Clinical Trials on Substrate Metabolism

Total 54777 results

Danish Dementia Research Centre

Active, not recruiting

Novel Diagnostic and Disease Stage Biomarkers in AD (TRACK-AD)

Alzheimer Disease | Mild Cognitive Impairment | Vascular Dementia | Dementia With Lewy Bodies | Healthy Controls | Neuro-Degenerative Diseases

Denmark
Laminate Medical Technologies

Completed

VasQ External Support for Arteriovenous Fistula

Diabetes Mellitus | Renal Failure | ESRD | Aneurysm | Kidney Failure | Renal Disease | Arterio-Venous Fistula | Steal Syndrome

United States
Greece 2021 Committee
Greek Alzheimer's Association and Related Disorders; Ionian University

Enrolling by invitation

Digitally-enhanced, Decentralized, Multi-omics Observational Cohort (ANANEOS)

Dementia | Cognitive Change | Alzheimer Disease | Mild Cognitive Impairment | Parkinson's Disease and Parkinsonism | Presymptomatic Disease | Memory Loss (Excluding Dementia)

Greece
Skilled Skin S.L.

Completed

Clinical Investigation EUCLIDES-01 for the Calculation of the Area of Skin Lesions

Surgical Wound | Diabetic Foot Ulcer | Skin Lesion | Pressure Ulcer | Hematoma | Venous Ulcer | Ischemic Ulcer | Arterial Ulcer | Diabetic Neuropathic Ulcer | Traumatic Ulcer | Ulcer, Skin

Spain
Anglia Ruskin University
University of Melbourne; Alzheimer's Society; Norwegian Academy of Music; Cambridgeshire... and other collaborators

Completed

Home-based Family Caregiver-delivered Music and Reading Interventions for People With Dementia (HOMESIDE)

Depression | Quality of Life | Dementia | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Alzheimers | Behavioural and Psychiatric Symptoms of Dementia

United Kingdom, Australia, Germany, Norway, Poland
Lokman Hekim Üniversitesi
Hacettepe University

Completed

Examination of Lower Urinary System Symptoms With Duchenne Muscular Dystrophy

Quality of Life | Lower Urinary Tract Symptoms | Muscle Weakness | Duchenne Muscular Dystrophy | Pelvic Floor Muscle Weakness | Posture Disorders in Children | Lumbar Lordosis

Turkey
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV/Hib Vaccine Primary & Booster Vaccinations Versus Co-administration of DTaP-IPV and Hib Vaccine in Japanese Infants

Pertussis | Tetanus | Diphtheria | Bacterial Meningitis | Poliomyelitis

Japan
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Phase I/II Thymus Transplantation With Immunosuppression #950 (#950)

DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome | Complete Atypical DiGeorge Anomaly | Complete Atypical DiGeorge Syndrome

United States
Steno Diabetes Center Copenhagen

Enrolling by invitation

Diabetic Neuropathy Screening Study 1.1 + Substudy 1.2-1.3-1.4 (DANES)

Diabetic Foot | Diabetic Neuropathies | Foot Deformities | Autonomic Neuropathy | Distal Peripheral Sensory Neuropathy | CAN

Denmark
RedDress Ltd.

Completed

A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1

Trauma Injury | Diabetic Foot Ulcer | Venous Leg Ulcer | Pressure Ulcer | Skin Tear | Chronic Ulcer

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Unknown

Autologous Fat Grafting in the Treatment of Critical Limb Ischaemia

Diabetic Foot | Scleroderma, Systemic | Ischemic Leg | Critical Limb Ischemia | Ischemic Ulcer | Ischemic Feet | Peripheral Arterial Disease - PAD | Thrombo Angiitis Obliterans

Italy
Uptown Eye Specialists

Unknown

Diabetic Macular Edema - Obstructive Sleep Apnea Relationship Study (DME-OSA)

Diabetic Macular Edema | Sleep Apnea | Non Proliferative Diabetic Retinopathy

Canada
GlaxoSmithKline

Completed

Study to Determine the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals; Infanrix Hexa at 2, 4 and 6 Months of Age in Healthy Infants

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Haemophilus Influenzae Type b

United States
GlaxoSmithKline

Completed

Study to Evaluate the Immunogenicity and Reactogenicity of a Booster Dose of GSK2036874A Vaccine in Healthy Toddlers

Hepatitis B | Tetanus | Diphtheria | Haemophilus Influenzae Type b | Whole Cell Pertussis | Poliomyelitis Vaccines

Philippines
Bristlecone Health, Inc.
University of Minnesota

Unknown

Photobiomodulation & Ketogenic Diet for Treatment of Mid-periphery Retinal Disorders for Alzheimer's Disease Prevention

Diabetic Macular Edema (DME) | Age-related Macular Degeneration (AMD) | Diabetic Retinopathy (DR) | Mid-peripheral Drusen Formation

United States
GlaxoSmithKline

Terminated

Feasibility Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants at 3, 5 and 11 Months of Age.

