Clinical Trials on Severe Spasticity

Total 4432 results

Kessler Foundation

Not yet recruiting

"Epidural Spinal Cord Stimulation: Addressing Spasticity and Motor Function"

Spasticity
University of Castilla-La Mancha

Completed

Importance of the Current Density in TENS

Spasticity
Ipsen

Completed

Retrospective Real-Life Study From One Brazilian Reference Center Assessing Long-Term Experience In The Treatment Of Adult Spasticity With AbobotulinumtoxinA (RETURN)

Spasticity

Brazil
Acorda Therapeutics

Completed

A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial (TQT)

Spasticity

United States
Sun Pharma Advanced Research Company Limited

Completed

Efficacy and Safety of SPARC0921 in Subjects With Spasticity

Spasticity

United States, Germany, Hungary, Russian Federation, Ukraine
Sun Pharma Advanced Research Company Limited

Completed

Safety Study of SPARC1104

Spasticity

United States
University of Castilla-La Mancha

Unknown

Modulation of H-reflex After Application of Electric Currents in Healthy People

Spasticity

Spain
Vanderbilt University

Terminated

Botox vs. Baclofen for Upper Limb Spasticity

Spasticity

United States
Shirley Ryan AbilityLab
Allergan

Completed

Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity

Post-stroke Shoulder Pain and Spasticity

United States
Ohio State University
Varian Medical Systems; Centro Diagnostico Milano, Co-PI: Pantaleo Romanelli...

Recruiting

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy (SPASM)

Spasticity, Muscle | Spastic Cerebral Palsy | Spasticity as Sequela of Stroke

United States, Italy
Hospital for Special Surgery, New York

Terminated

rTMS in Treatment of Spasticity

ALS

United States
Pierre and Marie Curie University

Completed

Assessment of the Excitability of Spinal Motoneurons Using Stimulus-response Curves of the Bulbocavernosus Reflex

Spasticity, Muscle

France
Centre Hospitalier Universitaire Dijon

Completed

Study of the Reaction of the Brain to Various Stimulations

Corticospinal Plasticity | Neuromuscular Plasticity

France
Riphah International University

Recruiting

Multiphasic Neuroplasticity Based Training Protocol With Shock Wave Therapy For Post Stroke Spasticity

Stroke | Spasticity, Muscle

Pakistan
Kayseri City Hospital
Saglik Bilimleri Universitesi

Completed

Efficacy of Extracorporeal Shock Wave Therapy on Spasticity

Stroke | Spasticity, Muscle

Turkey
Novo Nordisk A/S

Completed

Activated Recombinant Human Factor VII in Patients With Dengue Haemorrhagic Fever

Acquired Bleeding Disorder | Dengue Haemorrhagic Fever

Malaysia, Philippines, Thailand
Johns Hopkins University
Saluda Medical Pty Ltd

Not yet recruiting

Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity (CLONUS)

Chronic Pain | Spasticity as Sequela of Stroke | Upper Motor Neuron Lesion

United States
National Taiwan University Hospital

Recruiting

FlexWave Trial: Efficacy of Extracorporeal Shock Wave Therapy in Post-Stroke Upper Limb Spasticity

Stroke | Spasticity, Muscle

Taiwan
Universidad de Zaragoza

Enrolling by invitation

Analysis of the Correlation Between Ultrasound and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower Limb (US-function)

Stroke | Spasticity, Muscle

Spain
Ipsen

Completed

Dysport® Adult Lower Limb Spasticity Follow-on Study

Post-stroke Spasticity | Spasticity Post-Traumatic Brain Injury

United States, Australia, France, Belgium, Hungary, Poland, Portugal, Slovakia, Czechia, Russian Federation, Italy
Istanbul Physical Medicine Rehabilitation Training...

Completed

The Effect of Inhibitory Kinesio Taping Application on Spasticity, Stretch Reflex and Motor Neuron Activity

Muscle Physiology

Turkey
Istanbul Physical Medicine Rehabilitation Training...

Completed

Optimal Interstimulus Interval For Consecutive H-Reflex Responses In Patients With Spasticity

Muscle Hypertonia | Reflex, Abnormal

Turkey
Seoul National University Hospital
Korea Institute of Science and Technology

Completed

Developing Optimal Focal Muscle Vibration for Improving Spasticity

Muscle Spasticity | Electrophysiology | Vibration

Korea, Republic of
Medical University of South Carolina
National Institute of General Medical Sciences (NIGMS)

Completed

DDN in Stroke--COBRE (CDN)

Stroke | Spasticity, Muscle | CVA

United States
University Hospital, Grenoble

Completed

Pain During Injection With Botulinum Toxin in Post-stroke Spasticity Treatment (DOLOTOX)

Post-stroke Spasticity
Istanbul Physical Medicine Rehabilitation Training...

