Clinical Trials on Severe Obesity

Total 13645 results

National Institute of Allergy and Infectious Diseases...

Completed

Phase I Trial of Measles Vectored Chikungungya Vaccine

Chikungunya Virus Infection

United States
Northwestern University
Gaymar Industries, Inc.

Completed

Temperature Control in Central Fever in the Neuro-ICU

Fever | Brain Hemorrhage

United States
Rovere Querini Patrizia
ASST Fatebenefratelli Sacco; ASST Grande Ospedale Metropolitano Niguarda

Recruiting

Primary Care-Hospital Embedding: a Prospective, Multicentric, Observational Study (PRIME)

Heart Failure | Pneumonia | Hypertension | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Urinary Tract Infections | Deep Vein Thrombosis | Fever of Unknown Origin

Italy
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
University Hospital, Angers

Recruiting

Clusterin, Ptx3 and Pediatric Febrile Neutropenia (CluPPFeN) (CluPPFeN)

Febrile Neutropenia | Cancer Childhood

France
Yonsei University

Completed

Micafungin Versus Intravenous Itraconazole as Empirical Antifungal Therapy for Febrile Neutropenic Patients With Hematological Diseases

Febrile Neutropenia | Hematological Diseases

Korea, Republic of
Kjeld Schmiegelow

Recruiting

Early Termination of Empirical Antibiotics in Febrile Neutropenia in Children With Cancer

Pediatric Cancer | Neutropenia, Febrile

Denmark
Radboud University Medical Center
Canisius-Wilhelmina Hospital

Unknown

Multisystem Features of Malignant Hyperthermia or Rhabdomyolysis Related to RYR1 Variants

Malignant Hyperthermia | Rhabdomyolysis | RYR1 Variant

Netherlands
M.D. Anderson Cancer Center

Completed

Laparoscopic Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) for Metastatic Gastric Cancer

Gastrointestinal Cancer

United States
Coherus Biosciences, Inc.
Community Clinical Oncology Research Network, LLC

Unknown

An Analysis to Estimate Febrile Neutropenia (FN) in Patients Receiving Udenyca (POEM)

Febrile Neutropenia | Non-myeloid Malignancy

United States
Cedars-Sinai Medical Center

Completed

Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery

Fever | Hypothermia | Orthostatic Hypotension | Hemodynamic Instability

United States
Yuhan Corporation

Completed

Phase I Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of YHB1411-2 in Healthy Male Volunteers

Rheumatic Arthritis

Korea, Republic of
University Hospital, Strasbourg, France

Recruiting

Study of Febrile Syndromes After Tick Bite (FebriTick)

Febrile Syndrome

France
Chang Gung Memorial Hospital

Recruiting

Risk of Acute Kidney Injury in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy

Acute Kidney Injury

Taiwan
University Hospital, Lille
Ministry of Health, France

Recruiting

DIStinguishing ChildrEn at Low Risk of Severe infectioN in Case of Febrile Neutropenia-7: Impact Study of a Clinical Decision Rule (DISCERN-FN7)

Neutropenia, Febrile

France
Jost Langhorst

Completed

Hyperthermia in Fibromyalgia Syndrome (HYPAIN)

Fibromyalgia

Germany
Hospital Infantil de Mexico Federico Gomez
Hospital Juarez de Mexico; Instituto Nacional de Pediatria

Completed

Safety and Efficacy of Ambulatory Versus In-hospital Antibiotic Treatment in Children With Febrile Neutropenia

Chemotherapy-Induced Febrile Neutropenia
All India Institute of Medical Sciences, New Delhi

Terminated

Early Stoppage Versus Continuation of Antimicrobial Therapy in Low Risk Pediatric Cancer Patients With Febrile Neutropenia, Before Recovery of Counts: -DALFEN Study (DALFEN)

Pediatric Cancer | Neutropenia, Febrile

India
M.D. Anderson Cancer Center

Completed

Quality of Life Study for Pediatric and Adult Patients Undergoing Hyperthermic Peritoneal Perfusion With Cisplatin

Peritoneal Neoplasms

United States
Assistance Publique - Hôpitaux de Paris

Completed

Assessment of New Blood Culture Methods on the Microbiological Documentation of Febrile Neutropenia (HEMATOCPLUS)

Neutropenia | Febrile | Post-chemotherapy

France
Amgen

Completed

Same Day Dosing of Pegfilgrastim in Breast Cancer Patients Undergoing Chemotherapy (TAC)

Breast Cancer | Neutropenia | Fever
Forschungsinstitut für Balneologie und Kurortwissenschaft...

Completed

Mild Water-Filtered Near Infrared Whole-Body-Hyperthermia as an Adjunct in the Treatment of Fibromyalgia

Fibromyalgia

Germany
Columbia University
University of California, Berkeley

Recruiting

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin Resistance | Prediabetic State | Overweight and Obesity | Non-Alcoholic Fatty Liver Disease

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
National Research Council

Recruiting

Using Tissue-based Spatial Data to Understand How Obesity-related Tumor Metabolites Fuel Prostate Cancer Progression (OBESITA'&PCa)

Obesity | Prostate Cancer | Prostate Adenocarcinoma | Prostate Neoplasm | Prostatic Neoplasm

Italy
Ondokuz Mayıs University

Not yet recruiting

The Effect of Incontinence Program Applied to Obese Elderly on Quality of Life, Coping and Loneliness

Aging | Incontinence, Urge | Incontinence Stress | Obesity, Primary

Turkey
Western University

Not yet recruiting

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

Obesity | Diabetes | Metabolic Syndrome | Bone Diseases | Hyperlipidemias | Prostate Cancer | Cardiovascular Morbidity
Brigham and Women's Hospital
Boston Scientific Corporation; American Society for Gastrointestinal Endoscopy

Recruiting

A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)

Obesity | Non-alcoholic Fatty Liver Disease (NAFLD) | Liver Function | Non-alcoholic Steatohepatitis (NASH) | Liver Fibroses | Endoscopic Ultrasound | Endoscopic Sleeve Gastroplasty

United States
Xijing Hospital

Recruiting

Optimized Cardioprotection Therapy in Obese Subjects With CAD

Obesity | Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)) | Adiposis; Heart

China
National Institute of Diabetes and Digestive and...

