Clinical Trials on Vascular Disease Occlusive in South Africa

Total 18811 results

Biopure Corporation

Terminated

Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia

Peripheral Vascular Disease

United Kingdom, South Africa
Biopure Corporation

Unknown

A Study of Hemopure® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery

Coronary Artery Disease

Greece, South Africa, United Kingdom
Silence Therapeutics plc

Active, not recruiting

Evaluate SLN360 in Participants With Elevated Lipoprotein(a) at High Risk of Atherosclerotic Cardiovascular Disease Events

Cardiovascular Diseases | Atherosclerosis | Lipoprotein(a)

Australia, Czechia, Denmark, Netherlands, Slovakia, South Africa, United Kingdom
Charles G. Prober
Stanford University; Heidelberg University; University of Stellenbosch; University...

Completed

The Philani Mobile Video Intervention for Exclusive Breastfeeding (MOVIE) Study (MOVIE)

Exclusive Breastfeeding | Infant Feeding Practices

South Africa
GlaxoSmithKline

Completed

Study to Determine the Bioequivalence of Two Fixed Dose Combination (FDC) Tablet Formulations of Amlodipine and Losartan FDC5/50 and FDC5/100 Under Fasting Conditions

Hypertension

South Africa
Sanofi

Completed

Efficacy and Safety of HMR1766 in Patients With Fontaine Stage II Peripheral Arterial Disease (ACCELA)

Intermittent Claudication

United States, France, Canada, Poland, Russian Federation, Austria, South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between GSK3542503 Hydrochlorothiazide + Amiloride Hydrochloride 50 mg: 5 mg Tablets and Reference Product in Healthy Adult Participants Under Fasting Conditions

Hypertension

South Africa
Ovalum

Terminated

Study to Evaluate the Safety and Efficacy of the CiTop™ ExPander™ Guidewire for Crossing Chronic Total Occlusions in Coronary Arteries

Coronary Chronic Total Occlusion

Germany, South Africa
Allergan

Completed

Safety and Efficacy of AGN208397 in the Treatment of Macular Edema Associated With Retinal Vein Occlusion (RVO)

Macular Edema | Retinal Vein Occlusion

South Africa, Canada, United States, Australia, Israel
University of Melbourne

Recruiting

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (POST-ETERNAL)

Basilar Artery Occlusion

Australia
University of Johannesburg

Completed

The Effect of a Homoeopathic Complex on Blood Pressure in Refractory Hypertension

Essential Hypertension

South Africa
University of Johannesburg

Completed

Venavine Intensive® in the Treatment of Symptoms Associated With Chronic Venous Insufficiency

Venous Insufficiency

South Africa
McGill University Health Centre/Research Institute...
King's College London; University of Wisconsin, Madison; University Hospital... and other collaborators

Completed

Breathing-Induced Myocardial Oxygenation Reserve (B-MORE-Pilot)

Coronary Artery Disease

United States, Germany, United Kingdom, Canada, South Africa
University of Witwatersrand, South Africa
Massachusetts General Hospital; Emory University; UMC Utrecht

Recruiting

iHEART-SA Intervention Study (iHEART-SA)

Hypertension | HIV

South Africa
C. R. Bard

Terminated

Lutonix Drug Coated Balloon for Treatment of Femoropopliteal Arteries in United States Females (CONFIRM) (CONFIRM)

Popliteal Artery Stenosis | Popliteal Artery Occlusion | Femoral Artery Occlusion | Femoral Artery Stenosis

United States
University of Johannesburg

Completed

The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous Insufficiency

Venous Insufficiency

South Africa
Brigham and Women's Hospital

Recruiting

Implementation of a Combination Intervention for Sustainable Blood Pressure Control (IMPACT-BP)

Hypertension

South Africa
University of Witwatersrand, South Africa

Terminated

Safety And Efficacy Of Topical Platelet Rich Plasma And Thrombin Coagulum

Stasis Ulcer

South Africa
University of Stellenbosch

Completed

A Cross-sectional Study on Intradialytic Hypertension at Four Haemodialysis Units in the Western Cape

Intradialytic Hypertension

South Africa
LimFlow, Inc.

