Clinical Trials on Trematode Infections

Total 56518 results

IRCCS Sacro Cuore Don Calabria di Negrar

Recruiting

Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach

Schistosoma Mansoni

Italy
London School of Hygiene and Tropical Medicine
Emory University; Imperial College London; Kenya Medical Research Institute; Kenya...

Completed

Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya (TUMIKIA)

Helminthiasis | Disease Transmission, Infectious | Nematode Infection

Kenya
National Institute of Allergy and Infectious Diseases...

Withdrawn

Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis

Schistosomiasis
National Institute of Allergy and Infectious Diseases...

Completed

Study of Patients With Strongyloides Stercoralis Infection

HIV Infection | Strongyloidiasis | Nematode Infection

United States
Radboud University Medical Center
London School of Hygiene and Tropical Medicine; Imperial College London; University... and other collaborators

Completed

Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires

Malaria | Schistosomiasis | Hiv Infection

Uganda
DBL -Institute for Health Research and Development
Ministry of Health, Uganda

Completed

The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda

Malaria | Schistosomiasis

Uganda
Leiden University Medical Center

Completed

Repeated Controlled Human Schistosoma Mansoni Infection

Schistosomiasis | Schistosoma Mansoni

Netherlands
Rhode Island Hospital
London School of Hygiene and Tropical Medicine; Medical Research Council; University... and other collaborators

Recruiting

Praziquantel in Children Under Age 4 (PIPS)

Schistosomiasis | Schistosomiasis Mansoni | Schistosoma Japonicum Infection

Uganda, United Kingdom
Brugmann University Hospital
Université Libre de Bruxelles

Active, not recruiting

Hookworm Immune Regulation Project (HIRP-01)

Hookworm Infection

Vietnam
Swiss Tropical & Public Health Institute
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of a New Chewable Versus the Swallowable Tablet of Mebendazole Against Hookworm (CHEW_MEB_PEMBA)

Hookworm Infections

Tanzania
Jennifer Keiser
National Centre for Parasitology, Entomology and Malaria Control, Cambodia

Completed

Efficacy and Safety of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis (StrongMoxi_KH)

Strongyloides Stercoralis Infection

Cambodia
Swiss Tropical & Public Health Institute
Institute of Tropical Medicine, Belgium; B.P. Koirala Institute of Health Sciences and other collaborators

Completed

Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders (NIDIAGDigest)

Shigellosis | Schistosomiasis | Strongyloidiasis | Dientamoebiasis | Giardiasis | Amoebiasis | Soil-transmitted Helminthiasis | Intestinal Salmonellosis | Campylobacteriosis | Aeromonas Spp. Infections | Cryptosporidium Spp. Infections

Côte D'Ivoire, Indonesia, Mali, Nepal
Baylor College of Medicine
National Institute of Allergy and Infectious Diseases (NIAID); George Washington...

Active, not recruiting

Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection

Hookworm Infections

United States
Leiden University Medical Center
Swiss Tropical & Public Health Institute; Centre Suisse de Recherches Scientifiques...

Completed

Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST) (RePST)

Schistosomiasis

Côte D'Ivoire
Merck KGaA, Darmstadt, Germany

Completed

An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni)

Schistosomiasis

Germany
National Institute of Allergy and Infectious Diseases...

Completed

Praziquantel-Pharmacokinetic Study

Schistosomiasis

Philippines
National Institute of Allergy and Infectious Diseases...

Completed

S. Japonicum and Pregnancy Outcomes

Schistosomiasis

Philippines
Alejandro Krolewiecki
Brock University; Universidad Nacional del Centro de la Provincia de Buenos... and other collaborators

Completed

Albendazole Plus High Dose Ivermectin for Trichuriasis in Pediatric Patients (HI4T)

Helminthiasis | Trichuris Infection

Argentina, Honduras
International Vaccine Institute

Recruiting

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of the Sm-p80 + GLA-SE (SchistoShield®) Candidate Vaccine in Healthy Adults in Burkina Faso and Madagascar

Schistosomiasis

Burkina Faso, Madagascar
Merck KGaA, Darmstadt, Germany

Completed

L-PZQ ODT in Schistosoma Infected Children

Schistosomiasis

Côte D'Ivoire, Kenya
University of Notre Dame
Biomedical Research Center EPLS

Active, not recruiting

Schistosomiasis in Senegal

Schistosomiasis

Senegal
Assistance Publique - Hôpitaux de Paris

Completed

Retrospective Study of Clinical Practice and Management of Imported Schistosomiasis in France (RETROBIZH)

Schistosomiasis

France
Jennifer Keiser
National Centre for Parasitology, Entomology and Malaria Control, Cambodia; National Institute of Public Health, Vientiane, Laos

Enrolling by invitation

Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis (StrongMoxi)

Strongyloides Stercoralis Infection

Cambodia, Lao People's Democratic Republic
Johns Hopkins Bloomberg School of Public Health
Universidad Peruana Cayetano Heredia

Withdrawn

Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults

Helminthiasis
IRCCS Sacro Cuore Don Calabria di Negrar

Completed

The SsRI/NIE Recombinant Antigen ELISA for the Follow up of Patients Infected by Strongyloides Stercoralis

Strongyloides Stercoralis Infection

Italy
IRCCS Sacro Cuore Don Calabria di Negrar
World Health Organization; Universidad Central del Ecuador; CECOMET (Centro de...

