Clinical Trials on Vaccine Preventable Disease in South Africa

Total 18730 results

Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects

Vaccines, Pneumococcal Conjugate Vaccine

South Africa
Dynavax Technologies Corporation

Completed

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Volunteers

Herpes Zoster | Vaccine-Preventable Diseases | Shingles

Australia
PATH
Bill and Melinda Gates Foundation; Children's Hospital Medical Center, Cincinnati and other collaborators

Completed

Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine

Rotavirus Vaccine

South Africa
PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
HIV Vaccine Trials Network
South Africa AIDS Vaccine Initiative

Completed

Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults

HIV Seronegativity | HIV Preventive Vaccine

South Africa
University of Cape Town
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV (BifIID)

Vaccine Reaction | Hiv | Microbial Colonization | Infant Development

South Africa
Shabir Madhi

Not yet recruiting

Pertussis Vaccination Among HIV-infected and HIV-uninfected Pregnant Women

dTap Vaccine

South Africa
GlaxoSmithKline

Completed

Immunogenicity and Safety of a Candidate Tuberculosis (TB) Vaccine Given to Healthy Adults in a TB-endemic Region

Tuberculosis (TB) | Tuberculosis Vaccines

South Africa
Pfizer

Completed

13vPnC Multidose Vial Safety, Tolerability and Immunogenicity Study in Healthy Infants.

Pneumococcal Vaccines

Gambia
Duke University
University of South Carolina

Completed

Increase Vaccine Uptake in Adolescent in Rural South (INVEST)

Vaccine Hesitancy

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Poliomyelitis Vaccine

South Africa
Pfizer

Completed

A Trial to Describe the Safety and Immunogenicity of MenABCWY When Administered on 2 Schedules

Meningococcal Vaccine

United States
EyeGene Inc.
Novotech (Australia) Pty Limited

Active, not recruiting

Study to Assess the Safety, Tolerability and Explore the Immunogenicity of EG-COVID and EG-COVARo in Healthy Adult Volunteers

COVID-19 Vaccine

Australia
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer-BioNTech COVID-19 Vaccine.

Covid19 Vaccine

Canada, South Africa
Pfizer

Completed

MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age

Meningococcal Vaccine

United States, Denmark, Hungary, Czechia, Poland
IDeA States Pediatric Clinical Trials Network
National Institutes of Health (NIH); University of Nebraska; University of Montana

Active, not recruiting

Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool (MoVeUP)

Telemedicine | Pediatric ALL | Vaccine Hesitancy | COVID-19 Vaccines

United States
South Australian Health and Medical Research Institute
University of Sydney; Telethon Kids Institute; Flinders University; Royal Adelaide... and other collaborators

Recruiting

Antibiotics and Vaccine Immune Responses Study (AVIRS)

Vaccine Response Impaired

Australia
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
GlaxoSmithKline
Aeras

Completed

Study to Evaluate the Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine in Adults

Tuberculosis | Tuberculosis Vaccines

South Africa, Kenya, Zambia
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS

Cryptococcal Meningitis

South Africa
Bukwang Pharmaceutical
Contera Pharma ApS

Completed

Efficacy and Safety of JM-010 in PD With Levodopa-Induced Dyskinesia (LID)

Parkinson's Disease | Levodopa Induced Dyskinesia (LID)

South Africa
Pfizer

Completed

A Trial to Describe the Immunogenicity and Safety of 2 Doses of Bivalent rLP2086 (Trumenba) and a Pentavalent Meningococcal Vaccine in Healthy Subjects >=10 to <26 Years of Age.

Meningococcal Vaccine

United States, Finland, Czechia, Poland
Penn State University
National Institute on Drug Abuse (NIDA)

Completed

Adolescent Drug and HIV Prevention in South Africa

Substance-Related Disorders | Sexually Transmitted Diseases

South Africa
French National Agency for Research on AIDS and...

