Clinical Trials on Systemic Mast Cell Activation

Total 14644 results

Novo Nordisk A/S

Completed

Barriers to MASLD Management in Europe: Findings From a Multidisciplinary HCP-survey (BARRIERS-MASLD)

Non-alcoholic Steatohepatitis (MASH) | Non-alcoholic Fatty Liver Disease (MASLD)

India
Peking Union Medical College Hospital

Completed

The Investigation of Public Awareness of Core Stroke Symptoms (IPACSS)

Stroke | Health Knowledge, Attitudes, Practice | Awareness | Core Symptoms | FAST

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Germany, Italy
Assiut University

Unknown

Role of Thymus-And Activation-Regulated Chemokine (TARC) In Diagnosis Of Allergic Bronchopulmonary Aspergillosis

Thymus and Activation Regulated Chemokine
US Department of Veterans Affairs

Completed

Survey of ColoRectal Cancer Education and Environment Needs (SCREEN)

Colorectal Neoplasms | Patient Compliance | Mass Screening

United States
University of California, San Francisco
Yale University; Rune Labs

Recruiting

Understanding Motivation in Parkinson's Patients Through Neurophysiology (MPPN)

Parkinson Disease | Motivation | Deep Brain Stimulation

United States
Dr. S.S. Michel Clinic

Completed

Pituitary Gland Enlargement Was First Diagnosed by Optical Coherence Tomography (OCT) (OCT)

Diagnoses Disease | Pituitary Mass

Canada
Freie Universität Berlin
Boehringer Ingelheim

Completed

Increasing Vitamin Intake and Physical Activity (BIV-BIA)

Heart Diseases | Diabetes Mellitus, Type 2 | Motivation | Behavior

Germany
Antonio Arroyo Sebastian

Unknown

Peripheral Parenteral Nutrition vs Conventional Fluid in Colorectal Resection in ERAS

Colon Cancer | Parenteral Nutrition | Fast-track

Spain
Zhongnan Hospital

Unknown

Circulating Tumor Cell Capture for Early Diagnosis and Postoperative Tumor Recurrence Monitoring of Liver Cancer

Circulating Tumor Cell

China
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

Retrospective Study: Efficacy and Safety of Chlorambucil + Rituximab in CLL Patients

Elderly Patients | Small Lymphocytic Lymphoma | CLL | B-cell | Untreated B-CLL

Italy
University of Bridgeport

Unknown

Short-term Effects of Passiflora and Meditation on Blood Pressure and Heart Rate

Blood Pressure | Heart Rate Fast
Second Affiliated Hospital of Nanchang University
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

Almonertinib With Bevacizumab for EGFR-Mutant NSCLC Patients With Leptomeningeal Metastasis (ATTRACT)

NSCLC | EGFR Activating Mutation | Leptomeningeal Metastasis

China
The Cleveland Clinic
Case Western Reserve University

Completed

Accuracy of the Apple Watch Series 4 for Detection of Heart Rhythm: A Pilot Study

Heart Rate Fast | Heart Rate Low

United States
University of Pennsylvania
National Institute of Drug Abuse; The Wistar Institute; Ho Chi Minh City CDC; Institute...

Recruiting

Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1 (AMOHI-1)

Inflammation | Opioid-use Disorder | HIV-1-infection | Immune Activation | Buprenorphine | Methadone | Naltrexone | Antiretroviral Treatment

United States, Vietnam
Rain Oncology Inc

Terminated

Study of Tarloxotinib in Pts With NSCLC (EGFR Exon 20 Insertion, HER2-activating Mutations) & Other Solid Tumors With NRG1/ERBB Gene Fusions (RAIN)

NSCLC Stage IIIB | NSCLC, Recurrent | NRG1 Fusion | EGFR Exon 20 Insertion Mutation | NSCLC, Stage IIIC | NSCLC, Stage IV | HER2-activating Mutation | ERBB Fusion

United States, Canada, Hong Kong
Universidad Miguel Hernandez de Elche
Puerta de Hierro University Hospital; Ministerio de Ciencia e Innovación, Spain

Recruiting

Physical Activity and Motivation in Colorectal Cancer Patients

Quality of Life | Colorectal Cancer | Motivation | Physical Exercise | Side Effect

