Clinical Trials on the Mitochondrial Pathway in South Africa
Total 458 results
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University of Witwatersrand, South AfricaTerminatedMetabolic Complications | Mitochondrial ToxicitySouth Africa
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Swiss Federal Institute of TechnologyNorth-West University, South AfricaCompletedFocus: Establish the Iodine Requirement During InfancySwitzerland, South Africa
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D3 Bio (Wuxi) Co., LtdRecruitingAdvanced Solid Tumors With MAPK Pathway MutationsAustralia, China, United States
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Reneo Pharma LtdTerminatedPrimary Mitochondrial MyopathySpain, Australia, Belgium, Denmark, Canada, United Kingdom, France, Germany, Hungary, Italy, Netherlands, New Zealand
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Stealth BioTherapeutics Inc.Active, not recruitingMitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism DefectSpain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
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University of Cape TownUnknownBiliary Stricture | Cancer of the Pancreas | Bile Duct Obstruction, Extrahepatic | Cancer of the Bile DuctSouth Africa
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Reneo Pharma LtdCompletedPrimary Mitochondrial MyopathyUnited States, Spain, Australia, France, United Kingdom, New Zealand, Denmark, Norway, Czechia, Belgium, Canada, Germany, Hungary, Italy, Netherlands
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Cycle Pharmaceuticals Ltd.ParexelCompletedAcute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditionsSouth Africa
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Harriet Shezi Children's ClinicUnknownChildren With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of EnrollmentSouth Africa
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DePuy InternationalTerminatedOsteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral FracturesSouth Africa
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Stealth BioTherapeutics Inc.CompletedPrimary Mitochondrial DiseaseUnited States, Spain, Germany, Australia, Canada, Denmark, Hungary, Italy, United Kingdom
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Arthrex, Inc.RecruitingHyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditionsGermany, United States, South Africa
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Novartis PharmaceuticalsCompletedPaget's Disease of the BoneSpain, Canada, New Zealand, Belgium, South Africa, United Kingdom
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Novartis PharmaceuticalsCompletedPI3K Pathway Activated TumorsUnited States
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PTC TherapeuticsEnrolling by invitationInherited Mitochondrial DiseaseUnited States, France, Spain, United Kingdom, Italy, Poland, Japan
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationAustralia
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Antiva BiosciencesCompletedCervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical NeoplasmSouth Africa
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PTC TherapeuticsNo longer available
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International Atomic Energy AgencyUnknownCancer of the CervixIndia, South Africa, Tanzania, Uganda, Zimbabwe
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Rhythm Pharmaceuticals, Inc.Active, not recruitingObesity Associated With Defects in Leptin-melanocortin PathwayUnited States, Netherlands, Canada, Germany, United Kingdom, France, Greece, Spain
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AIDS Malignancy ConsortiumNational Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaboratorsActive, not recruitingHIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial NeoplasiaUganda, Kenya, Zimbabwe, South Africa, Malawi
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University of the West of ScotlandSwansea UniversityCompletedTo Assess the Impact of the HIT Intervention on Physiological Responses | To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours | To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old YouthUnited Kingdom
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AO Clinical Investigation and Publishing DocumentationDePuy SynthesActive, not recruitingTibial Fracture | Fracture of the Tibia Type AO/OTA 42United States, Hong Kong, Korea, