Clinical Trials on Terminal Illness in South Africa

Total 53 results

University of Athens

Completed

End-of-life Practices in 2019 vs. 2014

Heart Arrest | Terminal Illness | Ethics, Narrative

Greece, Belgium
Milton S. Hershey Medical Center
University of Kentucky; Hospice Foundation of America

Recruiting

Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations

Communication | Terminal Illness | Chronic Illness | Advance Care Planning | Advance Directives

United States
Chris Hani Baragwanath Academic Hospital
Masimo Corporation

Completed

Usefulness of Non-invasive Pulse Co-oximetry Haemaglobin Measurements in Critically Ill Black Patients

Critically Ill Black Patients

South Africa
University of Stellenbosch
Fresenius Kabi

Recruiting

Effect of Combined IV Bolus Amino Acid Supplementation and Mobilisation on Muscle Mass in Patients Over the First Week of ICU Care: RCT

Critical Illness

South Africa
University of Cape Town
University of Pennsylvania; Medical Research Council, South Africa; Carnegie... and other collaborators

Completed

Study Comparing the Effectiveness of Incentives on Physical Activity Behavior in a Health Insured Population (PAIS)

Wellness Programs | Physical Activity Behavior

South Africa
City University of Hong Kong
Stanford University; Harvard University

Completed

International REACH Forgiveness Intervention

Mental Health Wellness

Colombia, Indonesia, South Africa, Ukraine
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
Australian and New Zealand Intensive Care Research...
Baxter Healthcare Corporation

Completed

Intensive Nutrition in Critically Ill Adults (INTENT)

Critical Illness | Critically Ill

Australia, New Zealand
South West Sydney Local Health District

Completed

Fluid Responsiveness After CArdiac Surgery Study (FRACAS)

Critically Ill | Hypovolemia

Australia
Takeda
Theravance Biopharma

Completed

A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance

Enteral Feeding Intolerance

Australia
Applied Physiology Pty Ltd
Trident Clinical Research Pty Ltd

Completed

Registration Enabling Study of the Safety and Efficacy of the Use of the Navigator Circulatory Management System (NAV-1)

Critical Illness | Intensive Care

Australia
Rakshit Panwar

Recruiting

Individualised Blood Pressure Targets Versus Standard Care Among Critically Ill Patients With Shock (REACT-SHOCK)

Shock | Critical Illness

Australia
VA Office of Research and Development
US Department of Veterans Affairs

Completed

Evaluation of Peer Specialists on VA PACTs (Peers on PACT)

Mental Illness | Physical Illness

United States
Baxter Healthcare Corporation

Enrolling by invitation

Timmy3 Module Clinical Accuracy ISO 80601-2-56:2017 + A1 2018

Febrile Illness

United States
The George Institute
National Health and Medical Research Council, Australia; University of British... and other collaborators

Completed

Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)

Hyperglycemia | Critical Illness

Australia
Hasanuddin University

Completed

High Protein Formula on Enteral Feeding in Clinical Improvement and Malnutrition at Intensive Care Unit Patients

Critically Ill | Intensive Care Unit

Indonesia
University of Sheffield
University of Derby

Completed

Feasibility Study of an App-based Intervention to Improve Wellbeing (IWUN)

Mental Health Wellness 1

United Kingdom
Australian and New Zealand Intensive Care Research...

Completed

INTENT-Muscle (A Sub-study of INTENT)

Critically Ill

Australia, New Zealand
Erasmus Medical Center

Completed

Music for Anxiety in Critically Ill Patients (RELACS)

Anxiety

Netherlands
Australian and New Zealand Intensive Care Research...

Completed

The Augmented Versus Routine Approach to Giving Energy Trial (TARGET)

Critical Illness

Australia, New Zealand
Daren K. Heyland
Ministry of Research, Innovation and Science, Ontario; Canadian Foundation...

Completed

PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study (PERFECTIS)

Critically Ill | Intensive Care Unit

Canada, United States
GlaxoSmithKline

Completed

Evaluation of Single Doses of GSK962040 in Critically Ill Patients With Enteral Feed Intolerance

Gastroparesis

Australia
The George Institute

Completed

Fludrocortisone Dose Response Relationship in Septic Shock - FluDReSS (FluDReSS)

Septic Shock | Critically Ill

Australia
Australian and New Zealand Intensive Care Research...

Recruiting

Indirect Calorimetry Guided Energy Provision in Critically Ill Patients With Obesity (DIRECT)

Obesity | Critical Illness

Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia

Completed

Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients (SPICE III RCT)

Critical Illness and Mechanical Ventilation

Australia, United Kingdom, Italy, New Zealand, Malaysia, Ireland, Switzerland, Saudi Arabia
MedImmune LLC

Completed

A Study to Evaluate the Immunogenicity of Quadrivalent Live Attenuated Influenza Vaccine (LAIV) in Children (LAIV)

Healthy or Stable Chronic Illness

United States
Pfizer

Recruiting

Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults. (RENOIR)

Lower Respiratory Tract Illness

United States, Argentina, Canada, Finland, Japan, Netherlands, South Africa
Australian and New Zealand Intensive Care Research...
Monash University; The Alfred; St Vincent's Hospital, Sydney; Royal Prince Alfred... and other collaborators

Completed

Extracorporeal Membrane Oxygenation Physical Training (ECMO-PT)

Extracorporeal Membrane Oxygenation Complication | Critically Ill, Mechanically Ventilated

Canada, Australia
Australian and New Zealand Intensive Care Research...

