Clinical Trials on Trauma-induced Coagulopathy

Total 18745 results

Petra Hartmann MD Ph.D.

Not yet recruiting

Mitochondrial Dysfunction in Trauma-related Coagulopathy

Trauma Induced Coagulopathy

Hungary
Emory University

Withdrawn

An Observational Study of Early Coagulopathy, or Clotting Disorder, in Injured Patients

Trauma-induced Coagulopathy

United States
Sunnybrook Health Sciences Centre
Canadian Blood Services; National Blood Foundation; Canadian Department of National...

Completed

The Trauma- Formula-Driven Versus Lab-Guided Study (TRFL Study) (TRFL)

Hemorrhagic Shock | Trauma Coagulopathy

Canada
Zdravotnicka Zachranna Sluzba Kralovehradeckeho...
University Hospital Hradec Kralove

Unknown

Rapid Administration of Blood by HEMS in Trauma (RABBIT)

Wounds and Injuries | Trauma | Acute Coagulopathy

Czechia
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Gold Coast Hospital and Health Service
Emergency Medicine Foundation; National Blood Authority; Australian Red Cross

Unknown

Fibrinogen Early In Severe Trauma studY Junior (FEISTY Jnr)

Hemorrhage | Trauma | Coagulopathy | Pediatrics

Australia
Gold Coast Hospital and Health Service
Emergency Medicine Foundation; National Blood Authority; Australian Red Cross

Completed

Fibrinogen Early In Severe Trauma studY (FEISTY)

Trauma | Coagulopathy | Haemorrhage

Australia
Xu Li
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy (NMSICRCT)

Sepsis | Sepsis-induced Coagulopathy | Nafamostat Mesilate
Medical University Innsbruck

Terminated

RETIC Trial: Reversal of Trauma Induced Coagulopathy Using Coagulation Factor Concentrates or Fresh Frozen Plasma

Major Trauma

Austria
A.O. Ospedale Papa Giovanni XXIII

Withdrawn

Use of Viscoelastic Tests in the Treatment of Traumatic Induced Coagulopathy: a Pragmatic Randomized Clinical Trial. (VISCOTRAUMA)

Trauma, Multiple | Coagulopathy | Massive Hemorrhage

Italy
Australian and New Zealand Intensive Care Research...
Australian and New Zealand Intensive Care Society Clinical Trials Group; Australasian... and other collaborators

Recruiting

Fibrinogen Early In Severe Trauma StudY II (FEISTY II)

Trauma | Coagulopathy | Haemorrhagic Shock

Australia
Jubilee Mission Medical College and Research Institute

Completed

Hemostatic Variables In Snakebite Study (HISS)

Snake Bites | Coagulopathy, Consumption

India
University of Pennsylvania
Princeton University

Completed

Trauma Induced Coagulopathy and Inflammation (TrICI)

Trauma | Trauma Injury | Coagulopathy

United States
Karolinska University Hospital

Recruiting

Transfusion for Major Haemorrhage in Trauma - Characteristics and Outcomes

Hemorrhage | Trauma | Shock, Traumatic | Acute Coagulopathy

Sweden
University Hospital, Lille

Completed

Freeze-dried Plasma in the Initial Management of Coagulopathy in Trauma Patients (TrauCC)

Trauma | Coagulopathy

France
Centre Hospitalier Régional de la Citadelle

Completed

Evaluation of the TICCS Capacity to Identify Trauma Patients With Acute Coagulopathy and Massive Bleeding

Multiple Trauma | Massive Bleeding | Early Complication of Trauma

Belgium
University of Rochester

Completed

Evaluating URMC's Massive Transfusion Protocol (MTP-TEG)

Blood Coagulation Disorders | Trauma | Acute Coagulopathy

United States
University of Zurich

Completed

Hemodilution and Coagulopathy With 3 Colloids

Dilutional Coagulopathy

Switzerland
Queen Mary University of London
Oslo University Hospital; Rigshospitalet, Denmark; Barts & The London NHS Trust; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) and other collaborators

Completed

Implementing Treatment Algorithms for the Correction of Trauma Induced Coagulopathy (iTACTIC)

Hemorrhage | Trauma | Coagulopathy

Norway, Netherlands, United Kingdom, Denmark, Germany
Mahidol University

Completed

Coagulopathy in Cardiac Surgery

Coagulopathy, Cardiac Surgery, Cardiopulmonary Bypass

Thailand
Masaryk University
Brno University Hospital

Recruiting

Incidence of Trauma Induced Coagulopathy in Patients With Prehospital Administration of Fibrinogen (TICAF)

Hemorrhage | Trauma | Coagulopathy

Czechia
University of California, Los Angeles

Unknown

Transfusion Using Stored Whole Blood

Hemorrhage | Trauma | Coagulopathy

United States
Goethe University

Unknown

Point-of-Care Testing in Coagulopathic Patients Undergoing Cardiac Surgery - a Multicenter Study (MultiPOC)

Coagulopathy During Cardiac Surgery

Germany, Austria
CSL Behring

Completed

An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N (Kcentra) Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical Procedure (BE1116_3003)

Reversal of Coagulopathy

United States, Belarus, Bulgaria, Lebanon, Romania, Russian Federation
Johns Hopkins University

Terminated

The Utility of Thromboelastography in Cirrhotic Patients Undergoing Endoscopic Procedures

Cirrhosis, Coagulopathy
The Hospital for Sick Children
Synapse B.V. Research Institute, University of Maastricht

Unknown

Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass

Platelet Function Tests | Thrombin Generation Tests | Perioperative Coagulopathy

Canada
Monash University
National Health and Medical Research Council, Australia; Health Research Council...

