Clinical Trials on Transfusional Iron Overload

Total 1575 results

National Institutes of Health Clinical Center (CC)

Completed

Complement (C1q) Binding to HLA Antibodies in a Solid-phase Immunoassay and Clinical Effect on Platelet Transfusion

Thrombocytopenia | Platelet Transfusion Refractoriness

United States
Sofia Ramström

Enrolling by invitation

Transfusion of Whole Blood in Acute Bleeding (HEPEP)

Blood Transfusion | Acute Bleeding

Sweden
Catherine Cibulskis, MD
St. Louis University

Active, not recruiting

The Utility of MRI Scoring to Predict Neurodevelopmental Outcomes in Survivors of Twin-to-Twin Transfusion Syndrome

Fetofetal Transfusion

United States
Northwestern University
Emory University; Louisiana State University Health Sciences Center Shreveport

Completed

Improving Prescription Drug Warning Labels

Enhanced Text | Enhanced Text + Icon

United States
Riphah International University

Recruiting

Cross Fiber Fascial Manipulation and Stretching Techniques in Overhead Throwing Athletes

Overhead Throwing Athletes | Tennis Players, Bowlers, Volleyball Players

Pakistan
Damascus University

Recruiting

Re-infusion of Unwashed Shed Blood During Off-pump Surgery

Coronary Artery Disease | Cardiovascular Complication | Blood Transfusion Complication

Syrian Arab Republic
Copenhagen University Hospital, Hvidovre

Completed

Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy

Anastomotic Leak | Fluid Overload | Intestinal Obstruction | Pathophysiology | Intestinal Perforation

Denmark
University Hospital, Lille

Recruiting

Transhepatic Echography for Fluid Responsiveness After Cardiovascular Surgery (THEFRACS)

Fluid Overload | Fluid Responsiveness | Venous Congestion | Cardiovascular Surgery | Inferior Vena Cava Abnormality

France
Hamilton Health Sciences Corporation
McMaster University

Withdrawn

Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery (RAPPER-MAN)

Coronary Artery Disease | Fluid Overload | Hemodilution

Canada
University Hospital Schleswig-Holstein

Completed

Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored With Electrical Impedance Tomography

Respiratory Failure | Fluid Overload | Circulatory Failure | Fluid Responsiveness

Germany
Novartis Pharmaceuticals

Completed

Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet (Jupiter)

Non-transfusion-dependent Thalassemia | Transfusion-dependent Thalassemia

Egypt, Turkey, Thailand, Lebanon, Morocco, Saudi Arabia, Vietnam
Poznan University of Physical Education

Recruiting

Effect of Krill Oil Supplementation on Red Blood Cell Physiology Against Changes in Markers of Iron Metabolism.

Iron Metabolism Disorders | Oxidative Stress | Red Blood Cell Disorder

Poland
Stanger Hospital
Otto Kranendonk Fonds - Dutch Association of Tropical Health (request pending)

Completed

Effect of Delayed Cord Clamping on Haematological Status in Low Birth Weight Infants

Low Birth Weight | Perinatology | Iron Status | Cord Clamping

South Africa
Vifor Pharma
SGS S.A.

Completed

Ferric Carboxymaltose Treatment to Improve Fatigue Symptoms in Iron-deficient Non-anaemic Women of Child Bearing Age (Prefer)

Iron Deficiency

Austria
University of Colorado, Denver

Terminated

INR-Triggered Transfusion In GI Bleeders From ER (I-TRIGER)

Liver Diseases | Respiratory Distress Syndrome, Adult | Gastrointestinal Hemorrhage | Transfusion Related Lung Injury

United States
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors

Thoracic Surgery | Cardiac Disease | Blood Transfusion; Hemoglobinemia

Spain
National Institutes of Health Clinical Center (CC)

Recruiting

The SOLID Platelet Study

Thrombocytopenia | Platelet Transfusion Refractoriness (PTR)

