Clinical Trials on beta-manosidosis

Total 446 results

Bioray Laboratories
Xiangya Hospital of Central South University; The 923rd Hospital of Joint Logistics...

Recruiting

Long-term Follow-up Study of BHC001 for TDT

Thalassemia, Beta

China
Nanfang Hospital of Southern Medical University
Shenzhen Second People's Hospital; Shenzhen Children's Hospital; ZhuHai Hospital and other collaborators

Recruiting

Association of Hb F Level With Clinical Severity of Beta Thalassemia

Beta Thalassemia

China
Nanfang Hospital of Southern Medical University
303rd Hospital of the People's Liberation Army; Liuzhou Municipal Maternity... and other collaborators

Recruiting

Genetic Variants Affecting the Clinical Severity of Beta Thalassemia

Beta Thalassemia

China
HaEmek Medical Center, Israel

Completed

Demographic, Clinical, Laboratory and Genetical Characteristics of Patients With Beta Thalassemia Intermedia

Thalassemia

Israel
Deborah Rund

Completed

Genetic Factors Affecting the Severity of Beta Thalassemia

Beta Thalassemia

Israel
Mahidol University
ChaingMai University

Completed

Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients

Thalassemia

Thailand
National Institute of Diabetes and Digestive and...

Completed

5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia

Beta Thalassemia

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Malaria | Sickle Cell Disease | Alpha and Beta Thalassemia | Human Physiology

United States
Nova Laboratories Limited

Completed

Pharmacokinetics of Oral Hydroxyurea Solution (HUPK)

Sickle Cell Disease | Sickle Cell Hemoglobin C | Sickle Cell-beta-thalassemia | Sickle-Cell; Hemoglobin Disease, Thalassemia

United Kingdom, Jamaica
Tanta University

Completed

Effect of Spirulina on Serum Hyaluronic Acid in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
404 General Military Hospital, Larissa

Unknown

B-Thalasaemia Trait and Its Possible Cardioprotective Role

Coronary Artery Disease | Beta-Thalassemia Trait

Greece
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis

Hematologic Diseases | Iron Overload | Hemoglobinopathies | Thalassemia | Beta-Thalassemia | Hemochromatosis | Anemia (Iron-Loading)
CENTOGENE GmbH Rostock

Terminated

European Alpha-Mannosidosis Participant (EUMAP)

Deafness | Immunodeficiency | Mental Retardation | Gingival Hypertrophy | Skeletal Abnormalities | Facial Dysmorphism

Germany, Switzerland
University Hospital, Basel, Switzerland

Recruiting

Clinical Comparison of Treatment Strategies in AmpC Beta-lactamase Producing Enterobacterales in a Swiss Tertiary Care Hospital (AmpCstratBasel)

Infection With AmpC Beta-lactamase Producing Enterobacterales

Switzerland
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
Institute of Hematology & Blood Diseases Hospital...
Shanghai Vitalgen BioPharma Co., Ltd.

Recruiting

Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells

Thalassemia Major | Thalassemia, Beta

China
Children's Hospital Karachi

Completed

Thalidomide and Hydroxyurea Combination in β-Thalassemia Patients

Thalassemia, Beta

Pakistan
Assiut University

Unknown

Detection Of β-thalassemia Carriers In Assiut

Beta-Thalassemia
Shiraz University of Medical Sciences

Completed

Immunomodulatory Effects of Silymarin in Patients With Beta-Thalassemia Major

Immune Abnormalities

Iran, Islamic Republic of
Children's Hospital Karachi

Completed

Clinical Experience of Thalidomide in Thalassemic Patients

Thalassemia, Beta

Pakistan
Tanta University

Completed

Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia Major

Beta Thalassemia

Egypt
Tanta University

Completed

Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Novartis Pharmaceuticals

Completed

Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration) (ESCALATOR)

Iron Overload | Hemosiderosis | Beta-thalassemia Major | Rare Anemia

Egypt, Oman, Saudi Arabia, Syrian Arab Republic, Lebanon
National Institute of Diabetes and Digestive and...