Completed

Pre-hospital Anti-fibrinolytics for Traumatic Coagulopathy and Haemorrhage (The PATCH Study) (PATCH)

Wounds and Injuries | Acute Coagulopathy

Australia, New Zealand
Direction Centrale du Service de Santé des Armées
Floralis; TIMC-IMAG

Recruiting

Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage (T-STORHM)

Trauma | Coagulopathy | Acute Hemorrhage

France
Sunnybrook Health Sciences Centre

Completed

Fibrinogen in the Initial Resuscitation of Severe Trauma (FiiRST) (FiiRST)

Bleeding | Trauma | Coagulopathy | Injury | Haemorrhage

Canada
Medical University of Silesia

Active, not recruiting

Impact of Balanced Crystalloid and Colloid Infusion on Haemostasis in Healthy Male Volunteers

Perioperative Hemorrhage | Dilutional Coagulopathy

Poland
Denver Health and Hospital Authority
Haemonetics Corporation

Completed

Comparison of Rapid Thrombelastography and Conventional Coagulation Testing for Haemostatic Resuscitation in Trauma

Acute Coagulopathy

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Effect of Hypocalcemia on the Outcome of Elderly Major Trauma Patients With Trauma-induced Coagulopathy

Trauma | Coagulopathy

China
Jubilee Mission Medical College and Research Institute

Completed

Waveform Analysis In Snakebite Victims With Hematotoxicity (WISH)

Coagulopathy, Consumption | Snakebite

India
Florida Atlantic University

Completed

Geriatric Head Trauma Short Term Outcomes Project (GREAT-STOP)

Fall | Head Injury | Anticoagulant-induced Bleeding

United States
University of Liege

Unknown

Impact of a Prehospital Identification of Trauma Patients in Need for Damage Control Resuscitation.

Hemorrhage | Emergencies | Trauma | Coagulopathy

Belgium
Norwegian University of Science and Technology
St. Olavs Hospital

Terminated

Trauma Registration at St. Olavs Hospital 2000-2003

Trauma, Multiple | Trauma Severity Indices | Injuries, Multiple | Norway/Epidemiology | Trauma Centers/Statistics & Numerical Data
Asahi Kasei Pharma America Corporation

Withdrawn

The Safety And Efficacy of ART-123 in Subjects With Sepsis and Coagulopathy (Scarlet2)

Sepsis and Coagulopathy
CSL Behring

Completed

Study of a Prothrombin Complex Concentrate for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Japanese Subjects

Acute Major Bleeding | Reversal of Coagulopathy

Japan
Second Affiliated Hospital, School of Medicine,...

Completed

Analysis of Current Situation and Evaluation of Trauma Treatment Training in China

Trauma Injury | Train Accident Involving Explosion, Passenger Injured | Train Collision With Streetcar, Pedestrian Injured | Train Accident Involving Burning, Passenger Injured
University of Edinburgh
CSL Behring; NHS Lothian

Completed

Fibrinogen as an Alternative to FFP in Aortic Surgery.

Coagulopathy in Patients Having Thoraco-Abdominal Aneurysm Repair

United Kingdom
The University of Queensland
Royal Brisbane and Women's Hospital

Unknown

Protective Manual Hyperinflation in Acute Mechanically Ventilated Trauma Patients

Critically Injured Mechanically Ventilated Trauma Patients

Australia
Duke University
CSL Behring

Completed

Open Label Use Of RiaStap During Aortic Reconstruction

Coagulopathic Bleeding

United States
University Hospital, Strasbourg, France

Unknown

Evaluation of Patient Analgesia After Bloc Serratus (TraumaThorax)

Thorax Traumas

France
University Hospital Center of Martinique
University Hospital, Lille

Not yet recruiting

Effects of Bothrops Spp. Snake Envenomation on Willebrand Factor Activity in Martinique and French Guiana (WBOTHROPS)

Hemorrhage | Coagulopathy | Thrombi | Snake Envenomation
University Medical Centre Ljubljana

Unknown

The Influence of Noradrenaline on Coagulation and Fibrinolysis in Severe Isolated Brain Injury

Brain Injuries, Traumatic | Coagulopathy | Coagulation Defect; Bleeding | Coagulation Defect; Acquired | Fibrinolytic Hemorrhage, Acquired
Velico Medical

Enrolling by invitation

Ascending Dose Study of FrontlineODP™ Spray Dried Plasma

Hemorrhage | Coagulopathy

United States
University of Utah

Recruiting

Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence

Anemia | Thrombocytopenia | Coagulopathy, Mild | Hypofibrinogenemia

United States
Sion Microtec Ltd.

Unknown

Safety and Efficacy Study Comparing Pad-gauze With Anti-fibrinolytic Agent Hemostopan™) to a Regular Pad-gauze

Bleeding | Coagulopathy

Israel
The Leeds Teaching Hospitals NHS Trust

Active, not recruiting

FIT Study (Functional Outcomes In Trauma Study)

Wounds and Injuries | Surgery | Rehabilitation | Orthopedic Disorder | Patient Reported Outcome Measures | Disability Evaluation | Recovery of Function | Multiple Trauma/Injuries | Trauma Centers | Trauma Severity Indices | Advanced Trauma Life Support Care

United Kingdom
Rush University Medical Center
National Institutes of Health (NIH); National Center for Advancing Translational...

Recruiting

Trauma-Focused Intervention With Women Experiencing Homelessness

Substance-Related Disorders | Substance Use | Substance Use Disorders | Psychological Trauma | Trauma and Stress Related Disorders

United States

Clinical Trials on Trauma-induced Coagulopathy

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