Clinical Trials on Stage IV Malignant Mesothelioma

Total 3150 results

Sumitomo Pharma Co., Ltd.

Completed

A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma

Non-Small Cell Lung Cancer | Malignant Pleural Mesothelioma

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Prognostic Stage IIIC Breast Cancer AJCC v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally... and other conditions

United States
Dr. Ronnie Shapira

Not yet recruiting

Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma (MK3475-C01)

Metastatic Melanoma | Malignant Melanoma | Immunotherapy | Malignant Melanoma Stage IV | BRAF V600E
Bristol-Myers Squibb

Recruiting

A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)

Mesothelioma, Malignant

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery

Malignant Mesothelioma | CD30-Positive Neoplastic Cells Present

United States
Armando Santoro, MD

Completed

Observational Prospective Analysis of Biological Characteristics of Mesothelioma Patients

Malignant Mesothelioma

Italy
Burzynski Research Institute

Terminated

Antineoplaston Therapy in Treating Patients With Advanced Mesothelioma

Malignant Mesothelioma

United States
University of Zurich

Completed

Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma

Switzerland
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

Biomarkers of Angiogenesis and Disease in Patients With Unresectable Malignant Mesothelioma Treated on Clinical Trial CALGB-30107

Malignant Mesothelioma
University of Pennsylvania

Completed

Autologous Redirected RNA Meso-CIR T Cells

Malignant Pleural Mesothelioma

United States
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer

Malignant Mesothelioma

United States
Alfacell

Unknown

ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen

Malignant Mesothelioma

United States, Poland, Italy, Germany
British Thoracic Society
Medical Research Council

Unknown

Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma

Malignant Mesothelioma

United Kingdom
European Organisation for Research and Treatment...

Completed

Cisplatin With or Without Raltitrexed in Treating Patients With Malignant Mesothelioma of the Pleura

Malignant Mesothelioma

Canada, France, Switzerland, Belgium, Netherlands, Italy, United Kingdom, Egypt, Germany, Peru, Poland
European Organisation for Research and Treatment...

Completed

Raltitrexed in Treating Patients With Malignant Mesothelioma That Cannot Be Surgically Removed

Malignant Mesothelioma

Italy, Netherlands
European Organisation for Research and Treatment...

Completed

Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

Belgium, Italy, Netherlands, United Kingdom
Scancell Ltd

Recruiting

SCIB1 in Melanoma Patients Receiving Either Nivolumab With Ipilimumab or Pembrolizumab (The SCOPE Study)

Melanoma (Skin) | Malignant Melanoma | Melanoma Stage IV | Melanoma Stage III

United Kingdom
Brigham and Women's Hospital
Dana-Farber Cancer Institute

Completed

Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma

United States
Maastricht Radiation Oncology
Amsterdam UMC, location VUmc

Completed

Non-invasive Imaging of Cetuximab-Zr. 89 Uptake Wit PET: a Phase I Trial in Stage IV Cancer Patients (Cetuximab Zr89)

Stage IV Cancer

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

Stage IV Anal Cancer AJCC v8 | Recurrent Cervical Carcinoma | Metastatic Malignant Neoplasm | Stage IV Penile Cancer AJCC v8 | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | Stage IV Cervical Cancer AJCC v8 | Stage IVA Cervical Cancer AJCC v8 | Stage IVB Cervical Cancer AJCC v8 | Stage... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Liver | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic...

United States
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Recurrent Melanoma | Stage IV Melanoma | Stage IIIA Melanoma | Stage IIIB Melanoma | Stage IIIC Melanoma | Acral Lentiginous Malignant Melanoma

United States
University Hospital, Caen

Unknown

Mesothelin and Osteopontin as Diagnostic Markers in Patients With Mesothelioma or Atypical Mesothelial Hyperplasia

Metastatic Cancer | Malignant Mesothelioma

France
Assistance Publique - Hôpitaux de Paris

Unknown

Efficacy of Nilotinib in First or Second Line Treatment of Primary Melanomas Stage III Unresectable Melanomas. (NILOMEL)

Stage IV Melanoma | Stage III Melanoma | Amplification | Malignant Skin Melanoma T0

France
Washington University School of Medicine
Washington University Department of Psychological and Brain Sciences

Terminated

A Self-Directed Mindfulness Meditation Intervention in Gynecologic Cancer Patients

Stage III Gynecologic Cancer | Stage IV Gynecologic Cancer

United States
Italian Network for Tumor Biotherapy Foundation
AstraZeneca

Unknown

A Study of Tremelimumab Combined With the Anti-PD-L1 MEDI4736 Antibody in Malignant Mesothelioma (NIBIT-MESO-1)

Peritoneal Mesothelioma | Pleural Mesothelioma

Italy
University Hospital, Toulouse

Completed

Rehabilitation by Effort for Patients With Advanced Bronchial Cancer (RehabKBP)

Malignant Mesothelioma | Bronchial Cancer

France
Papworth Hospital NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; University... and other collaborators

Completed

MesoTRAP: A Study Comparing Video-assisted Thoracoscopic Partial Pleurectomy/Decortication With Indwelling Pleural Catheter in Patients With Trapped Lung Due to Malignant Pleural Mesothelioma. (MesoTRAP)

