Clinical Trials on TTM

Total 114 results

Tzu-Ting Huang

Completed

Non-pharmacological Interventions on Cognitive Functions in Older People With Mild Cognitive Impairment

Physical Activity | Mild Cognitive Impairment | Cognitive Rehabilitation | TTM
Taris Biomedical LLC
Bristol-Myers Squibb

Terminated

Safety and Tolerability of TAR-200 and Nivolumab in Subjects With Muscle-Invasive Bladder Cancer

Bladder Cancer TNM Staging Primary Tumor (T) T2 | Bladder Cancer TNM Staging Primary Tumor (T) T2A | Bladder Cancer TNM Staging Primary Tumor (T) T2B | Bladder Cancer TNM Staging Primary Tumor (T) T3 | Bladder Cancer TNM Staging Primary Tumor (T) T3A | Bladder Cancer TNM Staging Primary Tumor... and other conditions

United States
Konstantinos Kouladouros

Recruiting

Retrospective Analysis of TEM and TEM-ESD for the Treatment of Rectal Adenomas and Early Rectal Cancer

Perioperative and Long-term Outcomes of TEM and TEM-ESD

Germany
Catharina Ziekenhuis Eindhoven

Recruiting

Therapeutic Oncolytic Monitoring as a Tool for Effective Exposure to 5-FU in Patients With Locally Advanced, Resectable Gastric or Gastro-oesophageal Junction Cancer Treated With Perioperative FLOT (THOMAS FU FLOT)

TDM of 5-FU | Pharmacokinetic Observational Study

Netherlands
Cancer Institute and Hospital, Chinese Academy...
Tianjin Medical University Cancer Institute and Hospital; Sichuan Cancer Hospital...

Unknown

Efficacy of Intensity Modulated Radiation Therapy After Surgery in Early Stage of Esophageal Carcinoma; (IMRT)

Esophageal Neoplasm | Esophageal Cancer TNM Staging Primary Tumor (T) T3 | Esophageal Cancer TNM Staging Primary Tumor (T) T2 | Esophageal Cancer TNM Staging Regional Lymph Nodes (N) N0 | Esophageal Cancer TNM Staging Distal Metastasis (M) M0

China
Ohio State University

Withdrawn

Medication Therapy Management (MTM) for a Medicaid Managed Care Population Within Patient-Centered Medical Homes

Medication Therapy Management | Medication Management | Estimated Cost Avoidance | MTM
USANA Health Sciences
Elegant And Olive Health Clinic, Canada

Completed

A Follow-up Trial of Proglucamune® in the Treatment of Protective Qi Deficiency, a TCM Condition

Protective Qi Insufficiency (a Condition Term From TCM)

Canada
Novartis Pharmaceuticals

Available

Lamprene Multiple Patient Program

Non-Tuberculous Mycobacterial (NTM) Infections

United States, Canada
National Taiwan University Hospital

Unknown

Establishing a Diagnostic Test for Non-tuberculous Mycobacteria Lung Infection Using Non-tuberculous Mycobacteria Antigen Stimulation Test: From Immune Base, Standardized Setup to Validation

To Set up NTM Stimulation Test Foar Diagnosing NTM Pulmonary Infectionon.

Taiwan
Alnylam Pharmaceuticals

Completed

Phase 2 Study to Evaluate ALN-TTRSC (Revusiran) in Patients With Transthyretin (TTR) Cardiac Amyloidosis

TTR-mediated Amyloidosis

United States, United Kingdom
Pfizer

Completed

Safety And Pharmacokinetic Assessment Of Orally Administered Tafamidis In Healthy Volunteers

TTR Cardiomyopathy

Singapore
University of California, San Francisco
GlaxoSmithKline

Recruiting

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Metastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation

United States
Mayo Clinic

Completed

Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event Monitors

TTR Cardiac Amyloidosis

United States
Alnylam Pharmaceuticals

Completed

Safety and Tolerability of Patisiran (ALN-TTR02) in Transthyretin (TTR) Amyloidosis

