Clinical Trials on Utilization, Health Care

Total 204541 results

RemeGen Co., Ltd.

Recruiting

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Colorectal Carcinoma

Australia, China
Sociedad de Lucha Contra el Cáncer del Ecuador

Not yet recruiting

5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas

Glioma | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Central Nervous System Neoplasms | Brain Tumor | High Grade Glioma | Glioma, Malignant | Neoplasm Malignant | Photosensitizing Agents | Tumour, Residual | Brain Neoplasms, Adult, Malignant

Ecuador
Janux Therapeutics

Recruiting

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Renal Cell Carcinoma | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Colorectal Carcinoma

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer. (Ronco-Onco)

Snoring | Sleep Apnea | Oral Cancer | Oral Squamous Cell Carcinoma | Pharynx Cancer

Canada
Tyra Biosciences, Inc

Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations (SURF301)

Solid Tumor | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | FGFR3 Gene Mutation | Urinary Tract Cancer | Locally Advanced Urothelial Carcinoma | Advanced Urothelial Carcinoma | Non-muscle-invasive Bladder Cancer | FGFR3 Gene Alteration | Urinary... and other conditions

Australia, United States, France, Spain
Maastricht University Medical Center
Sun Pharmaceutical Industries Limited

Recruiting

Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study

Carcinoma | Carcinoma, Basal Cell | Skin Cancer | Basal Cell Nevus Syndrome | Neoplasms, Basal Cell | Basal Cell Carcinoma | Locally Advanced Basal Cell Carcinoma | Metastatic Basal Cell Carcinoma | Gorlin Syndrome | Basal Cell Tumor | Neoplasm of Skin

Netherlands
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Improving Phosphate Control in Children With CKD (IMPACT)

Chronic Kidney Diseases | Hyperphosphatemia | Chronic Kidney Disease-Mineral and Bone Disorder | Pediatric Kidney Disease | CKD-MBD

United Kingdom
Ashvattha Therapeutics, Inc.

Recruiting

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

Amyotrophic Lateral Sclerosis (ALS) | Multiple Sclerosis (MS) | Parkinson Disease (PD) | Alzheimer Disease (AD)

United States
University of Florida
Florida Department of Health; Orca Biosystems, Inc.

Recruiting

Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)

Acute Myeloid Leukemia | Acute Lymphoid Leukemia | Acute Undifferentiated Leukemia | Chronic Myeloid Leukemia in Myeloid Blast Crisis | Chronic Myeloid Leukemia - Accelerated Phase | Mixed Phenotype Acute Leukemia | Chronic Myeloid Leukemia in Lymphoid Blast Crisis (Diagnosis)

United States
Oslo University Hospital

Recruiting

Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders (MITRIC)

Clear Cell Renal Cell Carcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Melanoma Stage IV | Cutaneous Squamous Cell Carcinoma | MSI-High

Norway
Kymera Therapeutics, Inc.

Recruiting

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

Solid Tumors | T-cell Prolymphocytic Leukemia (T-PLL) | Non Hodgkin Lymphoma (NHL) | Peripheral T-cell Lymphoma (PTCL) | Cutaneous T-Cell Lymphoma (CTCL) | Large Granular Lymphocytic Leukemia (LGL-L)

United States
Mayo Clinic
Hopital du Sacre-Coeur de Montreal

Recruiting

PB to Treat Hereditary Nephrogenic Diabetes Insipidus, ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration (SerendipityPB1)

Autosomal Dominant Polycystic Kidney Disease | Nephrogenic Diabetes Insipidus | Acquired Nephrogenic Diabetes Insipidus | Congenital Nephrogenic Diabetes Insipidus

United States
Institut Paoli-Calmettes
Innate Pharma

Recruiting

A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors (CHANCES)

Metastatic Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Advanced Solid Tumor | Endometrial Cancer | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer | Oesophageal Cancer | Metastatic Ovary Cancer

France
Massachusetts General Hospital

Recruiting

Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

Lynch Syndrome | Genetic Predisposition to Disease | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Neoplasm | ATM Gene Mutation | MMR Mutation

United States
Sotio Biotech Inc.
SOTIO Biotech AG; SOTIO Biotech a.s.

