Clinical Trials on Wet Macular Degeneration

Total 54248 results

Adverum Biotechnologies, Inc.
Parexel

Active, not recruiting

Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA]

Neovascular Age-related Macular Degeneration

United States, France, United Kingdom
Mid-Atlantic Retina Consultations, Inc.
West Virginia University

Unknown

Supplemental Adjuvants for Intracellular Nutrition and Treatment (SAINTS)

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Bayer
Regeneron Pharmaceuticals

Terminated

A Study to Learn How Well Aflibercept Injected Into the Eye Works and How Safe it is When Given in Customized Treatment Intervals in Patients With an Eye Disease Called Neovascular Age-related Macular Degeneration After Start of Treatment (XPAND)

Neovascular (Wet) Age-related Macular Degeneration

Canada, United Kingdom
Ashvattha Therapeutics, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Healthy Participants

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

Australia
David M. Brown, M.D.
Genentech, Inc.

Terminated

A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial) (SAVE)

Macular Degeneration | Age Related Macular Degeneration | Wet Age-Related Macular Degeneration | Choroidal Neovascular Membrane | Subfoveal Neovascular Age-Related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

Observation of Treatment Patterns With Lucentis® in Real-life Conditions in All Approved Indications (PACIFIC)

Neovascular (Wet) Age-related Macular Degeneration

Germany, Switzerland, Netherlands
Bayer
Regeneron Pharmaceuticals

Completed

Caregiver Burden of Wet Age-related Macular Degeneration (wAMD) in Japan

Wet Macular Degeneration

Japan
Hoffmann-La Roche

Completed

A Study in Patients With Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema to Evaluate the Safety of the Faricimab Prefilled Syringe

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Daiichi Sankyo, Inc.

Completed

Study of DS-7080a for the Treatment of Macular Degeneration

Diabetic Macular Edema | Neovascular Age-Related Macular Degeneration

United States
Lpath, Inc.
Pfizer

Terminated

iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects With Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV) (PED)

Pigment Epithelial Detachment

United States
University of Helsinki

Completed

Connection Between Periodontitis and Exudative Age-related Macular Degeneration (FLAREPARO)

Periodontitis

Finland
Adverum Biotechnologies, Inc.

Completed

ADVM-022 Intravitreal Gene Therapy for Wet AMD (OPTIC)

Neovascular Age-related Macular Degeneration | Wet Age-related Macular Degeneration

United States
Adverum Biotechnologies, Inc.

Active, not recruiting

Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]

Neovascular Age-related Macular Degeneration | Wet Age-related Macular Degeneration

United States
King's College Hospital NHS Trust

Completed

Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD (TAPAS)

Exudative Macular Degeneration | Retinal Hemorrhage

United Kingdom
Bayer
Regeneron Pharmaceuticals

Active, not recruiting

Study of the Effects of High Dose Aflibercept Injected Into the Eye of Patients With an Age-related Disorder That Causes Loss of Vision Due to Growth of Abnormal Blood Vessels at the Back of the Eye (PULSAR)

Neovascular Age-Related Macular Degeneration

United States, Spain, Korea, Republic of, Czechia, Japan, Singapore, China, Serbia, Lithuania, Taiwan, Australia, Estonia, Austria, Israel, France, Italy, Switzerland, Slovakia, Ukraine, Bulgaria, Portugal, Latvia, Canada, Hungary, Arge... and more
AiViva BioPharma, Inc.

Recruiting

Effect of AIV007 by Periocular Administration in Subjects With nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Sohag University

Not yet recruiting

Optical Coherence Tomography Angiography Criteria Of The Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia (Comparative Study).

Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia
Johns Hopkins University

Terminated

Anti-VEGF Therapy for Subfoveal Hemorrhage in Patients With Neovascular Age-Related Macular Degeneration

Wet Macular Degeneration | Neovascular Age-related Macular Degeneration | Submacular Hemorrhage

United States
Novartis Pharmaceuticals

Completed

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting (LUMINOUS)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age Related Macular Degeneration | Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion

Spain, China, Colombia, Korea, Republic of, Belgium, Greece, Japan, Russian Federation, Turkey, United Kingdom, Egypt, Germany, Australia, Canada, France, Austria, Hong Kong, Hungary, Israel, Netherlands, Peru, Singapore, Slovakia, Sl... and more
Samsung Bioepis Co., Ltd.

Completed

A Study to Evaluate the Usability of the SB11 PFS in Subjects With Wet AMD or Macular Oedema Secondary to RVO

Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

Poland
Regeneron Pharmaceuticals

Not yet recruiting

Study to Evaluate an 8 mg Aflibercept (EYLEA®) Prefilled Syringe (PFS)

Diabetic Macular Edema (DME) | Neovascular Age-Related Macular Degeneration (nAMD)
AbbVie

Recruiting

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD (ASCENT)

CNV | AMD | nAMD | Wet Age-related Macular Degeneration | wAMD | WetAMD

United States, Puerto Rico, Canada
Kodiak Sciences Inc

Completed

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) (DAYLIGHT)

Wet Age-related Macular Degeneration

United States, Puerto Rico
EyeBiotech Ltd.