United States
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of the 1-year Prognosis of Patients Under Veno-arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock With Blood Transfusion Requirement (HemoECMO)

Extracorporeal Membrane Oxygenation Complication | Transfusion Related Complication | Blood Cells Transfusion
CHU de Reims

Unknown

Hydratation Status at Initiation of Peritoneal Dialysis: Study of the Role of Peritoneal Permeability

Peritoneal Dialysis | Chronic Kidney Disease | Fluid Overload | Peritoneal Hyperpermeability

France
Royal College of Surgeons, Ireland
patientMpower Ltd.; Enterprise Ireland; Beaumont Hospital; Design to Value Ltd

Completed

Haemodialysis Outcomes & Patient Empowerment Study 02 (HOPE-02)

End Stage Renal Disease | Dialysis; Complications | Volume Overload

Ireland
Instituto Venezolano de Investigaciones Cientificas
Seguros Caracas Foundation; National Fund for Science and Technology, Science...

Completed

Low Dose β-carotene Supplementation Diminishes Oxidative Stress in Type 2 Diabetics and Healthy Individuals

Diabetes Mellitus | Iron Metabolism Disorders | Oxidative Stress

Venezuela
University College, London

Completed

The UK CAVIAR Study

Iron Deficiency | Anaemia | Cardiac Patients | Vascular Patients
Erasme University Hospital

Completed

Do Anesthesiologists Follow Guidelines on Perioperative Use of Tranexamic Acid? (Periop_TXA)

Blood Loss, Surgical | Blood Transfusion | Tranexamic Acid

Belgium
Assiut University

Not yet recruiting

Comparing TASH Score and Modified TBSS in Trauma Patients in Need for Massive Blood Transfusion

Massive Blood Transfusion in Trauma Patients
Karolinska University Hospital
Karolinska Institutet

Unknown

Adjusted Calculation of Heparin and Protamin Dosing and Correlation With Postoperative Bleeding and Transfusions

Bleeding | Cardiac Surgery | Heparin | Transfusion | Protamine Sulfate

Sweden
Istituto Ortopedico Galeazzi

Completed

Iron Supplementation in Hip/Knee Surgery (SID-IRON)

Anemia | Orthopedic Disorder | Knee Arthropathy | Hip Arthropathy | Iron Poor Blood

Italy
Istituto Ortopedico Galeazzi

Completed

Iron and Vitamin Supplementation in Hip/Knee Surgery

Anemia | Orthopedic Disorder | Knee Arthropathy | Hip Arthropathy | Iron Poor Blood

Italy
Centre Hospitalier Universitaire de Besancon
University Hospital, Strasbourg, France; University Hospital, Angers; Centre... and other collaborators

Completed

Old Red Blood Cell In Renal Transplantation (ORBIT)

Transfusion Reaction | Disorder Related to Renal Transplantation
Natera, Inc.

Recruiting

Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management. (ZTWINS)

Pregnancy Complications | Twin to Twin Transfusion Syndrome | Multiple Gestation; Maternal Care

United States
Pontificia Universidad Catolica de Chile

Recruiting

Fluid unLoading On Weaning (FLOW) (FLOW)

Fluid Overload | Weaning Failure | Cardiac Failure Acute

Chile
Haukeland University Hospital
Norwegian Armed Forces Medical Service

Completed

Storage Temperature and Quality of Leucoreduced Whole Blood (BFF)

Trauma | Austere Environment | Blood Bank | Buddy Transfusion

Norway
Szeged University
Medical Centre Hungarian Defence Forces

Unknown

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Hypoxia | Anemia | Blood Transfusion; Hemoglobinemia

Hungary
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; The Affiliated... and other collaborators

Recruiting

Sequential Infusion of CD19 and BCMA CAR-T Cells to Improve PTR in Patients With AL

Platelet Transfusion Refractoriness | Acute Leukemia in Remission

China
Johann Wolfgang Goethe University Hospital
Wuerzburg University Hospital

Recruiting

Liberal Transfusion Strategy in Elderly Patients (LIBERAL)

