Clinical Trials on Systemic Inflammation

Total 191166 results

AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; Janssen... and other collaborators

Recruiting

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Plasmablastic Lymphoma | Ann Arbor Stage I Diffuse Large B-Cell Lymphoma | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma | Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma

United States
University of Virginia
Waterloo Foundation

Recruiting

Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess? (CBS009)

Polycystic Ovary Syndrome | Puberty Disorders | Ovulation Disorder

United States
Udai Kammula

Recruiting

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Sarcoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Neuroendocrine Tumors | Mesothelioma | Merkel Cell Carcinoma | Microsatellite Instability | Squamous Cell Cancer | Mismatch Repair Deficiency

United States
Frederic Amant
Kom Op Tegen Kanker; FWO Research Fund Flanders

Recruiting

FUlvestrant in Gynecological Cancers That Are Potentially Hormone Sensitive: the FUCHSia Study (FUCHSia)

Endometrial Cancer | Endometrial Stromal Sarcoma | Sex Cord Stromal Tumor | Adenosarcoma of Uterus | Leiomyosarcoma Uterus | Serous Ovarian Tumor

Belgium
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Minimal Residual Disease | Hematopoietic Cell Transplantation Recipient | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Bevacizumab in Ovarian Cancer Patients With Disease at Second-Look Surgery

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer | Malignant Neoplasms of Female Genital Organs

United States
Karolinska Institutet
Karolinska University Hospital; Peking University

Recruiting

Acupuncture or Metformin for Insulin Resistance in Women With PCOS (PIAII)

Polycystic Ovary Syndrome | Hyperandrogenism | Insulin Resistance

Sweden, China
University of Virginia

Recruiting

Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

Obesity | Polycystic Ovary Syndrome | Hyperandrogenemia

United States
University of Waterloo

Completed

MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults.

Cardiovascular Diseases | Stroke | Kidney Diseases | Hypertension | Obesity | Diabetes | Cancer | Arthritis | Frailty | Osteoporosis | Chronic Lung Disease | Congestive Heart Failure

Canada
Eunice Kennedy Shriver National Institute of Child...

Completed

Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia (CAH)

United States
Genmab
AbbVie

Active, not recruiting

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma (EPCORE™ NHL-1)

Small Lymphocytic Lymphoma (SLL) | DLBCL | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | MCL | Marginal Zone Lymphoma (MZL) | High-grade B-cell Lymphoma (HGBCL) | FL

Korea, Republic of, United States, Australia, Singapore, Netherlands, Sweden, France, Finland, United Kingdom, Spain, Germany, Denmark, Italy, Poland, Canada
Neurocrine Biosciences

Active, not recruiting

Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst)

Congenital Adrenal Hyperplasia

United States, Spain, Belgium, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Israel, Italy, Netherlands, Poland, Portugal, Serbia, Sweden, United Kingdom
University Medical Center Groningen
VHL Alliance

Completed

Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease (VHLimage)

Renal Cell Carcinoma | Von Hippel-Lindau Disease | Pheochromocytoma | Pancreatic Neuroendocrine Tumor | Hemangioblastoma

Netherlands
Memorial Sloan Kettering Cancer Center
Context Therapeutics Inc.

Active, not recruiting

A Study of Onapristone ER Alone Or In Combination With Anastrozole in Gynecologic Cancers That Respond to Progesterone

Granulosa Cell Ovarian Cancer | Low Grade Serous Ovarian/ Primary Peritoneal Cancer | Endometrioid Endometrial Cancer

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin UK, Ltd.

Completed

A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma

Multiple Myeloma | Chronic Lymphocytic Leukaemia | B-cell Non-Hodgkin's Lymphoma

United Kingdom
Vanderbilt University Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Brigham... and other collaborators

Suspended

Optimal Management of HIV Infected Adults at Risk for Kidney Complications in Nigeria

Kidney Diseases | HIV/AIDS | Albuminuria | Genetic Predisposition

Nigeria
Renalytix AI, Inc.

Active, not recruiting

Prospective Decision Impact Clinical Utility Trial of KidneyIntelX

Chronic Kidney Diseases | Diabetic Kidney Disease | Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 2 | Chronic Kidney Disease Stage 1

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy

Ovarian Cancer | Fallopian Tube Cancer | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States
Diurnal Limited

Completed

Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia (CONnECT)

Congenital Adrenal Hyperplasia

France, United States, Japan
Karolinska University Hospital
Karolinska Institutet

Withdrawn

Hepatitis B in Cystic Fibrosis and Latent Tuberculosis Respectively

Hepatitis B | Hepatitis A | Tuberculosis | Cystic Fibrosis

Sweden
NeoImmuneTech
Merck Sharp & Dohme LLC

Active, not recruiting

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (KEYNOTE A60)

Small Cell Lung Cancer | Pancreatic Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Microsatellite Stable Colorectal Cancer | Any Advanced Solid Tumors

United States
Verastem, Inc.
GOG Foundation; European Network of Gynaecological Oncological Trial Groups...

