Clinical Trials on Sickle Cell Syndrome Variant in Netherlands

Total 106 results

Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy (RAVOS)

Sickle Cell Disease | Sickle Cell SC Disease | Sickle Cell-SS Disease | Sickle Cell Retinopathy

Netherlands
Pfizer

Completed

A GBT021601 ADME Microtracer Study in Healthy Volunteers

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients

Sickle Cell Disease

Netherlands
Sangart

Withdrawn

Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis

Sickle Cell Disease | Anemia, Sickle Cell | Sickle Cell Anemia | Hemoglobin SC Disease | Sickle Cell Disorders | Sickle Cell Hemoglobin C Disease

France, United Kingdom, Netherlands, Turkey, Bahrain, Belgium, Brazil, Lebanon, Qatar
Academisch Medisch Centrum - Universiteit van Amsterdam...
Leiden University Medical Center

Recruiting

Do Alemtuzumab Levels Predict T Cell Chimerism After MSD SCT for SCD? (PREDICT)

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Preservation and Transfer of HBV Immunity After Allogeneic HSCT for SCD (PROTECT)

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Cerebrovascular Reserve Measurements in Sickle Cell Disease (CRUISE)

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Low Dose Iron Chelation as TReatment of Oxidative Damage in Sickle Cell Disease (TROS)

Sickle Cell Disease

Netherlands
Sanquin Research & Blood Bank Divisions
Radboud University Medical Center; Erasmus Medical Center; Academisch Medisch... and other collaborators

Unknown

Sickle Cell Disease: Targeting Alloantibody Formation Reduction; Risk Factors, and Genetics (STARRING)

Sickle Cell Disease | Alloimmunization

Netherlands
Dr. Marjon H. Cnossen MD PhD
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Recruiting

Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) (BRICK)

Sickle Cell Disease | Brain Development Abnormality

Netherlands
Modus Therapeutics AB
Ergomed

Completed

Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD

Sickle-Cell Disease

Netherlands, Oman, Jamaica, Lebanon, Bahrain, Saudi Arabia, Turkey
Pfizer

Completed

Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease

Phase 1 Sickle Cell

United States, United Kingdom, Belgium, Netherlands, Italy
Hospital Universitari Vall d'Hebron Research Institute

Active, not recruiting

GenoMed4ALL: Improving SCD Classification and Prognosis by AI (GenoMed4ALL)

Sickle Cell Disorders

Spain, Netherlands, France, Italy
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Medical Center Groningen; Erasmus Medical Center; Guy's and St Thomas... and other collaborators

Completed

N-Acetylcysteine in Patients With Sickle Cell Disease (NAC)

Sickle Cell Disease

Belgium, Netherlands, United Kingdom
Novartis Pharmaceuticals

Active, not recruiting

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients (STAND)

Sickle Cell Disease (SCD)

United States, United Kingdom, Germany, Spain, Greece, Italy, Brazil, Lebanon, Turkey, Belgium, France, Jordan, India, Finland, Canada, Colombia, Netherlands, Oman, South Africa, Panama, Ghana
CSL Behring

Completed

Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell Disease

Sickle Cell Disease

United States, United Kingdom, Netherlands
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD). (CROSSWALK-a)

Sickle Cell Disease

United States, Brazil, Italy, Spain, Kenya, Netherlands, United Kingdom, France, South Africa
UMC Utrecht
Erasmus Medical Center; Amsterdam UMC, location VUmc

Completed

Primary Ovarian Insufficiency, Polycystic Ovary Syndrome & the CardiOvascular Risk Profile (POPCORn)

Cardiovascular Diseases

Netherlands
Imara, Inc.

Terminated

A Study of IMR-687 in Subjects With Sickle Cell Disease

Sickle Cell Disease

United States, Oman, Italy, United Kingdom, Lebanon, Greece, Morocco, Tunisia, Ghana, Kenya, Netherlands, Senegal, Uganda
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) (CROSSWALK-c)

Sickle Cell Disease

United States, Spain, Brazil, United Kingdom, Italy, Turkey, Kenya, Netherlands, France, South Africa, Lebanon
Pfizer

Active, not recruiting

Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031 (034OLE)

Sickle Cell Disease

United States, Lebanon, United Kingdom, Oman, Turkey, Canada, Egypt, Kenya, France, Italy, Netherlands
Pfizer

Completed

Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) (GBT_HOPE)

Sickle Cell Disease

United States, Italy, France, United Kingdom, Netherlands, Turkey, Egypt, Canada, Jamaica, Kenya, Lebanon, Oman
Medtronic BRC

Terminated

Model 20105 Lead Study

Sick Sinus Node Syndrome

South Africa, Netherlands, Canada, Singapore
Agios Pharmaceuticals, Inc.

Recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)

Sickle Cell Disease

United Kingdom, United States, Belgium, Netherlands, Germany, Canada, Brazil, France, Israel, Italy, Lebanon, Oman, Ghana, Kenya, Nigeria, Saudi Arabia, Turkey
Radboud University Medical Center

Active, not recruiting

Preservation of Ovarian Cortex Tissue in Girls With Turner Syndrome

Turner Syndrome | Premature Ovarian Failure | Fertility Preservation | Live Birth | Ovarian Tissue Cryopreservation

Netherlands
Erasmus Medical Center
Waterloo Foundation

Not yet recruiting

Online Brief CBT Intervention for Women With PCOS (How2deal)

Depression, Anxiety | Self Esteem | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Netherlands
Maastricht University Medical Center
Sun Pharmaceutical Industries Limited

Recruiting

Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study

Carcinoma | Carcinoma, Basal Cell | Skin Cancer | Basal Cell Nevus Syndrome | Neoplasms, Basal Cell | Basal Cell Carcinoma | Locally Advanced Basal Cell Carcinoma | Metastatic Basal Cell Carcinoma | Gorlin Syndrome | Basal Cell Tumor | Neoplasm of Skin

Netherlands
UMC Utrecht
Erasmus Medical Center; Amsterdam UMC, location VUmc; The Queen Elizabeth Hospital

Completed

CoPPer Study - Complications of Polycystic Ovary Syndrome (PCOS) Pregnancy: Evaluating Risk (CoPPer)

Pregnancy Complications | Delivery Complications | Neonatal Complications

Netherlands
Novartis Pharmaceuticals

Completed

Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease (STEADFAST)

Sickle Cell Disease (SCD)

United Kingdom, Spain, Greece, Brazil, Turkey, France, United States, Netherlands, Lebanon, Ireland, Panama
Erasmus Medical Center
Roche Diagnostics

Completed

PriskA Pilot Study

Polycystic Ovary Syndrome

Netherlands
AstraZeneca

Completed

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Chronic Myelomonocytic Leukemia | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | High Risk Myelodysplastic Syndrome | Small Lymphocytic Lymphoma | B-cell Non-Hodgkin Lymphoma | Richter's Syndrome | T-cell Non-Hodgkin Lymphoma | Relapsed or Refractory...

United Kingdom, Germany, Netherlands
Actelion
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study (ASSET-3)

Sickle Cell Anemia | Pulmonary Hypertension

United States, Netherlands, United Kingdom
Maastricht University Medical Center

Recruiting

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

Quality of Life | Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
Maastricht University Medical Center

Enrolling by invitation

Reproductive Options in Inherited Skin Diseases (REPRO-ISD)

Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Xeroderma Pigmentosum | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
European Organisation for Research and Treatment...

Unknown

Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

France, Belgium, Netherlands, Germany, Italy
Erasmus Medical Center

Recruiting

Gut- and Vaginal Microbiome Composition in Association With PCOS (GuVaPCOS)

Polycystic Ovary Syndrome

Netherlands
Abbott Medical Devices

Terminated

Optimal Sensing in Atrial Tachyarrhythmia's Study (OSAT)

Paroxysmal Atrial Fibrillation | Sick Sinus Syndrome

Netherlands
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH) (ASSET-2)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

MYPP-trial: Myo-inositol Supplementation to Prevent Pregnancy Complications in Women With Polycystic Ovary Syndrome. (MYPP)

Polycystic Ovary Syndrome | Preterm Birth | Preeclampsia | Gestational Diabetes Mellitus

Netherlands
Radboud University Medical Center
Universitaire Ziekenhuizen KU Leuven

Completed

Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections (PIRAÑA)

Acute Graft Versus Host Disease | Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome

Belgium, Netherlands
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists"

Endometriosis | Ovarian Hyperstimulation Syndrome | Male Infertility | Premature Ovarian Failure | Female Infertility

Netherlands
Radboud University Medical Center

Completed

Pharmacokinetics of Micafungin Given Twice Weekly Intravenously Compared to Micafungin Given Daily to Patients at Risk for Developing an Invasive Fungal Disease (MATADOR)

Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome | Acute Graft Versus Host Disease Grade II-IV

Netherlands, Belgium
Maastricht University Medical Center
Medtronic Bakken Research Center

Completed

Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum

Heart Failure | Sick Sinus Syndrome | Left Ventricular Dysfunction | Cardiac Conduction Defect

Netherlands
Medigene AG

Withdrawn

HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloproliferative Disorders | Multiple Myeloma | Myelofibrosis | Chronic Myeloid Leukemia | Acute Lymphoid Leukemia | Malignant Lymphoma

Netherlands
Kyowa Kirin Pharmaceutical Development Ltd

Recruiting

Real World Observational Study of Poteligeo in Adult Patients With MF and SS (PROSPER) (PROSPER)

Mycosis Fungoides and Sézary Syndrome

Spain, United Kingdom, Netherlands, United States, Italy
Amsterdam UMC, location VUmc

Completed

Sitagliptin Prophylaxis for Glucocorticoid-Induced Impairment of Glucose Metabolism in Males With the Metabolic Syndrome (SPHINX)

Diabetes Mellitus | Steroid Diabetes | Glucocorticoid-induced Diabetes | Beta-cell Function

Netherlands
Medtronic BRC

Unknown

Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity.

Bradycardia; Sick Sinus Syndrome, AV Block

Germany, Denmark, Netherlands, Austria, Czech Republic, United Kingdom, Sweden, Finland, Italy, Russian Federation, Switzerland
Kiadis Pharma

Completed

Transplant-Related Mortality in Patients Undergoing a Peripheral Blood Stem Cell Transplantation or an Umbilical Cord Blood Transplantation

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States, Canada, Netherlands, Germany, Belgium, United Kingdom

Clinical Trials on Sickle Cell Syndrome Variant in Netherlands

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