Clinical Trials on Thrombophilia Due to Acquired Antithrombin III Deficiency

Total 99 results

Mayo Clinic
rEVO Biologics

Terminated

Response of Recombinant Antithrombin in Heparin Resistant Patients Undergoing Cardiac Surgery

Thrombophilia Due to Acquired Antithrombin III Deficiency

United States
Octapharma

Not yet recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Acquired Antithrombin Deficiency
Instituto Grifols, S.A.

Completed

Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass

Coronary Artery Bypass | Acquired Antithrombin III Deficiency

Italy
Octapharma

Recruiting

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery

Congenital Antithrombin Deficiency

Spain, United States, Italy, France, Hungary, Austria, Germany, United Kingdom
Kyowa Hakko Kirin UK, Ltd.

Completed

A Study of KW-3357 in Congenital Antithrombin Deficiency

Congenital Antithrombin Deficiency

France, Germany, Italy, Sweden, United Kingdom
Mayo Clinic
rEVO Biologics

Withdrawn

Response of Continuous Recombinant Antithrombin Infusion in Postcardiotomy ECMO Patients

Antithrombin Deficiency Type 2
rEVO Biologics

Completed

Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations. (rhAT)

Antithrombin Deficiency, Congenital

France, United Kingdom, Germany, United States, Sweden, Italy
Rennes University Hospital

Completed

Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation (ATECMO)

Severe Cardiac Insufficiency

France
Duke University
Grifols Biologicals, LLC

Completed

Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery

ATIII Deficiency

United States
Universitair Ziekenhuis Brussel

Not yet recruiting

Belgian Antithrombin Deficiency Registry

Antithrombin III Deficiency

Belgium
rEVO Biologics

Completed

Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery

Antithrombin III Deficiency

United States, France, United Kingdom, Germany, Canada, Austria, Australia, Italy
Grifols Biologicals, LLC

Active, not recruiting

Safety, Pharmacokinetics and Efficacy of an ATIII Concentrate

Antithrombin III Deficiency
Dr. Siyami Ersek Thoracic and Cardiovascular Surgery...

Completed

Prospective Investigation of Antithrombin III Deficiency in Adult Patients With ECMO

Extracorporeal Membrane Oxygenation Complication | Antithrombin III Deficiency

Turkey
Beth Israel Deaconess Medical Center
Amgen

Completed

Pharmacokinetics of Leptin Administration During Fasting

Energy Deficiency Due to Short-term Fasting

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Role of Xanthophylls in Visual Function (Xanthovision)

Nutrition Deficiency (Xanth Deficiency) Due to A Particular Kind of Food
Ain Shams University

Recruiting

Carnitine Supplementation in Pediatric Hemodialysis Patients

Carnitine Deficiency Due to Hemodialysis

Egypt
Vastra Gotaland Region
Octapharma

Withdrawn

Atenativ Effect on Uterine Blood Flow and Preeclampsia

Antithrombin III Deficiency

Sweden
Hospital for Special Surgery, New York
Montefiore Medical Center

Completed

Effect of HCQ on AnxA5 Resistance Assay in Antiphospholipid (aPL) Positive Patients With and Without Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus | Antiphospholipid Syndrome | Thrombophilia Due to Antiphospholipid Antibody

United States
IRCCS Fondazione Stella Maris

Recruiting

Optical Imaging as a Tool for Monitoring Brain Function in Creatine Deficiency Syndromes

Creatine Deficiency, X-linked | Creatine Deficiency Syndrome Due to Gamt Deficiency

Italy
Genelex Corporation
University of Utah

Completed

YouScript IMPACT Registry (IMPACT)

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme Deficiency | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome... and other conditions

United States
The University of The West Indies
International Atomic Energy Agency

Completed

Quality of Protein From the Common Bean

Nutrition Deficiency Due to A Particular Kind of Food

Jamaica
Holostem Terapie Avanzate s.r.l.
Cromsource

Completed

Follow-up Study After ACLSCT for Restoration of Corneal Epithelium in Patients With LSCD Due to Ocular Burns (HOLOCORE-FU)

Limbal Stem Cell Deficiency Due to Ocular Burn

Italy
Genelex Corporation
Harding University

Completed

Pharmacogenetic Testing Among Home Health Patients

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme... and other conditions

United States
Al-Azhar University

Completed

Three Levels of Force Application for Maxillary Protraction (MaxiProtr)

Skeletal Class 3 Malocclusion Due to Maxillary Deficiency

Egypt
Genelex Corporation

Completed

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome P450 CYP2C9 Enzyme Deficiency | Cytochrome P450 CYP2C19 Enzyme Deficiency | Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant | CYP2D6 Polymorphism | Ultrarapid... and other conditions

United States
Achaogen, Inc.
Department of Health and Human Services

Completed

A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) (CARE)

Bloodstream Infections (BSI) Due to CRE | Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE | Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE | Complicated Urinary Tract Infection (cUTI) Due to CRE | Acute Pyelonephritis (AP) Due to CRE
Iowa State University

Completed

Effect of Iron Supplements on the Growth of Enteric Pathogens

Iron-deficiency | Iron Deficiency Anemia | Iron Deficiency Anemia Treatment | Iron Deficiency Anaemia Due to Dietary Causes

United States
Enrique Ginzburg
Grifols Biologicals, LLC

Terminated

Antithrombin III in Infectious Disease Caused by COVID-19

Covid19 | Antithrombin III Deficiency

United States
Hospital Universitari Vall d'Hebron Research Institute
Universidad de Murcia

Unknown

"Incidence and Consequences of Disorders of Glycosylation in Patients With Conotruncal and Septal Heart Defects" ((CARDIoG))

Congenital Heart Diseases | Antithrombin III Deficiency | Congenital Disorder of Glycosylation | Conotruncal Defects

Spain
Central Hospital, Nancy, France

Completed

Nutrition Protocol and Premature Infants' Growth (Nutriproto)

Premature Infants | Growth Retardation | Nutrition Deficiency Due to Insufficient Food
Texas Tech University Health Sciences Center, El...

