Clinical Trials on Shock, Septic in Czechia

Total 79 results

Charles University, Czech Republic

Unknown

Fluid Responsiveness in Septic Shock Evaluated by Caval Ultrasound Doppler Examination (FRIEND)

Septic Shock | Vein Collapsibility | Intravascular Doppler | Volume Responsiveness in Septic Shock

Czechia
University Hospital Hradec Kralove
University Hospital Pilsen

Completed

Effect of Fluid Challenge on Glycocalyx

Sepsis | Septic Shock | Surgery | Endothelial Dysfunction | Anesthesia

Czechia
University Hospital Ostrava

Completed

Control of Fever in Septic Patients (COVERSEP)

Sepsis | Septic Shock | Severe Sepsis

Czechia
Brno University Hospital

Unknown

Early Identification of Sepsis in Children

Sepsis | Shock, Septic | SIRS | Sepsis, Severe

Czechia
University Hospital Ostrava

Recruiting

MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock (MADAME)

Sepsis | Septic Shock | Inflammatory Response | Multiorgan Failure

Czechia
Charles University, Czech Republic

Completed

Propafenone Versus Amiodarone in Septic Shock (PRASE)

Septic Shock | Supraventricular Arrhythmia

Czechia
Charles University, Czech Republic

Recruiting

Immune Homeostasis in Sepsis and Septic Shock (IMHOTEP)

Sepsis | Immune Deficiency | Immunologic Paralysis | Immunologic Suppression

Czechia
Anders Perner
Rigshospitalet, Denmark; Scandinavian Critical Care Trials Group; Centre for...

Active, not recruiting

The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial (CLASSIC)

Septic Shock

Sweden, Denmark, Belgium, Czechia, Italy, Norway, Switzerland, United Kingdom
University Hospital Ostrava
University Hospital Olomouc; University of Ostrava; Palacky University; Technical...

Completed

Specific miRNAs in Sepsis and Nephrotoxic Antibiotic Treatment

Sepsis | Septic Shock | Acute Kidney Injury

Czechia
AstraZeneca

Completed

A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock

Septic Shock | Severe Sepsis

Czech Republic, France, Spain, Finland, Canada, Australia, Belgium
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Charles University, Czech Republic

Unknown

Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients (ENTERPRISE)

Sepsis | Critical Illness | Septic Shock | Acid-Base Imbalance | Respiratory Acidosis | Respiratory Alkalosis

Italy, Czechia
Eli Lilly and Company

Completed

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Sepsis

Italy, United Kingdom, United States, Germany, Spain, Belgium, France, Australia, Czech Republic, Netherlands, Canada, Mexico, New Zealand, Finland, Portugal, Brazil, India, Switzerland
Charles University, Czech Republic

Completed

The Role of Myristic Acid in Serum for Early Diagnosis of Sepsis and Comparison With Selected Biomarkers of Sepsis

Systemic Inflammatory Response Syndrome | Sepsis Syndrome

Czechia
Brno University Hospital

Unknown

Utility of Presepsin in Children Sepsis

Sepsis Syndrome

Czech Republic
University Hospital Ostrava

Completed

Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients

Septic Shock | Respiratory Insufficiency | Hypoxemia | Chronic Obstructive Pulmonary Disease Exacerbation | Lung Ventilator | Hyperhydration | Respiratory Distress Syndrome, Acute

Czechia
Na Homolce Hospital
University Hospital Pilsen; General University Hospital, Prague

Completed

ExtraCorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock (ECMO-CS)

Cardiogenic Shock

Czechia
Institute for Clinical and Experimental Medicine

Recruiting

Attenuation of Post-infarct LV Remodeling by Mechanical Unloading Using Impella-CP (UNLOAD-AMI)

Myocardial Infarction | Shock, Cardiogenic | Remodeling, Ventricular

Czechia
Abbott Medical Devices
Thoratec Corporation

Terminated

Thoratec Corporation HeartMate PHP™ Cardiogenic Shock Trial

Cardiogenic Shock

Hungary, Germany, Czechia, Netherlands
Regional Hospital Liberec
Charles University, Czech Republic; University of Sao Paulo; Technology Agency...

Recruiting

The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography (N-LAT-EIT)

Lung Collapse

Czechia
University Hospital Ostrava

Completed

The Influence of Nursing Technique Applied at the Central Venous Catheter Insertion Site Upon the Incidence of Infection

Surgery | Multiorgan Failure | Haematologic Disease

Czechia
Institute for Clinical and Experimental Medicine

Completed

Monitoring of Hepatic Fat Metabolism Using Magnetic Resonance Methods

Hepatic Fat Content

Czechia
Maastricht University Medical Center
Charles University, Czech Republic; Karolinska University Hospital; Hospices... and other collaborators

Recruiting

European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO (EuroECMO-COVID)

Septic Shock | Extracorporeal Membrane Oxygenation | COVID | SARS-CoV-2 | Cardiogenic Shock | ARDS, Human | Refractory Hypoxemia

Spain, Germany, Netherlands, France, Sweden, Belgium, Austria, Portugal, Poland, United Kingdom, Italy, Lithuania, Czechia, Denmark, Greece, Hungary, Israel, Russian Federation, Switzerland
Charles University, Czech Republic
Eli Lilly and Company

