Clinical Trials on Submental Laxity

Total 817 results

Syneron Medical

Unknown

Treatment With the Profound System for Submental Laxity

Submental Laxity

United States
10xBio, LLC

Completed

A Safety and Tolerability Study of 10XB-101 Injections in Adult Subjects With Extra Fat Under the Chin ("Double Chin")

Submental Fat

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Evaluate the Efficacy and Safety of DWJ211 in Patient With Moderate or Severe Submental Fat (SMF)

Submental Fat

Korea, Republic of
Raziel Therapeutics Ltd.

Completed

Efficacy and Safety of RZL-012 on Submental Fat Reduction

Submental Fat

United States
Raziel Therapeutics Ltd.

Completed

An Open Label Study That Will Test Safety and Efficacy of RZL-012 Injection Into the Submental Fat in Chinese vs. Non-Chinese Subjects.

Submental Fat

United States
Raziel Therapeutics Ltd.

Completed

An Open-label Study That Will Test a Second Treatment Session of RZL-012.

Submental Fat

United States
Medy-Tox

Completed

Evaluate the Efficacy and Safety of MT921 in Subjects With Moderate to Severe Submental Fat

Submental Fat

Korea, Republic of
Allergan

Terminated

Evaluation of the Safety and Effectiveness of BELKYRA® Inj. for the Treatment of Patients With Submental Fullness Due to Submental Fat: A Postmarketing Surveillance Study in Korea

Submental Fullness

Korea, Republic of
Medy-Tox

Completed

A Phase II Study to Evaluate the Efficacy and Safety of MT921 in Subjects With Moderate to Severe Submental Fat

Submental Fat

Korea, Republic of
Kythera Biopharmaceuticals

Completed

Condition of Submental Fullness and Treatment Outcomes Registry (CONTOUR)

Submental Fullness

United States, Canada
Neothetics, Inc

Completed

Study to Evaluate the Safety and Efficacy of LIPO-202 for the Reduction of Submental Subcutaneous Fat

Submental Fat

United States
Merz North America, Inc.
Ulthera, Inc

Completed

Evaluation of the Effectiveness and Safety of the Ulthera® DeepSEE® System for Treating Skin Laxity in the Lower Face and Submentum

Improvement in Skin Laxity of the Lower Face and Submentum

China
Raziel Therapeutics Ltd.

Completed

Evaluation the Effects of Various Treatments on RZL-012-Induced Adverse Events

Submental Fat

United States
Raziel Therapeutics Ltd.

Completed

A Single Blind, Randomized, Placebo-controlled, Phase 2a, 2-cohort Study for the Evaluation of Safety and Efficacy of RZL-012 for Submental Fat Reduction in Healthy Volunteers.

Submental Fat

United States
10xBio, LLC

Active, not recruiting

A Safety and Tolerability Study of 10XB-101 Injection in Adult Subjects With Submental Fat

Submental Fat

United States
Kythera Biopharmaceuticals

Completed

Long-term Follow-up Study on Safety and Maintenance of Efficacy of ATX-101

Healthy | Submental Fat

United States, Canada
Kythera Biopharmaceuticals

Completed

Long Term Follow-up Study on Safety and Maintenance of Efficacy of ATX-101

Healthy | Submental Fat

United States, Canada, Australia, United Kingdom
AMIpharm Co., Ltd.

Completed

Evaluate Pharmacokinetic/Pharmacodynamic and Safety/Tolerability of AYP-101 in Healthy Subjects

Healthy Subjects | Submental Fat

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Completed

Clinicial Trial to Evaluate the Efficacy and Safety of DWJ211 in Patient With Moderate or Severe Submental Fat (SMF)

Treatment for Submental Fat

Korea, Republic of
Kythera Biopharmaceuticals

Completed

Open-Label Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area

Moderate or Severe Submental Fullness

United States
Kythera Biopharmaceuticals

Completed

Patient Experience Study of Deoxycholic Acid Injection

Moderate or Severe Submental Fullness

United States
Kythera Biopharmaceuticals

Completed

Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area (REFINE-1)

Moderate or Severe Submental Fullness

United States, Canada
AMIpharm Co., Ltd.

Completed

Evaluate the Efficacy and Safety of Polyene Phosphatidylcholine Injection (AYP-101) for the Reduction of Submental Fat (AYP-101)

Moderate or Severe Submental Fullness

Korea, Republic of
Rejuven Dermaceutical Co., Ltd.

Completed

RJV001 Study in Adults Receiving Abdominoplasty

Submental Fat (SMF) | Double Chin

United States
Kythera Biopharmaceuticals

Completed

Phase 2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat

Moderate or Severe Submental Fullness

Australia, Canada, United Kingdom
Kythera Biopharmaceuticals

Completed

Deoxycholic Acid Injection Submental Fat (SMF) Magnetic Resonance Imaging (MRI) and Subject-reported Outcome Measures Study

Moderate or Severe Submental Fullness

United States
Kythera Biopharmaceuticals
Bayer

Completed

Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat

Moderate or Severe Submental Fullness

Belgium, France, Germany, Italy, Spain, United Kingdom
AMIpharm Co., Ltd.