Recruiting

A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD) (AMARONE)

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (NVAMD)

United States, Argentina, Puerto Rico, United Kingdom
University of California, Los Angeles
ThromboGenics

Unknown

Study of Intravitreal Microplasmin in Relieving Vitreo-Macular Adhesion in Neovascular Age-related Macular Degeneration (AMD)

Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

Study to Evaluate the Safety and Effectiveness of Intravitreal Injections (IVI) of Brolucizumab in Patients With Neovascular Age-related Macular Degeneration (nAMD)

Neovascular Age-related Macular Degeneration (nAMD)

India
Kodiak Sciences Inc

Terminated

Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age-related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients

Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

United States, Puerto Rico
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, United Kingdom, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan
Gemini Therapeutics, Inc.

Terminated

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration

Macular Degeneration | Retinal Degeneration | Neovascular Age-related Macular Degeneration | Retinal Disease

United States
Aerie Pharmaceuticals

Completed

A Study Assessing AR-13503 Implant in Subjects With nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Wills Eye
Mid Atlantic Retina; J. Arch McNamara Research Fund

Completed

Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.

Age-related Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion | Wet Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMD

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Retinal Degeneration | Retinal Diseases | Wet Macular Degeneration

United States, Puerto Rico
ThromboGenics

Completed

Safety and Efficacy Study of Intravitreal Ocriplasmin in Subjects With AMD With Focal Vitreomacular Adhesion (MIVI-5)

Exudative Age-Related Macular Degeneration | Focal Vitreomacular Adhesion

United States, United Kingdom, Germany, France, Belgium, Italy
Pacific Eye Associates
Genentech, Inc.

Completed

Lucentis for Age-related Macular Degeneration Pigment Epithelial Detachments (DETAIL)

Age-related Macular Degeneration | Wet Macular Degeneration | Pigment Epithelial Detachment | Neovascular Macular Degeneration

United States
Guy's and St Thomas' NHS Foundation Trust
Macusoft

Not yet recruiting

Artificial Intelligence Diagnostic Aid (AID)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Macular Degeneration

United Kingdom
The Retina Center of St. Louis County, PC

Completed

Triple Combination Therapy of Choroidal Neovascularization in AMD, a Cost Effect and Efficient Therapeutic Treatment

Exudative Macular Degeneration

United States
Unity Biotechnology, Inc.

Completed

Safety and Tolerability Study of UBX1325 in Patients With Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Outlook Therapeutics, Inc.

Completed

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Age-related Macular Degeneration | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema

Diabetic Macular Edema | Macular Edema | Neovascular Age-related Macular Degeneration | Retinal Vein Occlusions

Puerto Rico, United States
Chengdu Kanghong Biotech Co., Ltd.
University of Wisconsin, Madison; Air Force Military Medical University, China

Completed

A Study Assessing the Safety and Efficacy of Multiple Intravitreal KH902 in Patients With CNV Due to AMD (HOPE)

Neovascular Age-related Macular Degeneration

China
Alcon Research

Completed

Efficacy and Safety of RTH258 Versus Aflibercept - Study 2 (HARRIER)

Choroidal Neovascularization | Neovascular Age-Related Macular Degeneration
Alcon Research

Completed

Efficacy and Safety of RTH258 Versus Aflibercept - Study 1 (HAWK)

Choroidal Neovascularization | Neovascular Age-Related Macular Degeneration

United States
Outlook Therapeutics, Inc.

Completed

A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Age-related Macular Degeneration | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration

Australia
Novartis

Completed

Safety and Efficacy of Oral PTK787 in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration (AMD) (ADVANCE)

Wet Age-Related Macular Degeneration

Australia, United States
AbbVie
AbbVie

Recruiting

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD) (AAVIATE)

Neovascular Age-Related Macular Degeneration (nAMD)

United States
Institut de la Macula y la Retina
Igen BioLab SLU

Recruiting

Study to Evaluate the Response to Supplementation With Postbiotics in Patients With Macular Degeneration. (REVERS)

AMD | Drusen Stage Macular Degeneration | Soft Drusen | Reticular Pseudodrusen | Drusen (Degenerative) of Macula, Bilateral

Spain
Anne Fung MD
Genentech, Inc.

Terminated

HiPED - High Dose Lucentis for Persistent Pigment Epithelial Detachments in Age-related Macular Degeneration (HiPED)

Macular Degeneration | Wet Macular Degeneration | Retinal Pigment Epithelial Detachment

United States
Iconic Therapeutics, Inc.

Terminated

Open-Label Study of Intravitreal ICON-1 in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD) (DECO)

Choroidal Neovascularization | Wet Macular Degeneration

United States
Shanghai BDgene Co., Ltd.
Eye & ENT Hospital of Fudan University

Recruiting

VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization Diseases

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

China

Clinical Trials on Wet Macular Degeneration

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