Completed

Evaluation of Strongyloidiasis in Ecuador: a fieLd Laboratory Accuracy Study (ESTRELLA)

Strongyloidiasis | Strongyloides Stercoralis Infection

Ecuador
Swiss Tropical & Public Health Institute
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of Ascending Dosages of Moxidectin and Moxidectin-albendazole Against Trichuris Trichiura (MOXIDOSE)

Trichuris Trichiura; Infection

Tanzania
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Completed

Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm

Hookworm Infections

Tanzania
Albert B. Sabin Vaccine Institute
London School of Hygiene and Tropical Medicine; George Washington University; Oswaldo Cruz Foundation

Terminated

Phase 1 Trial of Na-ASP-2 Hookworm Vaccine in Previously Infected Brazilian Adults

Hookworm Infection

Brazil
Pemba Ministry of Health Zanzibar

Active, not recruiting

Health Education Model Led by Community Health Volunteers.

Health Education | Schistosomiasis

Tanzania
Baylor College of Medicine
George Washington University; Makerere University Walter Reed Project

Active, not recruiting

Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults

Schistosomiasis | Schistosoma Mansoni

Uganda
Leiden University

Completed

Single-sex Controlled Human Schistosomiasis Infection: Safety and Dose Finding

Schistosomiasis | Schistosoma Mansoni

Netherlands
Jennifer Keiser
Public Health Laboratory Ivo de Carneri

Not yet recruiting

Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC (Iverped)

Hookworm Infections | Ascariasis | Trichuriasis

Tanzania
Leiden University Medical Center

Completed

Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center (CHHIL)

Necator Americanus Infection

Netherlands
Meta Roestenberg

Completed

Repeated Controlled Human Hookworm Infection (ReCHHI1)

Necator Americanus Infection

Netherlands
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Immunogenicity Study of Sm-p80 + GLA-SE (SchistoShield(R)) Vaccine in Healthy Adults

Schistosomiasis

United States
Jena University Hospital
Charite University, Berlin, Germany; Technical University of Munich; University...

Terminated

Seropositivity and Adverse Birth Events in Migrants From Bilharzia-endemic Areas (Bilharzia)

Schistosomiasis

Germany
Institut de Recherche pour le Developpement

Unknown

Monitoring Schistosome Hybrids Under Under Praziquantel Pressure (Sen_hybrids)

Schistosomiasis

Senegal
Meta Roestenberg

Completed

Detection of Schistosomiasis CAA in Travellers After High-risk Water Contact

Schistosomiasis

Netherlands
Vendsyssel Hospital
Charite University, Berlin, Germany; Umeå University; Leiden University Medical... and other collaborators

Completed

Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study

Schistosomiasis

Madagascar
Oswaldo Cruz Foundation
IDRI; Biomedical Research Center EPLS; Orygen Biotecnologia SA

Completed

Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children

Schistosomiasis

Senegal
University of Edinburgh
University of Zimbabwe

Completed

Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment

Schistosomiasis

Zimbabwe
Oswaldo Cruz Foundation
IDRI; Biomedical Research Center EPLS; Orygen Biotecnologia SA

Completed

Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions

Schistosomiasis

Senegal
University of Edinburgh
National Institute for Health Research, United Kingdom; University of Zimbabwe

Completed

Health Benefits of Repeated Treatment in Pediatric Schistosomiasis

Schistosomiasis

Zimbabwe
Oswaldo Cruz Foundation
Financiadora de Estudos e Projetos

Completed

Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis

Schistosomiasis

Brazil
DBL -Institute for Health Research and Development

Completed

Women and Children as the Focus for Control of Schistosomiasis Infections in the Irrigations Area of Burkina Faso

Schistosomiasis
PATH
Yale University; Ghana Health Services; Kintampo Health Research Centre, Ghana; Noguchi Memorial Institute for Medical Research and other collaborators

Withdrawn

Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana

Hookworm Infections

Ghana
Oxfendazole Development Group
Universidad Peruana Cayetano Heredia, Lima, Peru

Not yet recruiting

Efficacy of Oxfendazole in the Treatment of Trichuris Trichiura Infection in Adults

Trichuris Infection
Swiss Tropical & Public Health Institute
National Institute of Public Health, Vientiane, Laos

Not yet recruiting

Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis

Strongyloidiasis | Strongyloides Stercoralis Infection
Universidad Nacional de Salta
Albert B. Sabin Vaccine Institute; Fundacion Mundo Sano

Unknown

Management of Soil-transmitted Helminthiasis and Strongyloidiasis

Helminthiasis | Strongyloides Stercoralis Infection

Argentina

Clinical Trials on Trematode Infections

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