Clinical Trials on Ulcerative Colitis, Active Severe in United Kingdom

Total 576 results

Theravance Biopharma

Completed

TD-1473 for Active Ulcerative Colitis (UC)

Ulcerative Colitis, Active Severe | Ulcerative Colitis, Active Moderate

United States, Georgia, Moldova, Republic of, Romania
Theravance Biopharma

Completed

TD-3504 SAD in Healthy Subjects and Subjects With Ulcerative Colitis (UC)

Active Mild Ulcerative Colitis, Active Moderate Ulcerative Colitis, Healthy Subjects

United States
Hull University Teaching Hospitals NHS Trust

Recruiting

Multi-centre Acute Severe Ulcerative Colitis Prospective Cohort Study (Elevate ASUC) (ELEVATE-ASUC)

Severe Ulcerative Colitis

United Kingdom
The University of Texas Health Science Center,...

Not yet recruiting

Study to Evaluate the Fecal Microbiota Transplantation (FMT) in the Treatment of Ulcerative Colitis

Active Ulcerative Colitis (UC)

United States
University of Vermont

Unknown

Fecal Microbiota Transplant in the Treatment of Ulcerative Colitis (FMTUC)

Ulcerative Colitis, Active Moderate

United States
Biogen

Completed

A Phase 2 Study of Interferon Beta-1a (Avonex®) in Ulcerative Colitis

Active Ulcerative Colitis

United States, Canada, Czech Republic, Hungary, Poland, Russian Federation, Slovakia
University of Louisville
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Pilot Study of Green Tea Extract (Polyphenon E®)in Ulcerative Colitis

Mild to Moderately Active Ulcerative Colitis

United States
Facet Biotech
PDL BioPharma, Inc.

Completed

Ulcerative Colitis Study: Study of Visilizumab in Patients With Severe Ulcerative Colitis

Severe Ulcerative Colitis

United States
Hoffmann-La Roche
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis

Moderate to Severe Ulcerative Colitis

United States, Australia, Thailand, Poland, Russian Federation, Japan, Colombia, Spain, Turkey, Romania, India, Slovakia, France, Hungary, South Africa, Belgium, Bulgaria, Germany, Italy, Mexico, Serbia, Ukraine, United Kingdom
Protagonist Therapeutics, Inc.

Completed

PN-943 in Adults With Moderate to Severe Active Ulcerative Colitis (UC)

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Severe

United States, Austria, Bulgaria, Canada, Georgia, Germany, Hungary, Italy, Korea, Republic of, Poland, Russian Federation, Serbia, Ukraine
The Leeds Teaching Hospitals NHS Trust

Unknown

Utilization of NBi in Assessing Luminal INflammaion in IBD (UNBLIND)

Ulcerative Colitis (UC)

United Kingdom
Suzhou Connect Biopharmaceuticals, Ltd.

Completed

A Study Assessing the Efficacy and Safety of CBP-307 in Subjects With Moderate to Severe Ulcerative Colitis (UC)

Moderate to Severe Ulcerative Colitis

United States, China, Pakistan, Ukraine
Guy's and St Thomas' NHS Foundation Trust
Takeda

Unknown

Investigation of the Faecal Loss of Vedolizumab and Its Role in Influencing Serum Drug Levels, Outcomes and Response in Ulcerative Colitis (FAVOUR)

Ulcerative Colitis

United Kingdom
VHsquared Ltd.

