Clinical Trials on Warm Antibody Hemolytic Anemia

Total 1648 results

ADDMEDICA SASA

Completed

Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)

Sickle Cell Disease | Renal Function Disorder

France
Billy Sin

Terminated

Ketamine Infusion for Acute Sickle Cell Crisis in the Emergency Department (KISS)

Pain | Sickle Cell Disorder

United States
Assistance Publique - Hôpitaux de Paris

Completed

Future of Spermatogenesis in Men With Sickle Cell Disease Medically Treated (HYDREP)

Drepanocytic Men Treated by Hydroxyurea for the First Time

France
UCSF Benioff Children's Hospital Oakland

Completed

Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease

Sickle Cell Anemia | Bone Avascular Necrosis

United States
Kanglin Biotechnology (Hangzhou) Co., Ltd.

Not yet recruiting

A Phase I/II Clinical Study of the KL003 Cell Injection in β-Thalassemia Major Participants

Transfusion-dependent Beta-Thalassemia

China
Institute of Hematology & Blood Diseases Hospital...
Kanglin Biotech

Recruiting

Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients

Transfusion-dependent Beta-Thalassemia

China
BGI-research
Shenzhen Children's Hospital

Not yet recruiting

Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients

β-Thalassemia Major

China
Ionis Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)

Beta Thalassemia Intermedia

Australia, Thailand, Greece, Lebanon, Turkey
Imperial College London

Completed

T2* in Transfusion Dependant Anemia, MI, LVF, Normal Patients

Thalassemia
EdiGene (GuangZhou) Inc.
PLA 923 Hospital

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects With Transfusion Dependent β-Thalassaemia.

Transfusion Dependent Beta-Thalassaemia

China
Celgene
Acceleron Pharma Inc. (a wholly owned subsidiary of Merck Sharp and Dohme...

Completed

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia (BELIEVE)

Beta-Thalassemia | Erythrocyte Transfusion

United States, Israel, Australia, Turkey, Taiwan, Malaysia, United Kingdom, Canada, Thailand, France, Lebanon, Italy, Bulgaria, Greece, Tunisia
UCSF Benioff Children's Hospital Oakland

Completed

Zinc and Diabetes in Patients With Thalassemia: a Pilot Study

Thalassemia

United States
Aghia Sophia Children's Hospital of Athens

Unknown

B Memory Cell Response to Vaccination With the 13-valent Pneumococcal Conjugate Vaccine in Asplenic Individuals

Asplenia | β-thalassemia Major

Greece
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) (EPiTOMISE)

Malaria,Falciparum

Kenya
HaEmek Medical Center, Israel

Completed

Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia

Sickle Cell Disease | Thalassemia

Israel
HaEmek Medical Center, Israel

Completed

Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia

Sickle Cell Anemia | Sickle Cell Thalassemia

Israel
Hillel Yaffe Medical Center

Unknown

Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia

Sickle Cell Anemia | Beta-Thalassemia | Microalbuminuria
Assiut University

Not yet recruiting

Detection of Krupple Like Factor -1(KLF1/ EKLF) DNA Mutations in Beta Thalassemia Patients

EKLF Mutations in Beta Thalassemia Patients
Sanofi

Recruiting

Cold Agglutinin Disease Real World Evidence Registry (CADENCE)

Cold Agglutinin Disease (CAD) | Cold Agglutinin Syndrome (CAS)

United States, Austria, France, Italy, Germany, Japan, Spain, United Kingdom
Cairo University

Recruiting

Correlation Between Pulmonary Functions and Physical Fitness in Children With β-thalassemia

Pulmonary Function | Physical Fitness | β-Thalassemia

Egypt
Swiss Federal Institute of Technology
Mahidol University

Not yet recruiting

Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults With Thalassemia

Iron Overload | Thalassemia

Thailand
Gliknik Inc.