Recruiting

BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors (DUET-1)

Hepatocellular Carcinoma | Squamous Cell Carcinoma of the Lung | Merkel Cell Carcinoma | Myxoid/Round Cell Liposarcoma

United States
Mayo Clinic

Recruiting

HEADLIGHT: Hypofractionated Proton Therapy for Head and Neck Cancers

Head and Neck Carcinoma | Metastatic Malignant Neoplasm in the Lymph Nodes | Nasal Cavity Carcinoma | Oral Cavity Carcinoma | Paranasal Sinus Carcinoma | Salivary Gland Carcinoma | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Hypopharyngeal Carcinoma | Laryngeal Carcinoma | Oropharyngeal Carcinoma and other conditions

United States
ImaginAb, Inc.

Recruiting

Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies (iPREDICT)

Melanoma | Renal Cell Carcinoma | Non Small Cell Lung Cancer | Merkel Cell Carcinoma, Unspecified

United States, Australia, Belgium, Netherlands, Switzerland, United Kingdom
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Quality of Life After COVID-19 Related Acute respIratory Distress Syndrome Among ICU Survivors Patients in Italy: the ODISSEA Study. (ODISSEA)

Quality of Life | Covid19 | Post Traumatic Stress Disorder

Italy
Huazhong University of Science and Technology
Shanghai IASO Biotechnology Co., Ltd

Not yet recruiting

Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies

Chronic Lymphocytic Leukemia (CLL) | Peripheral T-cell Lymphomas (PTCL) | CD5+ Relapsed/Refractory Hematopoietic Malignancies | Mantle Cell Lymphoma (MCL) | Diffuse Large B-cell Lymphoma (DLBCL) | Follicular Lymphoma (FL)
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Not yet recruiting

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Liposarcoma | Liver Cancer | Rhabdomyosarcoma | Wilms Tumor | Malignant Rhabdoid Tumor | Yolk Sac Tumor

United States
Peking University
Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China

Recruiting

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (VISIONARY)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Esophageal Squamous Cell Carcinoma | Biliary Tract Neoplasms | Unknown Primary Cancer | Digestive Cancer

China
Rahul Aggarwal
Merck Sharp & Dohme LLC; U.S. Army Medical Research and Development Command; Zenith...

Recruiting

ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma | Metastatic Prostate Small Cell Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

Advanced Thyroid Gland Medullary Carcinoma | Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVC Thyroid Gland Medullary...

United States
Dana-Farber Cancer Institute

Recruiting

Serial MRI Scans During Radiation Therapy (RELAY)

MRI | Glioblastoma | Esophageal Cancer | Prostate Cancer | Vulvar Cancer | Magnetic Resonance Imaging | Radiotherapy | Pediatric Glioblastoma Multiforme

United States
VA Office of Research and Development

Recruiting

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

Quality of Life | Obstructive Sleep Apnea | Elderly | COPD | Sleepiness | Sleep Apnea Syndrome | Neurocognitive Function | Overlap Syndrome | Positive Airway Pressure

United States
Incyte Biosciences International Sàrl

Recruiting

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Lymphoma | Acute Myeloid Leukemia | Leukemia | Acute Lymphoblastic Leukemia | Acute Lymphocytic Leukemia | Solid Tumors | Chronic Phase Chronic Myeloid Leukemia | Accelerated Phase Chronic Myeloid Leukemia | Blast Phase Chronic Myeloid Leukemia

Spain, Italy, France, Germany, United Kingdom, Belgium, Sweden, Denmark, Netherlands
Lawson Health Research Institute

Not yet recruiting

Comparing Vacuum-Assisted Percutaneous Excision to Open Surgical Excision for Borderline or High-Risk Breast Lesions (VAPEX)

