Clinical Trials on Vanishing White Matter Disease in Italy

Total 75 results

IRCCS Eugenio Medea

Active, not recruiting

Evaluation of Brain Waste Clearance Pathways Using Magnetic Resonance Imaging in Pediatric Patients With White Matter Diseases

Pediatric Disorder | Glymphatic System | White Matter Disease | Perivascular Disease

Italy
IRCCS Policlinico S. Donato

Completed

White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study

Congenital Heart Disease | Aging, Premature | White Matter Hyperintensities

Italy
University of Pavia

Completed

Home Remineralization of White Spot Lesions With Two Different Toothpastes.

White Spot Lesion

Italy
Clinical Hospital Centre Zagreb
European Society of Hypertension

Unknown

Blood Pressure Control in ESH Excellence Centres (BP-CON)

White Coat Hypertension | Blood Pressure | Lifestyle Risk Reduction

Israel, Greece, Belgium, Germany, Armenia, Austria, Bulgaria, Croatia, Czechia, Estonia, Italy, Lebanon, Lithuania, Netherlands, Poland, Portugal, Romania, Serbia, Spain, Sweden, Ukraine, United Kingdom
University of Trieste

Unknown

Avastin for CNV Secondary to Pattern Dystrophy

Choroidal Neovascularization Secondary to Pattern Dystrophy

Italy
Mario Negri Institute for Pharmacological Research
A.O. Ospedale Papa Giovanni XXIII

Terminated

Tolvaptan for In-hospital Hyponatremia (INSERT)

Hyponatremia

Italy
Dompé Farmaceutici S.p.A

Completed

A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery

Ocular Discomfort

Italy
Federico II University

Completed

Low Sodium Neapolitan Pizza Prepared With Seawater: Nutritional Properties, Sensory Characteristics, Metabolic Effects

Satiety Response | Sodium Retention | Carbohydrate Metabolism

Italy
University of Roma La Sapienza

Completed

Comparative Analgesic Effects of Paracetamol/Codeine and Ibuprofen on Pain After Third Molar Surgery

To Control Pain After Third Molar Surgery

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
University of Milan

Recruiting

Change in Inflammatory State in Patients Undergoing Transcatheter Ablation of Atrial Fibrillation (POLICARDIOFA)

Inflammation | Atrial Fibrillation | Arrhythmia | Marker of Inflammation

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Unknown

Validation of a Screening Tool to Assess Dehydration in Hospitalized Older Population

Aged | Dehydration Hypertonic

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Completed

Maternal Involvement in Pain Management in NICU

Stress, Physiological | Procedural Pain | Mother-Infant Interaction | Infant, Newborn

Italy
University of Cologne

Completed

Characterisation of Neuropsychological and Motoric Performance in Patients With Hyponatremia

Hyponatremia

Germany, Spain, Italy
University of Padova

Completed

Weaning Using Noninvasive Positive Pressure Ventilation by Means of Helmet in Patients With Acute Respiratory Failure

Inadequate or Impaired Breathing Pattern or Ventilation

Italy
Mario Negri Institute for Pharmacological Research
Vifor Pharma

Recruiting

Patiromer Trial in CKD Stage IIIB to V

Hyperkalemia

Italy
University of Padova

Unknown

Evaluation of Lymphocytic Infiltrate, Dendritic Cells and Cytokines Expression in Psoriatic Lesion and Normal Skin Before and After TNF Alfa Inhibitors Therapy (ELIDACE)

Moderate to Severe Psoriasis. | Absolute Number, Density of Immune Infiltrate and Dendritic Cells and Inflammatory Cytokines Expression Pattern.

Italy
Maja Kovacevic, MD

Withdrawn

Minoxidil Dose Response Study in Females Identified Through IVD Testing as Non-Responders to 5% Topical Minoxidil

Androgenetic Alopecia | Female Pattern Hair Loss

Italy
Istituto Ortopedico Galeazzi

Recruiting

High- Versus Low-calcium Water for Bone Health

Calcium Metabolism Disorders | Bone Resorption | Water-Electrolyte Imbalance | Orthopedic Disorder | Eating, Healthy

Italy
IRCCS Policlinico S. Matteo

Recruiting

The Italian Transthyretin Amyloidosis Web-Network (ITA-WebNet)

ATTR Amyloidosis

Italy
Arcispedale Santa Maria Nuova-IRCCS

Completed

Bromfenac Versus Dexamethasone After Cataract Surgery (BVD)

Inflammation Eye

Italy
University of Roma La Sapienza

Completed

Improvement of Anorectal Function While Preserving of Inferior Mesenteric Artery Performing Left Hemicolectomy for Diverticulosis (IPIMAL)

Defecatory Disorders After Left Colonic or Rectal Resection

Italy
Università degli Studi di Sassari

Completed

Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study

Gingivitis | Caries | Plaque Ph Lowering After Use of Probiotics

Italy
Centro Cardiologico Monzino

Recruiting

Furosemide-induced Diuresis With Matched Dehydration Compared to Standard Diuretic Therapy in Patients With Acute Heart Failure and Overt Fluid Overload (MYTHOS-HF)

Acute Decompensated Heart Failure

Italy
University of Eastern Piedmont
University of Milan

Completed

Oral Peptones Load in Normocalcemic and Hypercalcemic Primary Hyperparathyroidism and Healthy Subjects

Hyperparathyroidism | Hypercalcemia

Italy
IRCCS Policlinico S. Donato

Recruiting

Epicardial Ablation in Brugada Syndrome. An Extension Study of 500 BrS.Patients

ECG Brugada Pattern

Italy
Paolo Milani

Recruiting

NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis (NOTE-ATTR)

