Clinical Trials on Transtibial Amputation - Unilateral in Germany

Total 80 results

RWTH Aachen University
Advanced Bionics

Completed

Cochlear Implant Electrostimulation and the Influence on the Vestibular Organ

Deafness, Bilateral | Deafness Unilateral | Deafness Congenital | Deafness, Acquired

Germany
Sonova AG

Completed

PRINCE22 System Complete Performance Study

Hearing Loss, Bilateral | Hearing Loss, Unilateral

Germany
Median
Johannes Gutenberg University Mainz

Recruiting

Passive Microprocessor-controlled Knees vs. Active Microprocessor-controlled Knees After Transfemoral Amputation

Amputation

Germany
Median
Otto Bock Healthcare Products GmbH; University Medical Center Mainz

Recruiting

Early Rehabilitation After Transfemoral Amputation in Moderately Active Patients

Transfemoral Amputation

Germany
Össur Ehf

Completed

Metabolic Cost of Walking With Passive vs. Powered Microprocessor Controlled Knees

Amputation | Prosthesis User

Germany, Iceland
Otto Bock Healthcare Products GmbH
Ottobock SE & Co. KGaA

Not yet recruiting

1C70 Feasibility Study

Amputation

Germany
MED-EL Elektromedizinische Geräte GesmbH

Completed

The BCI 602 BONEBRIDGE Post-Market Clinical Follow-up Study

Hearing Loss | Hearing Loss, Sensorineural | Hearing Loss, Bilateral | Hearing Loss, Conductive | Hearing Loss, Unilateral | Hearing Loss, Mixed

Austria, Germany, United Kingdom
Medical University of Vienna
Lund University; Helsinki University Central Hospital; Sykehuset Innlandet HF; University... and other collaborators

Completed

Comparison of Prosthetic Assessment Tools and Factors Influencing the Outcome

Amputation | Prosthesis User

Austria, Finland, Germany, Norway, Sweden
German Breast Group
Boehringer Ingelheim

Completed

Dual Blockage With Afatinib and Trastuzumab as Neoadjuvant Treatment for Patients With Locally Advanced or Operable Breast Cancer Receiving Taxane-anthracycline Containing Chemotherapy (DAFNE)

Unilateral HER2 Positive Breast Cancer

Germany
Sensorion

Completed

Efficacy of SENS-111 in Patients Suffering From Acute Unilateral Vestibulopathy

Acute Unilateral Vestibulopathy (AUV)

United States, Israel, France, Korea, Republic of, Hungary, Germany, Czechia, Italy
Hernia Center Rottenburg

Completed

Effectivity of Laparoscopic Inguinal Hernia Repair (TAPP) in Daily Clinical Practice - Early and Long-term Results

Unilateral Inguinal Hernia With Gangrene and Obstruction

Germany
Ruhr University of Bochum

Completed

The Rubber Hand Illusion (RHI) in Patients With CRPS

CRPS | Unilateral Limb Pain of Origin Other Than CRPS

Germany
University Hospital Erlangen

Recruiting

Virtual Reality in the Rehabilitation in Patients With Lower Limb Amputation.

Amputation | Rehabilitation | Activities of Daily Living | Virtual Reality | Lower Limb | Lower Extremity

Germany
German Breast Group
GlaxoSmithKline; Stemline Therapeutics, Inc.

Not yet recruiting

Evaluating the Addition of Elacestrant (Oral SERD) to Niraparib (PARP-inhibitor) in Patients With Advanced/Metastatic HR+/HER2- Breast Cancer (ELEMENT)

BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | Hormone Receptor Positive HER-2 Negative Breast Cancer | Advanced or Metastatic Breast Cancer

Germany
Marco Kesting

Recruiting

Unilateral Cleft Lip Closure - Development of a New Hybrid Technique

Complete Unilateral Cleft Lip

Germany
Charite University, Berlin, Germany

Unknown

RM-493 Treatment Trial in Proopiomelanocortin (POMC) Deficient Patients

Homozygous or Compound Heterozygous POMC, LEPR or PCSK1 Gene Mutation

Germany
MED-EL Elektromedizinische Geräte GesmbH

Completed

Feasibility of the Mi2000 Totally Implantable Cochlear Implant in Severely to Profoundly Deaf Adults. (TICI)

Cochlear Implants | Sensorineural Hearing Loss, Bilateral

Belgium, Germany
Technical University of Munich

Unknown

Gated Radiotherapy in Left Sided Breast Cancer Patients (GATTUM)

Heart Diseases | Breast Neoplasm Female | Radiotherapy Side Effect

Germany
University of Erlangen-Nürnberg

Recruiting

Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate

Cleft Lip and Palate | Unilateral Cleft Lip

Germany
Otto Bock France SNC

Completed

Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)

Amputation of Hip and Thigh, Level Unspecified

Austria, France, Germany
SIFI SpA

Completed

Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION) (FUSION)

Astigmatism | Bilateral Cataract

Spain, France, Germany
Ivantis, Inc.