Completed

Abciximab in Patients Undergoing Percutaneous Coronary Intervention for Cardiogenic Shock

Shock, Cardiogenic

Czech Republic
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
Faculty Hospital Kralovske Vinohrady

Unknown

An Upgrading of the Resuscitative Patterns by Utilization of the Balanced Crystalloids and Synthetic Colloids and the Non-Invasive Hemodynamic Monitoring During Burn Shock (FACT in BURNS)

Burns | Shock

Czech Republic
Faculty Hospital Kralovske Vinohrady
Charles University, Czech Republic

Recruiting

Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction (DAPT-SHOCK-AMI)

Acute Myocardial Infarction | Cardiogenic Shock

Czechia, Germany, Poland, Slovakia, France
Hoffmann-La Roche

Completed

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib

Hepatic Impairment

Czechia, Slovakia
University Hospital Hradec Kralove

Completed

DNA Damage in Critically Ill COVID-19 Patients

Covid19 | DNA Damage | Organ Failure, Multiple

Czechia
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
University Hospital Hradec Kralove
American Association for Thoracic Surgery

Recruiting

AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis (AOSIS)

Infections | Systemic Inflammatory Response Syndrome | Immunological Abnormality | Aortic Diseases | Thoracic Aortic Aneurysm

Czechia
Institute for the Care of Mother and Child, Prague...
Coombe Women and Infants University Hospital

Completed

Does Routine Assessment of Gastric Residuals in Preterm Neonates Influence Time Taken to Reach Full Enteral Feeding? (GRASS)

Prematurity | Necrotizing Enterocolitis of Newborn | Sepsis Newborn | Gastric Residuals Assessment

Ireland, Czechia
University Hospital Ostrava

Completed

Bolus Versus Continuous Enteral Tube Feeding

Sepsis | Trauma Injury | Major Abdominal Surgery

Czechia
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function

Hepatic Insufficiency

Hungary, Czechia, Slovakia
University Hospital Ostrava
Public Health Institute Ostrava

Completed

Presepsin in the Diagnosis of Sepsis in Critically Ill Patients

Sepsis | Infection

Czechia
University Hospital Hradec Kralove

Recruiting

Evaluation of the Severity of Right to Left Shunt in PFO Patients After Systemic Embolism

Embolism | Patent Foramen Ovale

Czechia
University Hospital Ostrava
University of Ostrava

Recruiting

BIA Assessment of Polymyoneuropathy in Critically Ill Patients

Sepsis | Respiratory Insufficiency | Trauma | Surgery

Czechia
GlaxoSmithKline

Completed

A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.

Asthma

Czechia, Slovakia
Pfizer

Completed

Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States, Belgium, Czechia, Slovakia
Pfizer

Completed

A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT

Hepatic Impairment | Healthy Participants

Czechia, Slovakia, Belgium
University Hospital Hradec Kralove

Completed

Circulatory Coherence in COVID-19 and Non-COVID-19 Patients With Sepsis

Sepsis | Viral Pneumonia

Czechia
University Hospital Ostrava

Completed

Changes in Nasal Airflow Parameters After Septoplasty and Turbinoplasty

Nasal Obstruction | Nasal Septum; Deviation | Nasal Mucosa Hypertrophy

Czechia
Vertex Pharmaceuticals Incorporated

Completed

Study of Lumacaftor in Combination With Ivacaftor in Subjects With Moderate Hepatic Impairment and Healthy Subjects

Healthy | Hepatic Impairment

Slovakia, Czech Republic
AstraZeneca
PRA Health Sciences

Completed

Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment

Hepatic Impairment

Czech Republic
University Hospital Ostrava

Completed

Correlation of Right-left Shunt Detection in Cardioembolism Etiology in Stroke Patient.

Foramen Ovale Patent

Czech Republic
University Hospital, Motol

Completed

Nitrogen Bubble Detection After Simulated Dives in Divers With PFO and After PFO Closure

Patent Foramen Ovale

Czech Republic
Janssen Infectious Diseases BVBA

Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Hepatic Impairment

Germany, Czech Republic
Pierre Fabre Medicament

Withdrawn

Hepatic Impairment Study of Encorafenib in Combination With Binimetinib in BRAF Melanoma

Hepatic Impairment | Metastatic Melanoma | Unresectable Melanoma | BRAF V600 Mutation

Spain, Czechia, Italy
The Faculty Hospital Na Bulovce

Completed

Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures

Small Bowel Obstruction | Acute Appendicitis | Perforated Gastroduodenal Ulcer

Czech Republic
Biogen

Completed

Long-Term Assessment of Remyelinating Therapy (RENEWED)

Acute Optic Neuritis

Sweden, Spain, United Kingdom, Germany, Canada, Denmark, Hungary, Belgium, Czechia, Australia, Italy
Universitaire Ziekenhuizen KU Leuven

Terminated

Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis (SCOTCH;)

Liver Cirrhosis

Spain, United Kingdom, Denmark, Germany, Czechia, Belgium, Italy

Clinical Trials on Shock, Septic in Czechia

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