Valve Annuloplasty

United States
Baystate Medical Center
Springfield College

Completed

Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study

Coronary Artery Disease | Aortic Valve Stenosis | Mitral Valve Insufficiency | Mitral Valve Stenosis | Aortic Valve Regurgitation | Coronary Artery Bypass Graft Triple Vessel

United States
University Medical Centre Ljubljana

Not yet recruiting

Conventional Versus Left Bundle Branch Pacing in TAVI

Heart Failure | Aortic Valve Stenosis | Pacemaker-Induced Cardiomyopathy | Transcatheter Aortic Valve Implantation

Slovenia
Edwards Lifesciences

Completed

Surgical Treatment of Aortic Stenosis With a Next Generation Surgical Aortic Valve (TRITON)

Aortic Valve Stenosis | Aortic Valve Stenosis With Insufficiency

Austria, Germany
Romanian Society of Cardiology

Recruiting

Romanian National Registry of Outcomes After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis - RO-TAVI (RO-TAVI)

Aortic Valve Stenosis | Aortic Stenosis Symptomatic

Romania
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03) (2011-03)

Aortic Stenosis Symptomatic

Germany, Brazil
Abbott Medical Devices

Completed

First in Human Experience of the St. Jude Medical TAVI Valve and Delivery System (SJM TAVI FIH)

Symptomatic Aortic Stenosis

United Kingdom
Abbott Medical Devices

Completed

Portico TAVI Implant With Transfemoral Delivery System

Symptomatic Aortic Stenosis

United Kingdom, Germany, Netherlands, Denmark, Australia
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort

Symptomatic Aortic Stenosis

Germany, Japan, Brazil
Symetis SA

Completed

Feasibility Trial on ACURATE™ Transapical Implantation in Patients With Severe Symptomatic Aortic Stenosis (2009-01) (TA-FIM)

Aortic Stenosis Symptomatic

Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...
Edwards Lifesciences

Unknown

Feasibility of Continuous Noninvasive Finger Arterial Blood Pressure Measurement for Detection and Staging of Aortic Stenosis (COaRt)

Aortic Stenosis, Calcific

Netherlands
Jian'an Wang,MD,PhD

Not yet recruiting

Sizing-sTrategy of Bicuspid AoRtic Valve Stenosis With Transcatheter Self-expandable Valve (START)

Aortic Valve Stenosis

China
Edwards Lifesciences
Rundo International Pharmaceutical Research & Development Co.,Ltd.; Edwards... and other collaborators

Active, not recruiting

INSPIRIS China PMCF Study (INSPIRIS China)

Aortic Valve Replacement

China
Edwards Lifesciences

Suspended

INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study (INVIVITY)

Aortic Valve Replacement

United States
St. Antonius Hospital

Completed

Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement (LIAR)

Quality of Life | Aortic Valve Stenosis | Limited Access Aortic Valve Replacement

Netherlands
Erasmus Medical Center

Recruiting

Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort II: Structural Heart Interventions (PLUTO-II) (PLUTO-II)

Heart Failure | Aortic Stenosis | Valvular Heart Disease | Mitral Insufficiency | Tricuspid Insufficiency

Netherlands
REDNVIA Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)

Calcific Aortic Valve Disease

United States
University of Bari

Unknown

Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery (ATIII)

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Acute Coronary Syndrome | Mitral Valve Stenosis

Italy
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of HS-10511 in Healthy Subjects

Hypertrophic Cardiomyopathy
NYU Langone Health

Enrolling by invitation

OPIE in the Thin Interventricular Septum

Hypertrophic Cardiomyopathy

United States
University of Pittsburgh

Terminated

Genetic Predictors of Outcome in HCM Patients

Hypertrophic Cardiomyopathy

United States
Oregon Health and Science University

Unknown

Perfusion Imaging With Myocardial Contrast Echocardiography in HCM

Hypertrophic Cardiomyopathy

United States
Insel Gruppe AG, University Hospital Bern

Recruiting

Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement (Co-STAR)

Transcatheter Aortic Valve Replacement | Atrial Fibrillation New Onset | Pacemaker | Colchicine

Switzerland
Samsung Medical Center

Recruiting

Open Label RCT for Chronic Severe AR : Entresto vs. CCB/ARB (REVERSE-AR)

Aortic Valve Insufficiency

Korea, Republic of
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, Switzerland, France, Italy, Germany, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
University of Turku
Helsinki University Central Hospital; Kuopio University Hospital; St. Antonius... and other collaborators

Recruiting

Left Atrial Appendage CLOSURE for the Prevention of Thromboembolisms in Patients Undergoing Aortic Bioprosthesis Surgery (LAA-CLOSURE)

Aortic Stenosis

Finland, Netherlands
University Hospital, Caen

Completed

Femoral vs Radial Approach and MRI Evaluation of Strokes

Aortic Stenosis

France
Hospital Universitari Vall d'Hebron Research Institute

Completed

Evaluating the Effectiveness of Atorvastatin on the Progression of Aortic Dilatation and Valvular Degeneration in Patients With Bicuspid Aortic Valve (BICATOR)

Bicuspid Aortic Valve

Spain
Rigshospitalet, Denmark
Odense University Hospital; Sahlgrenska University Hospital, Sweden; Danish Heart... and other collaborators

Active, not recruiting

The Nordic Aortic Valve Intervention Trial (NOTION)

Critical Aortic Stenosis

Denmark, Sweden
Shared Decision Making Resources
Edwards Lifesciences

Completed

Understanding Patient Goals and Preferences to Facilitate Shared Decision Making for Symptomatic Aortic Stenosis

Aortic Stenosis Symptomatic

United States
Medtronic Bakken Research Center

Completed

ADVANCE Direct Aortic Study

Aortic Stenosis | Valvular Heart Disease

Netherlands, United Kingdom, Czechia, France, Germany, Italy
Edwards Lifesciences

Terminated

RESILIENCE Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Under 65 (RESILIENCE)

Aortic Valve Replacement

United States
Maria Cecilia Hospital
Ettore Sansavini Health Science Foundation

Completed

Minimally Invasive Versus Conventional Aortic Valve Replacement: a Long Term Registry (SATURNO)

Aortic Valve Surgery

Italy
Cardiawave SA

Completed

A Prospective RegistrY of Cardiac Echographic Loops (ARYEL)

Calcified Aortic Valve

France
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Use of the SonoSite Probe for Measuring Jugular Venous Pressure (PRAGUE)

Aortic Valve Surgery

United Kingdom
CardioGard Medical Ltd.

Completed

Safety and Performance Study of the CardioGard Cannula

Aortic Valve Replacement

Israel, Switzerland, Germany
Shanghai MicroPort Medical (Group) Co., Ltd.

Unknown

Safety and Efficacy Study of MicroPort's Transcatheter Aortic Valve and Delivery System for TAVI

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Calcification

China
Medtronic Cardiovascular

Active, not recruiting

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

Bicuspid Aortic Valve

United States
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Structural Heart and Valve Network PROSPECTIVE Registry

Heart Failure | Aortic Valve Stenosis | Mitral Valve Regurgitation | Heart Valve Disease | Tricuspid Valve Regurgitation

United States

Clinical Trials on Severe Aortic Valve Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Myanmar

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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