Active, not recruiting

PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia (PROMISE)

Vascular Diseases | Arterial Occlusive Diseases | Peripheral Arterial Disease | Peripheral Vascular Disease | Peripheral Artery Disease | Critical Limb Ischemia | Arterial Disease | Arterial Occlusion | Critical Lower Limb Ischemia | Chronic Limb-Threatening Ischemia | Peripheral Artery Occlusion | Peripheral...

United States, Puerto Rico
North-West University, South Africa
GlaxoSmithKline; Novartis; Pfizer; Boehringer Ingelheim; Medical Research Council; Medical... and other collaborators

Active, not recruiting

The African-PREDICT Study (PREDICT)

Cardiovascular Diseases | Hypertension | Health Risk Behaviors | Arterial Stiffness | Young | Renin Hypertension

South Africa
Pace Clinic
University Hospital, Saarland

Completed

Renal Sympathetic Denervation Prevents Atrial Fibrillation in Patients With Hypertensive Heart Disease: a Pilot Study (RDPAF)

Hypertension | Atrial Fibrillation | Autonomic Imbalance | Hypertensive Heart Disease

South Africa
Nkanyiso Hadebe

Unknown

Cardiac REperfusion With Intralipid® at Reperfusion (CREW-I)

Reperfusion Injury

South Africa
Anesiva, Inc.

Completed

Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures

Ischemia | Arterial Occlusive Diseases | Peripheral Vascular Diseases | Hyperplasia | Graft Occlusion, Vascular

United States, Canada
Novartis

Completed

Safety and Efficacy of APL180 in Healthy Volunteers and Patients With Coronary Heart Disease (CHD)

Coronary Heart Disease

Netherlands, South Africa, United States, Belgium, Denmark, Israel, United Kingdom
North-West University, South Africa
Medical Research Council, South Africa; National Research Foundation of South...

Active, not recruiting

Exercise, Arterial Modulation and Nutrition in Youth South Africa Study (ExAMIN-Youth)

Hypertension | Childhood Obesity | Retinal Artery Stenosis

South Africa
Sheffield Hallam University
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Blood Flow Restricted Resistance Training in Peripheral Arterial Disease

Peripheral Arterial Disease

United Kingdom
Allergan

Completed

A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion

Macular Edema | Retinal Vein Occlusion

France, United States, Canada, Taiwan, Australia, Austria, Czechia, Portugal, Germany, Israel, Philippines, Mexico, South Africa
University of Cape Town
Mayo Clinic; University of Lagos, Nigeria; University of Ibadan; Aminu Kano Teaching... and other collaborators

Completed

The Pan African Pulmonary Hypertension Cohort Study (PAPUCO)

Pulmonary Hypertension

South Africa
University of Stellenbosch
Columbia University; McMaster University

Active, not recruiting

Mobile Phone Text Messaging Plus Motivational Interviewing: Effects on Breastfeeding, Child Health Outcomes (MTM-MI)

HIV Infections | Breastfeeding, Exclusive

South Africa
Alucent Biomedical

Active, not recruiting

Feasibility Study of the Vessel Restoration System (VRS): ACTIVATE II (ACTIVATEII)

PAD - Peripheral Arterial Disease

Australia
Novo Nordisk A/S

Completed

An International Chart Review and Survey for the Prevalence and Clinical Management of Atherosclerotic Cardiovascular Diseases in Patients With Type 2 Diabetes Across Countries in the Middle East and Africa (PACT-MEA)

Diabetes Mellitus, Type 2

Bahrain, Egypt, Jordan, Kuwait, Qatar, South Africa, United Arab Emirates
Medtronic Endovascular

Completed

The Complete® SE SFA Study for the Treatment of SFA/PPA Lesions

Peripheral Vascular Disease

United States
University of KwaZulu
AIDS Malignancy Consortium; National Research Foundation, Singapore; AIDS Care... and other collaborators