Completed

Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa

HIV Infections | Tuberculosis

South Africa
Sanofi

Completed

Efficacy and Safety Study of New Ambroxol Hardboiled Lozenges in Acute Pharyngitis (DELICIOUS)

Pharyngitis

South Africa
GlaxoSmithKline

Completed

Study to Determine the Bioequivalence of Two Fixed Dose Combination (FDC) Tablet Formulations of Amlodipine and Losartan FDC5/50 and FDC5/100 Under Fasting Conditions

Hypertension

South Africa
Bial - Portela C S.A.

Completed

An Open-label, Multiple-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093

Epilepsy

South Africa
Alvotech Swiss AG

Active, not recruiting

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase Study Conducted in Healthy Volunteers

South Africa
International Partnership for Microbicides, Inc.

Active, not recruiting

Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008

HIV Infections

South Africa
Emory University
National Institute of Mental Health (NIMH); University of KwaZulu

Recruiting

Support for Adolescents Living With HIV in South Africa (InTSHA VIP)

HIV | Human Immunodeficiency Virus

South Africa
Janssen Research & Development, LLC

Completed

A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis

Osteoarthritis, Knee

South Africa
University of Washington
National Institute of Mental Health (NIMH); Wits Reproductive Health and HIV...

Completed

The PrEP (Pre-exposure Prophylaxis) SMART Study

HIV/AIDS

South Africa
Catalyst Biosciences

Completed

Study of Next-Generation Recombinant Factor IX Variant in Adult Subjects With Hemophilia B

Hemophilia B

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
Bial - Portela C S.A.

Completed

An Open-label, Single-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093

Epilepsy

South Africa
Sanofi

Completed

Immunogenicity and Safety of Pentaxim in South African Infants

Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Infections

South Africa
University of Witwatersrand, South Africa

Completed

Comparison Of Trabeculectomy Versus The Ex-PRESS Miniature Glaucoma Device In The Same Patient: A Prospective Randomized Study (XVT-USF)

Glaucoma

South Africa
The Wistar Institute

Completed

Anti-HIV Treatment Interruptions in HIV Infected Adults in South Africa

HIV Infections

South Africa
Johns Hopkins Bloomberg School of Public Health
United States Agency for International Development (USAID); University of KwaZulu and other collaborators

Completed

Safety and Efficacy of Zinc Supplementation in HIV-1-Infected Children in South Africa

HIV Infections

South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between GSK3542503 Hydrochlorothiazide + Amiloride Hydrochloride 50 mg: 5 mg Tablets and Reference Product in Healthy Adult Participants Under Fasting Conditions

Hypertension

South Africa
University of Witwatersrand, South Africa

Unknown

A Comparison of Immediate Treatment of CIN1 With Cryotherapy and 12 Month Cytology Follow up in HIV Seropositive Women

Cervical Dysplasia

South Africa
Eunice Kennedy Shriver National Institute of Child...
Columbia University; University of Witwatersrand, South Africa

Unknown

Pediatric Nevirapine Resistance Study

HIV Infections | AIDS

South Africa
Population Council
Medical Research Council; Centers for Disease Control and Prevention

Completed

Safety and Acceptability of Carraguard® in HIV Positive Women and Men

HIV Infections

South Africa
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Efficacy of HIV Post-Test Support for ANC in South Africa (SAHAPS)

Acquired Immunodeficiency Syndrome | HIV

South Africa
University of Missouri-Columbia
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

A Controlled Study of the Safety and Efficacy of Lessertia Frutescens in HIV-infected South African Adults

HIV Infections

South Africa
Tibotec BVBA

Completed

TMC207-TiDP13-C117: Interaction Study in Human Immunodeficiency Virus-type 1 (HIV-1) Infected Patients With Nevirapine (NVP)

HIV Infections

South Africa
International Partnership for Microbicides, Inc.

Completed

A Study to Assess the Pharmacokinetics of Dapivirine (TMC120) Vaginal Microbicide Gel

HIV Infections

South Africa
Hamdy A. Azim

Recruiting

PalbocIclib in PreMenopausal Women With ER Positive/HER-2 Negative MetAstatic Breast Cancer (FATIMA)

Metastatic Breast Cancer

South Africa
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

COVID-19 Treatment in South Africa

COVID-19

South Africa

Clinical Trials on Vaccine Preventable Disease in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in India

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations