Clinical Trials on Targeted Alpha Therapy

Total 2888 results

Rambam Health Care Campus

Unknown

Impact of Hemo-dialysis Therapy on Blood Levels of Treprostenil in End Stage Renal Disease Patients With Pulmonary Hypertension

Pulmonary Hypertension | End-Stage Renal Disease | Hemo-dialysis Therapy
MEDEX

Unknown

Zidovudine / Lamivudine + Nevirapine Twice Daily, Versus Tenofovir + Lamivudine + Nevirapine Once Daily in ARV-Naive Patients

Hiv Infection With Antiretroviral Therapy Indication | CD4 Below 350/µL or Below 15%

France
Fidia Farmaceutici s.p.a.

Recruiting

Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patients With Glaucomar or Ocular Hypertension and Concomitant Dry Eye Syndrome on Multiple Long-term Topical Hypotensive Therapy

Dry Eye Syndrome | Glaucoma and Concomitant Dry Eye Syndrome | Ocular Hypertension and Concomitant Dry Eye Syndrome | Multiple Long-term Topical Hypotensive Therapy

Italy
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA

Colorectal Cancer | Liver Metastases | Circulating Tumor Cell | Cancer, Therapy-Related

China
Sohag University

Recruiting

Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds

Diabetic Foot | Negative-Pressure Wound Therapy

Egypt
University of Southern Denmark

Recruiting

REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study) (RELIEPH)

Intensive Care Unit | Out-Of-Hospital Cardiac Arrest | Mechanical Ventilation | Resuscitation | Oxygen Therapy | Hypertension, Pulmonary Arterial

Denmark
University of Liege
Centre Hospitalier Universitaire de Nīmes; Centre Hospitalier Universitaire... and other collaborators

Recruiting

Development and Validation of the SWADOC Tool

Dysphagia | Swallowing Disorders | Disorders of Consciousness | Speech Therapy | Assessment Tool

France, Belgium
Ottawa Hospital Research Institute
The Physicians' Services Incorporated Foundation; The Kidney Foundation of... and other collaborators

Recruiting

Albumin To Enhance Recovery After Acute Kidney Injury (ALTER-AKI)

Critical Illness | Acute Kidney Injury | Hypotension | Renal Replacement Therapy

Canada
Children's Hospital of Chongqing Medical University

Recruiting

Gene Therapy for X Linked Severe Combined Immunodeficiency

Gene Therapy

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Venetoclax and Azacitidine for the Treatment of High-Risk Recurrent or Refractory Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Recurrent Myelodysplastic Syndrome | Refractory Myelodysplastic Syndrome | Therapy-Related Myelodysplastic Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission

Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Hematologic and Lymphocytic Disorder | Acute Myeloid Leukemia in Remission | FLT3 Gene Mutation | Minimal Residual Disease Persistence

United States
Lungpacer Medical Inc.

Completed

Phrenic Nerve Stimulation-Induced Lung ReAeration Trial (PIRAT)

Acute Respiratory Distress Syndrome | Ventilation Therapy; Complications

France
Clinica Universidad de Navarra, Universidad de...
DNAtrix, Inc.; Alcyone Lifesciences, Inc.

Completed

Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas

Neoadjuvant Therapy | Brainstem Glioma

Spain
University of Bergen
Haukeland University Hospital; Helse Vest; Muhimbili University of Health and...

Completed

Impact of Cotrimoxazole Use in Immunocompetent HIV Patients on Carriage of Antimicrobial Resistant Bacteria (CoTrimResist)

Opportunistic Infections | HIV-1-infection | Antibiotic Side Effect | Pneumocystis Pneumonia | Preventive Therapy

Tanzania
Institut Curie
National Cancer Institute, France; Fondation ARC

Terminated

PF-05212384 (PKI-587) for t-AML/MDS or de Novo Relapsed or Refractory Acute Myeloid Leukemia (AML) (LAM-PIK)

Acute Myeloid Leukemia, in Relapse | Therapy-related Acute Myeloid Leukemia and Myelodysplastic Syndrome | de Novo Acute Myeloid Leukemia at Diagnostic

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Completed

Effect of Bevacizumab on Radiation-induced Brain Necrosis in Patients With Nasopharyngeal Carcinoma (BRAIN)