Completed

Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)

Beta Thalassemia | Hemoglobinopathy

United States
Ain Shams University

Recruiting

PK of SOF/LED in HCV - Infected Adolescents With Haematological Disorders

HCV Infection | Beta Thalassemia Major

Egypt
University Hospital, Montpellier
Institut de Génomique Fonctionnelle (IGF) de Montpellier

Not yet recruiting

Plasma Beta-endorphin Levels and Suicidal Behavior (BEST)

Depression | Suicide | Beta Endorphin

France
Kaleido Biosciences

Terminated

VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms (VITORA)

Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects

United States
University of Pennsylvania
Washington University School of Medicine

Completed

Escitalopram Effects on CSF Amyloid Beta

Amyloid Beta Protein

United States
Meir Medical Center

Completed

Extended Open Challenge in Patients With a History of Drug Eruption Following Beta-lactam Treatment

Beta-lactam Allergy

Israel
Kanglin Biotechnology (Hangzhou) Co., Ltd.

Not yet recruiting

A Phase I/II Clinical Study of the KL003 Cell Injection in β-Thalassemia Major Participants

Transfusion-dependent Beta-Thalassemia

China
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Treatment of Orthostatic Hypotension

Autonomic Nervous System Diseases | Orthostatic Hypotension | Orthostatic Intolerance | Dopamine Beta-Hydroxylase Deficiency

United States
Bioray Laboratories
Xiangya Hospital of Central South University; First Affiliated Hospital of... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

China
Imara, Inc.

Terminated

A Study of IMR-687 in Subjects With Beta Thalassemia

β Thalassemia

Israel, France, Malaysia, Turkey, Denmark, Georgia, Greece, Italy, Lebanon, Morocco, Netherlands, Tunisia, United Kingdom
Acceleron Pharma Inc. (a wholly owned subsidiary...

Completed

Study to Evaluate the Effects of ACE-536 in Patients With Beta-thalassemia

B-Thalassemia

Italy, Greece
CorrectSequence Therapeutics Co., Ltd

Recruiting

A Safety and Efficacy Study Evaluating CS-101 in Subjects With β-Thalassemia Major

Beta-Thalassemia Major

China
Ain Shams University

Completed

Congenital Heart Surgery in Pediatric Patients With Beta-Thalassemia Major

Hemolysis
First Affiliated Hospital of Guangxi Medical University

Unknown

Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism

Beta Thalassemia Major

China
Antonio Martín Duce

Completed

Double-blind, Randomized Controlled Study to Assess the Analgesic Effect of 2 g of Magnesium Dipyrone (Metamizol) and Changes in Plasma Beta-endorphin Immunoreactivity Values in Patients Undergoing Elective Inguinal Herniorrhaphy Under Epidural Anesthesia.

Pain | Hernia Surgery | Beta-endorphin | Dipyrone

Spain
Imperial College London

Completed

Beta-lactam Pharmacokinetics in Secondary Care

Pharmacokinetics | Penicillin Allergy | Beta Lactam Adverse Reaction

United Kingdom
Celgene

Recruiting

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Beta-thalassemia | Myelodysplastic Syndromes (MDS) | Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis

United States, Japan, United Kingdom, Turkey, Greece, France, Australia, Belgium, Bulgaria, Canada, Germany, Israel, Italy, Malaysia, Spain, Sweden, Taiwan, Thailand, Tunisia, Lebanon, China, Netherlands
Novartis Pharmaceuticals

Completed

Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload

Myelodysplastic Syndromes | Beta-Thalassemia

Hungary
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Sickle Cell Disease | Thalassemia | Thalassemia, Beta

United States
Vanderbilt University Medical Center

Completed

The Pathophysiology of Orthostatic Hypotension

Autonomic Nervous System Diseases | Orthostatic Hypotension | Orthostatic Intolerance | Dopamine Beta-Hydroxylase Deficiency

United States
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Sickle Cell Disease | Beta-Thalassemia Major

France
Tanta University

Completed

Hyalornic Acid Level in β-Thalassemic Children Treated for Hepatitis C Virus

Hepatitis C | Beta-Thalassemia

Egypt
Tanta University

Completed

Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
Tanta University

Unknown

Study of The Therapeutic Benefits of Al-hijamah in Children With Beta Thalassemia Major (Al-hijamah)

AL-Hijama in Thalassmia Major

Egypt
Chulalongkorn University

Completed

The Diagnosis of Beta-lactam Hypersensitivity in Thailand

Penicillin Allergy | Beta Lactam Adverse Reaction | Aminopenicillin Allergy

Thailand
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Sickle Cell Anemia | Beta Thalassemia

United States

Clinical Trials on beta-manosidosis

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