Clinical Trials on Severely Obese Patients

Total 7710 results

University of Ulsan

Completed

Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis

Pneumonia | Abscess | Peritonitis | Leakage | Bowel Perforation
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma (METAKIT)

Multi-organ Failure After Severe Trauma

France
University Hospital, Basel, Switzerland
Swiss Multiple Sclerosis Registry

Recruiting

A Study to Assess the Potential Impact of Disease Modifying Therapies on COVID-19 Outcomes and the Antibody Response Following an Infection With SARS-CoV-2 in Patients With Multiple Sclerosis Within the Swiss Multiple Sclerosis Cohort. (MS COVID-19)

Multiple Sclerosis | COVID-19 (Severe Coronavirus Disease 2019)

Switzerland
SynAct Pharma Aps

Recruiting

A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe Proteinuria

Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy | Severe Proteinuria Due to Idiopathic Membranous Nephropathy

Denmark
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI) (PAROCARD)

Carotid Atherosclerosis | Acute Myocardial Infarction | Severe Periodontitis

France
Janssen Research & Development, LLC

Completed

A Study to Characterize the Clinical Course of Pregnant Women and Children at High Risk for Early Onset Severe Hemolytic Disease of the Fetus and Newborn

Erythroblastosis, Fetal | Early Onset Severe Hemolytic Disease of the Fetus and Newborn (EOS-HDFN)

United States, Canada, Netherlands, Belgium, Australia, Germany, Spain, Sweden, United Kingdom
Catherine Bollard

Active, not recruiting

Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma (ALCI2)

Hodgkin Disease | Non Hodgkin Lymphoma | Leiomyosarcoma | Lymphoepithelioma | Severe Chronic Active EBV Infection Syndrome (SCAEBV)

United States
Arrowhead Regional Medical Center

Completed

Insulin Regulation and Severity of Severe Acute Respiratory Syndrome COVID-19 Infection

COVID-19 | Diabetes Mellitus | COVID-19 Pneumonia | COVID-19 Respiratory Infection

United States
University of Maryland, Baltimore
InSightec; Focused Ultrasound Foundation

Completed

MR Guided Focused Ultrasound for Treatment of Neuropathic Pain

Spinal Cord Injuries | Phantom Limb Pain | Severe Neuropathic Pain Due to Radiculopathy or Radicular Injury

United States
European Society of Intensive Care Medicine

Completed

WorldwidE AssessmeNt of Separation of pAtients From Ventilatory assistancE (WEAN SAFE)

Acute Respiratory Distress Syndrome | Acute Severe Respiratory Failure

Belgium
National Taiwan University Hospital

Completed

BOO and DU and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Bladder Outlet Obstruction and Detrusor Underactivity in Women With Severe Cystocele
European Society of Intensive Care Medicine

Completed

Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE (LUNG-SAFE)

Acute Respiratory Distress Syndrome | Acute Severe Respiratory Failure

Belgium
Skane University Hospital
Lund University; The Swedish Research Council; ResMed; Vastra Gotaland Region; Region... and other collaborators

Recruiting

Effect of HIgh-flow Therapy in Long-term Oxygen Therapy (HILOT)

Interstitial Lung Disease | Chronic Respiratory Failure With Hypoxia | Chronic Obstructive Pulmonary Disease Severe

Sweden
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Effects on Biotrauma of NMBAs and PP Association During ARDS (CURA-PRONE)

Moderate to Severe Acute Respiratory Distress Syndrome

France
Kronikgune
Odense University Hospital; Assuta Ashdod Hospital; Maccabi Healthcare Services... and other collaborators

Recruiting

Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients (ADLIFE)

Heart Failure NYHA Class III | Heart Failure NYHA Class IV | Chronic Obstructive Pulmonary Disease Severe

Denmark, Germany, Israel, Spain, Sweden, United Kingdom
Children's Hospital of Philadelphia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria (RICHH)

Genetic Disease | Hypercalciuria | Idiopathic Infantile Hypercalcemia - Mild Form | Idiopathic Infantile Hypercalcaemia - Severe Form | Hypercalcemia, Idiopathic, of Infancy | Hypercalciuric Hypercalcemia

United States
Galderma R&D

Completed

To Evaluate the Efficacy and Safety of Nemolizumab for 12 Weeks in Participants With Chronic Kidney Disease With Associated Moderate to Severe Pruritus (NemoCKDaP)

Chronic Kidney Disease Associated Moderate to Severe Pruritus

Spain, United States, Hungary, Poland
The Hospital for Sick Children

Completed

Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents

Obesity | Central Sleep Apnea | Obstructive Sleep Apnea (Moderate to Severe)

Canada
Cedars-Sinai Medical Center
Alexion Pharmaceuticals, Inc.