TTR-mediated Amyloidosis

Portugal, Spain, Sweden, Brazil, United States, France, Germany
IRCCS Policlinico S. Matteo

Completed

A Study of Doxycycline and Tauroursodeoxycholic Acid (Doxy/TUDCA) Plus Standard Supportive Therapy Versus Standard Supportive Therapy Alone in Cardiac Amyloidosis Caused by Transthyretin

TTR Cardiac Amyloidosis

Italy
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Pfizer

Completed

A Study To Determine Any Effect Of Tafamidis On Electrocardiographic Intervals, Specifically The Rate Corrected QT Interval (QTc)

TTR Cardiomyopathy

United States, Singapore, Belgium
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
Rigshospitalet, Denmark

Completed

Moderate Intensity Training in Patients With Truncating Genetic Variants in TTN.

Cardiomyopathies | TTN | Truncation Mutation

Denmark
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of LFG316 in Transplant Associated Microangiopathy (TAM) Patients

Transplant Associated Microangiopathy TAM

France, United States, Germany
Pamela Munster
National Cancer Institute (NCI)

Not yet recruiting

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene Mutation

United States
Alnylam Pharmaceuticals

Completed

The Study of ALN-TTR02 (Patisiran) for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran)

TTR-mediated Amyloidosis

Portugal, Sweden, Brazil, United States, France, Spain, Germany
University of Rome Tor Vergata
University Of Perugia; University of L'Aquila

Completed

Intravesical Adjuvant Electromotive Mitomycin-C (EMDA/MMC)

Bladder Cancer TNM Staging Primary Tumor (T) Ta | Bladder Cancer TNM Staging Primary Tumor (T) T1 | Bladder Cancer Transitional Cell Grade

Italy
Alnylam Pharmaceuticals

Completed

A Extension Study to Evaluate Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Cardiac Amyloidosis

TTR-mediated Amyloidosis

United States, Canada, United Kingdom
KK Women's and Children's Hospital

Recruiting

The Therapeutic Effects of Bu Shen Yi Jing Pill on Semen Quality in Sub Fertile Males: a Randomized Controlled Trial

Infertility | Male Infertility | Reproductive Issues | Traditional Chinese Medication (TCM)

Singapore
Pfizer

Completed

Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy

ATTR-CM | TTR-CM

United States
Xiyuan Hospital of China Academy of Chinese Medical...

Unknown

Analysis of Gastrointestinal Symptoms of Outpatients With Functional Gastrointestinal Diseases（FGIDs） in Grade-A Tertiary Hospitals in China

To Analyze TCM Syndrome and Symptoms of FGIDs Patients

China
Pfizer

Completed

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy (ATTR-ACT)

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Spain, Czechia, Canada, Belgium, Netherlands, Germany, Japan, France, United Kingdom, Brazil, Italy, Sweden
Pfizer

Completed

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Taiwan, Canada, Belgium, Australia, Czechia, Sweden, Spain, Italy, Hong Kong, Germany, Netherlands, United Kingdom, France, Japan, Argentina, Brazil
Samsung Medical Center
National Cancer Center, Korea; Asan Medical Center; Seoul National University... and other collaborators

Recruiting

Clinical Study Evaluating the Proper Surgical Safety Margin for Early Stage Oral Tongue Cancers

Surgery | Tongue Cancer | Squamous Cell Carcinoma | Resection Margin | Tongue Cancer TNM Staging Primary Tumor (T) T1 | Tongue Cancer TNM Staging Primary Tumor (T) T2

Korea, Republic of
Hong Kong Baptist University
The Hong Kong Jockey Club Charities Trust

Completed

Cross-cultural Adaptation, Evaluation and Validation of Wang Qi's Constitution of TCM Questionnaire (For Old Person)

Cross-cultural Adaptation, Evaluation and Validation Study of Wang Qi's Constitution in TCM Questionnaire (For Old Person)

China
COPD Foundation

Recruiting

Bronchiectasis and NTM Research Registry

Non-CF Bronchiectasis | Nontuberculosis Mycobacteria (NTM)

