Clinical Trials on Surgical Site Infections in South Africa

Total 7083 results

The Aurum Institute NPC
Johns Hopkins University; Weill Medical College of Cornell University; University...

Recruiting

Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV (DOLPHIN Moms)

Pregnancy | HIV Seropositivity | Tuberculosis Infection

South Africa
BioVersys AG
TASK Applied Science

Completed

Pharmacokinetics of Ethionamide and Ethionamide Sulfoxide in Patients Established on Treatment for Tuberculosis.

Tuberculosis, Pulmonary

South Africa
Michael Hoelscher
Quintiles, Inc.; German Federal Ministry of Education and Research; Parexel; European... and other collaborators

Completed

Early Bactericidal Activity (EBA) of SQ109 in Adult Subjects With Pulmonary TB (SQ109EBA)

Tuberculosis, Pulmonary

South Africa
University of Illinois at Chicago
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA (IMARA-SA pilot)

Hiv | Sexually Transmitted Infection

South Africa
GlaxoSmithKline
Click-TB Consortium

Recruiting

Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis

Tuberculosis

South Africa
BioMérieux

Completed

Validating the Use of Blood Transcriptomic Signatures for the Diagnosis of Active Pulmonary Tuberculosis (ISIT-TB)

TUBERCULOSIS, PULMONARY

South Africa
University of Cape Town
National Institute of Allergy and Infectious Diseases (NIAID)

Unknown

Rapid Diagnosis of Pulmonary Tuberculosis

Tuberculosis

South Africa
Code Pharma

Recruiting

Phase IIa Randomized Placebo Controlled Clinical Study of Codivir in Hospitalized Patients With Moderate COVID-19

COVID-19

South Africa
University College, London
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis

South Africa
Johns Hopkins University
University of Cape Town

Completed

Assessing PA-824 for Tuberculosis (the APT Trial)

Pulmonary Tuberculosis

South Africa
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Prevent TB: Choice Architecture for TPT Delivery

HIV/AIDS | Tuberculosis

South Africa
University of California, Los Angeles
University of Cape Town

Active, not recruiting

Evaluation of Pre-Exposure Prophylaxis (PrEP) in Pregnant and Breastfeeding Women (PrEP-PP)

HIV-I Infection

South Africa
GlaxoSmithKline

Completed

An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis

Tuberculosis

South Africa
Radboud University Medical Center
European and Developing Countries Clinical Trials Partnership (EDCTP); Department... and other collaborators

Completed

Safety, Tolerability, Extended Early Bactericidal Activity and PK of Higher Doses Rifampicin in Adults With Pulmonary TB (HR1)

Pulmonary Tuberculosis (TB)

South Africa
Find
University of Cape Town; Universidad Peruana Cayetano Heredia

Unknown

Performance Evaluation of TB Breath- and Cough-testing Platforms

Diagnoses Diseases | Pulmonary TB

South Africa
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Pulmonary Tuberculoses | Other Specified Pulmonary Tuberculosis

South Africa
New York State Psychiatric Institute
National Institute of Allergy and Infectious Diseases (NIAID); Columbia University and other collaborators

Recruiting

Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South Africa

Depression | Tuberculosis

South Africa
University of Cape Town
University of Zurich; University of Bern; University of Stellenbosch; University...

Recruiting

Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion (StatinTB)

Tuberculosis, Pulmonary

South Africa
International AIDS Vaccine Initiative
Targeted Genetics Corporation

Completed

Safety and Immunogenicity Study of tgAAC09, an HIV Vaccine in an Adeno-associated Virus (AAV) Capsid (TGC14F)

HIV Infections | Human Immunodeficiency Virus Infections

Uganda, South Africa, Zambia
University of Maryland, Baltimore
Patient-Centered Outcomes Research Institute; McMaster University

Active, not recruiting

Pre-operative Alcohol Skin Solutions in Fractured Extremities (PREPARE)

Surgical Site Infection | Pelvic Fracture | Unplanned Fracture-Related Reoperation | Open Appendicular Fracture | Closed Lower Extremity Fracture

United States, Canada
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University Hospital... and other collaborators

Not yet recruiting

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis (TSELiOT)

Drug-resistant Tuberculosis | Cost-Benefit Analysis | HIV Coinfection

South Africa
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults (HVTN 097)

HIV Infection

South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

PK Study of Rifampicin Interactions With DMPA and Efavirenz in TB (PRIDE-HT)

Tuberculosis | HIV-1 Infection

South Africa, Zimbabwe, Botswana, Kenya
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Completed

HIV & Drug Abuse Prevention for South African Men

Substance-Related Disorders | Alcoholism | Human Immunodeficiency Virus

South Africa
Vanderbilt University Medical Center
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

The Risk of HIV Acquisition Among Traditional Healers in South Africa

HIV Infections

South Africa
Willem Daniel Francois Venter
Medical Research Council, South Africa

Completed

Evaluation of Low-dose Darunavir in a Switch Study (DRV)

HIV Infections

South Africa
Barbara Ensoli, MD
Italian Ministry of Foreign Affairs - General Direction for Cooperation and...

