Clinical Trials on Subjects Presenting With Normal or With Ocular Pathology in United States

Total 478 results

Topcon Medical Systems, Inc.

Completed

Clinical Validation of New OCT System

Subjects Presenting With Normal or With Ocular Pathology

United States
Topcon Medical Systems, Inc.

Completed

TopQ Cut-off Score Validation Study for 3D OCT-1 Maestro

Subjects Presenting With Normal Eyes

United States
Topcon Medical Systems, Inc.

Completed

Retinal Fundus Camera Evaluation

Normal Healthy Subjects With no Known Ocular Diseases

United States
Topcon Medical Systems, Inc.

Completed

Maestro Agreement and Precision Study II

Normal Healthy Subjects With No Known Ocular Diseases | Glaucomatous Eyes | Eyes With Retinal Diseases

United States
Topcon Medical Systems, Inc.

Completed

Clinical Study of the Optic Disc Parameters

Normal Healthy Subjects With No Known Ocular Diseases | Glaucomatous Eyes | Eyes With Retinal Diseases

United States
Optovue

Completed

Comparison of OCT and OCTA-based Ocular Measurements to Those of Predicate

Normal Eyes and Eyes With Ocular Pathologies

United States
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency

Subjects With Varying Degrees of Renal Insufficiency and | Subjects With Normal Renal Function

United States
Brahms AG

Recruiting

Risk Stratification Using Midregional Proadrenomedullin in the ED

Patients Presenting With Suspicion of Infection to the ED

United Kingdom, Spain, Italy, France
DeNova Research

Completed

A Study to Assess the Efficacy of Skin Rejuvenation Therapy in Combination With Neurotoxin and Full Facial Filler Treatments

Subjects Requesting and Requiring Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers

United States
Alcon Research

Completed

TOBRADEX Ophthalmic Suspension Versus Tobramycin 0.3%/Dexamethasone 0.05% Ophthalmic Suspension

Ocular Inflammation Associated With Blepharaconjunctivitis

United States
AstraZeneca
Eli Lilly and Company; i3 Drug Safety

Completed

A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents

Type 2 Diabetes (Treated With Exenatide or Other Oral Antidiabetic Therapies) | Healthy Subjects (Treated With no Diabetes Therapies)

United States
Nidek Co. LTD.

Completed

Comparative Study of the Optical Biometer for Measurements of the Eye

Cataract | Normal Non-fluency | Aphakic Eye | Eyes With Corneal Abnormality

United States
Sun Pharma Advanced Research Company Limited

Completed

Evaluation of Efficacy and Safety of SDN-037

Inflammation and Pain Associated With Ocular Surgery

United States
MaineHealth
HumanN

Completed

Treatment of HFpEF With Nitrate Supplement

Heart Failure With Normal Ejection Fraction

United States
Virginia Commonwealth University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Interleukin-1 Blockade in HF With Preserved EF (D-HART2)

Heart Failure With Normal Ejection Fraction

United States
University of Oklahoma

Completed

Neuromodulation to Treat Patients With Heart Failure With Preserved Ejection Fraction

Heart Failure With Normal Ejection Fraction

United States
University of California, Irvine

Completed

Optical Coherence Tomography of the Gastrointestinal Tract (OCT)

Barrett's Esophagus With or Without Dysplasia | Patients With Early Esophageal or Gastric Cancer | Patients With Intestinal Metaplasia of the Stomach

United States
Greater Baltimore Medical Center

Withdrawn

Panomics Relationships in the Epidemiology of Cancer Through In Silico Expression (PRECISE)

Cancer | Patients With Clinical and Environmental Risk Factors for Cancer | Patients With a Suspected or Confirmed Diagnosis of Cancer

United States
Rutgers, The State University of New Jersey
Monell Chemical Senses Center

Completed

Ibuprofen Inhibits Human Sweet Taste

Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Ibuprofen Solution in Healthy Participants | Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Naproxen Solution in Healthy Participants

United States
Biosite

Completed

BRAIN (Biomarker Rapid Assessment of Ischemic iNjury)

Stroke | Stroke Mimic(Conditions Presenting With Stroke-like Conditions)

United States, Canada, Germany, Switzerland, United Kingdom
Tyligand Bioscience (Shanghai) Limited

Recruiting

Phase I Study of TSN084 in Patients With Advanced Malignant Tumors.

Cancer (With or Without Metastasis)

United States
Johns Hopkins University
Medtronic; Biosense Webster, Inc.