Terminated

Complement Regulation to Undo Systemic Harm in Preeclampsia (CRUSH)

Pregnancy Related | Preeclampsia | HELLP Syndrome | Severe Preeclampsia | HELLP | Complement Regulatory Factor Defect | PNH | Eculizumab | HELLP Syndrome Second Trimester | AHUS | Complement Abnormality | HELLP Syndrome Third Trimester

United States
King's College London
Guy's & St Thomas NHS Foundation Trust

Withdrawn

LIBERATE Trial in COVID-19 (LIBERATE)

Respiratory Distress Syndrome | SARS-CoV Infection | Coronavirus

United Kingdom
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Terminated

Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan and Other ARBs on Outcomes of Coronavirus Infection? (ARBs CORONA II)

Covid19 | SARS-CoV Infection

Canada, France
Direction Centrale du Service de Santé des Armées

Active, not recruiting

Impact of Perceived Control on Operational Strain: a Study of COVID-19 Pandemic Caregivers and Military Personnel on Operational Missions (COVID-TRUST)

Covid19 | Burnout, Professional | SARS-CoV Infection | Burnout, Caregiver

France
Royal Centre for Defence Medicine
Liverpool John Moores University; Leeds Beckett University

Unknown

Influence of Military Preventive Policy for reCruit Training on COVID-19 Seroconversion (IMPACTCOVID)

Covid19 | Vitamin D Deficiency | SARS-CoV Infection | Acute Respiratory Tract Infection

United Kingdom
Centro Hospitalar de Vila Nova de Gaia/Espinho,...
Universidade do Porto

Unknown

Influence of EPICardial Adipose Tissue in HEART Diseases: EPICHEART Study (EPICHEART)

Coronary Artery Disease | Atrial Fibrillation | Coronary Arteriosclerosis | Severe Aortic Stenosis | Left Atrial Abnormality

Portugal
University Hospital, Brest

Recruiting

Risk of Ischaemic Stroke After Pulmonary Embolism in Patients With and Without Patent Foramen Ovale (EPIC-FOPCohort)

Foramen Ovale, Patent

France
British Columbia Cancer Agency
BC Cancer Foundation

Completed

The Oncopanel Pilot (TOP) Study

Gastrointestinal Stromal Tumors | Colorectal Cancer Metastatic | Advanced Melanoma | Advanced Non-Small Cell Lung Carcinoma | Patients With Diagnosed Malignancies Being Considered for Clinical Trials

Canada
Azienda Ospedaliera Universitaria Integrata Verona
Charite University, Berlin, Germany; Institut National de la Santé Et de la... and other collaborators

Recruiting

Follow-up of Covid-19 Long Term Sequelae

Coronavirus Infections | Covid19 | Coronavirus Disease 2019 | Corona Virus Infection | Coronavirus | SARS-CoV2 Infection | COVID-19 Pneumonia | SARS-CoV-2 Acute Respiratory Disease | SARS (Severe Acute Respiratory Syndrome) | COVID-19 Respiratory Infection | SARS (Disease) | COVID-19 Acute Respiratory Distress... and other conditions

Italy, Belgium, Congo, France, Netherlands, Spain
Odense University Hospital

Recruiting

Danish Diabetes Birth Registry 2 (DDBR2)

Type 1 Diabetes | Type 2 Diabetes | Parents | Fetal Complications | Family | Birth Injuries | Pregnancy in Diabetic | Maternal Diabetes

Denmark
Karolinska Institutet
Region Stockholm; Forte; Stiftelsen Frimurarna Barnhuset

Active, not recruiting

Internet-delivered ACT (I-Navigator ACT) for Parents of Children With Disabilities

Depression | Stress, Psychological | Intellectual Disability | Anxiety | Neurodevelopmental Disorders | Traumatic Brain Injury | Autism Spectrum Disorder | Parents | Attention Deficit Hyperactivity Disorder | Physical Disability

Sweden
Indiana University
Congressionally Directed Medical Research Programs; National Intrepid Center...

Recruiting

Building Emotional Self-Awareness Teletherapy (BEST) (BEST)

Concussion, Mild | Concussion, Brain | Concussion, Severe | Concussion, Intermediate | Concussion; Syndrome | Concussion Injury of Cerebrum | Concussion With Brief Loss of Consciousness | Alexithymia

United States
University of Aarhus
Aarhus University Hospital; Sygehus Lillebaelt

Recruiting

Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders (OneSTEP)

Irritable Bowel Syndrome | Fibromyalgia | Chronic Fatigue Syndrome | Bodily Distress Disorder Moderate | Bodily Distress Disorder Severe | Somatization

Denmark
University Hospital, Lille

Recruiting

Study of Genetic Determinants in Alcoholic Hepatitis and Establishment of a Multicenter Prospective Cohort of Patients With Alcoholic Liver Disease (COMADHAA)

Alcoholic Liver Disease | Severe Alcoholic Hepatitis | Alcoholic Cirrhosis

France
University College, London
Medical Research Council

Recruiting

Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation (ToTem)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myeloma | Graft Vs Host Disease | Severe Aplastic Anemia | Primary Immune Deficiency