Completed

Safety and Efficacy Trial to Evaluate the Hydrus(TM) Implant in Subjects Undergoing Cataract Surgery. (Hydrus II)

Primary Open Angle Glaucoma | Cataract Unilateral Pending Extraction | Glaucoma, Open Angle, Pseudo-exfoliative

Germany, Italy, Netherlands, Spain
University Hospital, Essen

Unknown

Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center Study (TOKU)

Unilateral Ureteropelvic Junction Obstruction

Germany
Charite University, Berlin, Germany
Reactive Robotics GmbH

Completed

Robotic Assisted Early Mobilization in Ventilated ICU Patients (ROBEM-I)

Critical Illness | Rehabilitation | Early Ambulation | Critical Illness Polyneuromyopathy

Germany
Sebastian Bauer
Hannover Medical School; University Hospital Tuebingen; Universitätsmedizin Mannheim and other collaborators

Unknown

POETIG Trial - POnatinib After rEsisTance to Imatinib in GIST (POETIG)

GIST, Malignant | KIT Gene Mutation | KIT Exon 13 Mutation

Germany
Oticon Medical

Active, not recruiting

Clinical Investigation Study of Safety and Performance of the Sentio System.

Hearing Loss, Conductive | Hearing Loss, Unilateral | Hearing Loss, Mixed

Germany, Netherlands, United Kingdom
Ludwig-Maximilians - University of Munich

Completed

Impact of Vertigoheel® on Patients Suffering From Bilateral Vestibulopathy and Functional Dizziness (HealVertigo)

Vertigo | Bilateral Vestibulopathy | Functional Dizziness

Germany
Ruhr University of Bochum

Completed

Correlation Between 3 Phase Bone Scintigraphy and Pressure Pain Thresholds in Patients With Complex Regional Pain Syndrome (CRPS)

Healthy Subjects | Complex Regional Pain Syndrome Type I of the Upper Limb | Unilateral Limb Pain of Other Origin

Germany
Boehringer Ingelheim

Active, not recruiting

A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation)

Solid Tumors, KRAS Mutation; SOS1

United States, Netherlands, Germany
iOMEDICO AG
Roche Pharma AG

Active, not recruiting

Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion (REALTRK)

NTRK Family Gene Mutation

Switzerland, Germany
Cochlear
Avania; QbD Clinical

Not yet recruiting

Performance and Hearing-related Outcomes in Adults Implanted With the CI622D Dexamethasone-eluting Cochlear Implant Compared to Those Implanted With a Standard Cochlear Implant (CI622) (DETECT)

Hearing Loss, Sensorineural | Hearing Loss, Bilateral | Hearing Loss, Cochlear | Hearing Loss, Bilateral Sensorineural

France, United Kingdom, Australia, Germany
APrevent Biotech GmbH

Recruiting

APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study

Paralysis, Unilateral, Vocal Cord

Austria, United States, Germany
Akouos, Inc.
Eli Lilly and Company

Recruiting

Otoferlin Gene-mediated Hearing Loss Natural History Study

Sensorineural Hearing Loss, Bilateral

United States, Taiwan, Germany, Spain, Australia, United Kingdom
Novartis Pharmaceuticals

Completed

Safety, Efficacy, Pharmacokinetics, Pharmacodynamics of ACZ885 in Patients With NALP3 Mutations and Clinical Symptoms

NALP3 Mutation

United Kingdom, France, Germany, India, Spain
OMRIX Biopharmaceuticals

Unknown

Pilot Study Evaluating the Safety and Potential Trends in Efficacy of Adhexil

Bilateral Ovarian Disease

United States, Spain, United Kingdom, Germany
AO Clinical Investigation and Publishing Documentation
AOCMF

Completed

Bilateral Condylar Fractures Registry (BCFx)