United States
Insmed Incorporated

Completed

Open-label Safety Extension Study Assessing Safety and Tolerability of LAI in Patients Who Participated in Study INS-212

NTM Lung Infection Due to MAC
Kaplan Medical Center

Unknown

Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease

Cardiac TTR Amyloidosis
Pfizer

Recruiting

Vyndaqel Capsules Special Investigation (ATTR-CM)

Transthyretin (TTR) Amyloid Cardiomyopathy

Japan
Cancer Trials Ireland

Terminated

CharactHer. ICORG 12-09, V3

HER2-positive Breast Cancer | TNM Stage II-IV Breast Cancer

Ireland, Italy
Pfizer

Completed

Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And Caregivers

Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) | Transthyretin Cardiomyopathy (TTR-CM) | Familial Amyloid Cardiomyopathy | Senile Systemic Amyloidosis (SSA)
Massachusetts Eye and Ear Infirmary
London School of Hygiene and Tropical Medicine; University of Pennsylvania; The... and other collaborators

Active, not recruiting

FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial (FLAME)

Eye Diseases | Eyelid Diseases | Trichiasis | Trachomatous Trichiasis (TT) | Trachomatous

Ethiopia
Johns Hopkins University
National Cancer Institute (NCI)

Recruiting

Pancreatic Cancer Registry: For Any Person With a Personal or Family History (NFPTR)

Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

United States
State Scientific Centre of Coloproctology, Russian...

Completed

Quality of Life After Transanal Endoscopic Microsurgery (TEM) (QoLTEM)

Transanal Endoscopic Microsurgery (TEM)

Russian Federation
The Second Hospital of Shandong University
Shandong Cancer Hospital and Institute; Wuhan YZY Medical Science and Technology...

Unknown

Detection of Circulating Tumor Tells as The Guidance of the Neoadjuvant Chemotherapy of Esophageal Cancer

Esophageal Cancer TNM Staging Primary Tumor (T) T3

China
Henan Cancer Hospital

Recruiting

The Application of 3T MRI in Esophageal Cancer

Magnetic Resonance Imaging | Prognosis | Esophageal Cancer TNM Staging

China
Tianjin Medical University Cancer Institute and...

Unknown

A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast Cancer

TTP

China
Beijing University of Chinese Medicine
Harvard Medical School (HMS and HSDM); China Academy of Chinese Medical Sciences and other collaborators

Unknown

Syndrome Patterns for Chronic Atrophic Gastritis Malignant Transformation

TCM Syndrome of Chronic Atrophic Gastritis

China
Assiut University

Completed

Measuring Serum Level of Total L Carnitine in HIE and TTN (HIELcarnitine)

Compare Between the Serum Level of Lcarnitine in HIE Cases and TTN
Santo Spirito Hospital, Italy

Unknown

Surgery for Locally Advanced Colon Cancer: is it Worth it? A Multicenter Retrospective Analysis. (LACC)

Malignant Neoplasm of Large Intestine TNM Staging Primary Tumor (T) T4
Qianfoshan Hospital

Not yet recruiting

Correlation Between TCM Syndrome Factors and TSH Changes of Thyroid Hormone Withdrawal Before Iodine Therapy in Postoperative Patients With Thyroid Cancer

Differentiated Thyroid Carcinoma | TCM Syndrome Type
BioMérieux

Completed

Performance Evaluation of the VIDAS TB-IGRA Assay.

Active Tuberculosis | Latent Tuberculosis Infection | Non-Tuberculous Mycobacterial (NTM) Pneumonia

United States, France, United Kingdom, India, Brazil, Georgia, Italy, Mexico, South Africa
Bloodworks
University of Washington

Completed

A Pilot Study of N-acetylcysteine in Thrombotic Thrombocytopenia Purpura (NACinTTP)

Purpura, Thrombotic Thrombocytopenic | TTP

United States

Clinical Trials on TTM

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Drug Interventions

CROs by country

CROs in Montenegro

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Rare Diseases

Drug Interventions

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