Completed

IV Iron Versus Standard Treatment for Iron Deficiency Anemia in the Emergency Department

Iron-deficiency | Iron Deficiency Anemia | Iron Deficiency Anemia Treatment | Iron Deficiency Anemia Due to Blood Loss

United States
Fondazione Telethon

Completed

Evaluating the Effectiveness of STRIMVELIS Risk Minimization Measures (RMMs)

Severe Combined Immunodeficiency Due to ADA Deficiency

Italy
Fondazione Telethon

Active, not recruiting

Methodology Study of Retroviral Insertion Site Analysis in Strimvelis Gene Therapy

Severe Combined Immunodeficiency Due to ADA Deficiency

Italy
Great Ormond Street Hospital for Children NHS Foundation...
Orchard Therapeutics

Completed

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Severe Combined Immunodeficiency Due to ADA Deficiency

United Kingdom
University of California, Los Angeles

Withdrawn

A Clinical Study to Enable Process Validation of Commercial Grade OTL-101

Severe Combined Immunodeficiency Due to ADA Deficiency

United States
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Horizon...

Recruiting

Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID (RAG1-SCID)

Severe Combined Immunodeficiency Due to RAG1 Deficiency

Spain, Netherlands, Italy, Poland, Australia, Turkey, United Kingdom
University of California, Los Angeles
Orchard Therapeutics; California Institute for Regenerative Medicine (CIRM)

Completed

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Severe Combined Immunodeficiency Due to ADA Deficiency

United States
University of British Columbia
Vancouver Coastal Health Research Institute; Genome British Columbia

Recruiting

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (ACCURATE)

Acute Coronary Syndrome | Familial Hypercholesterolemia | STEMI | NSTEMI - Non-ST Segment Elevation MI | Familial Hypercholesterolemia - Heterozygous | Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B | Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation and other conditions

Canada
IVI Madrid

Withdrawn

Differences in Ovarian Reserve Markers and Vitamin D Between Infertile Indian, Arabian and Caucasian Population

Vitamin D Deficiency | Hormone Deficiency | Female Infertility Due to Diminished Ovarian Reserve | Follicular Cyst of Ovary

Spain
National Human Genome Research Institute (NHGRI)

Recruiting

Diagnosis and Treatment of Patients With Inborn Errors of Metabolism

Arterial Calcification Due to Deficiency of CD73

United States
Patricia Duque González

Completed

Impact of Acquired FXIII Deficiency on Morbidity and Mortality

Acquired Factor XIII Deficiency Disease

Spain
University of Campania "Luigi Vanvitelli"
Federico II University

Completed

Colistin and Rifampicin for MDR-Acinetobacter (CoRAb)

Pneumonia, Ventilator-Associated | Hospital Acquired Pneumonia | Infection Due to Resistant Bacteria | Infection of Bloodstream | Infectious Disease of Abdomen
NMC Specialty Hospital
Govind Ballabh Pant Institute of Postgraduate Medical Education and Research and other collaborators

Completed

How Well do we Feed the Critically Ill Patients (WE-FEED)

Critically Ill | Feeding Patterns | Parenteral Nutrition Associated Liver Disease | Enteral and Supplement Feeds Adverse Reaction | Nutrition Deficiency Due to Insufficient Food

United Arab Emirates
Rambam Health Care Campus

Recruiting

IV Sodium Ferric Gluconate Complex in Patients Undergoing TAVI

Aortic Stenosis | Iron Deficiency Anemia Due to Blood Loss

Israel
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Obesity | Genetic Obesity | Obesity Due to Melanocortin 4 Receptor Deficiency

United States, United Kingdom, Germany, Netherlands, France, Canada, Greece, Israel, Spain
West China Hospital

Unknown

Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients

Hepatic Encephalopathy | Cirrhosis | Acquired Portal-systemic Shunt Due to Cirrhosis

China
St. Justine's Hospital
Toronto-Dominion Bank of Canada Funds for Clinical Research projects.

Completed

Pilot Study of a New Device (Buzzy®) for Procedural Pain Relief During Needle-Related Procedures in Paediatric Patients

Immune Deficiency | Autoimmune Rheumatologic Disease | Pain Due to Certain Specified Procedures | Child/Adolescent Problems

Canada
Avni Joshi

Enrolling by invitation

Senolytics Treatment of Interstitial Lung Disease in Common Variable Immunodeficiency

Common Variable Immunodeficiency | Interstitial Lung Disease Due to Systemic Disease

United States
Angel Augusto Perez Calatayud
Grupo Mexicano para el Estudio de la Medicina Intensiva

Completed

Patient Blood Management for Massive Obstetric Hemorrhage

Post Partum Hemorrhage | Transfusion Related Complication | Fibrinogenolysis; Hemorrhage | Fibrinogen; Deficiency, Acquired | Massive Hemorrhage

Mexico
Johns Hopkins Bloomberg School of Public Health
Massachusetts General Hospital; Mayo Clinic; National Institute of Diabetes and... and other collaborators

Not yet recruiting

Gastroparesis Registry 4 (GpR4)

Gastroparesis | Gastro-Intestinal Disorder | Gastroparesis Due to Diabetes Mellitus Type I | Gastroparesis Nondiabetic | Gastroparesis Due to Diabetes Mellitus Type II | Functional Disorder of Gastrointestinal Tract

United States

Clinical Trials on Thrombophilia Due to Acquired Antithrombin III Deficiency

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CROs in Bulgaria

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