Clinical Trials on Type 1 Hyperlipoprotenemia in Germany

Total 4150 results

UniQure Biopharma B.V.

Completed

Glybera Registry, Lipoprotein Lipase Deficient (LPLD) Patients (GENIALL)

Lipoprotein Lipase Deficiency | Familial Hyperlipoproteinemia Type 1 | Familial Hyperchylomicronemia

Germany
Technische Universität Dresden
Kaneka Pharma Europe N.V.

Recruiting

Effect of Lipoprotein(a) Elimination by Lipoprotein Apheresis on Cardiovascular Outcomes (MultiSELECt)

Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia

Germany
Novartis Pharmaceuticals

Recruiting

An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) (OLE)

Hyperlipoproteinemia (a)

Germany
Novartis Pharmaceuticals

Active, not recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany

Hyperlipoproteinemia(a)

Germany
University Hospital, Bonn

Completed

A Study Comparing the Mechanisms of Action of Lifibrol and Pravastatin

Hypercholesterolemia | Hyperlipoproteinemia

Germany
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Completed

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome | Lipoprotein Lipase Deficiency | Hyperlipoproteinemia Type 1

United States, Canada, Germany, Israel, Italy, South Africa, Spain, United Kingdom, Brazil, France, Netherlands
Fresenius Medical Care Deutschland GmbH

Completed

Safety and Efficacy of the DALI LDL-adsorber and MONET Lipoprotein Filter (LINET)

Hypercholesterolemia, Familial | LIPOPROTEIN TYPES--Lp SYSTEM Lp(a) HYPERLIPOPROTEINEMIA

Germany
Charite University, Berlin, Germany

Withdrawn

Randomized Controlled Trial of Lipid Apheresis in Patients With Elevated Lipoprotein(a) (ELAILa)

Hyperlipoproteinemia(a) | Progressive Cardiovascular Disease

Germany
Ludwig-Maximilians - University of Munich

Terminated

Effect of Niacin/Laropiprant on Postprandial Lipoprotein Metabolism in Patients With Dyslipoproteinemia

Metabolic Syndrome | Hyperlipoproteinemia

Germany
University of Ljubljana, Faculty of Medicine
University Medical Centre Ljubljana; Kinderkrankenhaus auf der Bult

Completed

Universal Familial Hypercholesterolemia Screening in Children

Familial Hypercholesterolemia | Polygenic Hypercholesterolaemia

Germany, Slovenia
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH) (BioHoFH)

Lipoprotein Lipase Deficiency | Inborn Error of Lipid Metabolism | Corneal Arcus

Germany, India, Sri Lanka
Fresenius Medical Care Deutschland GmbH

Completed

Comparison of the Plasma Lipoprotein Apheresis Systems DIAMED and MONET vs. the Whole Blood Apheresis System DALI (DIAMOND-2018)

Cardiovascular Diseases | Dyslipidemias | Hypercholesterolemia, Familial

Germany
Genzyme, a Sanofi Company

Completed

A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication

Familial Hypercholesterolemia

Netherlands, France, Germany, Sweden, United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Atorvastatin Three Year Pediatric Study

Familial Hypercholesterolemia

United States, Spain, Turkey, Canada, Belgium, Germany, Greece, Hungary, Italy, Norway, Poland, Puerto Rico, Russian Federation, Slovakia, Switzerland
Amryt Pharma

Active, not recruiting

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

Homozygous Familial Hypercholesterolaemia (HoFH)

Germany, Israel, Italy, Saudi Arabia, Spain, Tunisia
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Completed

Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease

Cardiovascular Disease | Elevated Lipoprotein(a)

United States, Canada, Denmark, Germany, Netherlands
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy (ODYSSEY ESCAPE)

Heterozygous Familial Hypercholesterolemia

United States, Germany
Sanofi

Completed

Euglycemic Clamp Study Comparing Two New Insulin Glargine Formulations in Subjects With Type 1 Diabetes Mellitus

Type1 Diabetes

Germany
Sanofi

Completed

A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus

Type1 Diabetes Mellitus

Germany
Adocia

Completed

A Trial to Evaluate the Pharmacokinetic and Pharmacodynamic Properties of BioChaperone® Insulin Lispro, Fiasp® and NovoRapid® Delivered by an Insulin Pump

Type1 Diabetes Mellitus

Germany
Adocia

Completed

A Trial to Investigate the Safety and the Pharmacokinetic, Pharmacodynamic Characteristics of Two BioChaperone® Glucagon Formulations Compared to Marketed GlucaGen® in Subjects With T1DM

Type 1 Diabetes Mellitus

Germany
Helmholtz Zentrum München

Recruiting

Fr1da-/Fr1da-Plus-Study in Bavaria: Early Detection for Early Care of Type 1 Diabetes (Fr1da-Plus)

Type 1 Diabetes Mellitus

Germany
Adocia

Completed

A Trial to Assess the Efficacy and Safety of M1 Pram P037 Prandial Insulin in Subjects With Type 1 Diabetes (T1DM)

Type 1 Diabetes Mellitus

Germany
Kinderkrankenhaus auf der Bult
Hannover Medical School

Withdrawn

How to be Safe With Alcoholic Drinks in Diabetes (BEER)

Hypoglycemia | Type 1 Diabetes Mellitus

Germany
Biocon Limited
Juvenile Diabetes Research Foundation; Profil Institut für Stoffwechselforschung...