Spain
Hellenic Institute for the Study of Sepsis

Completed

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction (ESCAPE)

Virus Diseases | COVID-19 | Corona Virus Infection | Macrophage Activation Syndrome

Greece
Blueprint Medicines Corporation

Terminated

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Neoplasms | Respiratory Tract Diseases | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | Non Small Cell Lung... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Burkitt Lymphoma | Secondary... and other conditions

United States
Samsung Medical Center

Not yet recruiting

Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam

Respiratory Disease | Tracheal Stenosis | Endobronchial Mass
Memorial Sloan Kettering Cancer Center

Completed

Functional Imaging of Cerebellar Mutism Syndrome

Brain Mass

United States
University Hospital Birmingham
Ortho Biotech, Inc.; Gambro Renal Products, Inc.

Completed

European Trial of Free Light Chain Removal by Extended Haemodialysis in Cast Nephropathy (EuLITE)

Multiple Myeloma | Kidney Failure | Cast Nephropathy

United Kingdom
Arbeitsgemeinschaft medikamentoese Tumortherapie

Completed

Rituximab Plus Lenalidomide in Patients With Mucosa Associated Lymphoid Tissue

Lymphoma of the Mucosa Associated Lymphoid Tissue (MALT)

Austria
Arcispedale Santa Maria Nuova-IRCCS

Unknown

Kidney Therapy for Free Light Chain Removal in Patients With Multiple Myeloma & Cast Nephropathy (KEEPER)

Multiple Myeloma | Acute Kidney Injury | Cast Nephropathy

Italy
Bispebjerg Hospital

Completed

Distribution of Nutrient Derived Amino Acids

Diet Modification | Sarcopenia | Protein Intake | Protein Synthesis | Muscle Mass | Protein Breakdown

Denmark
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Nutritional Supplementation in Reducing Complications in Patients With Locally Advanced Esophageal Cancer Undergoing Chemotherapy, Radiation Therapy, and/or Surgery

Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8 | Pathologic Stage III Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage III Esophageal Squamous Cell Carcinoma AJCC v8 | Pathologic Stage IIIA Esophageal Adenocarcinoma... and other conditions

United States
Gilead Sciences

Completed

Ph I/II Study of Subcutaneously Administered Veltuzumab (hA20) in NHL and CLL

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Non-Hodgkin | Lymphoma, Low-Grade | Lymphoma, Small Lymphocytic | Leukemia, Prolymphocytic | NHL | CLL | Leukemia, Lymphocytic, Chronic | Lymphoma, Intermediate-Grade | Lymphoma, Large-Cell | Lymphoma, Mixed-Cell | Lymphoma, Small-Cell | Leukemia, B-Cell, Chronic | Leukemia... and other conditions

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Novartis Pharmaceuticals

Completed

Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma

Mantle Cell Lymphoma | Gray Zone Lymphoma | Hodgkin's Disease | CD20+, B-cell Lymphomas | Non-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL) | Transformed Lymphoma/DLBCL/PMBCL

United States
AstraZeneca
CLL Consortium

Completed

AZD6738 First Time in Patient Multiple Ascending Dose Study

B Cell Lymphomas | 11q-deleted Relapsed/Refractory Chronic Lymphocytic Leukaemia (CLL), | Prolymphocytic Leukaemia (PLL)

United States
National Cancer Institute (NCI)

Completed

Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy

HIV Infection | Clear Cell Renal Cell Carcinoma | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States
Maltepe University
Hisar Intercontinental Hospital; Pendik State Hospital

Completed

Pediatric Inguinal Hernia Repair: Are Muscle Relaxants Necessary? Endotracheal Intubation vs Laryngeal Mask Airway

Endotracheal Intubation | Inguinal Hernia | Laryngeal Mask | Muscle Relaxants

Turkey
University of Medicine and Pharmacy "Victor Babes...