Nasopharyngeal Carcinoma | Adverse Effect of Radiation Therapy | Brain Necrosis

China
University Hospital, Grenoble

Unknown

CPAP Effect on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypertension (POP-ART)

Obstructive Sleep Apnea | Hypertension, Resistant to Conventional Therapy

France
National Taiwan University Hospital
National Health Research Institutes, Taiwan

Unknown

Effects of Activity and Education Program on Patients With Chronic Hepatitis C Infection

Hepatitis C Virus Infection, Response to Therapy of

Taiwan
Chinese PLA General Hospital

Unknown

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

Neoplasms, Lung | Carcinoma, Non-Small Cell Lung | Drug Therapy | Genes, EGFR

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Benefits of Using a Transparent Visor to Replace the Face Mask in Speech Therapy Rehabilitation of Oral-Linguo-Facial Praxies in the Context of COVID-19: a Series of Cases (Co-VIS)

Covid19 | Oral-Linguo-Facial Praxies

France
National Cancer Institute (NCI)

Recruiting

BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy

United States
Indiana University
Indiana University Health

Recruiting

Physical Therapy for Men Undergoing Prostatectomy

Urinary Incontinence | Prostate Cancer | Pelvic Floor Physical Therapy

United States
University College, London

Recruiting

Focal Therapy for Prostate Cancer Using HIFU (INDEX)

Urinary Incontinence | Prostate Cancer | Male Erectile Disorder | Therapy-related Toxicity

United Kingdom
Shanghai Jiao Tong University School of Medicine

Completed

Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

Oral Cancer | VEGFR2 Inhibitor | Programmed Cell Death 1 Inhibitor | Inductive Therapy

China
Federal Center of Cerebrovascular Pathology and...

Unknown

Russian Prospective Multicenter Registry Study of Intravenous Thrombolytic Therapy for Acute Ischemic Stroke (IVT-AIS-R)

The Aim the Study is to Collect and Analyze Data on Patients With Acute Ischemic Stroke During Intravenous Thrombolytic Therapy With Alteplase

Russian Federation
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Pain | Head and Neck Cancer | Mucositis | Oral Complications of Radiation Therapy

United States
Rambam Health Care Campus

Completed

Cardiopulmonary Exercise Test to Quantify Enzyme Replacement Response in Pediatric Pompe Disease

Enzyme Replacement Therapy in Pompe Disease
Mespere Lifesciences Inc.

Unknown

Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter

Sepsis | Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy | Cardiogenic Shock Post Myocardial Infarction | Hypoxemic Respiratory Failure.

Canada
Assaf-Harofeh Medical Center

Unknown

Hyperbaric Oxygen Therapy and Angiogenesis in Diabetic Patients With Foot Ulcers

Diabetic Foot Ulcers | Angiogenesis | Hyperbaric Therapy

Israel
University of Pittsburgh

Recruiting

Longitudinal Study of Neurodegenerative Disorders

Lysosomal Storage Diseases | Leukodystrophy | Niemann-Pick Diseases | Batten Disease | Gaucher Disease | Krabbe Disease | Alpha-Mannosidosis | Osteopetrosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | GM1 Gangliosidoses | MPS I | MPS II | Vanishing White Matter Disease | Multiple Sulfatase Deficiency... and other conditions

United States
BeiGene

Not yet recruiting

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor | Advanced Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | Alpha-fetoprotein (AFP)-Producing Gastric Cancer | Extragonadal Yolk Sac Tumors | Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer
London North West Healthcare NHS Trust

Recruiting

Perioperative Testosterone Replacement Therapy in Sarcopenic Male Colorectal Cancer Patients (TERESA)

Colorectal Cancer | Sarcopenia | Perioperative Care | Hypogonadism, Male | Testosterone Replacement Therapy

United Kingdom
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Toripalimab Injection in the Treatment of Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy and Are Positive Specific Markers

Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy

China
National Cancer Institute (NCI)

Active, not recruiting

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy

United States
Capital Medical University
Zhejiang University School of Medicine, Obstetrics and Gynecology Hospital; Nutricia Pharmaceutical Co., Ltd...

