Clinical Trials on Unhealthy Alcohol Use

Total 24111 results

Weill Medical College of Cornell University
National Institute of Neurological Disorders and Stroke (NINDS)

Active, not recruiting

Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls

Healthy | Parkinson Disease | REM Sleep Behavior Disorder

United States
Singapore Institute for Clinical Sciences
National University Polyclinics, Singapore; National University of Singapore

Completed

A Mobile Health-enabled Lifestyle Intervention Among Women With History of Gestational Diabetes(GDM) (Reverse-DM)

Healthy | Diabetes, Gestational | Gestational Diabetes Mellitus in Pregnancy

Singapore
Universitaire Ziekenhuizen KU Leuven

Completed

Mobile-based Lifestyle Intervention in Women With Glucose Intolerance After Gestational Diabetes (MELINDA)

Type 2 Diabetes Mellitus | Glucose Intolerance | Gestational Diabetes | Healthy Lifestyle

Belgium
Jieshi Ma

Completed

Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients With Brain Diseases

Healthy | Cerebral Hemorrhage | Cerebral Edema | Cerebral Ischemia

China
Larimar Therapeutics, Inc.
Clinilabs, Inc.

Completed

Determine Range of Tissue Frataxin Concentrations and Other Potential Biomarkers

Healthy Volunteers | Friedreich Ataxia

United States
Synlogic

Completed

Safety and Tolerability of SYNB1020-CP-001 (SYNB1020CP001)

Healthy Volunteer | Urea Cycle Disorder

United States
University of Minnesota

Completed

Cerebral Responses to Insulin Induced Hypoglycemia (1018)

Healthy | Type 1 Diabetes | Hypoglycemia Unawareness

United States
Washington University School of Medicine

Withdrawn

Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia

Cervical Cancer | Rectal Cancer | Pelvic Neoplasms | Bladder Cancer | Healthy Participants | Soft-tissue Sarcoma
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Drug Interaction Study With Protease Inhibitors

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
National Cancer Institute (NCI)

Completed

Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers

Skin Diseases | Virus Diseases | Healthy | Retinal Degeneration | Muscular Dystrophy

United States
Butler Hospital
National Cancer Institute (NCI)

Completed

Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Lisa Sanderson Cox, PhD
National Cancer Institute (NCI)

Completed

Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Roswell Park Cancer Institute

Completed

Bupropion in Helping Adults Stop Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Fundacio Salut i Envelliment UAB

Not yet recruiting

Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People (EFICIS)

Depressive Symptoms | Hearing Loss | Cognitive Decline | Visual Impairment | Nutrition, Healthy | Mobility
University of Milan

Recruiting

Substitution of Sulfonylureas With New Generation of Hypoglycemic Drugs for the Treatment of Type 2 Diabetes Mellitus (Sulfa-Zero)

Albuminuria | Renal Function Disorder | Diet, Healthy | T2DM (Type 2 Diabetes Mellitus)

Italy
Case Western Reserve University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Recruiting

Project 2 Airway Potential Hydrogen (pH) in Asthma

Healthy | Asthma | Cystic Fibrosis | Severe Persistent Asthma

United States
Heidelberg University

Recruiting

International (Pediatric) Peritoneal Biobank

Healthy | Kidney Failure, Chronic | Transplantation | Peritoneal Dialysis Complication

United States, Austria, Belgium, Czechia, France, Germany, Hungary, Italy, Lithuania, Malaysia, Poland, Spain, Sweden, Switzerland, Turkey
National Cancer Institute (NCI)

Completed

An Exploratory Evaluation of Biomarkers in Blister Fluid in Healthy Volunteers and Irradiated Skin

Breast Cancer | Prostate Cancer | Healthy Volunteer

United States
Istituti Clinici Scientifici Maugeri SpA
Istituto Universitario di Studi Superiori Pavia

Completed

Executive Functioning and Sleep Fragmentation in COVID-19 Patients

COVID-19 | Healthy Volunteers

Italy
Guido A. Davidzon, MD, SM

Completed

[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers

Glioblastoma | Healthy Subject | Intracranial Neoplasm

United States
Sun Pharma Advanced Research Company Limited

Active, not recruiting

Safety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML Therapies

Healthy (For Part A) | Chronic Myeloid Leukemia (for Part B and C)

United States, Spain, Hungary, Italy, India, Belgium, France, Romania, Singapore, United Kingdom, Korea, Republic of, Turkey
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Glucose Counterregulation in Long Standing Type 1 Diabetes

Healthy | Type 1 Diabetes | Hypoglycemia Unawareness

United States
Bristol-Myers Squibb

Terminated

BMS-986325 in Healthy Participants and Participants With Primary Sjögren's Syndrome

Healthy Participants | Primary Sjögren's Syndrome

Germany, United States
University of Nottingham

Active, not recruiting

Phenotyping of Adult Crohn's Focusing on Sarcopenia (PACS)

Inflammatory Bowel Diseases | Sarcopenia | Crohn Disease | Digestive System Disease | Nutrition, Healthy | Protein Malabsorption

United Kingdom
Novo Nordisk A/S

Terminated

A Multi-centre, Open Labelled, Multiple Dosing Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC 0172-2021 Administered Subcutaneously to Healthy Male Subjects and Haemophilia Subjects (explorer™2)