Active, not recruiting

A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation (RAMP 201)

Ovarian Cancer | Low Grade Ovarian Serous Adenocarcinoma

Spain, United States, Belgium, United Kingdom, France, Canada, Italy
AstraZeneca
Merck Sharp & Dohme LLC; GOG Foundation; Myriad Genetic Laboratories, Inc.

Active, not recruiting

Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy. (SOLO-1)

Advanced Ovarian Cancer | Newly Diagnosed | FIGO Stage III-IV | Partial Response | Complete Response | BRCA Mutation | First Line Platinum Chemotherapy

Korea, Republic of, France, Italy, United States, Israel, Canada, China, Brazil, United Kingdom, Poland, Australia, Japan, Netherlands, Russian Federation, Spain
Hospices Civils de Lyon

Completed

Fertility and Pregnancy in Patients With Classic Congenital Adrenal Hyperplasia (FERTI-HCS)

Classic Congenital Adrenal Hyperplasia

France
BeiGene

Completed

Study of the Efficacy, Safety and Pharmacokinetics of Pamiparib (BGB-290) in Participants With Advanced Solid Tumors

Triple Negative Breast Cancer | Advanced High-grade Ovarian Cancer

China
InnoCon Medical
Odense University Hospital; Aarhus University Hospital; Herlev Hospital

Completed

Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)

Urinary Incontinence | Fecal Incontinence | Urge Incontinence | Urinary Incontinence, Urge | Nocturia | Urinary Frequency More Than Once at Night | Incontinence, Nighttime Urinary | Bowel Disorders Functional

Denmark
Daxor Corporation
Oregon Health and Science University; Stern Cardiovascular Foundation, Inc.

Completed

BVA-200 vs BVA-100 Validation Study

Heart Failure | Kidney Diseases | Diabetes | Thyroid Diseases | Anemia | Trauma | High Blood Pressure | High Cholesterol | Other Disease | Clotting Disorder

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Frequency of Cachexia in Ambulatory Cancer Patients and Psychological Burden in Patients and Their Primary Caregivers

Advanced Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Recurrent Plasma Cell Myeloma | Caregiver | Recurrent Leukemia

United States
Spruce Biosciences

Active, not recruiting

A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH

Congenital Adrenal Hyperplasia

United States, Australia, Brazil, Canada, Denmark, Estonia, Germany, Ireland, Italy, Korea, Republic of, Latvia, Lithuania, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, Turkey, United Kingdom
Center for International Blood and Marrow Transplant...
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702) (BMT CTN 1702)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Sickle Cell Disease | Non-hodgkin Lymphoma | Acquired Aplastic Anemia

United States
Ferring Pharmaceuticals

Completed

Evaluation of Overall Compliance and Duration of Zomacton® Treatment With the Zomajet® Needle-free Device (ZOMAJET)

Turner's Syndrome | Human Growth Hormone Deficiency

France
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Venetoclax and Romidepsin in Treating Patients With Recurrent or Refractory Mature T-Cell Lymphoma

Anaplastic Large Cell Lymphoma | Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma

United States
Tan Tock Seng Hospital

Completed

Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot

Plantar Fasciitis | Achilles Tendinopathy | Insertional Achilles Tendinopathy | Metatarsalgia | Pes Cavus | Subtle Cavus Foot | Mechanical Foot Pains | Strain of Peroneal Tendon | Pes Cavus, Bilateral | Pes Cavovarus

Singapore
Boston Children's Hospital
United States Department of Defense; Stanford University

Active, not recruiting

Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score (TEAMMATE)

Chronic Kidney Diseases | Post-transplant Lymphoproliferative Disorder | Immunosuppression | Pediatric Heart Transplantation | Cardiac Allograft Vasculopathy | Heart Transplant Failure and Rejection | Heart Transplant Infection

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Lenalidomide Therapy After Chemotherapy & Stem Cell Transplant in Treating Chemotherapy Resistan Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma | Anaplastic Large Cell Lymphoma, ALK-Negative | Recurrent Anaplastic Large Cell Lymphoma