Completed

Open-label V565 Target Engagement Study

Ulcerative Colitis

United Kingdom
Cerimon Pharmaceuticals

Terminated

Basiliximab Maintenance in Ulcerative Colitis

Ulcerative Colitis

United Kingdom
Topivert Pharma Ltd

Completed

Study for Safety and Tolerability of TOP1288 Administered Rectally in Healthy and Ulcerative Colitis Subjects

Ulcerative Colitis

United Kingdom
Royal Liverpool University Hospital
Hoffmann-La Roche; University of Liverpool

Completed

Rituximab in Active Ulcerative Colitis

Ulcerative Colitis

United Kingdom
University of Dundee
National Association for Colitis and Crohn's Disease

Completed

Synbiotic Treatment of Ulcerative Colitis Patients

Ulcerative Colitis

United Kingdom
Merck Sharp & Dohme LLC

Completed

Golimumab Utilization and Impact on Ulcerative Colitis (MK-8259-032) (GO-COLITIS)

Ulcerative Colitis

United Kingdom
Royal Berkshire NHS Foundation Trust
University of Reading

Recruiting

Prebiotics in Reducing Inflammation and Clinical Endpoints in Ulcerative Colitis (PRInCE-UC) (PRInCE-UC)

Ulcerative Colitis

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

High Definition Versus Chromoendoscopy for Dysplasia Detection in Ulcerative Colitis (UC)

Ulcerative Colitis

United Kingdom
London North West Healthcare NHS Trust
Nottingham University Hospitals NHS Trust

Unknown

NBI With Magnification for Dysplasia Detection in Ulcerative Colitis

Ulcerative Colitis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Study of the Golimumab Exposure-Response Relationship Using Serum Trough Levels (GO-LEVEL)

Ulcerative Colitis

United Kingdom
Topivert Pharma Ltd

Completed

Study for Safety and Tolerability of TOP1288 Administered Orally in Healthy Subjects

Ulcerative Colitis

United Kingdom
Queen Mary University of London
Barts & The London NHS Trust

Terminated

Hypnotherapy for Prevention of Relapse in Ulcerative Colitis: a Randomised, Single-blind, Controlled Clinical Trial

Ulcerative Colitis

United Kingdom
Cardiff and Vale University Health Board

Recruiting

Non-Invasive Monitoring Through Bowel Ultrasound in Paediatric Inflammatory Bowel Disease Study (NIMBUS)

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Pediatric Ulcerative Colitis | Pediatric Crohns Disease

United Kingdom
Manchester Metropolitan University
University of Manchester

Suspended

Effects of Exercise in Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

United Kingdom
Jazz Pharmaceuticals

Completed

A Pilot Study of GWP42003 in the Symptomatic Treatment of Ulcerative Colitis (GWID10160)

Ulcerative Colitis

United Kingdom
Manchester University NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Telephone Consultation as a Substitute for Routine Out-patient Face-to-face Consultation for Children With Inflammatory Bowel Disease

Crohn's Disease | Ulcerative Colitis

United Kingdom
Linkoeping University
Karolinska University Hospital; University College London Hospitals; Göteborg...

Recruiting

Colectomy Reconstruction for Ulcerative Colitis, Ileorectal Anastomosis vs Ileal Pouch-Anal Anastomosis in Ulcerative Colitis. (CRUISE)

Inflammatory Bowel Diseases | Ulcerative Colitis | Ileostomy - Stoma

Sweden, United Kingdom
Genentech, Inc.

Completed

A Safety Study of Intravenously Administered UTTR1147A in Healthy Volunteers (HVs), Participants With Ulcerative Colitis (UC), and Participants With Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis

United Kingdom, Germany
Queen Mary University of London

Terminated

Electrical Vagal Nerve Stimulation in Ulcerative Colitis (EVASION-UC)

Ulcerative Colitis | Vagal Nerve Stimulation | Transcutaneous Vagal Nerve Stimulation

United Kingdom
Hoffmann-La Roche

Terminated

A Phase I Study Of Etrolizumab Followed By Open-Label Extension And Safety Monitoring In Pediatric Patients With Moderate To Severe Ulcerative Colitis Or Moderate To Severe Crohn's Disease (FENNEL)

Crohn's Disease | Ulcerative Colitis

Poland, United Kingdom, Belgium, Spain
National Health Service, United Kingdom

Completed

The Influence of Information Sources on Knowledge and Anxiety in Inflammatory Bowel Disease Patients