Terminated

Evaluation of Pharmacokinetics , Safety, Tolerability and Pharmacodynamics of Biocon Insulin Tregopil

Type 1 Diabetes Mellitus (T1DM)

Germany
Sanofi

Completed

Single Dose Clamp Study To Compare Concentration/Time Profile And Metabolic Activity Profile Of 2 New Formulations Of Insulin Glargine With Lantus

Type 1 Diabetes Mellitus

Germany
Regeneron Pharmaceuticals
Sanofi

Completed

Study in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ODYSSEY HoFH)

Homozygous Familial Hypercholesterolemia

United States, South Africa, Canada, Greece, Japan, Ukraine, Austria, Czechia, France, Germany, Italy, Taiwan, Turkey
Amgen

Completed

Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2 (RUTHERFORD-2)

Hyperlipidemia

Canada, France, Netherlands, United Kingdom, New Zealand, South Africa, Spain, United States, Australia, Germany, Sweden, Hong Kong, Switzerland, Norway
Helmholtz Zentrum München

Recruiting

Freder1k-Study - Testing Infants for Type 1 Diabetes Risk

Identification of Infants at Risk for Type 1 Diabetes

Germany
Merck Sharp & Dohme LLC

Completed

A Study of the Efficacy and Safety of MK-0616 (Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-008)

Hypercholesterolemia | Familial Hypercholesterolemia

United States, Germany, Japan, Korea, Republic of, Mexico, Norway, Turkey, United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of MK-0616 (Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Hypercholesterolemia | Familial Hypercholesterolemia

Colombia, Israel, Taiwan, United States, Argentina, China, Germany, Italy, Japan, Korea, Republic of, Mexico, South Africa, Spain, Turkey
Dompé Farmaceutici S.p.A

Completed

Reparixin in Pancreatic Islet Transplantation

Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus

Italy, Germany
Mannkind Corporation

Completed

PK and PD Within-Subject Variability of a Single Dose of Afrezza Inhaled Technosphere Insulin in Patients With Diabetes Mellitus Type 1 (T1DM)

Type 1 Diabetes Mellitus

Germany
Novartis Pharmaceuticals

Terminated

Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.

Familial Chylomicronemia Syndrome (FCS) (HLP Type I)

South Africa, Germany, United Kingdom, France, United States, Canada, Netherlands
Novartis Pharmaceuticals

Active, not recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia (ORION-16)

Familial Hypercholesterolemia - Heterozygous

United States, Germany, South Africa, Greece, Italy, Czechia, Taiwan, Slovakia, Turkey, France, Russian Federation, Canada, Spain, Jordan, Switzerland, Hungary, Poland, Netherlands, Norway, United Kingdom, Lebanon, Argentina, Brazil, ... and more
Kastle Therapeutics, LLC

Completed

A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol (FOCUS FH)

Hypercholesterolemia | Heterozygous Familial

United States, Italy, Poland, Ukraine, United Kingdom, Germany, Hong Kong, Taiwan, Spain, Argentina, Belgium, Israel, Malaysia, South Africa, Turkey, Netherlands, Korea, Republic of, Canada, New Zealand, Russian Federation, Brazil, Austral... and more
Hoffmann-La Roche
Roche Diagnostics

Completed

A Study Evaluating the Perception of Insertion Pain With Accu-Chek FlexLink and FlexLink Plus Insulin Pump Devices Under Real Life Conditions in Diabetic Patients.

Diabetes Mellitus Type 2, Diabetes Mellitus Type 1

Germany
Sanofi

Completed

Comparison of Sotagliflozin Prototype Tablets With Reference Tablet in Healthy Subjects

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

Germany
Adocia
Tonghua Dongbao Pharmaceutical Co.,Ltd

Completed

A Trial Comparing the Pharmacodynamics and Pharmacokinetics of BC Combo THDB0207 and Lantus® and Humalog® in Subjects With Type 1 Diabetes

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Assess a Co-formulation of an Insulin Analog and Pramlintide in Subjects With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Sanofi

Completed

Study of How Single Rising Doses of SAR161271 Are Absorbed and Act in Patients With Type 1 Diabetes Mellitus (T1DM)

Type 1 Diabetes Mellitus

Germany
Technical University of Munich
Ludwig-Maximilians - University of Munich; Technische Universität Dresden; Helmholtz...

Active, not recruiting

Fr1da Insulin Intervention

Stage 1 Diabetes Mellitus, Type 1

Germany
Sanofi

Completed

A Study to Compare Pharmacokinetics (PK) and Pharmacodynamics (PD) of SAR341402 to Insulin Aspart in Subjects With Type 1 Diabetes Mellitus

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Compare BioChaperone Insulin Lispro Formulations With US Approved Humalog® and With EU Approved Humalog® in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes

Germany
Sciema UG

Suspended

Comparative Measurement of Microcirculation and Other Parameters With the Vital USA VitalDetect™ in Patients With Diabetes Mellitus Type 1 and Type 2 Versus Healthy Participants

Diabetes Mellitus

Germany
Sanofi

Completed

A Bioequivalence Study Comparing Two Different Strengths Formulations of Insulin Lispro in Patients With Type 1 Diabetes

Type 1 Diabetes

Germany
Adocia

Completed

A Trial to Investigate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BioChaperone® Pramlintide Insulin in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Adocia

Completed

Blood Glucose Control With BioChaperone Insulin Lispro Compared to Insulin Lispro (Humalog®) After Ingestion of a Standardized Meal

Diabetes Mellitus Type 1

Germany
Adocia
Eli Lilly and Company

Completed

A Trial Investigating the Continuous Subcutaneous Insulin Infusion of a Liquid Formulation of BioChaperone Insulin Lispro in Comparison to Humalog®

Type 1 Diabetes Mellitus

Germany
Hoffmann-La Roche

Completed

Comparison of the Management of Post-prandial Hyperglycemia by Multiple Bolus Calculators

Diabetes Mellitus Type 1

Germany

Clinical Trials on Type 1 Hyperlipoprotenemia in Germany

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