Clinical Trials on Unresectable Esophageal Squamous Cell Carcinoma

Total 13601 results

Innovent Biologics (Suzhou) Co. Ltd.

Completed

Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment

Esophageal Squamous Cell Carcinoma

China
Guangzhou Institute of Respiratory Disease
Jiangsu HengRui Medicine Co., Ltd.; BGI-Shenzhen

Completed

Efficacy of Neoadjuvant PD-1 Blockade Plus Chemotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Immunotherapy

China
Fudan University

Unknown

A Study of Comparing Huachansu Plus Thoracic RT Versus RT Alone For ESCC

Esophageal Squamous Cell Carcinoma

China
National Cancer Institute (NCI)

Completed

A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya

Esophageal Squamous Cell Carcinoma

Kenya
Samsung Medical Center

Withdrawn

Genome-wide Association Study

Esophageal Squamous Cell Carcinoma

Korea, Republic of
Peking University

Unknown

Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) (ECMTPneo)

Esophageal Squamous Cell Carcinoma

China
Fudan University

Completed

Study of S-1 in Combination With Radiotherapy in Esophageal Cancer

Esophageal Squamous Cell Carcinoma

China
The First Affiliated Hospital of Zhengzhou University
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase II Study of SHR-1210 vs Placebo as Consolidation Chemotherapy After Radical Concurrent Chemoradiotherapy in Locally Advanced ESCC

Esophageal Squamous Cell Carcinoma

China
Fudan University
Fujian Cancer Hospital; Affiliated Hospital of Jiangnan University; First Affiliated... and other collaborators

Completed

A Phase III Study of Comparing Paclitaxel Plus 5-Fluorouracil Versus Cisplatin Plus 5-Fluorouracil in Chemoradiotherapy for Locally Advanced Esophageal Carcinoma

Esophageal Squamous Cell Carcinoma

China
Zhejiang Cancer Hospital
Second Affiliated Hospital, School of Medicine, Zhejiang University

Completed

Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin for Stage Ⅱ-Ⅲ Esophageal Cancer Patients (nabPCESCC)

Esophageal Squamous Cell Carcinoma

China
Fudan University
Zhejiang Cancer Hospital; The First Affiliated Hospital of Anhui Medical University and other collaborators

Unknown

Is ENI Necessary For Patients With Thoracic Esophageal Cancer After Esophagectomy And With Pathological Stage Of T1-2,N+,M0

Esophageal Squamous Cell Carcinoma

China
Samsung Medical Center

Completed

Phase II Trial of XP Versus XG in Advanced Esophageal Squamous Cell Carcinoma

Advanced or Recurrent Esophageal Squamous Cell Carcinoma

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Nimotuzumab Concurrent With Chemoradiotherapy for Patients With Unresectable Esophageal Squamous Cell Carcinoma

Esophageal Cancer | Chemotherapy | Immunotherapy | Chemoradiotherapy | Nimotuzumab

China
Zhejiang Cancer Hospital

Recruiting

Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma in the Era of Immunotherapy

Adjuvant Radiotherapy

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Serplulimab Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
Tianjin Medical University Cancer Institute and...

Recruiting

Carrelizumab Combined With Chemotherapy for Adjuvant Therapy of Esophageal Squamous Cell Carcinoma

Esophagus Cancer

China
Sun Yat-sen University

Recruiting

Anti-PD-1 Immunotherapy Combined With SBRT for Patients With Oligometastatic ESCC

Esophageal Squamous Cell Carcinoma | Oligometastatic Disease

China
Jiangsu Cancer Institute & Hospital

Recruiting

Chemoradiation Plus Tislelizumab for Conversion Therapy of Locally Nonresectable ESCC (LATE)

Chemoradiation | Esophageal Squamous Cell Carcinoma | Tislelizumab

China
Fifth Affiliated Hospital, Sun Yat-Sen University

Recruiting

Quantitative Evaluation of Metastatic Lymph Nodes With Dynamic 18F-FDG PET/CT in Patients With ESCC

Esophageal Squamous Cell Carcinoma | Positron Emission Tomography

China
Sichuan Cancer Hospital and Research Institute

Not yet recruiting

Surveillance of Peripheral Blood of Lymphocyte and Immunocyte in Neoadjuvant Therapy Patients With Esophageal Squamous Cell Carcinoma (pLINE)

Surgery | Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
Fujian Medical University Union Hospital

Recruiting

Postoperative Radiotherapy in Thoracic Esophageal Squamous Cell Carcinoma With Neoadjuvant Chemoradiotherapy

Radiation Oncology

China
Tianjin Medical University Cancer Institute and...

Active, not recruiting

Pembrolizumab Plus Paclitaxel, Cisplatin Followed by Surgery for Locally Advanced ESCC (KEYSTONE-001)

Esophageal Squamous Cell Carcinoma | Stage III

China
Sun Yat-sen University

Recruiting

Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study.

Esophageal Squamous Cell Carcinoma

China
Army Medical Center of PLA

Recruiting

A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
Sun Yat-sen University

Recruiting

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

Efficacy | Toxicity | Esophageal Squamous Cell Carcinoma

China
Guangdong Provincial People's Hospital

Recruiting

Trajectory Analysis of NLR and Its Association With Efficacy of Immunochemotherapy in ESCC.