Recruiting

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease

First in Man Study to Evaluate Initial Safety

United Kingdom
Celgene

Terminated

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Beta Thalassemia Intermedia | Beta Thalassemia Major

France, United Kingdom, Italy, Greece
HaEmek Medical Center, Israel

Completed

Renal Function Among Thalassemia Patients Treated by a Oral Chelator Deferasirox

Iron Overload | Thalassemia

Israel
Oman Medical Speciality Board
Armed Forces Hospital, Oman

Not yet recruiting

Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department (PASC)

Sickle-Cell Disease With Crisis
Washington University School of Medicine
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Metabolic and Hemodynamic Reserve in Pediatric SCA

Brain Diseases | Sickle Cell Disease | Anemia, Sickle Cell | Child, Only

United States
University of Illinois at Chicago

Recruiting

Glucose Metabolism in Sickle Cell Disease

Diabetes Mellitus | Sickle Cell Disease

United States
University of Illinois at Chicago

Recruiting

Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)

Sickle Cell Disease

United States
Sangamo Therapeutics

Enrolling by invitation

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Blood and Lymphatic Diseases

United States
Johns Hopkins University
Medical University of South Carolina; Children's Hospital of Philadelphia; Washington... and other collaborators

Completed

Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease (HUPrevent)

Stroke | Sickle Cell Disease

United States
Argo Sante
Filière de santé maladies rares MCGRE; Fédération des malades drépanocytaires... and other collaborators

Completed

Evaluation of Impact of Disease on Quality of Life, Education and Socio-professional Integration of Adults and Parents of Children Living With Sickle- Cell Disease in France (DREPAtient)

Sickle-cell Disease (SCD)

France
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Unknown

TAPS2 Transfusion Antenatally in Pregnant Women With SCD (TAPS2)

Pregnancy, High Risk | Sickle Cell Disease | Blood Transfusion Complication

United Kingdom
Duke University

Completed

Stigma, Self-management, & Quality of Life in SCD (SSQ)

Quality of Life | Sickle Cell Disease | Stigma, Social | Disease Self-Management

United States, Jamaica
AstraZeneca

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease (HESTIA 1)

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

United States, Canada, United Kingdom, South Africa, Lebanon, Kenya
Novartis Pharmaceuticals

Completed

Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions

Anemia, Sickle Cell

United States
Emory University
Patient-Centered Outcomes Research Institute

Completed

Decision Aid for Therapeutic Options In Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Hemoglobin SC | Hemoglobin SS | Hemoglobin Beta Thalassemia

United States
Sangart

Completed

Safety Study of MP4CO in Adult Sickle Cell Patients

Sickle Cell Disease | Anemia, Sickle Cell | Sickle Cell Anemia | Hemoglobin SC Disease | Sickle Cell Disorders | Sickle Cell Hemoglobin C Disease

United Kingdom, France, Jamaica, Lebanon
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Pilot Study (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United Kingdom, United States, Germany
Paul Szabolcs

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sickle Cell Anemia | Diamond-blackfan Anemia | Beta-thalassemia Major

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing Factors

Acute Leukemia | Thalassemia Major

China
Hangzhou Zede Pharma-Tech Co., Ltd.

Recruiting

Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients

Iron Overload | Thalassemia

China
Hangzhou Zede Pharma-Tech Co., Ltd.

Completed

Long-term Clinical Study of CN128 in Thalassemia Patients

Iron Overload | Thalassemia

China
Memorial Sloan Kettering Cancer Center

Active, not recruiting

ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene

Confirmed Diagnosis of ß-thalassemia Major

United States
Elliott Vichinsky

Completed

Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload

Iron Overload | Thalassemia

United States
Assiut University

Unknown

Sexual Maturation in β-Thalassemia Major Patients in Assiut University Hospital

β-Thalassemia Major Patients Receiving Chelation Therapy
Tanta University

Unknown

Benefits of Nigella Sativa in Children With Beta Thalassemia Major (Nigella)

Nigella Sativa With Beta Thalassemia Major

Egypt
The University of Hong Kong

Completed

Use of 3D/4D Ultrasound in the Evaluation of Fetal Anomalies

Homozygous αº-thalassemia | Hb Bart's Disease

China
Azienda Ospedaliera V. Cervello

Completed

Efficacy Study of the Use of Sequential DFP-DFO Versus DFP (SEQDFPDFO)

Beta-Thalassemia | Thalassemia Major

Italy
Vanderbilt University Medical Center
Aminu Kano Teaching Hospital; Murtala Muhammed Specialist Hospital

Not yet recruiting

Prevention of Malnutrition in Children With Sickle Cell Disease (PMC-SCD)

Malnutrition | Sickle Cell Disease
Hospices Civils de Lyon

Completed

Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France (EVADDREP)

Vitamin D Deficiency | Sickle Cell Disease

France

Clinical Trials on Warm Antibody Hemolytic Anemia

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