Clinical Trials on Unresectable Pancreatic Cancer in United States

Total 25575 results

National Cancer Institute (NCI)

Terminated

Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Metastatic Pancreatic Cancer | Histologically or Cytologically Confirmed Pancreatic Cancer | Unresectable or Borderline Resectable Pancreatic Cancer

United States
HonorHealth Research Institute

Active, not recruiting

Pre-operative Treatment for Patients With Untreated Pancreatic Cancer

Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer | Unresectable Pancreatic Cancer | Neoadjuvant Pancreatic Cancer

United States
Galera Therapeutics, Inc.

Terminated

Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer

Unresectable Pancreatic Cancer | Borderline Resectable Pancreatic Cancer | SBRT

United States, France, United Kingdom, Canada
Abramson Cancer Center at Penn Medicine

Recruiting

A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Cancer Treated With Chemoradiotherapy | Borderline Resectable Pancreatic Cancer Treated With Chemoradiotherapy

United States
National Cancer Institute (NCI)

Completed

Regional Chemotherapy in Locally Advanced Pancreatic Cancer: RECLAP Trial

Histologically or Cytologically Confirmed Pancreatic Ca | Unresectable or Borderline Resectable Pancreatic Ca

United States
Weill Medical College of Cornell University

Terminated

RFA RCT for Pancreatic or Bile Duct Cancer (RFARCT)

Cholangiocarcinoma Non-resectable | Unresectable Pancreatic Cancer

United States
Weill Medical College of Cornell University

Unknown

EUS BD vs ERCP TP for Pancreatic Cancer (BILPAL)

Pancreatic Cancer | Pancreatic Adenocarcinoma | Periampullary Cancer | Biliary Tract Neoplasms | Unresectable Pancreatic Cancer | Biliary Duct Obstruction | Periampullary Carcinoma Non-Resectable

United States
University of Utah
National Cancer Institute (NCI)

Active, not recruiting

Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER) (SHAPER)

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Borderline Resectable Pancreatic Adenocarcinoma | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | Locally Advanced Unresectable Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Ductal...

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; National Cancer Institute (NCI); Syndax Pharmaceuticals

Completed

A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma

Pancreatic Cancer | Cholangiocarcinoma | Metastatic Pancreatic Cancer | Unresectable Pancreatic Cancer | Metastatic Cholangiocarcinoma | Unresectable Cholangiocarcinoma

United States
Emory University
Ipsen; Taiho Oncology, Inc.

Recruiting

TAS102 in Combination With NAL-IRI in Advanced GI Cancers

Gastric Adenocarcinoma | Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Colorectal Adenocarcinoma | Stage IV Gastric Cancer | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Stage... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Completed

Endoscopic Biliary Co-axial Stent Placement Plus/Minus Use of Radiofrequency Ablation (RFA) for Clearance of Occluded Self Expandable Metal Stents (SEMS) in Patients With Distal Biliary Obstruction From Unresectable Biliary-pancreatic Malignancies

Pancreatic Cancer | Unresectable Biliary-pancreatic Malignancies

United States
Devalingam Mahalingam
Amgen

Withdrawn

Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancer

Pancreatic Cancer | Metastatic Pancreatic Cancer | Unresectable Pancreatic Cancer | KRAS P.G12C

United States
Medical College of Wisconsin

Active, not recruiting

Magnetic Resonance (MR) Guided, Dose-Escalated Radiation Therapy (RT) + Chemotherapy in Pancreatic Cancer

Unresectable Pancreatic Cancer

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

Pancreatic Neoplasms | Pancreas Adenocarcinoma | Pancreatic Cancer Resectable | Cancer of Pancreas | Pancreatic Cancer Non-resectable | Pancreatic Ductal Adenocarcinoma (PDAC) | Pancreatic Cancer, Adult

United States
University of Maryland, Baltimore

Active, not recruiting

Outcomes of Ablation of Unresectable Pancreatic Cancer Using the NanoKnife Irreversible Electroporation (IRE) System

Unresectable Pancreatic Cancer

United States
Kimberly Perez, MD
Novartis

Terminated

A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer | Borderline Resectable Pancreatic Adenocarcinoma

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options

Metastatic Colorectal Cancer | Metastatic Pancreatic Cancer | Unresectable Pancreatic Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Gemcitabine, Nab-paclitaxel, Durvalumab, and Oleclumab Before Surgery for the Treatment of in Resectable/Borderline Resectable Primary Pancreatic Cancer

Borderline Resectable Pancreatic Adenocarcinoma | Stage IA Pancreatic Cancer AJCC v8 | Stage IB Pancreatic Cancer AJCC v8 | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | Resectable Pancreatic Adenocarcinoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma

United States
Duke University

Completed

Gemcitabine/Nab-Paclitaxel With HIGRT in Resectable Pancreatic Cancer

Resectable Pancreatic Cancers

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study

Borderline Resectable Pancreatic Adenocarcinoma | Resectable Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Cancer | Pancreatic Cancer Metastatic | Pancreatic Cancer Stage IV | Metastatic Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Pancreatic Carcinoma | Metastatic Pancreatic Cancer | Pancreatic Cancer Non-resectable | Metastatic Pancreatic Ductal Adenocarcinoma | Pancreatic Carcinoma... and other conditions