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Neisseria Meningitidis | Haemophilus Influenzae Type b

Slovakia
U.S. Wound Registry

Unknown

Cellular and Tissue Based Therapy Registry (CTPR)

Diabetic Foot Ulcers | Pressure Ulcer | Surgical Wound Dehiscence | Venous Stasis Ulcer | Chronic Non Healing Wound

United States
GlaxoSmithKline

Completed

Immunogenicity and Safety of DTPa-HBV-IPV/Hib Compared to DTPa-IPV/Hib and HBV Administered Concomitantly

Hepatitis B | Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Influenzae Type b (Hib)
Cloud DX Inc.

Completed

Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station

Pneumonia | Hypertension | Diabetes Mellitus | Atrial Fibrillation | Urinary Tract Infection | Healthy Volunteers | OSA | COPD | Leukocytosis | Acute Otitis Media | Iron Deficient Anemia

Canada
GlaxoSmithKline

Completed

Comparison of Immunogenicity and Reactogenicity of INFANRIX™ HEXA and HEXAVAC™ Vaccines as a Primary Vaccination Course

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Haemophilus Influenzae Type b

Italy, Sweden, Finland
Novartis Vaccines

Completed

A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Conjugate Vaccine In Adolescents

Pertussis | Tetanus | Human Papillomavirus Infection | Meningococcal Meningitis

Costa Rica
Federal Research Institute of Pediatric Hematology...

Completed

Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation (45RA_NEG_DLI)

Leukemia, Myeloid, Acute | Opportunistic Infections | Graft vs Host Disease | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Bone Marrow Failure Syndromes | Immune Deficiency Disease

Russian Federation
LG Life Sciences

Unknown

Post-authorization Safety Study of Euforvac-Hib Vaccine for Active Primary Immunization in Infants From 6 Weeks

Hepatitis B | Pertussis | Tetanus | Diphtheria | Haemophilus Influenza Type B
Sanofi Pasteur, a Sanofi Company
Merck Sharp & Dohme LLC

Completed

Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar®

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio

Canada
California Cancer Consortium
National Cancer Institute (NCI)

Completed

Decitabine in Treating Patients With Melanoma or Other Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Fatigue | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition

United States
Massachusetts General Hospital

Withdrawn

Treating Sleep/Wake Cycle Disturbances in Basal Ganglia Disorders With Ramelteon

Parkinson's Disease | Sleep Disorders | Dementia With Lewy Bodies | Huntington's Disease | Circadian Dysregulation

United States
NYU Langone Health
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition

United States
Skane University Hospital

Completed

Nerve Morphology in Diabetic Patients

Diabetes Complications | Carpal Tunnel Syndrome | Peripheral Neuropathy | Entrapment Neuropathies

Sweden
National Institute of Allergy and Infectious Diseases...

Completed

Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related Disorders

Chronic Granulomatous Disease | Leukocyte Disorder | Job's Syndrome | Chediak Higashi Syndrome

United States
Fairview University Medical Center

Unknown

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Hemophagocytic Lymphohistiocytosis | Graft Versus Host Disease | Chediak-Higashi Syndrome | Virus-Associated Hemophagocytic Syndrome | X-Linked Lymphoproliferative Syndrome | Familial Erythrophagocytic Lymphohistiocytosis

United States
University of Arkansas

Withdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Pancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma Syndrome

United States
King's College London

Recruiting

The Living With a Long-Term Condition Study (LTC)

Liver Diseases | Heart Diseases | Heart Failure | Stroke | Cerebrovascular Disorders | Epilepsy | Pain | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Cancer | Arthritis | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Migraine | Hepatitis | Atrial Fibrillation | Asthma | Endometriosis | Dementia | Fibromyalgia | Celiac... and other conditions

