Clinical Trials on Type II Diabetes in South Africa

Total 4218 results

John Hunter Children's Hospital
Sydney Children's Hospitals Network; Royal Children's Hospital; Royal North Shore... and other collaborators

Unknown

Bolus Insulin Card Calculator Randomised Controlled Study

Type 1 Diabetes

Australia
Zafgen, Inc.

Completed

Study to Assess the Effects and Safety of ZGN-1061 in Overweight and Obese Participants With Type 2 Diabetes

Type 2 Diabetes Mellitus | Overweight and Obesity

Australia, New Zealand
Pfizer

Completed

Study Of Two Dosing Regimens Of PF-04937319 Compared To An Approved Agent (Sitagliptin) In Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
University of Sydney
Allergan

Completed

Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema (SwitchDMO)

Diabetes | Diabetic Retinopathy | Diabetic Macular Edema | Diabetic Macular Oedema

Australia
Hoffmann-La Roche

Completed

A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy (CANBERRA)

Diabetic Retinopathy

United States, United Kingdom, Spain, Poland, Slovakia, Australia, Puerto Rico
NuSirt Biopharma

Completed

Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

United States
NuSirt Biopharma

Completed

An Extension Protocol to Evaluate Dose Comparisons of Leucine-Metformin Combinations in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

United States
AstraZeneca
Bristol-Myers Squibb

Completed

Safety and Efficacy of Dapagliflozin as Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States, Canada, Mexico, India, Puerto Rico, Russian Federation, South Africa
GeNeuro Australia PTY Ltd
Southern Star Research Pty Ltd.

Completed

Clinical Trial Assessing the GNbAC1 in Patients With Onset of Type 1 Diabetes Within 4 Years (RAINBOW-T1D)

Diabetes Mellitus Type 1

Australia
GlaxoSmithKline

Completed

Assess the Immune Response Following Primary Vaccination With GSK Biologicals' Tritanrix™-HepB/Hib-MenAC vs Tritanrix™-HepB/Hiberix™ Given at 6,10 & 14 Wks of Age to Infants Who Received Hepatitis B Vaccine at Birth

Diphtheria; Haemophilus Influenzae Type b; Hepatitis B; Tetanus; Whole Cell Pertussis

South Africa
John Hunter Hospital

Completed

Detection of Vascular Injury in Diabetes Through Eye and Nailfold Data (DIVIDEND) - A Pilot Study (DIVIDEND)

Type 1 Diabetes Mellitus

Australia
Carmot Therapeutics, Inc.
Carmot Australia First Pty Ltd

Recruiting

A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus

Diabetes

Australia, Mexico
Eli Lilly and Company

Completed

Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes

Diabetic Neuropathies | Diabetes Mellitus, Non-Insulin-Dependent | Diabetes Mellitus, Insulin-Dependent

United States, Spain, Hungary, Australia, Belgium, Denmark, Estonia, Germany, Israel
Medical University of South Carolina
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Cellular Therapy for Type 1 Diabetes Using Mesenchymal Stem Cells

Diabetes Mellitus, Type 1

United States
Prisma Health-Upstate

Recruiting

Self-Administered 2-Hour Oral Glucose Tolerance Test

Gestational Diabetes | Gestational Diabetes Mellitus in Pregnancy | Postpartum Disorder

United States
Takeda

Withdrawn

Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis

Type 2 Diabetes Mellitus | Chronic Kidney Disease

United States, Ukraine, Bulgaria, South Africa, Hungary, Slovakia, Poland
AstraZeneca

Completed

Study to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin in Combination With Metformin Compared to Sitagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy Alone

Type 2 Diabetes

United States, Hungary, Mexico, South Africa, Romania, Poland
Metabolic Solutions Development Company

Completed

A Placebo Controlled Safety and Efficacy Study of MSDC-0160 in Type 2 Diabetes With Active Comparator

Type 2 Diabetes Mellitus

United States
Sheffield Teaching Hospitals NHS Foundation Trust
Diabetes UK

Completed

Study of CBME in the Relief of Painful Diabetic Neuropathy

Diabetic Neuropathy | Painful

United Kingdom
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
AstraZeneca
Eli Lilly and Company

Completed

An Exploratory Study of the Effect of Treatment Interruption on Safety of Exenatide in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Italy, Korea, Republic of, Hungary, Canada, Australia
ActivX Biosciences, Inc.
Kyorin Pharmaceutical Co.,Ltd

Completed

Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetics With Inadequate Glycemic Control on Metformin Alone (Synergy104)

Type 2 Diabetes

United States, Poland, Argentina, Russian Federation, Czech Republic, South Africa, Guatemala
Sanofi

Completed

baSal BoluS Therapy in patIenTs With TypE 1 Diabetes Mellitus (SUBSTITUTE)

Diabetes Mellitus, Type 1

Tunisia, South Africa, Algeria, Argentina, Brazil, Colombia, Kuwait, Mexico, Saudi Arabia
Pfizer

Completed

A Phase 1 Single/Multiple Dose Study Of PF-06293620 To Assess Safety, Tolerability And Pharmacokinetics In Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Pfizer

Completed

A Study Of PF-05175157 In Healthy Volunteers

Diabetes Mellitus, Type 2

United States
University of Vermont
Takeda

Completed

Pioglitazone Incretin Study

Diabetes Mellitus, Type 2

United States
Novo Nordisk A/S

Completed

A Research Study, Looking at How Ryzodeg® (Insulin Degludec/Insulin Aspart) Works in People With Type 2 Diabetes in Local Clinical Practice (ARISE)