Recruiting

Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults (BoneZone)

Critical Illness | Osteoporosis

Australia, New Zealand
Millennium Pharmaceuticals, Inc.

Terminated

TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)

Critical Illness | Enteral Nutrition | Enteral Feeding Intolerance

United States, Canada, Australia, United Kingdom
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Intensive Care National... and other collaborators

Completed

Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation (TEAM(III))

Critically Ill, Mechanically Ventilated

Australia, New Zealand, United Kingdom, Ireland, Germany
The University of New South Wales
Australian Government Department of Health and Ageing

Completed

Multicomponent Risk Factor Intervention for People With a Severe Mental Illness: a Feasibility Study

Behavior, Addictive | Obesity | Psychotic Disorder

Australia
University of Ulster

Completed

Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People With SMI (WORtH)

Schizophrenia | Bipolar Disorder | Major Depression | Mental Illness | Psychosis

Ireland, United Kingdom
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Medical Research Institute... and other collaborators

Enrolling by invitation

The TEAM Long-Term Cohort Study (A Sub-study of TEAM(III))

Critically Ill | Mechanical Ventilation | Long Term Outcome

Australia
GlaxoSmithKline

Terminated

Nutritional Adequacy Therapeutic Enhancement in the Critically Ill. The NUTRIATE Study

Gastroparesis

Canada, Australia, United States
VA Office of Research and Development

Completed

PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness) (PTSD/SMI)

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Major Depression | Post Traumatic Stress Disorder

United States
Duke University
Johns Hopkins University; National Institutes of Health (NIH); Vanderbilt University... and other collaborators

Terminated

DOSE Trial of Opioid Sparing Effect (DOSE)

Critically Ill | Dexmedetomidine | Mechanical Ventilation Complication

United States
The George Institute
Sunnybrook Health Sciences Centre; Imperial College London

Completed

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients (SuDDICU)

Sepsis | Critical Illness | Septic Shock | Ventilator Associated Pneumonia

Australia, Canada, United Kingdom
Emergo Therapeutics, Inc.

Completed

Efficacy and Safety of Norketotifen in Uncomplicated Influenza-like Illness

Influenza | Influenza -Like Illness

United States
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; The Alfred; National... and other collaborators

Recruiting

The EXCEL Registry of Patients Requiring ECMO

Cardiac Arrest | Critically Ill | Acute Respiratory Failure | Acute Heart Failure

Australia, New Zealand
Australian and New Zealand Intensive Care Research...
The Alfred

Completed

Recovery of Patients From COVID-19 After Critical Illness

COVID-19 | Critical Illness

Australia
Kythera Biopharmaceuticals

Completed

Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area

Moderate or Severe Submental Fullness

United States, Canada
McMaster University
Canadian Institutes of Health Research (CIHR); Australian and New Zealand Intensive... and other collaborators

Completed

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)

Critical Illness | Deep Venous Thrombosis

United States, Australia, Canada, Saudi Arabia, Brazil, United Kingdom
Emergo Therapeutics, Inc.

Completed

Norketotifen for the Treatment of Uncomplicated Influenza-like Illness

Influenza -Like Illness

United States
Murdoch Childrens Research Institute
Bill and Melinda Gates Foundation; Royal Children's Hospital

Completed

BCG Vaccination to Protect Healthcare Workers Against COVID-19 (BRACE)

COVID-19 | Corona Virus Infection | Coronavirus Disease 2019 (COVID-19) | Respiratory Illness

Australia, Brazil, Netherlands, Spain, United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

Study to Assess the Effectiveness of RCHOP With or Without VELCADE in Previously Untreated Non-Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma Patients

Non-Germinal B-Cell-like (GCB) Diffuse Large B-cell Lymphoma (DLBCL)

United States
Sunnybrook Health Sciences Centre

Completed

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE)

Sepsis | Mortality | Bacteremia | Critically Ill | Intensive Care | Antimicrobial

New Zealand, United States, Canada, Australia, Switzerland, Saudi Arabia, Israel
Critical Care Pharmacotherapy Trials Network
University of Arkansas

Completed

Drug Resistance Factors In Healthcare-associated Pneumonia (DEFINE)

Pneumonia | Critical Illness

United States, Saudi Arabia
Erasmus Medical Center
Leiden University Medical Center; Medical Center Haaglanden; Rijnstate Hospital; Maasstadziekenhu... and other collaborators

Recruiting

HIV Indicator Diseases in Hospital and Primary Care (#AwareHIV)

HIV Infections | Acquired Immunodeficiency Syndrome | Sexually Transmitted Diseases, Viral | Pneumonia | Psoriasis | Weight Loss | Thrombocytopenia | Leukopenia | Dermatitis, Seborrheic | Herpes Zoster | Lymphadenopathy | Uterine Cervical Dysplasia | Primary Health Care | Diarrhea Chronic | Candida Infection | Infectious... and other conditions

Netherlands
University of California, Santa Barbara
Rendever, Inc.

Completed

Technology and Family Thriving Study (Thrive)

Quality of Life | Dementia | Alzheimer Disease | Mental Health Wellness 1 | Loneliness | Caregiver Burnout | Family Relationship

United States

Clinical Trials on Terminal Illness in South Africa

Sponsors and Collaborators

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CROs in Mauritius

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