Completed

Determine the Dosing Interval and Optimal Dose of AYP-101 for the Reduction of Submental Fat in Chin Area

Moderate or Severe Submental Fullness

Korea, Republic of
Topokine Therapeutics, Inc.

Suspended

Safety and Feasibility Study of XAF5 Gel for Reduction of Submental Fat

Excess Submental Fat ("Double Chin")
Kythera Biopharmaceuticals
Bayer

Completed

Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat

Moderate or Severe Submental Fullness

Germany, France, Belgium, Spain, United Kingdom
Kythera Biopharmaceuticals

Completed

Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat (ATX-101)

Moderate or Severe Submental Fullness

United Kingdom, Canada, Australia
Kythera Biopharmaceuticals

Completed

Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area

Moderate or Severe Submental Fullness

United States, Canada
Kythera Biopharmaceuticals

Completed

Safety Study of ATX-101 (Deoxycholic Acid) in Subjects With Mild or Extreme Fullness of Submental Fat

Efficacy | Safety | Moderate to Severe Convexity of Submental Fat

United States
Kythera Biopharmaceuticals

Completed

Safety Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area in Subjects 65 to 75 Years of Age

Efficacy | Safety | Moderate to Severe Convexity of Submental Fat

United States
Seoul National University Hospital

Completed

Effect of Vaginal Radiofrequency Therapy on Vaginal Laxity : Pilot Trial (ROSE)

Vaginal Laxity

Korea, Republic of
Poitiers University Hospital

Completed

Physiological Upper Eyelid Laxity (LAX)

Eyelid Laxity

France
Centre Hospitalier Universitaire de Nice

Recruiting

Evaluation of Anterior Tibial Translation of the Knee in Healthy Women, at Two Times of the Menstrual Cycle, on Hormonal Contraceptives or Not (FLEX) (FLEX)

Ligament; Laxity

France
Rocky Mountain Biosystems, Inc.

Completed

Investigation of Radiofrequency Device for Treatment of Wrinkles and Rhytides

Laxity of Skin

United States
Rocky Mountain Biosystems, Inc.

Completed

Study of Radiofrequency Device for Use in Non-Invasive Cosmetic Procedures

Laxity of Skin

United States
xpgeng

Not yet recruiting

The Approach of Biliary Drainage in Hepatolithiasis Patients With Sphincter of Oddi Laxity (BD)

Sphincter of Oddi Laxity
Cairo University

Unknown

Effect of the Submental Artery Island Flap Versus Maxillary Obturator Prosthesis

Patient With Partial Maxillectomy | Submental Island Flap | Maxillary Obturator

Egypt
Genzyme, a Sanofi Company

Completed

A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS) (FSGS)

Primary Focal Segmental Glomerulosclerosis

United States, Brazil, Germany, Italy, Spain
TingBo Liang

Unknown

Randomized Controlled Trial of Treating Hepatolithiasis (Accompanied With SOL) With Choledochojejunostomy

Hepatolithiasis | Sphincter of Oddi Laxity

China
Complexa, Inc.
Medpace, Inc.; MicroConstants; Kidney Research Network, formerly NephCure Accelerating... and other collaborators

Completed

FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)

Primary Focal Segmental Glomerulosclerosis

United States
National Institute of Diabetes and Digestive and...
Genentech, Inc.; Indiana University

Completed

Rituximab Treatment of Focal Segmental Glomerulosclerosis

Focal Segmental Glomerulosclerosis (FSGS)

United States
Cairo University
Minia University; Deraya University

Completed

Ultrasound Imaging of Core Muscles Activity in Multiparous Women With Vaginal Laxity: A Cross-Sectional Study

Vaginal Laxity

Egypt
The University of Texas Medical Branch, Galveston
United States Department of Defense

Completed

Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects

Segmental Long Bone Defects

United States
Mayo Clinic
University Health Network, Toronto; National Institute of Diabetes and Digestive... and other collaborators

Completed

A Pilot Study to Assess the Efficacy of Rituximab Therapy in Treatment Resistant FSGS

Primary Focal Segmental Glomerulosclerosis

Canada, United States
Mallinckrodt ARD LLC

Completed

Acthar for Treatment-Resistant or Treatment-Intolerant Proteinuria (PODOCYTE)

Idiopathic Focal Segmental Glomerulosclerosis

United States, Argentina, Turkey, Peru, Australia, Chile, Mexico
University of St. Augustine for Health Sciences

Completed

Hormone Induced Effects on Ligament Laxity and Lower Extremity Motor Control

Hormone Influence on Ligament Laxity and Motor Control

United States

3

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