Recruiting

Molecular and Clinical Profile of Diabetes Mellitus and Its Complications

Obesity | Diabetes Mellitus, Type 2 | Diabetic Nephropathy

United States
Hoskinson Health and Wellness Clinic
University of Wyoming; Buck Institute for Research on Aging

Active, not recruiting

Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity

Depression | Cardiovascular Diseases | Inflammation | Hypertension | Obesity | Cognitive Impairment | Insulin Resistance | Hyperlipidemias | Physical Disability | Physical Inactivity | Hormone Deficiency | Overeating

United States
Saniona

Completed

Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS) (2016-003694-18)

Confirmed Genetic Diagnosis of Prader-Willi Syndrome

Czechia, Hungary
Weill Medical College of Cornell University
National Institutes of Health (NIH); PWSAUSA

Terminated

Effect of Rimonabant on Weight Gain and Body Composition in Adults With Prader Willi Syndrome (PWS)

Prader-willi Syndrome

United States
Vastra Gotaland Region

Enrolling by invitation

GOTHA - The Early Arthritis and Psoriasis Study of Region Västra Götaland, Sweden (GOTHA)

Cardiovascular Diseases | Lung Diseases | Obesity | Arthritis | Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis

Sweden
Suzanne Morin
CHU de Quebec-Universite Laval

Completed

Determinants of Bone and Muscle Quality and Strength in Obesity With and Without Diabetes (BODI2)

Quality of Life | Obesity | Fractures, Bone | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Body Weight | Musculoskeletal Diseases | Osteoporosis | Bone Diseases, Metabolic | Fall | Osteoporotic Fractures

Canada
Woman's
Novo Nordisk A/S

Completed

Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS (SAXAPCOS)

Polycystic Ovary Syndrome | Pre Diabetes | Obesity Android

United States
Goethe University
King's College London; Radboud University Medical Center; Heidelberg University; Hospital Vall d'Hebron

Completed

Prevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder (PROUD)

Depression | Obesity | Attention-Deficit / Hyperactivity Disorder

Germany, Netherlands, Spain, United Kingdom
NYU Langone Health
Winthrop University Hospital

Withdrawn

Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Unknown

Autonomic Regulation in Prader-Willi Syndrome

Autonomic Dysfunction

Taiwan
Towson University
Pulmonary Critical Care Associates of Baltimore

Completed

Sleep Apnea, Cardiovascular and Exercise Study

Vascular Diseases | Obesity | Obstructive Sleep Apnea

United States
Hossam Kandil

Terminated

Increasing Cure Rate of Hepatitis C Therapy in Obese Hepatitis C Patients

Obesity | Hepatitis C | Metabolic Syndrome | Insulin Resistance

United States
University of Oulu
Oulu University Hospital; Juho Vainio Foundation; Yrjo Jahnsson Foundation

Completed

The Effect of CBT- Based Weight Loss Program on Obesity (CognObe)

Obesity | Diabetes Mellitus, Type 2 | Anhedonia | Hypercholesterolemia

Finland
Novo Nordisk A/S

Completed

Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ - Sleep Apnoea

Obesity | Metabolism and Nutrition Disorder | Obstructive Sleep Apnoea

United States, Canada
University of Aarhus

Completed

Obstructive Sleep Apnea-induced Changes in Adipose and Liver Tissue and Effects of Massive Weight Loss on Inflammation

Obesity | Obstructive Sleep Apnea

Denmark
University of Sao Paulo

Completed

Gestational Diabetes Mellitus, Obesity and Periodontal Disease

Obesity | Periodontal Diseases | Diabetes Mellitus, Gestational

Brazil
Ferring Pharmaceuticals

Completed

Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States
University Hospital, Rouen

Completed

Sleep Apnea, Obesity and Pregnancy (GOS)

Obesity | Pregnancy

France
Instituto Nacional de Perinatologia Isidro Espinosa...
National Council of Science and Technology, Mexico

Completed

Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women

Pregestational Obesity (BMI > 27kg/m2) | History of Polycystic Ovary Syndrome

Mexico
University of Roma La Sapienza

Completed

Testosterone Replacement in Metabolic Syndrome and Inflammation (TERMSINFAT)

Obesity | Metabolic Syndrome | Erectile Dysfunction | Hypogonadism

Italy
University of Florida
Foundation for Prader-Willi Research

Completed

Hypoglycemia in Prader-Willi Syndrome

Hypoglycemia | Prader Willi Syndrome

United States
Arizona State University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Biomarkers of Oxidative Stress in LOOK AHEAD - Ancillary to LOOK AHEAD

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Obesity | Diabetes Mellitus | Diabetes Mellitus, Non-insulin Dependent

Clinical Trials on Severe Obesity

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