Completed

The Effect of Whole Body Vibration (WBV) on Spasticity in Poststroke Hemiplegia (WBV)

Muscle Spasticity | Physiology

Turkey
Sun Pharma Advanced Research Company Limited

Completed

Study of SPARC1103 in Subjects With Spasticity

Spasticity

United States, Russian Federation, Ukraine
Kocaeli University

Not yet recruiting

Efficacy of Extracorporeal Shock Wave Therapy in Children With Cerebral Palsy

Cerebral Palsy | Spasticity/Paresis
Suleyman Demirel University

Not yet recruiting

The Effect of Speed-based Training on Spasticity and Balance

Stroke | Spasticity, Muscle | Balance; Distorted

Turkey
Sisli Hamidiye Etfal Training and Research Hospital

Withdrawn

The Effect of Ultrasound-Guided Botulinum Toxin Injections on Pain, Functionality, Spasticity, and Range of Motion in Patients With Post-Stroke Upper Extremity Spasticity

Cerebrovascular Disorders | Spasticity, Muscle | Botulinum Toxin
Ipsen

Completed

Study to Assess Impact of Dysport Injections Early After Stroke on Upper Limb Spasticity Progression (ONTIME Pilot)

Stroke | Upper Limb Spasticity

Malaysia, Philippines, Singapore, Thailand
Mahidol University

Completed

Perfetti Method on Upper Extremity Spasticity of Stroke Patient

Stroke Syndrome Sequela Spasticity

Thailand
GlaxoSmithKline

Completed

A Phase III Study to Evaluate the Efficacy and Safety of GSK1358820 in Subjects With Post-stroke Upper Limb Spasticity

Spasticity, Post-Stroke

Japan
Yonsei University

Unknown

Optimal Dose of Extracorporeal Shock Wave Therapy After Botulinum Toxin Type A Injection for Post-stroke Spasticity

Post-Stroke Elbow Spasticity

Korea, Republic of
Ipsen

Completed

Study to Document the Effectiveness of Dysport in Patients Suffering From Upper Limb Spasticity (ULS) After Stroke (PSAS REGISTRY)

Post Stroke Arm Spasticity

Poland
Chang Gung Memorial Hospital

Completed

Kinesiotaping Combined With Therapeutic Exercise in Upper Extremity Spasticity and Function in Subacute Stroke Patients

Stroke | Upper Extremity Spasticity
GlaxoSmithKline

Completed

A Multicenter, Open-label, Single Dose Study of the Safety and Efficacy of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Focal Upper Limb Spasticity

Spasticity, Post-Stroke

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Focal Muscular Vibration in Patients With Severe Acquired Brain Injury

Brain Injuries | Spasticity, Muscle

Italy
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Individualized rTMS Based on fNIRS to Spasticity

Stroke | Rehabilitation | Spasticity, Muscle

China
Swiss Paraplegic Centre Nottwil
Medical University of Vienna

Withdrawn

Carry-over Effects of Repetitively Applied Transcutaneous Spinal Cord Stimulation on Spasticity (SCS-CorE)

Spinal Cord Injuries | Spasticity, Muscle

Switzerland
Izmir Katip Celebi University

Completed

Assesment of Post-stroke Elbow Flexor Spasticity in Different Forearm Positions

Post-stroke Elbow Spasticity

Turkey
Acorda Therapeutics
Syneos Health

Terminated

Phase 1b Study of Tizanidine in Pediatric Patients With Cerebral Palsy

Spasticity Due to Cerebral Palsy

United States
Vancouver Island Health Authority

Recruiting

Effect of Cryoneurolysis on Pain in Patients With Hand Contracture.

Spasticity, Muscle | Contracture

Canada
Medy-Tox

Completed

CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase1)

Muscle Spasticity

Korea, Republic of
Medy-Tox

Completed

CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase3)

Muscle Spasticity

Korea, Republic of
University Hospital, Toulouse
Merz Pharmaceuticals GmbH

Completed

Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment (BacloTox)

Muscle Spasticity

France
Ipsen

Completed

Adult Subjects Suffering From Lower Limb Spasticity Following Stroke (VALGAS)

Spasticity

Spain
Ipsen

Completed

ETREAT Study on Effectiveness of Botulinum Toxin Type A Injections to Treat Post-stroke Upper and/or Lower Limb Spasticity (ETREAT)

Spasticity

Spain
Medy-Tox

Completed

MEDITOXIN® Versus BOTOX® in the Treatment of Post-stroke Spasticity of the Upper Limb Spasticity

Spasticity

Korea, Republic of
Universiteit Antwerpen
McGill University; Aragon Institute of Health Sciences

Not yet recruiting

Comparative Study of the Mechanism of Action of Dry Needling and Botulinum Toxin Type A as a Treatment for Lower Limb Post-stroke Spasticity: a Proof of Concept Controlled Trial (STROKEPOC)

Stroke | Spasticity as Sequela of Stroke

Clinical Trials on Severe Spasticity

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