Anxiety | Crohn's Disease | Ulcerative Colitis

United Kingdom
University of Dundee
Tenovus Scotland

Completed

Antibiotics for the Treatment of Ulcerative Colitis

Colitis, Ulcerative

United Kingdom
Sigmoid Pharma

Completed

Oral Ciclosporin for Colonic Release in Ulcerative Colitis (CyCol™)

Mild to Moderate Ulcerative Colitis

United Kingdom, Ireland
Ferring Pharmaceuticals

Completed

Effectiveness of Cortiment® in Patients With Ulcerative Colitis (CORE Practice)

Ulcerative Colitis

Canada, Germany, Ireland, Italy, Netherlands, Poland, Sweden, United Kingdom
Asahi Kasei Medical Co., Ltd.
Asahi Kasei Medical Europe GmbH

Terminated

A Study of Leukocytapheresis (LCAP) in Patients With Ulcerative Colitis (UC)

Ulcerative Colitis

United Kingdom, Japan, Germany, Sweden, Israel, Czech Republic
EMD Serono
Merck Serono International SA

Completed

Safety and Efficacy of Interferon-Beta-1a (Rebif®) for Treating Subjects With Acute Symptoms of Ulcerative Colitis

Ulcerative Colitis

Sweden, Germany, Netherlands, Israel, Singapore, Switzerland, United Kingdom
Portsmouth Hospitals NHS Trust

Completed

RCT: HDWL vs Virtual Chromoendoscopy in the Detection of Intraepithelial Neoplasia in Longstanding Colitis (VIRTUOSO)

Ulcerative Colitis | Crohn's Colitis

United Kingdom
University of Edinburgh

Recruiting

Mitochondrial DAMPs as Mechanistic Biomarkers of Mucosal Inflammation in Crohn's Disease and Ulcerative Colitis (MUSIC)

Inflammatory Bowel Diseases

United Kingdom
Novartis Pharmaceuticals

Terminated

Efficacy & Safety in Moderately Active Refractory Ulcerative Colitis Patients

Ulcerative Colitis

Belgium, Hungary, Switzerland, Germany, Sweden, United Kingdom
Rise Therapeutics LLC
University of Colorado, Denver; Mayo Clinic

Recruiting

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

Ulcerative Colitis | Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic | Ulcerative Colitis Chronic Mild

United States
Istituto Clinico Humanitas

Unknown

Surgical and Oncological Outcomes in Patients With Ulcerative Colitis-associated Rectal Cancer (UC-RectalK)

Rectal Cancer | Ulcerative Colitis

Italy, United Kingdom
Boehringer Ingelheim

Completed

This Study Tests How BI 655130 Works in Patients With Active Ulcerative Colitis. The Study Also Tests How Well BI 655130 is Tolerated and Whether it Helps the Patients

Colitis, Ulcerative

Belgium, Germany, United Kingdom
Quadram Institute Bioscience
University of Jena; University of East Anglia; Wageningen University; European... and other collaborators

Completed

FishGastro Study: Fish Consumption and Gastro-Intestinal Health

Colorectal Cancer | Polyps | Ulcerative Colitis

United Kingdom, Netherlands
AbbVie

Completed

A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe it is in Participants With Moderate to Severe Ulcerative Colitis Who Failed Prior Therapy

Ulcerative Colitis (UC)

United States, Canada, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Spain, United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of MK-6194 (PT101) in Participants With Active Ulcerative Colitis (UC) (MK-6194-002)

Ulcerative Colitis

United States, Georgia, Germany, Hungary, Moldova, Republic of, Poland, Ukraine, United Kingdom
Janssen Research & Development, LLC

Suspended

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

Crohn Disease | Ulcerative Colitis

Germany, United States, United Kingdom, Belgium
Shire

Completed

Safety and Pharmacokinetics of MMX Mesalamine in Children and Adolescents With Ulcerative Colitis

Ulcerative Colitis

United States, United Kingdom, Australia, Poland, Slovakia

Clinical Trials on Ulcerative Colitis, Active Severe in United Kingdom

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