Chemotherapy | Esophageal Squamous Cell Carcinoma | Immunotherapy

China
The First Affiliated Hospital of Soochow University

Recruiting

Correlation Between the Efficacy of Neoadjuvant Chemotherapy Combined With Immunotherapy of Operable Thoracic Esophageal Squamous Cell Carcinoma and the Metabolites of Intestinal Flora

Esophageal Squamous Cell Carcinoma | Intestinal Flora

China
Fudan University
Fujian Cancer Hospital; Jiangsu Cancer Institute & Hospital; Ningbo No.2 Hospital and other collaborators

Recruiting

Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15)

Esophageal Squamous Cell Carcinoma | Survival | Chemoradiotherapy

China
Second Affiliated Hospital, School of Medicine,...

Active, not recruiting

Carrelizumab, Chemotherapy and Apatinib in the Neoadjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Esophageal Squamous Cell Carcinoma

China
National Taiwan University Hospital
Roche Pharma AG; Ipsen

Recruiting

Second-line Cabozantinib and Atezolizumab in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Esophageal Cancer | Metastatic Cancer | Squamous Cell Carcinoma

Taiwan
Fudan University

Recruiting

Comparing 61.2 Gy Radiotherapy Dose Versus 50.4 Gy Radiotherapy Dose for Locally Advanced Esophageal Carcinoma

Esophageal Squamous Cell Carcinoma

China
Chase Heaton, MD
Incyte Corporation; OncoSec Medical Incorporated

Terminated

Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and Epacadostat

Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma

United States
Merck KGaA, Darmstadt, Germany
Merck Ltd., India

Terminated

A Post Marketing Surveillance Study to Assess the Safety and Efficacy of Cetuximab Plus Radiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck (PMS LAD SCCHN)

Unresectable Locally Advanced Squamous Cell Carcinoma of Head and Neck | LA SCCHN

India
UMC Utrecht
University Medical Center Groningen; Amsterdam UMC, location VUmc; The Netherlands... and other collaborators

Unknown

Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer (PRIDE)

Esophageal Cancer | Esophageal Neoplasms | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma

Netherlands
Fudan University

Recruiting

Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor

Esophageal Squamous Cell Carcinoma | Oligometastatic Disease | Radiotherapy

China
Li Zhang

Recruiting

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Neoadjuvant Therapies

China
Anhui Provincial Hospital

Recruiting

Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs for Local Advanced Patients With Inoperable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Chemoradiotherapy | Immunonutrition | Inoperable

China
Shanghai Zhongshan Hospital

Recruiting

Neoadjuvant Anti-PD-1 Plus Chemotherapy in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma | Neoadjuvant Chemoimmunotherapy

China
Tongji Hospital
National Natural Science Foundation of China

Recruiting

Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center, Prospective, Open, One Arm Exploratory Clinical Study (NICCE)

Esophageal Squamous Cell Carcinoma | Neoadjuvant Therapies

China
Cancer Institute and Hospital, Chinese Academy...

Active, not recruiting

Additional Consolidative Esophagectomy for the Patients With Oligometastatic Resectable ESCC (LEO)

Esophageal Squamous Cell Carcinoma | Oligometastatic Disease

China
Tianjin Medical University Cancer Institute and...

Completed

To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy

Enteral Nutrition | Esophageal Squamous Cell Carcinoma | Chemoradiotherapy

China
Yongtao Han

Completed

Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years

Chemotherapy | Esophageal Squamous Cell Carcinoma | Radiotherapy | Esophagectomy
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes

Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage I Lung Cancer AJCC v8 | Stage IA1 Lung Cancer AJCC v8 | Stage IA2 Lung Cancer AJCC v8 | Stage IA3 Lung Cancer... and other conditions

United States
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC

Completed

Pembrolizumab in Refractory Advanced Esophageal Cancer

Esophageal Cancer | Adenocarcinoma Esophagus | Squamous Cell Esophagus Cancer

United States
Cancer Institute and Hospital, Chinese Academy...

Unknown

SHR-1210 in Combination With Apatinib and Chemotherapy in Patients With Advanced Esophageal Squamous Cell Cancer

Esophageal Squamous Cell Carcinoma

China
Jacobio Pharmaceuticals Co., Ltd.
AbbVie

Recruiting

JAB-3068 Activity in Adult Patients With Advanced Solid Tumors

Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma

China
Shanghai Zhongshan Hospital

Not yet recruiting

Sequential Preoperative Penpulimab Combined With Chemoradiotherapy(CRT) for Locally Advanced Esophageal Squamous Cell Cancer (SPEED)

Esophageal Squamous Cell Carcinoma

China
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Tang-Du Hospital

Recruiting

Neoadjuvant Therapy for Stage II-IVA Resectable Esophageal Squamous Cell

Chemotherapy | Esophageal Squamous Cell Carcinoma | PD-1 Inhibitor | Neoadjuvent

China
Yongshun Chen

Recruiting

Prediction of Lymph Node Status in Stage T1 Esophageal Squamous Cell Carcinoma（RENMIN-237）

Esophageal Squamous Cell Carcinoma

China

Clinical Trials on Unresectable Esophageal Squamous Cell Carcinoma

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