Completed

A Phase Il of a Therapeutic, Recombinant, Biologically Active HIV-1 Tat Protein Vaccine in HIV-Infected, Anti-Tat Negative, ARV-Treated Adult Volunteers (ISS T-003)

HIV Infections

South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Voluntary HIV Counseling, Testing, and Medication for Pregnant Women to Prevent Mother-to-Child HIV Transmission

HIV Infections

South Africa
Shabir Madhi

Not yet recruiting

Pertussis Vaccination Among HIV-infected and HIV-uninfected Pregnant Women

dTap Vaccine

South Africa
Istituto Superiore di Sanità

Recruiting

Extended Follow-Up of the ISS T-003 Trial Volunteers (ISS T-003 EF-UP2020) (T003EFUP2020)

HIV Infections

South Africa
Johns Hopkins University
University of Cape Town

Terminated

Helping HIV Infected Patients in South Africa Adhere to Drug Regimens

HIV Infections

South Africa
University of Witwatersrand, South Africa
Bill and Melinda Gates Foundation; ViiV Healthcare

Active, not recruiting

Acceptability and Feasibility of Injectable Cabotegravir Pre-exposure Prophylaxis (PrEP) Versus Oral PrEP in Routine Care up to 15 Months in Private Pharmacies in South Africa (AXIS)

HIV Infections

South Africa
Gritstone bio, Inc.

Completed

Study of Self-Amplifying Messenger Ribonucleic Acid (samRNA) Vaccines Against COVID-19 in Healthy Adults and People Living With Human Immunodeficiency Virus (HIV)

COVID-19 | SARS-CoV-2

South Africa
Boston University
United States Agency for International Development (USAID)

Withdrawn

Impact of Anti-HIV Treatment on Labor Productivity and Costs in South Africa

HIV Infections

South Africa
Barbara Ensoli, MD, PhD
Italian Ministry of Foreign Affairs - General Direction for Cooperation and...

Completed

A Roll-over Observational Study for the Extended Follow-up of the Volunteers of the ISS T-003 Trial (ISST-003EF-UP)

HIV Infections

South Africa
National Institute for Communicable Diseases, South...
Centers for Disease Control and Prevention; Fogarty International Center of... and other collaborators

Active, not recruiting

Household Study of COVID-19, Influenza and RSV Burden, Transmission Dynamics and Viral Interaction in South Africa (PHIRST-C)

Influenza | SARS-CoV-2 Infection | Respiratory Syncytial Virus (RSV)

South Africa
Duke University
National Institute of Mental Health (NIMH); Florida State University; University... and other collaborators

Completed

Piloting a Smartphone App to Improve Treatment Adherence Among South African Adolescents Living With HIV

HIV Infections | Adolescent Behavior

South Africa
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Treatment Options for Protease Inhibitor-exposed Children (NEVEREST-III)

HIV Infections | HIV/AIDS

South Africa
University of Oxford
University of Cape Town

Completed

A Study of MVA85A, in Asymptomatic Volunteers Infected With TB, HIV or Both

HIV Infections | TB

South Africa
Aeras
Crucell Holland BV

Completed

Safety and Immunogenicity of AERAS-402 in HIV-infected, Bacillus Calmette-Guerin (BCG)-Vaccinated Adults

HIV Infections | Tuberculosis

South Africa
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); Human Sciences...

Recruiting

ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa (ThiPhiSA)

Tuberculosis

South Africa
Biofabri, S.L
South African Tuberculosis Vaccine Initiative; TuBerculosis Vaccine Initiative and other collaborators

Completed

Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African Neonates (MTBVAC-03)

Tuberculosis

South Africa
Biofabri, S.L
South African Tuberculosis Vaccine Initiative; TuBerculosis Vaccine Initiative and other collaborators

Completed

Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adults (MTBVAC-Ph1b)

Tuberculosis

South Africa
FHI 360
Foundation for Professional Development; Future Families

Completed

Evaluation of an Integrated Economic Strengthening and HIV Prevention Program for Vulnerable Youth in South Africa (ASPIRES)

HIV Infections | HIV

South Africa
University of Pennsylvania
Aurum Institute; University of Witwatersrand, South Africa

Completed

Behavioural Text Messages to Improve Retention in Care in South Africa

HIV/AIDS

South Africa
Vanderbilt University Medical Center
University of Cape Town

Completed

CareConekta: A Pilot Study of a Smartphone App in South Africa

HIV/AIDS

South Africa
Population Council

Active, not recruiting

A Crossover Adherence and Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention

HIV Infections

South Africa
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Evaluating Safety and Immune Response to the HIV-1 CH505 Transmitted/Founder gp120 Adjuvanted With GLA-SE in Healthy, HIV-exposed Uninfected Infants (HVTN 135)

HIV Infections

South Africa
University of Witwatersrand, South Africa

Completed

Efficacy of Influenza Vaccine in HIV Infected Adults

HIV Infections | HIV | Influenza | Vaccination

South Africa
Harvard School of Public Health (HSPH)
University of Heidelberg Medical Center; University of Witwatersrand, South...

Unknown

Home HIV Testing for Older Adults in South Africa (Test@Home)

HIV Infections | Knowledge, Attitudes, Practice

South Africa

Clinical Trials on Surgical Site Infections in South Africa

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