Malignant Pleural Mesothelioma | Trapped Lung

United Kingdom
Papworth Hospital NHS Foundation Trust

Completed

Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma (MesoVATS)

Metastatic Cancer | Malignant Mesothelioma

United Kingdom
Glendale Adventist Medical Center d/b/a Adventist...
GUARDANT HEALTH

Recruiting

Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liquid Molecular Testing Panel in the Community Setting ("DINOSAur II") (DINOSAur II)

Stage III Solid Tumors | Stage IV Solid Tumors

United States
National Cancer Institute (NCI)

Completed

Phase II Study of IMC-A12 in Patients With Mesothelioma Who Have Been Previously Treated With Chemotherapy

Peritoneal Mesothelioma | Pleural Mesothelioma

United States
Ain Shams University

Recruiting

Effect of HITHOC After Pleurectomy Decortication for Treatment of Malignant Pleural Mesothelioma

Chemotherapy Effect | Malignant Pleural Mesothelioma

Egypt
3-C Institute for Social Development
University of North Carolina, Chapel Hill

Completed

Living With CKD: An E-Learning Platform for Adolescents With CKD About the Disease and Its Management (CKD Delp)

Chronic Kidney Diseases | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease stage4 | Pediatric Kidney Disease | Chronic Kidney Disease stage3 | Chronic Kidney Disease Stage V | Chronic Kidney Disease, Stage IV (Severe) | Chronic Kidney Disease Stage 2 | Chronic Kidney Disease, Stage I

United States
City of Hope Medical Center

Recruiting

Early Onset Colorectal Cancer Detection (ENCODE)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage IV | Colorectal Neoplasms Malignant | Colorectal Cancer Stage I

United States, Japan, Italy, Spain
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

Pleural Biphasic Mesothelioma | Pleural Sarcomatoid Mesothelioma

United States
Targovax Oy
Theradex

Unknown

A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma

To Determine Safety, Tolerability and Efficacy of ONCOS-102 in Combination With Chemotherapy

Spain, France
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Optical Coherence Tomography of the Airway for Lung Cancer or Lung Disease

Lung Cancer | Metastatic Cancer | Malignant Mesothelioma | Precancerous Condition | Nonmalignant Neoplasm

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Real World Study of MPM in China

Diagnoses Disease | Malignant Pleural Mesothelioma | Prognosis | Treatments

China
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Inhaled Doxorubicin in Treating Patients With Advanced Solid Tumors Affecting the Lungs

Lung Cancer | Metastatic Cancer | Malignant Mesothelioma

United States
Glendale Adventist Medical Center d/b/a Adventist...
Caris Life Sciences

Recruiting

Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Molecular Testing Panel in the Community Setting ("DINOSAur") (DINOSAur)

Stage III Solid Tumors | Stage IV Solid Tumors

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Malignant Gastrointestinal Neoplasm | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Gallbladder Carcinoma | Stage IV Gallbladder Cancer | Stage IV Gastric Cancer | Stage IIIA Gallbladder Cancer | Stage... and other conditions

United States
University Hospital Tuebingen

Unknown

Early Therapy Response Monitoring in Melanoma Patients Using PET/MRI

Malignant Melanoma Stage IV

Germany
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Completed

Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners

Stage IV Lung Cancer | Stage IV Skin Melanoma | Stage IIIB Skin Melanoma | Stage IIIC Skin Melanoma | Stage III Uterine Corpus Cancer | Stage IV Uterine Corpus Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Malignant Female Reproductive System Neoplasm | Stage III... and other conditions

United States
University Hospital, Antwerp
Roche Pharma AG; Algemeen Ziekenhuis Maria Middelares; Kom Op Tegen Kanker; Vitaz

Recruiting

Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma (Immuno-MESODEC)

Malignant Pleural Mesothelioma

Belgium
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Peritoneal Carcinomatosis | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Malignant Uterine Neoplasm | Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Colorectal Carcinoma | Stage... and other conditions

United States
Maisonneuve-Rosemont Hospital

Completed

Survival of Peritoneal Mesothelioma After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy (HIPEC)

Peritoneal Mesotheliomas

Canada
University of Glasgow

Completed

Radiation Therapy in Preventing Metastatic Cancer in Patients Who Have Diagnostic Procedures to Identify Malignant Mesothelioma

Malignant Mesothelioma | Perioperative/Postoperative Complications

United Kingdom
M.D. Anderson Cancer Center

Recruiting

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

Malignant Solid Neoplasm | Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage... and other conditions

United States
Wales Cancer Trials Unit
Velindre NHS Trust; June Hancock Mesothelioma Research Fund; Velindre Cancer...

Unknown

A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma (SKOPOS)

Mesothelioma | Malignant | Pleural

United Kingdom
Niguarda Hospital
University of Turin, Italy; Fondazione del Piemonte per l'Oncologia

Completed

Donation of Post Mortem Tumor Tissues (DONUM)

NSCLC Stage IV | CRC | CUP

Italy

Clinical Trials on Stage IV Malignant Mesothelioma

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