United States
Astellas Pharma Inc
Vical

Completed

Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Canadian Cancer Trials Group
National Cancer Institute (NCI); Cancer Research UK; Grupo Español de Investigación... and other collaborators

Completed

Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer | Metastatic Cancer

Canada, Spain, United States, United Kingdom
Jacobs University Bremen gGmbH
Dr. Becker Hospital Group; Dr. Becker Klinik Möhnesee; Dr. Becker Burg-Klinik... and other collaborators

Completed

Feasibility and Benefits of Digital Services During the COVID19 Pandemic (AnhandCOV19)

Anxiety | Communication | Psychological Distress | Health Risk Behaviors | Healthy Lifestyle | Psychological Adjustment | Psychological Stress | Psychological Disorder | Behavior, Health | Psychological Disease | Psychosomatic Disorder | Psychological Adaptation | Health Care Seeking Behavior | Psychological Disability and other conditions

Germany
Bezmialem Vakif University

Completed

Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia

Hematuria | Retention, Urinary | Operative Bleeding | Blood Transfusion Complication

Turkey
University of Oxford
Intensive Care National Audit & Research Centre

Active, not recruiting

Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales (OPTIC-19)

Myocardial Infarction | Heart Failure | Stroke | Critical Illness | Covid19 | Renal Failure | Deep Vein Thrombosis | Pulmonary Embolism

United Kingdom
Air Liquide Santé International

Completed

Study Evaluating Telemonitoring and Experimentation in Telemedicine for the Improvement of Healthcare Pathways (ETAPES Program) Compared to Standard of Care in Patients With Chronic Respiratory Failure Receiving Non-invasive Home Ventilation (e-VENT)

Chronic Obstructive Pulmonary Disease (COPD) | Obesity Hypoventilation Syndrome (OHS) | Chronic Respiratory Failure With Hypercapnia

France
Eli Lilly and Company
Loxo Oncology, Inc.

Active, not recruiting

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

Lymphoma, Non-Hodgkin | B-cell Lymphoma | Multiple Myeloma | Lymphoma, Mantle-Cell | Waldenstrom Macroglobulinemia | Leukemia, Lymphocytic, Chronic, B-Cell | Lymphoma, B-cell Marginal Zone

United States, France, Poland, Italy
Rigshospitalet, Denmark

Active, not recruiting

Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma

Quality of Life | Pain | Oropharynx Cancer | Human Papilloma Virus | Swallowing Disorder | Saliva Altered

Denmark
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood NK Cells, Rituximab, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma

Mantle Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Indolent Adult Non-Hodgkin Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Recurrent Indolent Adult Non-Hodgkin Lymphoma

United States
Florida International University
Nicklaus Children's Hospital f/k/a Miami Children's Hospital; Cornelia T. Bailey...

Completed

Drug Sensitivity and Mutation Profiling

Osteosarcoma | Ewing Sarcoma | Rhabdomyosarcoma | Wilms Tumor | Sarcoma, Spindle Cell | Sarcoma Rhabdoid | Childhood Sarcoma of Soft Tissue

United States
Sutro Biopharma, Inc.

Active, not recruiting

Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies

Follicular Lymphoma | B-cell Lymphoma | Multiple Myeloma | Mantle Cell Lymphoma | Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | Indolent Lymphoma | B Cells--Tumors

United States
ProQR Therapeutics

Active, not recruiting

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Netherlands, United Kingdom, Germany
Nasser Hanna, M.D.
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Terminated

Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors

Genital Neoplasms, Female | Testicular Neoplasms | Genital Neoplasms, Male | Ovarian Neoplasms | Mediastinal Neoplasms | Germ Cell Neoplasms | Non Seminomatous Germ Cell Tumors

United States
Kaiser Permanente

Active, not recruiting

Validating the Use of a Subjectively Reported Sleep Vital Sign (SSVS)

Insomnia | Obstructive Sleep Apnea (OSA) | Restless Leg Syndrome (RLS) | Hypersomnia Type; Sleep Disorder | Shift Work Sleep Disorders

United States
Catalysis SL

Completed

Evaluation of Ocoxin-Viusid® in Advanced or Metastatic Ovarian Epithelial Cancer

Urogenital Neoplasms | Carcinoma | Neoplasms, Glandular and Epithelial | Endocrine System Diseases | Ovarian Diseases | Adnexal Diseases | Gonadal Disorders | Genital Diseases, Female | Ovarian Neoplasm | Female Urogenital Diseases | Endocrine Gland Neoplasm | Female Urogenital Diseases and Pregnancy Complications and other conditions

Cuba

Clinical Trials on Systemic Inflammation

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CROs in Congo

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