United Kingdom
Washington University School of Medicine

Recruiting

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

Hemoglobinopathies | Bone Marrow Failure Syndromes | Metabolic Disorders | Non-malignant Disorders | Severe Sickle Cell Disease | Immunologic Disorders

United States
University of Sao Paulo General Hospital
Unity Health Toronto; University of Vermont Medical Center

Completed

A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 Pandemic (RAPID-BRAZIL)

Severe Acute Respiratory Syndrome | Coronavirus Infection | COVID | Anticoagulants and Bleeding Disorders | Thromboembolism, Venous

Brazil
ProgenaBiome
Rinati Skin, LLC

Withdrawn

A Study of ResCure™ to Treat COVID-19 Infection

Covid-19 | COVID | Corona Virus Infection | Sars-CoV2 | SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere | SARS Pneumonia | Coronavirus-19

United States
Hayandra Peduli Foundation
Koja Regional Public Hospital

Unknown

Management of Cytokine Storms in Severe COVID-19 Patients With Autologous Activated Platelet-rich Plasma Therapy

Covid19 | ARDS, Human | Sars-CoV-2 Infection | Severe covid19

Indonesia
Weill Medical College of Cornell University

Withdrawn

Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS) (VEGF-ARDS)

Acute Respiratory Distress Syndrome | Severe Sepsis

United States
Massachusetts General Hospital

Not yet recruiting

CPAP in Patients With Severe Obesity After Anesthesia

Anesthesia Morbidity | Obesity, Abdominal | Ventilator Lung | Apnea, Obstructive Sleep | Atelectases, Postoperative Pulmonary
The University of Texas Health Science Center,...
University of California, San Francisco

Active, not recruiting

Pain Biomarker Study (PBS)

Migraine | Cluster Headache | Trigeminal Autonomic Cephalgia | Hemicrania Continua | Paroxysmal Hemicrania | SUNCT | Short-Lasting Unilateral Neuralgiform Headache With Conjunctival Injection and Tearing

United States
Prof. Dr. Jörg Leuppi

Completed

High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study (VitCov)

Covid19 | Vitamin D Deficiency | Corona Virus Infection | ARDS | SARS-CoV Infection | Coronavirus

Switzerland
Sanko University

Completed

Investigation of Parents' Anxiety Level and Health Related Quality of Life in Different Types of Physical Disabilities

Cerebral Palsy | Muscular Dystrophy | Down Syndrome | Parents | Spina Bifida

Turkey
Universidade de Passo Fundo

Completed

Oral Probiotics and Secondary Bacterial Pneumonia in Severe COVID-19

Microbial Colonization | Severe COVID-19 | COVID-19 Lower Respiratory Infection | Secondary Bacterial Pneumonia

Brazil
Central Hospital, Nancy, France

Completed

Obesity and Mortality of Critically Ill Patients With COVID-19 (COV-OB-ICU)

Severe Acute Respiratory Syndrome | Obesity | COVID | Comorbidities and Coexisting Conditions

France
Postgraduate Institute of Medical Education and...

Unknown

Invasive Fungal Infections in Severe Alcohol-associated Hepatitis

Severe Alcoholic Hepatitis | Chronic Liver Disease and Cirrhosis

India
European Society of Intensive Care Medicine

Completed

Impact of Arterial CO2 Tension on Management and Outcome in Patients With Acute Hypoxemic Respirator Failure and ARDS (CO2 LUNG SAFE)

Acute Respiratory Distress Syndrome | Acute Severe Respiratory Failure

Belgium
SECRETO Study Consortium
Sahlgrenska University Hospital, Sweden; Academy of Finland; Hospital District... and other collaborators

Recruiting

Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome (SECRETO)

Ischemic Stroke | Thrombosis | Brain Infarction | Foramen Ovale, Patent

Italy, Estonia, Finland, Germany, Lithuania, Netherlands, Norway, Sweden, Turkey, United Kingdom, Greece, Portugal, Spain
University of Oulu

Recruiting

The Preterm Infants' Paracetamol Study (PreParaS)

Complication of Prematurity | Persistent Ductus Arteriosus | Pain or Discomfort in Intensive Care of Preterm Infants

Finland
Amgen

Terminated

Safety Study of AMG 228 to Treat Solid Tumors

Melanoma | Cancer | Colorectal Cancer | Advanced Solid Tumors | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Oncology | Tumors | Advanced Malignancy | Oncology Patients | Transitional Cell Carinoma of Bladder

Belgium, France, United States, Germany, Australia
University Hospital, Grenoble

Terminated

Screening of Niemann-Pick Disease, Type C in a Psychiatric Population (NPCPsy)

Psychiatric Adults Patients

France

Clinical Trials on Severely Obese Patients

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