Breast Fibroadenoma | Lobular Carcinoma in Situ | Atypical Ductal Hyperplasia | Phyllodes Breast Tumor | Atypical Lobular Hyperplasia | Flat Epithelial Atypia | Phyllodes; Fibroadenoma | Radial Scar | Breast Papilloma | Complex Sclerosing Papillary Lesion of the Breast
Institut Paoli-Calmettes
UNICANCER - Le Groupe génétique et cancer (GGC)

Recruiting

Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation (GENEPSO)

Breast Cancers | Ovarian Cancers

France
A.O. Ospedale Papa Giovanni XXIII
University of Pisa; World Society of Emergency Surgery

Recruiting

Web-based International Register of Emergency Surgery and Trauma (WIRES-T)

Trauma | Abdominal Wall Hernia | Acute Pancreatitis | Intestinal Ischemia | Acute Cholecystitis | Acute Appendicitis | Acute Diverticulitis | Foreign Bodies | Post-operative Complications | Perforated Gastro-duodenal Ulcers | Adhesive Small Bowell Occlusion | Colonic Neoplastic Emergencies | Gynecological Emergencies and other conditions

Italy
Aalborg University Hospital
Danish Study Group of Infections of the Brain

Recruiting

Central Nervous System Infections in Denmark (DASGIB)

Encephalitis | Central Nervous System Infections | Meningitis | Bacterial Meningitis | Lyme Disease | Brain Abscess | Aseptic Meningitis | Neurosyphilis | Viral Meningitis | Neuroborreliosis | Tertiary Syphilis | Cerebral Abscess

Denmark
University of Colorado, Denver

Recruiting

The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy

Klinefelter Syndrome | Trisomy X | XYY Syndrome | XXXY and XXXXY Syndrome | Xxyy Syndrome | Xyyy Syndrome | Xxxx Syndrome | Xxxxx Syndrome | Xxxyy Syndrome | Xxyyy Syndrome | Xyyyy Syndrome | Male With Sex Chromosome Mosaicism

United States
Inspirna, Inc.

Recruiting

A Study of RGX-104 in Patients With Advanced Lung & Endometrial Cancer

Lung Cancer | Endometrial Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Carcinoma | Endometrial Cancer Recurrent | Lung Cancer Recurrent

United States
DePuy Orthopaedics

Recruiting

Actis Total Hip System 2 Year Follow-up (Actis14014)

Osteoarthritis | Rheumatoid Arthritis | Congenital Hip Dysplasia | Traumatic Arthritis | Avascular Necrosis of the Femoral Head | Acute Traumatic Fracture of the Femoral Head or Neck | Certain Cases of Ankylosis | Non-union of Femoral Neck Fractures | Certain High Sub-Capital & Femoral Neck Fractures...

United States
Mayo Clinic

Recruiting

Prospective Research Rare Kidney Stones (ProRKS) (ProRKS)

Cystinuria | Hyperoxaluria | Dent Disease | Lowe Syndrome | Adenine Phosphoribosyltransferase Deficiency

United States, Canada, Iceland, Israel
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); Boehringer Ingelheim; Cystic...

Recruiting

Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

Smoking | Smoking Cessation | Chronic Obstructive Pulmonary Disease (COPD) | Idiopathic Pulmonary Fibrosis (IPF) | Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD) | Scleroderma-Associated Interstitial Lung Disease (SSC-ILD)

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Endometrial Mixed Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Stage IV Uterine Corpus Cancer AJCC v8 | Endometrial Adenocarcinoma | Endometrioid Adenocarcinoma

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas

Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Double-Expressor Lymphoma | EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise... and other conditions

United States
Genmab
BioNTech SE

Active, not recruiting

GEN1046 Safety Trial in Patients With Malignant Solid Tumors

Cervical Cancer | Squamous Cell Carcinoma of the Head and Neck | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Solid Tumors | Endometrial Carcinoma | Urothelial Carcinoma

United States, Spain, Israel, Czechia, Georgia, Italy, Poland, Turkey, Hungary, Ukraine
Chinook Therapeutics U.S., Inc.

