Clinical Trials on Single-Gene Defects
Total 7950 results
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Jiangsu Province Centers for Disease Control and...Bejing Vigoo Biological Co., LTDCompletedSystems Biology | Early Gene | EV71 VaccineChina
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Pontificia Universidad Catolica de ChileUnknownLiver Transplantation | Gene Expression | Immunosuppression ConversionChile
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Chulalongkorn UniversityHIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...RecruitingSafety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...Thailand
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Cardiox CorporationTerminatedAtrial Septal Defect | Patent Foramen Ovale | Right to Left ShuntUnited States
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Masaryk UniversityBrno University Hospital; Roche s.r.o.RecruitingCentral Nervous System Neoplasms | Pediatric Cancer | Tumor, Brain | GEN1 Gene MutationCzechia
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Orum Therapeutics USA, Inc.RecruitingHER2-positive Breast Cancer | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein OverexpressionUnited States
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QED Therapeutics, Inc.Helsinn Healthcare SATerminatedFGFR2 Gene Mutation | Advanced CholangiocarcinomaUnited States, Belgium, Germany, Italy, Korea, Republic of, Russian Federation, Singapore, Spain, Taiwan, Thailand, United Kingdom
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Edwards LifesciencesRecruitingPulmonary Valve Insufficiency | Complex Congenital Heart Defect | Dysfunctional RVOT Conduit | Pulmonary Valve DegenerationUnited States
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University of OklahomaCompletedInflammation | Inflammatory Response | Cardiopulmonary Bypass | Congenital Heart Defect | Low Cardiac Output SyndromeUnited States
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Sameek RoychowdhuryNational Cancer Institute (NCI)WithdrawnLocally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | ALK Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Advanced Malignant Neoplasm | ALK Fusion Protein Expression | Metastatic Malignant Neoplasm in the Central Nervous System | ROS1 Gene Mutation | ALK Gene... and other conditionsUnited States
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Hospital Universitari Vall d'Hebron Research InstituteRecruitingCongenital Heart Disease | Congenital Heart Defect | Fallot TetralogySpain
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Nobel BiocareCompletedSingle Tooth Implant
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Emory UniversityCompletedHypoplastic Left Heart Syndrome | Single Ventricle | Heart Disease, CongenitalUnited States
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University Health Network, TorontoNot yet recruitingAtrial Septal Defect | Tetralogy of Fallot | Transposition of Great Vessels | Patent Foramen Ovale | Coarctation of Aorta | Fontan | Percutaneous Pulmonary Valve ImplantationCanada
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QED Therapeutics, Inc.Helsinn Healthcare SATerminatedFGFR2 Gene Mutation | Advanced CholangiocarcinomaKorea, Republic of, United States, Belgium, Spain, Taiwan, China, United Kingdom, France, Canada, Germany, Thailand, Italy, Portugal, Australia, Puerto Rico
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Taiho Oncology, Inc.Active, not recruitingAdvanced Cholangiocarcinoma | FGFR2 Gene RearrangementsUnited States, Spain, United Kingdom, Australia, Taiwan, Italy, France, Korea, Republic of, Belgium, Japan, Thailand, Germany, Brazil, Peru, Portugal, Argentina, Hong Kong, Mexico, Netherlands, Poland
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Hunan Province Tumor HospitalRecruitingNon Small Cell Lung Cancer | ALK Gene Mutation | MET Gene Mutation | EGFR Gene Mutation | ROS1 Gene MutationChina
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Columbia UniversityCompletedGlaucoma, Open-Angle | Visual Field Defect, PeripheralUnited States
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI); Eli Lilly and Company; Genentech, Inc.; Kazia... and other collaboratorsRecruitingMetastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain | NTRK Family Gene Mutation | CDK Gene Mutation | PI3K Gene Mutation | ROS1 Gene Mutation | KRAS G12C MutationUnited States
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Air Force Military Medical University, ChinaCompleted
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Quadram Institute BioscienceCompletedSingle Nucleotide PolymorphismUnited Kingdom
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Entegrion, Inc.CompletedCoagulation DefectsUnited States
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ICE Intelligent Healthcare Co., LtdNot yet recruitingAtrial Fibrillation | Arrhythmias, Cardiac | Atrial Septal Defect | Patent Foramen Ovale | Valve Disease, Heart | Supraventricular Tachycardia | Structural Heart DiseasesChina
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Centre Hospitalier Universitaire VaudoisCompletedBlood Coagulation Disorder | Congenital Heart DefectSwitzerland
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University of BathMinistry of Education, TaiwanCompletedAdipose Tissue Gene Expression
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Natera, Inc.CompletedConcurrent Single Gene and 24 Chromosome Aneuploidy Preimplantation Genetic Diagnosis (PGD) (IVF008)Any Single Gene Disorder (Cystic Fibrosis, Tay-Sachs)United States
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Intergroupe Francophone de Cancerologie ThoraciqueCompletedCarcinoma, Non-Small-Cell Lung | KRAS Gene Mutation | ALK Gene Mutation | BRAF Gene MutationFrance
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PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
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Hadassah Medical OrganizationUnknownBRCA1 Gene Mutation | BRCA2 Gene MutationIsrael
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Institut Straumann AGAvaniaActive, not recruitingDental Implants, Single-ToothGermany, Hong Kong, Portugal
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University of ZurichITI FoundationActive, not recruitingImplant-supported Single CrownsSwitzerland
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Istituto Clinico HumanitasCelgeneUnknownAcute Myeloid Leukemia | IDH2 Gene Mutation | IDH1 Gene MutationItaly
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Boston Children's HospitalCompletedCongenital Heart Disease | Single VentricleUnited States
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University Hospital, Basel, SwitzerlandRecruitingCongenital Heart Disease | Congenital Heart DefectSwitzerland
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Duke UniversityAdult Congenital Heart AssociationActive, not recruitingCongenital Heart Disease | Congenital Heart DefectUnited States
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Baylor College of MedicineTerminated
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Pierre WauthyCompletedCongenital Heart DefectBelgium
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Federation Francophone de Cancerologie DigestiveRecruitingTumors | POLD1 Gene Mutation | POLE Exonuclease Domain MutationFrance
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Calithera Biosciences, IncCompletedNSCLC | Solid Tumors | KRAS Gene Mutation | CRCUnited States
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Medical University of GrazCompletedNFAT Regulated Gene Expression in Tacrolimus Treated PatientsAustria
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First Affiliated Hospital of Chongqing Medical...Not yet recruitingCancer | Positron Emission Tomography | Stimulator of Interferon GeneChina
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SUNHO（China）BioPharmaceutical CO., Ltd.Recruiting
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Jin-Hee AhnAsan Medical CenterUnknownHER-2 Gene Amplification | HER-2 Protein Overexpression
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Hoffmann-La RocheNo longer availableCancers With NTRK, ROS1, or ALK Gene FusionsUnited States
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Joshua KanterActive, not recruitingAortic Stenosis | Atrial Septal Defect | Aortic Coarctation | Patent Ductus Arteriosus | Cardiomyopathy | Post Heart Transplant Catheter ProcedureUnited States
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Shuhui LiangRecruitingOperation | Single-balloon EnteroscopyChina
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Ruijin HospitalRecruitingSingle-Port Colorectal SurgeriesChina
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Lifetech Scientific (Shenzhen) Co., Ltd.RecruitingSingle Coronary Vessel DiseaseMalaysia
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DMG Dental Material Gesellschaft mbHRecruiting
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Alexandria UniversityActive, not recruitingDental Implants, Single-ToothEgypt