United States
Dana-Farber Cancer Institute
Patient-Centered Outcomes Research Institute; National Cancer Institute (NCI); Alliance for Clinical Trials in Oncology

Completed

Improving Informed Consent for Palliative Chemotherapy

Metastatic Colorectal Cancer | Metastatic Pancreatic Cancer | Unresectable Pancreatic Cancer

United States
Cell Genesys

Completed

A Phase II Trial of CG 8020 and CG 2505 in Patients With Nonresectable or Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer | Nonresectable Pancreatic Cancer

United States
University of Utah
Novartis Pharmaceuticals

Recruiting

Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer (THREAD)

Metastatic Pancreatic Carcinoma | Unresectable Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage II Pancreatic Cancer

United States
University of Louisville
Norton Healthcare

Withdrawn

Bilateral Thoracoscopic Splanchnicectomy for Pain Relief in Patients With Unresectable Pancreatic Cancer

Unresectable Pancreatic Cancer

United States
National Cancer Institute (NCI)

Suspended

Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to Radiation Therapy for Localized Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Locally Advanced Pancreatic Adenocarcinoma | Locally Advanced Unresectable Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Borderline Resectable Pancreatic Adenocarcinoma | Resectable Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma

United States
Jonsson Comprehensive Cancer Center
Silicon Valley Community Foundation

Recruiting

Malnutrition Screening and Dietary Intervention to Improve Nutrition Outcomes in Patients With Unresectable Pancreatic Cancer

Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer American Joint Committee on Cancer (AJCC) v8

United States
FibroGen

Completed

A Study of Gemcitabine Plus Nab-paclitaxel With or Without FG-3019 in Participants With Locally Advanced, Unresectable Pancreatic Cancer

Pancreatic Cancer (Unresectable)

United States
H. Lee Moffitt Cancer Center and Research Institute
Varian Medical Systems

Withdrawn

Total Tumor Mapping (TTM) for Resectable Pancreatic Cancer

Pancreatic Cancer | Resectable Pancreatic Cancer

United States
Nathan Bahary, MD
National Cancer Institute (NCI); Pfizer

Terminated

Pre-Operative Trial (PGHA vs. PGH) for Resectable Pancreatic Cancer (17-134)

Pancreatic Cancer Resectable

United States
University of Maryland, Baltimore

Completed

Borderline Pancreas Study: FOLFIRINOX +SBRT (GCC 1324)

Resectable Pancreatic Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

Pancreatic Adenocarcinoma | Unresectable Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Ascorbic Acid and Combination Chemotherapy in Treating Patients With Locally Advanced or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery

Pancreatic Adenocarcinoma | Unresectable Pancreatic Carcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Chemotherapy, Stereotactic Body Radiation Therapy & Nelfinavir Mesylate in Locally Advanced Pancreatic Cancer

Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage II Pancreatic Cancer | Stage I Pancreatic Cancer | Resectable Pancreatic Carcinoma | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Incyte Corporation

Recruiting

INCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampullary Cancer

Pancreatic Cancer Metastatic | Pancreatic Cancer Non-resectable

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Ductal Adenocarcinoma

United States
Invitae Corporation
Eastern Cooperative Oncology Group

Terminated

ARTEMIS: Study of Patients With Early Stage Pancreatic Cancer Who Have Undergone Genetic Testing (ARTEMIS)

Pancreatic Cancer | Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer

United States
University of Louisville
James Graham Brown Cancer Center

Completed

Effects of Folfirinox and Stereotactic Body Radiation Therapy for Advanced Pancreatic Cancer (BCC-RAD-13)

Pancreatic Cancer Non-resectable

United States
Ashish Manne
Ohio State University; NovoCure GmbH

Recruiting

A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer

United States
Case Comprehensive Cancer Center

Recruiting

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

Resectable Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma | Pancreatic Neoplasm | Locally Advanced Pancreatic Carcinoma

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study

Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer | Poorly Differentiated Malignant Neoplasm | Undifferentiated Pancreatic Carcinoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Nathan Bahary, MD

Terminated

Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer

Borderline Resectable Pancreatic Cancer

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Novartis Pharmaceuticals; Rutgers Cancer Institute...

Withdrawn

A Pilot Study of a Hedgehog Pathway Inhibitor (LDE-225) in Surgically Resectable Pancreas Cancer

Resectable Pancreatic Cancer

United States
Western Regional Medical Center

Terminated

Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic Cancer

Stage IV Pancreatic Cancer | Pancreatic Carcinoma Non-resectable

United States
OHSU Knight Cancer Institute
Genentech, Inc.; Oregon Health and Science University; American Association for... and other collaborators

Recruiting

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Ductal Adenocarcinoma

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy

Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer American Joint Committee on Cancer v8

United States

Clinical Trials on Unresectable Pancreatic Cancer in United States

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