Active, not recruiting

Atrasentan in Patients With Proteinuric Glomerular Diseases (AFFINITY)

Diabetic Kidney Disease | Focal Segmental Glomerulosclerosis | Immunoglobulin A Nephropathy | IgA Nephropathy | Diabetic Nephropathy Type 2 | Alport Syndrome

United States, Spain, Korea, Republic of, Australia, Italy, United Kingdom
University of Washington
AbbVie

Suspended

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Refractory Mixed Phenotype Acute Leukemia | Myeloid Neoplasm | Acute Biphenotypic Leukemia | Refractory Acute Biphenotypic Leukemia | Relapsed Acute Myeloid Leukemia | Mixed Phenotype Acute Leukemia | Relapsed Acute Biphenotypic Leukemia | Relapsed... and other conditions

United States
Allegheny Singer Research Institute (also known...
ElectroCore INC

Terminated

Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms (SAVIORII)

Respiratory Failure | COVID | Corona Virus Infection | Respiratory Distress Syndrome, Adult | SARS (Severe Acute Respiratory Syndrome) | ARDS, Human

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Eli Lilly and Company; James and Esther King Biomedical...

Active, not recruiting

Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma | Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Cancer | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx | Squamous Cell Carcinoma of the Paranasal...

United States
Reata, a wholly owned subsidiary of Biogen

Terminated

An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE) (EAGLE)

Chronic Kidney Diseases | Autosomal Dominant Polycystic Kidney | Alport Syndrome

United States, France, Australia, Japan, Spain, Puerto Rico
Sidney Kimmel Cancer Center at Thomas Jefferson...
Pfizer

Active, not recruiting

Sunitinib Malate or Valproic Acid in Preventing Metastasis in Patients With High-Risk Uveal Melanoma

Ciliary Body and Choroid Melanoma, Medium/Large Size | Ciliary Body and Choroid Melanoma, Small Size | Iris Melanoma | Stage IIIA Intraocular Melanoma | Stage IIIB Intraocular Melanoma | Stage IIIC Intraocular Melanoma | Stage I Intraocular Melanoma | Stage IIA Intraocular Melanoma | Stage IIB Intraocular... and other conditions

United States
AO GENERIUM

Active, not recruiting

A Phase 1 Study of GNR-051 in Subjects With Advanced Malignancies

Melanoma | Carcinoma, Renal Cell | Carcinoma, Non-Small-Cell Lung

Russian Federation
Lawson Health Research Institute

Active, not recruiting

Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.

Carcinosarcoma | Endometrioid Adenocarcinoma | Clear Cell Carcinoma | Serous Carcinoma | Dedifferentiated Carcinoma

Canada
Chulalongkorn University

Completed

Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study

Vitamin D Deficiency | Stevens-Johnson Syndrome | Maculopapular Exanthem | Drug Reaction With Eosinophilia and Systemic Symptom | Drug-Induced Rash

Thailand
Novartis Pharmaceuticals

Completed

Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored Study

Acute Lymphoblastic Leukemia (ALL) | Chronic Myelogenous Leukemia (CML) | Metastatic Gastrointestinal Stromal Tumors (GIST) | Receptor Tyrosine Kinase (KIT) Mutated Melanoma

Italy, United Kingdom, Canada, Singapore, Netherlands, France, Korea, Republic of, United States, Slovakia, Hungary, Russian Federation, Hong Kong, Spain, Israel, Sweden, Austria
Julie L. Sutcliffe, Ph.D
National Cancer Institute (NCI)

Active, not recruiting

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Metastatic Malignant Neoplasm in the Lung | Metastatic Malignant Neoplasm in the Breast | Metastatic Malignant Neoplasm in the Colon | Metastatic Malignant Neoplasm in the Rectum

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Acupuncture for the Treatment of Intravesical BCG-Related Adverse Events in High-Risk Non-muscle Invasive Bladder Cancer

Recurrent Bladder Urothelial Carcinoma | Bladder Urothelial Carcinoma In Situ | Stage 0a Bladder Cancer AJCC v8 | Stage 0is Bladder Cancer AJCC v8 | Stage I Bladder Cancer AJCC v8 | Superficial Bladder Urothelial Carcinoma

United States

Clinical Trials on Utilization, Health Care

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