Amyloidosis | Amyloidosis Cardiac | ATTR Amyloidosis Wild Type

Italy
University of Rome Tor Vergata

Completed

De Novo Metabolic Syndrome in Liver Transplant Patients After Immunosuppression Withdrawal

Single Transplant | 5 Years of Follow-up After Transplant, in Which an Attempt Was Made to Suspend IS

Italy
University Hospital, Basel, Switzerland
Erasmus Medical Center; Cantonal Hospital of Aarau, Switzerland; Spital Solothurn... and other collaborators

Active, not recruiting

Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia (HIT)

Hyponatremia

Germany, Switzerland, Croatia, Italy, Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Role of Day +60 WT1 Assessment on Bone Marrow in Predicting Relapse and Mortality After Allogeneic Stem Cell Transplantation

Assessment of the WT1 Expression Level on Bone Marrow Samples Collected at Day +60 After Allogeneic Stem

Italy
University of Milano Bicocca

Completed

Application of ERAS Protocol in Emergency Surgery (ERAS in CDU)

Enhanced Recovery After Surgery | Emergency Surgery

Italy
Catholic University of the Sacred Heart

Unknown

LYmphadenectomy After NeoAdjuvant Chemotherapy (LYANA)

Advanced Ovarian Cancer (Stage III or IV) After Neoadjuvant Chemotherapy

Italy
Azienda Ospedaliera Città della Salute e della...

Completed

Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status

Hyponatremia | Hyponatremia With Excess Extracellular Fluid Volume | Hyponatremia With Extracellular Fluid Depletion | Hyponatremia With Normal Extracellular Fluid Volume

Italy
Azienda Ospedaliero-Universitaria di Parma

Completed

Late Vitamin K Deficiency-related Bleeding in Neonates (VKLB): Comparison of Different Strategies to Prophylaxis (VKLB)

Late Vitamin K Deficiency-related Bleeding

Italy
Applied Biology, Inc.

Completed

Minoxidil Response Testing in Females With Female Pattern Hair Loss

Alopecia | Female Pattern Hair Loss

United States, Australia, India, Italy
University of Modena and Reggio Emilia

Not yet recruiting

PeRinatal Outcomes With ACTive Versus Expectant Management of Women With Pre-labor Rupture Of Membranes (PROACT PROM)

Rupture of Membranes; Premature | Maternal Sepsis | Distress; Fetal, Complicating Delivery | Delayed Delivery After Spontaneous or Unspecified Rupture of Membranes

Italy
Otsuka Pharmaceutical Development & Commercialization...
Syneos Health

Terminated

Study of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia

Hyponatremia

United States, United Kingdom, Italy
AstraZeneca

Completed

A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 (ENERGIZE)

Hyperkalemia

United States, Russian Federation, Italy, Denmark
Cumberland Pharmaceuticals
Parke-Davis

Completed

Study of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic Hyponatremia

Hyponatremia

Poland, United Kingdom, Germany, Spain, Belgium, France, Netherlands, Italy, Finland
University Of Perugia

Unknown

ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER. (PRO-LAPS I)

The Primary Study Objective is to Assess the Efficacy and | Safety of Extended 4-week Heparin Prophylaxis Compared to | Prophylaxis Given for 8±2 Days After Planned Laparoscopic | Surgery for Colorectal Cancer. | The Clinical Benefit Will be Evaluated as the Difference in | the Incidence of... and other conditions

Italy
BioMarin Pharmaceutical

Completed

A Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Intracerebroventricular BMN 190 in Patients With Late-Infantile Neuronal Ceroid Lipofuscinosis (CLN2) Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease

United States, Italy, Germany, United Kingdom
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Timing of Surgical PDA Ligation and Neonatal Outcomes

Patent Ductus Arteriosus | Patent Ductus Arteriosus After Premature Birth | Patent Ductus Arteriosus - Delayed Closure

Italy, United Kingdom
Alnylam Pharmaceuticals

Recruiting

Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

Polyneuropathy | Hereditary Transthyretin-mediated (hATTR) Amyloidosis

Netherlands, Spain, United States, Germany, France, Italy, Portugal
Ionis Pharmaceuticals, Inc.
AstraZeneca

Active, not recruiting

CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

United States, United Kingdom, Italy, Spain
BioMarin Pharmaceutical

Completed

A Safety, Tolerability, and Efficacy Study of Intracerebroventricular BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease | CLN2 Disorder

United States, Germany, Italy, United Kingdom
BioMarin Pharmaceutical

Completed

An Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 190 in Patients With CLN2 Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease | CLN2 Disorder

United States, Germany, Italy, United Kingdom
Pfizer

Completed

Safety And Efficacy Evaluation Of Fx-1006A In Subjects With Transthyretin Amyloidosis

ATTR-PN

United States, Germany, Argentina, Brazil, France, Italy, Portugal, Sweden
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Niguarda Hospital

Recruiting

Combined Lung Ultrasounds and Transthoracic Electrical Bioimpedance in Preterm Infants With Respiratory Distress.

Respiratory Distress Syndrome in Premature Infant | Patent Ductus Arteriosus After Premature Birth | Perinatal Morbidity

Italy
Otsuka Frankfurt Research Institute GmbH

Unknown

Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical Practice

SIADH | Non-SIADH Hyponatremia | Non-Hyponatremia

Denmark, Germany, Italy, Norway, Spain, Sweden, United Kingdom
Otsuka Pharmaceutical Development & Commercialization...
Syneos Health

Terminated

An Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Participants With Euvolemic or Hypervolemic Hyponatremia

Hyponatremia

Belgium, Spain, United States, United Kingdom, Italy, Germany, Czechia, Romania
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia

Euvolemic Hyponatremia

United States, Israel, India, Mexico, Peru, Belgium, Czech Republic, Italy

Clinical Trials on Vanishing White Matter Disease in Italy

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