Healthy | Congenital Bleeding Disorder | Haemophilia A

Austria, Spain, United Kingdom, France, Germany
Slovak Academy of Sciences
National Cheng Kung University; Comenius University; University Hospital Bratislava

Unknown

Molecular Mediators of Physical Exercise and Carnosine Induced Effects in Patients With Preclinical and Early Stage Neurodegenerative Disease

Parkinson Disease | Healthy Volunteers | Mild Cognitive Impairment | Subjective Cognitive Impairment

Slovakia, Taiwan
Biogen

Completed

A Longitudinal, Observational Biomarker Study in Participants With Primary Sjogren's Syndrome

Healthy | Sjögren's Syndrome | Sicca Syndrome

United States
GlaxoSmithKline

Completed

Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Hormone Replacement in Young Women With Premature Ovarian Failure

Healthy | Osteoporosis | Premature Ovarian Failure

United States
Brock University

Not yet recruiting

Mad Dog Cooking Class Series: Effects on Dietary Self-efficacy, Eating Behaviors and Health Outcomes

Depression | Multiple Sclerosis | Inflammation | Spinal Cord Injuries | Diet, Healthy | Adherence, Treatment

Canada
National Institute of Mental Health (NIMH)

Completed

Protein Synthesis in the Brain of Patients With Fragile X Syndrome

Healthy Volunteers | Fragile X Syndrome

United States
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs

Hyperglycemia | Obesity | Overweight | Weight Loss | PreDiabetes | Prediabetic State | Impaired Glucose Tolerance | Glucose, High Blood | Lifestyle, Healthy | Lifestyle Risk Reduction | Lifestyle, Sedentary

United States
Montreal Heart Institute

Completed

Feasibility of Prediabetes Remission in Adults With Coronary Heart Disease (DIABEPIC1)

Prediabetic State | Coronary Heart Disease | Healthy Lifestyle | Remission

Canada
Janssen Research & Development, LLC

Completed

A Single Ascending Dose Study in Healthy Participants and Multiple Ascending Dose Study of CNTO 7160 in Participants With Asthma and Participants With Atopic Dermatitis

Healthy | Asthma | Atopic Dermatitis

Germany, Belgium
Sahlgrenska University Hospital, Sweden
Chalmers University of Technology; Medfield Diagnostics

Completed

Detecting Chronic Subdural Hematoma With Microwave Technology

Healthy Volunteers | Chronic Subdural Hematoma

Sweden
Hoffmann-La Roche

Completed

Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.

Healthy Volunteer, Muscular Atrophy, Spinal

Switzerland
Karolinska Institutet

Unknown

Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD

Attention Deficit Hyperactivity Disorder | Healthy Controls | Emotional Instability Personality Disorder (Borderline Personality Disorder)
University at Buffalo
University of Pavia

Completed

Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological Diseases

Multiple Sclerosis (MS) | Clinically Isolated Syndrome (CIS) | Other Neurological Disorders (OND) | Healthy (HC)
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Relative Bioavailability Study of Two New Dolutegravir/Abacavir/Lamivudine Fixed Dose Combination Tablets

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
GlaxoSmithKline

Completed

DDI Study of Etravirine and GSK1265744

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers

Myocardial Ischemia | Coronary Disease | Healthy | Cardiomyopathy, Hypertrophic | Syndrome X

United States
King Saud University

Completed

Novel Gentic Variations Contributing to Asthma Susceptability in Saudi Arabia

Collection of Clinical Data That Will be Used in This Study and Will Form a Data Bank for Asthma in Saudi Arabia | Identify Known and NOVEL Genetic Risk Factors Contributing to Asthma Susceptibility | Study the Mechanistic Roles of the Genetic Variants Within Major Asthma Susceptibility...

Saudi Arabia
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Acceptability of Less Harmful Alternatives to Cigarettes

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Perha Pharmaceuticals
Fondation Jérôme Lejeune; European Innovation Council; France 2030 program

Recruiting

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease (LEUCETTA)

Healthy Volunteers | Down Syndrome | Alzheimer's Disease

France
Mayo Clinic
National Institute on Aging (NIA)

Recruiting

A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease

Healthy | Alzheimer Disease | Lewy Body Disease

United States
Shaare Zedek Medical Center

Recruiting

Prodromal Parkinsonian Features in GBA1 Mutation Carriers

Healthy | Gaucher Disease, Type 1

Israel
National and Kapodistrian University of Athens

Recruiting

Study of the Kinetics of Antibodies Against COVID-19 (SARS-CoV-2) and of Cellular Subpopulations of the Immune System

COVID-19 | Chronic Disease | Solid Tumor | Healthy Volunteers | Hematological Malignancies

Greece
Peking Union Medical College Hospital
GeneCast Biotechnology Co., Ltd.; Geneplus-Beijing Co. Ltd.; OrigiMed; YuceBio...

Recruiting

Hepatobiliary Tumors Tissue Samples Acquisition

Hepatocellular Carcinoma | Cholangiocarcinoma | Precancerous Condition | Liver Cancer | Biliary Tract Cancer | Gallbladder Cancer | Healthy, no Evidence of Disease | Benign Hepatobiliary Disease

China
Maastricht University Medical Center

Recruiting

COVID-19, Obesity and Lifestyle in Children (COLC)

Covid-19 | Obesity, Childhood | Children, Only | Lifestyle | Lifestyle, Healthy | Family | Overweight, Childhood

Netherlands

Clinical Trials on Unhealthy Alcohol Use

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