Clinical Trials on Undifferentiated Connective Tissue Disease

Total 58221 results

Claire Verschraegen

Completed

Nivolumab and Radiation Therapy or Ipilimumab as Adjuvant Therapy in Treating Patients With Merkel Cell Cancer

Merkel Cell Carcinoma | Pathologic Stage IIIA Merkel Cell Carcinoma AJCC v8 | Pathologic Stage IIIB Merkel Cell Carcinoma AJCC v8

United States
National Cancer Institute (NCI)

Completed

Pharmacokinetics of Ch14.18 in Younger Patients With High-Risk Neuroblastoma

Pain | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma | Neurotoxicity Syndrome

United States
National Cancer Institute (NCI)

Completed

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Patients With Advanced Neuroendocrine Tumors

Neuroendocrine Carcinoma | Carcinoma of Unknown Primary | Neuroendocrine Carcinoma of the Skin

United States
Hospices Civils de Lyon

Completed

Predictive Factors of PTSD in Adults Admitted to an Emergency Service (ISSUE)

Post Traumatic Stress Disorder | Psychiatric Issue

France
National Cancer Institute (NCI)

Active, not recruiting

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Metastatic Renal Cell Carcinoma | Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Fallopian Tube Carcinoma | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage III Renal... and other conditions

United States
University of Milan

Completed

Effectiveness of Sealants and Fluoride Varnish in Caries Prevention in Children With Autism Spectrum Disorders

Dental Caries | Autistic Disorder | Pit and Fissure Caries

Italy
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Engineering Immune Organoids to Study Pediatric Cancer (IMMUNEORGANOID)

Sarcoma | Brain Tumor | Neuroblastoma | Kidney Tumor

France
Charles University, Czech Republic

Recruiting

The Use of Virtual Reality in Rehabilitation in Patients After Vestibular Schwannoma Surgery.

Acute Peripheral Vestibulopathy Following Surgical Procedure

Czechia
Hospices Civils de Lyon

Recruiting

Impact of Telemonitoring for the Management of Side Effects in Patients With Melanoma, Lung or Renal Cancer, Treated With Immunotherapy Combination of Nivolumab and Ipilimumab or Adjuvant Nivolumab Monotherapy (MONITOR)

Melanoma | Lung Cancer | Renal Cancer

France
Christoph Arnoldner

Recruiting

Cochlear Implantation After Gamma Knife Radiosurgery With eABR and Correlation to Postoperative Hearing Results - a Pilot Study

Hearing Loss | Vestibular Schwannoma

Austria
Northport Veterans Affairs Medical Center
Augusta University; University of Massachusetts, Worcester

Completed

Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal Bleeding (TAG)

Hereditary Hemorrhagic Telangiectasia | Melena | Arteriovenous Malformation | Hematochezia

United States
Multitude Therapeutics Inc.
Tigermed Consulting Co., Ltd

Recruiting

AMT-151 in Patients With Selected Advanced Solid Tumours

Ovarian Cancer | Ovarian Epithelial Cancer | Lung Adenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Endometrial Cancer | Advanced Cancer | Ovarian Clear Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial... and other conditions

China, Australia
Corporal Michael J. Crescenz VA Medical Center

Completed

Study of Default Options in Advance Directives

Idiopathic Pulmonary Fibrosis | COPD | Congestive Heart Failure | Malignancy | Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy | Other Interstitial Lung Disease Without Curative Therapy | NYHA Class IV or NYHA Class III Plus 1 Hospitalization... and other conditions

United States
Washington University School of Medicine

Recruiting

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Glioma | Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Pilocytic Astrocytoma | Mixed Oligoastrocytoma | Mixed Glioma | Optic Glioma

United States
Massachusetts General Hospital
National Cancer Institute (NCI); Dana-Farber Cancer Institute

Active, not recruiting

Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation

Astrocytoma | Brain Tumor | Ependymoma | Ganglioglioma | Low Grade Glioma

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Internal Radiation Therapy in Treating Patients With Liver Metastases From Neuroendocrine Tumors

Head and Neck Cancer | Metastatic Cancer | Pheochromocytoma | Islet Cell Tumor

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Prognostic Stage I Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Alpelisib for the Treatment of Anthracycline Refractory Triple Negative Breast Cancer With PIK3CA or PTEN Alterations

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
PT Bio Farma

Completed

Post Marketing Surveillance of Diphtheria Antitoxin (DAT)

Safety Issues

Indonesia
British Columbia Cancer Agency

Recruiting

Dynamic Whole Body Positron Emission Tomography/Computed Tomography Imaging

Prostatic Neoplasms | Prostate Cancer | Neuroendocrine Tumors | Neuroblastoma | Carcinoid Tumor | Paraganglioma

Canada
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Radiation Therapy in Preventing Liver Metastases in Patients With Uveal Melanoma Who HaveMonosomy 3 or DecisionDx Class 2 Disease and Are More Likely to Develop Liver Metastases

Iris Melanoma | Medium/Large Size Posterior Uveal Melanoma | Stage IIA Uveal Melanoma | Stage IIB Uveal Melanoma | Stage IIIA Uveal Melanoma | Stage IIIB Uveal Melanoma | Stage IIIC Uveal Melanoma

United States
National Cancer Institute (NCI)

Completed

Cixutumumab in Treating Patients With Metastatic Melanoma of the Eye

Ciliary Body and Choroid Melanoma, Medium/Large Size | Ciliary Body and Choroid Melanoma, Small Size | Iris Melanoma | Metastatic Intraocular Melanoma | Recurrent Intraocular Melanoma | Stage IV Intraocular Melanoma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases

Pain | Kidney Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Melanoma (Skin)

United States
National Cancer Institute (NCI)

Completed

Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye

Iris Melanoma | Stage IV Uveal Melanoma | Medium/Large Size Posterior Uveal Melanoma | Recurrent Uveal Melanoma | Ocular Melanoma With Extraocular Extension | Small Size Posterior Uveal Melanoma

United States, Canada
Indiana University

Completed

The Effectiveness of the Neutropenic Diet in Pediatric Oncology Patients

Sarcoma | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Neuroblastoma | Non-Hodgkins Lymphoma

United States
Ali Lari

Recruiting

Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery

Post Operative Pain | Safety Issues | Local Anesthetic Complication

Kuwait
Ohio State University

Completed

Heart Failure Insomnia Treatment Study (H-FITS)

Depression | Heart Failure | Sleep Disorder | Insomnia | Sleep Initiation and Maintenance Disorders | Anxiety | Congestive Heart Failure | Cardiac Failure | Disorders of Initiating and Maintaining Sleep

United States
Guangdong Women and Children Hospital

Unknown

The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells

Safety Issues | Effect of Drugs
Amgen

Completed

Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

Sarcoma | Lymphoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumors | Metastatic Cancer | Solid Tumors | Carcinoid | Locally Advanced

United States, Spain, Poland
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Boston Children's Hospital

Completed

Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer

Sarcoma | Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Neuroblastoma | Central Nervous System Tumor, Pediatric

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Brain and Central Nervous System Tumors

Germany
Children's Hospital Los Angeles
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Brain and Central Nervous System Tumors

United States, Canada
University of Edinburgh

Recruiting

Fibrosis in Chronic and Delayed Myocardial Infarction (FCDMI)

Aortic Stenosis | Carcinoid Syndrome | Chemotherapy Induced Systolic Dysfunction

United Kingdom
Imperial College London

Completed

Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs

Hereditary Hemorrhagic Telangiectasia | Pulmonary Arteriovenous Malformations

United Kingdom
Bar-Chama, Natan, M.D.

Recruiting

Assessing the Fertility Status of Men With Spinal Muscular Atrophy (SMA)

Fertility Issues

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions
Anagnostou, Evdokia, M.D.
The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Alberta Health services and other collaborators

Not yet recruiting

Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders (CALM)

Anxiety Disorders | Generalized Anxiety Disorder | Anxiety | Tuberous Sclerosis | ADHD | Neurodevelopmental Disorders | Autism Spectrum Disorder | Fragile X Syndrome | Social Anxiety | Social Anxiety Disorder | Agoraphobia | Tourette Syndrome | Tic Disorders | Autism | ADHD Predominantly Inattentive Type | ADHD - Combined... and other conditions

Canada
Charles University, Czech Republic

Completed

Role of Psychiatric Profile in Prehabituated Patients After Vestibular Schwannoma Surgery

Vestibular Schwannoma | Vestibular Function Disorder

Czechia
Erasmus Medical Center
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma (RECMAP)

Glioblastoma | Brain Neoplasms | Recurrent Glioblastoma | Recurrent Adult Brain Tumor | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme of Brain | Brain Neoplasms, Adult, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Switzerland, Belgium, Netherlands
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH); NRG Oncology

Active, not recruiting

Mobile Health to Improve Oral Chemotherapy Adherence Among Women With Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

RBX7455 Before Surgery for the Treatment of Operable Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
RenJi Hospital

Recruiting

Neoadjuvant Adebrelimab Plus Etoposide and Cisplatin in Neuroendocrine Bladder Carcinoma (RJBLC-NEBC001)

Bladder Cancer | Neuroendocrine Carcinoma of the Bladder

China
University of Copenhagen
Rigshospitalet, Denmark

Recruiting

Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms (PANACEA)

Neoplasms | Quality of Life | Insulin Resistance | Exercise | Body Composition | Sarcopenia | Cachexia | Physical Functional Performance | Muscle, Skeletal | Patient Reported Outcome Measures | Gastrointestinal Microbiome | Metabolism | Caregivers | Adipose Tissue | Proteomics | Mitochondria | Lipidomics | Epigenomics

Denmark
St. Louis University
Merck Sharp & Dohme LLC

Terminated

Fosaprepitant for N/V With High-dose Interleukin-2 for Metastatic Melanoma and Renal Cell Carcinoma (HDIL2/Emend)

Chemotherapy-induced Nausea and Vomiting

United States
Duke University
National Cancer Institute (NCI)

Completed

Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United States
Shanghai Simnova Biotechnology Co.,Ltd.
Shanghai Chest Hospital

Recruiting

SNC115 Injections in Patients With Recurrent/Refractory Small Cell Lung Cancer and Lung Large Cell Neuroendocrine Carcinoma

Recurrent/Refractory Small Cell Lung Cancer Lung Large Cell Neuroendocrine Carcinoma

China
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium; Curis, Inc.; Cannonball Kids' Cancer...

Active, not recruiting

Fimepinostat in Treating Brain Tumors in Children and Young Adults (PNOC016)

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Diffuse Intrinsic Pontine Glioma | Recurrent Anaplastic Astrocytoma

United States, Switzerland

Clinical Trials on Undifferentiated Connective Tissue Disease

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