Completed

Medical Nutrition Therapy Combined With TPF-DM in Pregnant Women With Gestational Diabetes Mellitus

Gestational Diabetes Mellitus | Gestational Weight Gain | Adverse Pregnancy Outcomes | Fasting Plasma Glucose | Medical Nutrition Therapy | HbA1c

China
Dubai Fertility Center

Withdrawn

Letrozole Versus Hormonal Preparation in Frozen Cycles of PCOS Patients.

Miscarriage | Frozen Embryo Transfer | Hormone Replacement Therapy | Letrozole | Live Birth | Polycystic Ovarian Disease
Shanghai Jiao Tong University School of Medicine

Completed

Neoadjuvant Toripalimab and Paclitaxel/Cisplatin on Pathological Response in Oral Squamous Cell Carcinoma Patients

Oral Cancer | Induction Chemotherapy | Programmed Cell Death 1 Inhibitor | Inductive Therapy

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Nivolumab in AML in Remission at High Risk for Relapse

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia in Remission | Blasts Under 10 Percent of Bone Marrow Nucleated Cells | Therapy-Related Myeloid Neoplasm

United States
MedCu Technologies Ltd.

Completed

Comparison of Wound Healing Between MedCu Dressings With Copper Oxide and Negative Pressure Wound Therapy Treatment

Wounds and Injuries | Diabetic Foot Ulcer | Negative Pressure Therapy

Israel
Hospital Civil de Guadalajara

Completed

Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1

Acute Kidney Injury | Fluid Overload | Decompensated Heart Failure | Ultrasound Therapy; Complications | Cardiorenal Syndrome

Mexico
Cairo University

Completed

Feasibility Of Oral Sensorimotor Stimulation On Oropharyngeal Dysphagia In Children With Spastic Cerebral Palsy

Physical Therapy

Egypt
The George Institute
National Health and Medical Research Council, Australia; Baxter Healthcare...

Completed

A Clinical Trial of IntensiVE Dialysis (ACTIVE)

End Stage Renal Disease | Renal Replacement Therapy | End Stage Kidney Disease | Renal Dialysis | Uremia

New Zealand, Canada, Australia, China
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Terminated

Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Stenosis (ANDORRA) (ANDORRA)

Hypertension | Hypertension Resistant to Conventional Therapy | Angiographically Proven Grade III Unilateral or Bilateral Atherosclerotic Renal Artery Stenosis (ARAS) Greater Than or Equal to 60 Percent

France
Impulse Dynamics

Recruiting

Assessment of Combined CCM and ICD Device in HFrEF (INTEGRA-D)

Heart Failure | Arrhythmias, Cardiac | Ventricular Fibrillation | Ventricular Tachycardia | Implantable Defibrillator User | Heart Failure With Reduced Ejection Fraction | Ischemic Cardiomyopathy | Sudden Cardiac Arrest | Non-ischemic Cardiomyopathy | CCM Therapy

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm | Acute Myeloid Leukemia Post Cytotoxic Therapy
Hospices Civils de Lyon

Recruiting

Is Myocardial Stunning Induced by Continuous Renal Replacement Therapy a Reality in Critically Ill Patients? (MS-CRRT)

Myocardial Stunning | Acute Kidney Injury KDIGO 3 | Continuous Renal Replacement Therapy Initiated by the Clinician in Charge Without Emergency

France
Alberta Health Services, Calgary
Alberta Cancer Foundation; University of Victoria

Recruiting

Early Integration of Palliative and Supportive Care in Cellular Therapy (PALS_CT)

Lymphoma | Leukemia | Multiple Myeloma | Blood Cancer | Stem Cell Transplant Complications | Chimeric Antigen Receptor T-cell Therapy

Canada
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia

Oral Complications of Radiation Therapy | Stage I Laryngeal Cancer | Stage II Laryngeal Cancer

United States
Sinai University
Al-Azhar University; Misr International University; Delta University for Science...

Completed

Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion

Bone Density Increased | T2DM (Type 2 Diabetes Mellitus) | Low-level Laser Therapy

Egypt
University of Maryland, Baltimore
Merck Sharp & Dohme LLC; Cairo University

Withdrawn

Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4 (CLEAR-C4)

Hepatitis C Virus Infection, Response to Therapy of

Egypt

Clinical Trials on Targeted Alpha Therapy

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