Not yet recruiting

Ablation Versus Medical Management of Atrial Fibrillation in HFpEF (AMPERE)

Atrial Fibrillation | Heart Failure With Normal Ejection Fraction

United States
Virginia Commonwealth University

Completed

Unsaturated Fatty Acids Enriched-diet to Improve Cardiorespiratory Fitness, Metabolic Flexibility and Glucose Tolerance in Obese Patients

Obesity | Heart Failure With Normal Ejection Fraction

United States
Abramson Cancer Center of the University of Pennsylvania

Terminated

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

Subjects With Severe, Refractory Sclerotic Skin Changes

United States
Massachusetts Eye and Ear Infirmary
Emory University; University Hospitals Cleveland Medical Center; Rady Children... and other collaborators

Withdrawn

Postoperative Ibuprofen Use and Risk of Bleeding in Pediatric Tonsillectomy

Tonsillectomy With or Without Adenoidectomy

United States
Amgen

Completed

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a)) (ANITSCHKOW)

Subjects With Hyperlipidemia, Dyslipidemia

Canada, Netherlands, United States
Mayo Clinic

Completed

International Consortium Investigating Early Vitrectomy in Diabetic Macular Edema Patients (ICV-DME)

Diabetes With Diabetic Retinopathy With Macular Edema

United States
Genticel
PPD

Terminated

Safety, Tolerability, and Immunogenicity of GTL001 Vaccine Adjuvanted With Imiquimod Cream in HPV 16- and/or HPV 18-Infected Women Aged 25 to 65 Years, With Normal Cytology, ASCUS, or LSIL

HPV 16- and/or HPV 18-Infected Women With Normal Cytology, ASCUS, or LSIL

United States
Shire

Completed

Evaluation of Prucalopride in Male Subjects With Chronic Constipation.

Male Subjects With Chronic Constipation

Belgium, Romania, Poland, Netherlands, Germany, United Kingdom, Bulgaria, Czechia, Denmark, France
Baylor Research Institute

Recruiting

Virtual Reality Pain Study (VR Pain)

Hospitalized Patients 18 Years of Age or Older With Pain

United States
University of Iowa

Completed

Cool vs Room-temperature Artificial Tears

Eye Pain | Ocular Surface Disease | Cystoid Macular Edema | Central Retinal Vein Occlusion With Macular Edema | Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis) | Exudative Age-Related Macular Degeneration, Unspecified Eye | Dry Eye Sensation

United States
Tenax Therapeutics, Inc.

Active, not recruiting

Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients

Heart Failure With Normal Ejection Fraction | Hypertension Pulmonary Secondary Heart Failure | Right Sided Heart Failure With Normal Ejection Fraction

United States
University of Washington
National Cancer Institute (NCI)

Completed

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

Chronic Myelomonocytic Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22... and other conditions

United States
National Cancer Institute (NCI)

Completed

PXD101 in Treating Patients With Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Alice Mims
Karyopharm Therapeutics Inc

Completed

Selinexor and Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Sumithira Vasu

Completed

Decitabine, Donor Natural Killer Cells, and Aldesleukin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
David Iberri

Terminated

Decitabine and Midostaurin in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) With Multilineage Dysplasia Following Myelodysplastic Syndrome, in Adults | AML (Adult) With 11q23 (MLL) Abnormalities | AML (Adult) With Del (5q) | AML (Adult) With Inv (16) (p13; q22) | AML (Adult) With t (16;16) (p13; q22) | AML (Adult) With t (8; 21) (q22; q22) and other conditions

United States
National Cancer Institute (NCI)

Completed

Decitabine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Secondary Acute Myeloid Leukemia and other conditions

United States
Alison Walker
Novartis; Millennium Pharmaceuticals, Inc.

Completed

Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid... and other conditions

United States
Roswell Park Cancer Institute
Celgene Corporation

Completed

Lenalidomide and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
Vitreous -Retina- Macula Consultants of New York

Completed

To Evaluate The Role of Intravitreal Aflibercept Injection (2.0 mg) in the Management of Previously Treated Patients With Exudative AMD

AMD (With Persistent or Recurrent Fluid Despite Monthly Intravitreal Anti-VEGF Therapy)

United States
DeNova Research

Completed

A Study to Examine the Effects of Cosmeceutical Therapy in Subjects Undergoing Full Facial Rejuvenation

Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
St. Louis University
Janssen Services, LLC

Withdrawn

Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis

Sickle Cell Disease | Hb-SS Disease With Vasoocclusive Pain | Hemoglobin SS Disease With Vasoocclusive Crisis | Other Sickle Cell Disease With Vaso-Occlusive Pain | Hemoglobin SS Disease With Crisis

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
Virginia Commonwealth University
American Heart Association

Completed

Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Obesity and HFpEF (UFA-Preserved2)

Obesity | Heart Failure With Normal Ejection Fraction

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
National Cancer Institute (NCI)

Completed

GTI-2040 and High-Dose Cytarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Adult Acute Myeloid Leukemia...

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Bendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDS

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Untreated Adult Acute Myeloid... and other conditions

United States
Carl Zeiss Meditec, Inc.
DataMed Devices Inc.

Completed

Repeatability and Reproducibility of Cirrus HD-OCT Measurements of Illumination Areas Under the Retinal Pigment Epithelium

Advanced Dry AMD With Geographic Atrophy

United States

Clinical Trials on Subjects Presenting With Normal or With Ocular Pathology in United States

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