Bilateral Condylar Fracture of the Mandible

United States, Taiwan, Switzerland, South Africa, Finland, Slovenia, Pakistan, Spain, Germany, Malaysia, Mexico, Netherlands, Ukraine, Uruguay
HNO-Praxis Alte Post
Aerin Medical

Completed

Evaluate the Effectiveness of the Vivaer ARC Stylus for Nasal Breathing

Nasal Obstruction, Bilateral

Germany
University Hospital Tuebingen

Terminated

Evaluation of Photosensitivity in Dabrafenib or Vemurafenib Treated Metastatic Melanoma Patients - a Phase IIa/IIb Study

Metastatic Melanoma (Carrying BRAF V600 Mutation)

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Incyte Biosciences International Sàrl

Recruiting

Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements

Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Gene Translocation | FGFR2 Gene Rearrangement

Germany
AIO-Studien-gGmbH
Universitätsklinikum Hamburg-Eppendorf; Merck Serono GmbH, Germany; Pierre Fabre...

Recruiting

Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer (NeoBRAF)

Colorectal Cancer | Colon Cancer | BRAF V600 Mutation | BRAF V600E | Localized Cancer

Germany
Blueprint Medicines Corporation

Completed

(PROSPECTOR) Screening Study Evaluating the Prevalence of the KIT D816V Mutation in Patients With Systemic Mast Cell Activation

Systemic Mast Cell Activation | KIT D816V Mutation

United States, France, United Kingdom, Italy, Germany, Belgium, Spain, Switzerland
MED-EL Elektromedizinische Geräte GesmbH

Recruiting

Performance of the SPIRION Laryngeal Pacemaker in BVFP Patients With Single-sided Glottal Enlargement

Bilateral Vocal Cord Paralysis

Austria, Germany
MED-EL Elektromedizinische Geräte GesmbH

Recruiting

Performance of the SPIRION Laryngeal Pacemaker in BVFP Patients Without Glottal Enlargement

Bilateral Vocal Cord Paralysis

Austria, Germany
Pfizer
Medivation, Inc.; Myriad Genetic Laboratories, Inc.

Terminated

A Phase 2, 2-Stage, 2-Cohort Study of Talazoparib (BMN 673), in Locally Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (ABRAZO Study) (ABRAZO)

Breast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene Mutation

United States, Spain, United Kingdom, Germany, France
AIO-Studien-gGmbH
AstraZeneca

Terminated

Induction Therapy With Intercalated Tyrosine Kinase Inhibitor (TKI) and Chemotherapy in NSCLC With Activating Epidermal Growth Factor Receptor (EGFR) Mutation in Stages II-IIIB (NeoIntercal)

NSCLC | Non-squamous Non-small Cell Lung Cancer Stage II | Non-squamous Non-small Cell Lung Cancer Stage IIIA | Non-squamous Non-small Cell Lung Cancer Stage IIIB | Activating EGFR Mutation

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate the Effect of ACT-774312 in Subjects With Bilateral Nasal Polyposis

Bilateral Nasal Polyposis

Germany, Belgium
Technische Universität Dresden

Terminated

Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases (RadioCoBRIM)

Brain Metastases | Malignant Melanoma Stage IV | BRAF V600 Mutation

Germany
University of Heidelberg Medical Center
German Cancer Research Center; University Hospital Heidelberg; Array BioPharma; Coordinating Centre for Clinical Trials Heidelberg

Active, not recruiting

BRAF/MEK Inhibition in Relapsed/Refractory Multiple Myeloma (BIRMA) (GMMG-BIRMA)

Relapsed or Refractory Multiple Myeloma | Patients With BRAFV600 E or BRAFV600K Mutation

Germany
Pfizer
Medivation, Inc.

Completed

A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study) (EMBRACA)

Breast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene Mutation

Korea, Republic of, United States, Australia, Spain, Belgium, France, Ireland, Taiwan, Poland, Germany, Israel, Brazil, United Kingdom, Italy, Russian Federation, Ukraine
QED Therapeutics, Inc.
Helsinn Healthcare SA

Terminated

A Phase II, Single Arm Study of BGJ398 in Patients With Advanced Cholangiocarcinoma

FGFR2 Gene Mutation | Advanced Cholangiocarcinoma

United States, Belgium, Germany, Italy, Korea, Republic of, Russian Federation, Singapore, Spain, Taiwan, Thailand, United Kingdom

Clinical Trials on Transtibial Amputation - Unilateral in Germany

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