Anemia | Surgery | Transfusion-dependent Anemia

Germany
Oregon Health and Science University

Withdrawn

Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis (SHUM)

Respiratory Failure | Hypernatremia | Volume Overload

United States
Erasme University Hospital

Recruiting

Transfusion Surveillance in Anaesthesia (STAR)

Blood Loss | Anesthesia | Transfusion Reaction | Blood Coagulation Disorder | Transfusion Related Complication | Side Effect | Anesthesia; Shock | Fresh Blood Stool

Belgium
Assiut University

Unknown

Effect of Iron Deficiency Anemia on HBA1C in Patients With Diabetic Foot Ulcer Grade (1and2)

Iron Deficiency Anemia | HBA1C
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT) (ENERGIZE-T)

Transfusion-dependent Alpha-Thalassemia | Transfusion-dependent Beta-Thalassemia

Spain, Taiwan, Thailand, United States, France, Canada, Malaysia, Germany, Netherlands, Bulgaria, United Kingdom, Turkey, Italy, Greece, United Arab Emirates, Brazil, Denmark, Lebanon, Saudi Arabia
Tungs' Taichung Metroharbour Hospital

Completed

Cardiac Biomarkers and Iron Status in Hemodialysis Patients

Heart Failure | Iron-deficiency

Taiwan
University of California, San Diego
Grifols Biologicals, LLC

Completed

Fluid Mobilization in Hospitalized Patients With Acute Kidney Injury

Fluid Overload | Hypotension During Dialysis
AstraZeneca
ASK CRE Private Limited

Completed

Non-interventional Study of COPD Patients With Asthma Overlap Syndrome in Viet Nam and Taiwan

Patients With Asthma-COPD Overlap Syndrome (ACOS)

Vietnam, Taiwan
Universita degli Studi di Genova

Not yet recruiting

Neutral Versus Liberal fLuId In Traumatic Brain Injury: a Randomised Controlled Trial (LIMIT)

Traumatic Brain Injury | Fluid Overload | Outcome, Fatal
University of Reading
Unilever R&D

Not yet recruiting

Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status

Focus of Study: 1- Effect of Tea Consumption on Gut Microbiota | Focus of Study: 2- Effect of Tea Consumption on Body-iron Status

United Kingdom
University of Illinois at Chicago
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Randomized Placebo Controlled Pilot Study of Probiotic Supplementation in At-risk Pregnant Women

Stress, Psychological | Iron-deficiency | Pregnancy, High Risk

United States
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Fresh Versus Old Red Blood Cells for Transfusion

Iron, Abnormal Blood Level | Other Abnormal Blood Chemistry

United States
National Research Centre, Egypt
Cairo University

Completed

Cardiac Functions as a New Method for Evaluation of Fetal Anemia Pre and Post Intrauterine Fetal Blood Transfusion

Fetal Anemia as Antepartum Condition (Diagnosis) | Rh Incompatible Blood Transfusion Nos

Egypt
Azienda Ospedaliera S. Maria della Misericordia

Completed

Postoperative Complications After Liver Transplantation

Liver Transplantation | Postoperative Renal Complication | Postoperative Pulmonary Complication | Postoperative Cardiovascular Complication | Blood Components Transfusion

Italy
University of Sao Paulo General Hospital

Completed

Bleeding in Knee Arthroplasty After Preconditioning With Sevoflurane

Blood Loss, Surgical | Blood Transfusion

Brazil
Mongi Slim Hospital

Completed

Prevention of Bleeding in Total Joint Replacement: Combined Route Administration of Tranexamic Acid

Arthroplasty, Replacement, Knee | Blood Transfusion | Arthroplasty, Replacement, Hip | Tranexamic Acid

Tunisia
Johann Wolfgang Goethe University Hospital

Completed

Blood Loss Evaluation Using a Novel Device

Blood Loss, Surgical | Transfusion | Patient Blood Management

Germany

Clinical Trials on Transfusional Iron Overload

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