United Kingdom
Chinese University of Hong Kong

Recruiting

Safety and Efficacy of Fecal Microbiota Transplantation

Alcohol Dependence | Multiple Sclerosis | Obesity | Diabetes Mellitus | Hepatic Encephalopathy | Irritable Bowel Syndrome | Constipation | Celiac Disease | Crohn Disease | Ulcerative Colitis | Liver Disease | Idiopathic Thrombocytopenic Purpura | Clostridium Difficile Infection | Alopecia | Autism | Multiple Organ Dysfunction... and other conditions

Hong Kong
Masonic Cancer Center, University of Minnesota

Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Common Variable Immunodeficiency | Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | X-linked Lymphoproliferative Disease | Langerhan's Cell Histiocytosis | Chediak-Higashi Syndrome | Griscelli Syndrome | Bare Lymphocyte Syndrome | SCID | Omenn's Syndrome | Reticular... and other conditions

United States
National Cancer Institute (NCI)

Withdrawn

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Hematopoietic and Lymphoid Cell Neoplasm | Lynch Syndrome | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central... and other conditions

United States, Canada
Fairview University Medical Center

Terminated

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Immunologic Deficiency Syndromes | Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Graft Versus Host Disease | X-linked Agammaglobulinemia | Chediak-Higashi Syndrome | Virus-Associated... and other conditions

United States
Bayer

Not yet recruiting

A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure

Chronic Kidney Disease | Arterial Hypertension | Non-proliferative Diabetic Retinopathy

Germany
Luye Pharma Group Ltd.

Not yet recruiting

A Phase 1, SAD Study to Evaluate the Safety and Tolerability of LY03017

Negative Symptoms of Schizophrenia | Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis | Hallucinations and Delusions Associated With Parkinson Disease Psychosis

China
prof. dr. Koen Van Laere
Universitaire Ziekenhuizen KU Leuven; KU Leuven; University Hospital, Ghent; Fund...

Not yet recruiting

[18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DBL vs. AD

Parkinson Disease | Alzheimer Disease | Dementia With Lewy Bodies | MSA - Multiple System Atrophy

Belgium
Pauls Stradins Clinical University Hospital

Recruiting

Telemedical Assistance in Automatic Titration of Oxygen for Intensive Care Patients (Smartassistant)

Pneumonia | Interstitial Lung Disease | Chronic Obstructive Lung Disease | Obesity Hypoventilation Syndrome (OHS)

Latvia
Instituto de fertilidad humana, InSer
University of Alabama at Birmingham; Colmédicos S.A.S.; ABAD Laboratorio

Recruiting

Phenotype and Epidemiology of the Polycystic Ovary Syndrome (PCOS) in Colombia (PEP - Colombia) Study. (PEP-Colombia)

Endocrine System Diseases | Polycystic Ovary Syndrome | Hyperandrogenism

Colombia
University Hospital Muenster

Recruiting

Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.

Sepsis | Pre-Eclampsia | Adiposity | Microscopic Polyangiitis | Granulomatosis With Polyangiitis | SIRS | Procalcitonin

Germany
Molnlycke Health Care AB

Recruiting

A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.

Diabetic Foot Ulcer | Wound; Foot | Venous Leg Ulcer | Wounds | Wound of Skin | Wound Leg

United States
Clinique Ovo

Recruiting

Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients (HIP)

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Canada
Kliniken Beelitz GmbH

Recruiting

Evaluation of the Efficacy of a Two-week EMST on Dysphagia in Parkinsonian Patients (EMST-PS)

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy

Germany
Kliniken Beelitz GmbH
Hannover Medical School; University Hospital Muenster; Medical University Innsbruck and other collaborators

Recruiting

Systematic Assessment of Laryngopharyngeal Function in Patients With MSA, PD, and 4repeat Tauopathies (FEEMSA)

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy

Germany, Austria, Israel, Italy, Poland, Spain, Japan, Korea, Republic of
University of Virginia
Waterloo Foundation

Recruiting

Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess? (CBS009)

Polycystic Ovary Syndrome | Puberty Disorders | Ovulation Disorder

United States
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors (LIBRETTO-121)

Soft Tissue Sarcoma | Medullary Thyroid Cancer | Papillary Thyroid Cancer | Infantile Fibrosarcoma | Infantile Myofibromatosis

United States, Australia, Japan, Canada, Germany, Korea, Republic of, France, Spain, United Kingdom, Denmark, Italy
Shanghai Mental Health Center

Recruiting

The China Longitudinal Aging Study of Cognitive Impairment

Depression | Anxiety | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia With Lewy Bodies | Dementia Frontal

China

Clinical Trials on Substrate Metabolism

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Mongolia

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Rare Diseases

Drug Interventions

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