Completed

HIV/AIDS Kaposis Sarcoma: Comparison of Response to HAART vs HAART Plus CXT (KAART)

HIV | Kaposi's Sarcoma | AIDS | Human Herpesvirus 8

South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
Ripple Therapeutics Pty Ltd
Novotech (Australia) Pty Limited

Active, not recruiting

Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - A Sustained, Low Dose Dexamethasone Therapy

Diabetic Macular Oedema | Retinal Vein Occlusion With Macular Oedema

Australia, New Zealand, Hong Kong, Canada
University of Cape Town

Completed

Prevalence of Hypertensive Disease in Patients Presenting for Elective Surgery in the Western Cape, South Africa (HASS)

Hypertensive Episode

South Africa
Patrick Kelly

Completed

Effects of Paclitaxel on Intimal Hyperplasia (Pac1)

Peripheral Vascular Disease

United States
Flinders University
The Queen Elizabeth Hospital; Flinders Medical Centre; Royal Adelaide Hospital

Completed

Effect of Exercise Training on Protein Expression in Skeletal Muscle Tissue After Exercise in Peripheral Arterial Disease

Peripheral Arterial Disease

Australia
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
Alucent Biomedical

Active, not recruiting

Feasibility Study of the Vessel Restoration System (VRS) for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery (SFA) and/or Popliteal Artery (PA) After Sub-optimal Percutaneous Transluminal Angioplasty (PTA) or Atherectomy: REACTIVATE I (REACTIVATE I)

PAD - Peripheral Arterial Disease

Australia
The University of New South Wales

Terminated

The ABSORB Bioresorbable Scaffold Below the Knee (BTK) Study

Ischemia | Arterial Occlusive Diseases | Peripheral Arterial Disease (PTA

New Zealand, Australia, Netherlands
GlaxoSmithKline

Completed

SB-659032 Platelet Aggregation Study

Atherosclerosis

Australia
University of KwaZulu
King's College London; Department for International Development, United Kingdom and other collaborators

Completed

Strengthening Mental Health Care in Chronic Care Patients With Hypertension. A Cluster Randomised Control Trial

Depression | Hypertension

South Africa
Dakota Vascular

Completed

Comparing BlueDop Vascular Expert to Ankle-Brachial Index in the Identification of Peripheral Vascular Disease in All-comers and Diabetic Patients

Diabetes Mellitus | Peripheral Arterial Disease

United States
Abbott Medical Devices

Completed

XIENCE V: SPIRIT WOMEN

Myocardial Ischemia | Coronary Artery Disease | Coronary Arteriosclerosis | Stent Thrombosis | Vascular Disease | Coronary Artery Stenosis | Total Coronary Occlusion | Coronary Artery Restenosis

France, Italy, Norway, China, Spain, Germany, United Kingdom, Switzerland, Israel, Denmark, Belgium, Austria, Poland, Australia, Portugal, Argentina, Brazil, Hungary, Latvia, Netherlands, India, Greece, Malaysia, Russian Federation, South... and more
GlaxoSmithKline

Completed

Effect Of Rilapladib (SB-659032) On Platelet Aggregation

Atherosclerosis | Healthy Subjects

Australia
W.L.Gore & Associates

Terminated

GORE PROPATEN Vascular Graft vs. Disadvantaged Autologous Vein Graft (PRODIGY)

Peripheral Arterial Occlusive Disease

United States
Symic Vascular
Symic Biomedical, Inc.

Unknown

Angioplasty + SBCV vs. Angioplasty Alone for Femoropopliteal Artery Stenosis (SHIELD)

Peripheral Arterial Disease

Australia, New Zealand
Harvest Technologies

Completed

Study of Autologous Bone Marrow Concentrate for the Treatment of Critical Limb Ischemia (CLI)

Ischemia

United States

Clinical Trials on Vascular Disease Occlusive in South Africa

Sponsors and Collaborators

Medical Conditions

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CROs in Pakistan

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