Diabetes Mellitus, Type 2

Malaysia, South Africa, Philippines, Australia, India, Saudi Arabia
GlaxoSmithKline

Terminated

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers

Diabetes Mellitus, Type 2

Australia
Pfizer

Completed

A Phase 2 Multi-Center Study To Evaluate The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist In Adults With Type 2 Diabetes And Overt Nephropathy

Diabetic Nephropathy

United States, Spain, Korea, Republic of, Australia, Hong Kong, Germany, Poland, Italy, Canada, Puerto Rico, Malaysia, Romania, Argentina, Peru
Harokopio University
Monash University; National and Kapodistrian University of Athens; University... and other collaborators

Recruiting

Promote Health With Digital Tools Among Adults With Type 2 Diabetes/Prediabetes and/or Hypertension (DigiCare4You)

Hypertension | PreDiabetes | Type 2 Diabetes

Albania, Bulgaria, Greece, Spain
Novo Nordisk A/S

Completed

Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart Twice Daily and Biphasic Insulin Aspart Twice Daily in Subjects With Type 2 Diabetes Mellitus Before, During and After Ramadan

Diabetes Mellitus, Type 2 | Diabetes

United Arab Emirates, Malaysia, India, South Africa, Algeria, Lebanon
Novo Nordisk A/S

Completed

Comparison of Insulin Detemir With NPH Insulin in Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

India, Macedonia, The Former Yugoslav Republic of, Malaysia, Turkey, Croatia, Bulgaria, Romania, Australia, South Africa, Argentina
AstraZeneca
Bristol-Myers Squibb

Completed

Evaluation of Dapagliflozin Taken Twice-daily

Type 2 Diabetes

South Africa, Germany, Hungary, Romania, Slovakia, Switzerland, Ukraine
Garvan Institute of Medical Research

Completed

Effects of Glutamine on GLP-1 and Insulin Secretion in Man

Type 2 Diabetes

Australia
Pfizer

Completed

A Study of PF-05175157 in Healthy Volunteers and Type 2 Diabetic Patients

Diabetes Mellitus, Type 2

United States
Pfizer

Completed

A Study To Evaluate The Effects Of PF-05175157 In Healthy Volunteers

Diabetes Mellitus, Type 2

United States
Zafgen, Inc.

Terminated

An Efficacy and Safety Study of Beloranib in Obese Subjects With Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes

Australia
University of Sydney
Center for Eye Research Australia

Completed

Laser Therapy Combined With Intravitreal Aflibercept vs Intravitreal Aflibercept Monotherapy (LADAMO) (LADAMO)

Diabetic Retinopathy

Australia
Antiva Biosciences

Recruiting

A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Australia, South Africa
Sanofi

Completed

Efficacy and Safety Comparison of Metformin/Glimepiride Combination Versus Each Compound Alone in New Diagnosed Type 2 Diabetes Patients (RECOMMEND)

Diabetes Mellitus, Type 2

Algeria, Colombia, Egypt, Guatemala, India, Iran, Islamic Republic of, Lebanon, Mexico, Russian Federation, South Africa, Tunisia, Turkey, Ukraine, United Arab Emirates
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia (RADICHOL 1)

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Taiwan, Brazil, Canada, South Africa, United Kingdom, Singapore
Eli Lilly and Company

Active, not recruiting

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both (SURPASS-PEDS)

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Type2 Diabetes | Metabolic Disease | T2DM (Type 2 Diabetes Mellitus) | T2D

United States, India, Australia, United Kingdom, Mexico, Brazil, Israel, France, Italy
Novo Nordisk A/S

Recruiting

A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine in Adults With Type 2 Diabetes

Diabetes, Type 2

United States, India, Spain, Poland, South Africa, Bulgaria, Germany, Japan, Puerto Rico
University of Washington
National Institute on Minority Health and Health Disparities (NIMHD); Medstar... and other collaborators

Completed

Cooking for Health

Diabetes Mellitus, Type 2

United States
Pfizer

Completed

Multiple Dose Study Of PF-05231023 In Adult Subjects Who Have Poor Lipid Control With And Without Type 2 Diabetes Mellitus

Diabetes Melliuts, Type 2

United States
Bayer

Completed

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease (FIGARO-DKD)

Diabetic Kidney Disease

Belgium, Finland, France, Spain, China, Hong Kong, Switzerland, United States, Colombia, Turkey, Greece, New Zealand, Poland, Korea, Republic of, Portugal, Taiwan, Japan, Russian Federation, Singapore, Australia, Netherlands, Sweden, Austr... and more
Prisma Health-Upstate

Terminated

Diabetic Foot Infection Antibiotic Study

Diabetic Foot Infections

United States
Sanofi
Regeneron Pharmaceuticals

Completed

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (ODYSSEY KIDS)

Hypercholesterolaemia

Norway, Russian Federation, Sweden, South Africa, Czechia, United States, Canada, France, Netherlands, Spain
Hoffmann-La Roche

Completed

An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma

Malignant Melanoma

South Africa
Pfizer

Completed

Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States, Hungary, Taiwan, Romania, India, South Africa, Philippines, Slovakia

Clinical Trials on Type II Diabetes in South Africa

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