Not yet recruiting

Physical Therapy Students: Well-being

Anxiety State | Motivation | Life Stress | Sleep, Inadequate
Maastricht University
Aristotle University Of Thessaloniki; P1vital Products LTD.; Biotrial; University... and other collaborators

Completed

Validating Reward-related Biomarkers (RTOC) (RTOC)

Depression | Schizophrenia | Motivation | Anhedonia, Physical | Anhedonia, Social | Negative Symptoms With Primary Psychotic Disorder

Germany, Greece, Netherlands, Spain
Akero Therapeutics, Inc

Recruiting

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis | MASH With Fibrosis

United States, Canada, Puerto Rico, Australia, India, France, Italy, Poland, Spain
Kuopio University Hospital
University of Eastern Finland

Completed

Identification of Arrhythmias With One-time ECG

Atrial Fibrillation | Heart Rate Fast | Heart Rate Low

Finland
Peloton Therapeutics, Inc., a subsidiary of Merck...

Active, not recruiting

A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004)

VHL - Von Hippel-Lindau Syndrome | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL-Associated Renal Cell Carcinoma | VHL-Associated Clear Cell Renal Cell Carcinoma

United States, Denmark, United Kingdom, France
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

Follicular Lymphoma | B-cell Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Large B-cell Lymphoma | Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

United States
Hospices Civils de Lyon

Not yet recruiting

Multidimensional Assessment of Quality of Life, Social and Professional Life and Care Utilization in Patients With Diffuse Large Cell B-cell Lymphoma Treated With CAR-T Cells (QUALITOP CAR-T)

Diffuse Large B-cell Lymphoma (DLBCL) | CAR-T Cells Treatment

France
Sunil Patel

Completed

Smart Phone App for COLOnoscopic PREParation (COLOPREP)

Colonoscopy | Mass Screening | Colorectal Cancer Screening

Canada
TYK Medicines, Inc

Recruiting

TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases

NSCLC | Brain Metastases | EGFR Activating Mutation

China
Athenex, Inc.

Recruiting

Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies (ANCHOR2)

B-cell Lymphoma | CLL/SLL | ALL, Childhood | DLBCL - Diffuse Large B Cell Lymphoma | B-cell Leukemia | NHL, Relapsed, Adult | ALL, Adult B Cell

United States
Jonsson Comprehensive Cancer Center
Novartis Pharmaceuticals

Withdrawn

TCR Genetically Engineered PBMC and PBSC After Melphalan Conditioning Regimen in Treating Participants With Relapsed and Refractory Multiple Myeloma (NYSCT MM)

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | HLA-A*0201 Positive Cells Present | NY-ESO-1 Positive Tumor Cells Present

United States
Jun Zhu
Peking University First Hospital; Peking University People's Hospital; Peking... and other collaborators

Withdrawn

A Study of Treatment ALK(+) Systemic Anaplastic Large Cell Lymphoma With Crizotinib

Systemic Anaplastic Large-Cell Lymphoma

China
Peloton Therapeutics, Inc., a subsidiary of Merck...
National Institutes of Health (NIH)

Completed

PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma | Von Hippel-Lindau Disease | Clear Cell RCC | ccRCC | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL | Von Hippel | Von Hippel's Disease | Von Hippel-Lindau Syndrome, Modifiers of

United States
National Health Research Institutes, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital; Taipei Veterans General... and other collaborators

Unknown

The Emergence of RAS Mutations in Metastatic Colorectal Cancer Patients Receiving Cetuximab Treatment

Colorectal Cancer | Drug Resistance | Mass Spectrometry | RAS-RAF Pathway Deregulation

Taiwan
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Safety and Efficacy of T8 on Treating Chronic Abnormal Immune Activation in HIV/AIDS Patients

Chronic Abnormal Immune Activation in HIV/AIDS

China
M.D. Anderson Cancer Center

Completed

Comparison of a Novel 22-gauge Core Biopsy Needle

Malignant Neoplasm of Pancreas | Solid Pancreatic Mass Lesions

United States
Synthekine

Recruiting

Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies

Follicular Lymphoma | Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | NHL | CLL/SLL | Large B-cell Lymphoma | Indolent B-Cell Non-Hodgkin Lymphoma

United States
Institut Català d'Oncologia
University of Dundee; University Rovira i Virgili; University of Barcelona

Unknown

SMS Messaging as a Tool to Improve Cancer Screening Programs (M-TICS)

Breast Cancer | Colorectal Cancer | Mass Screening

Clinical Trials on Systemic Mast Cell Activation

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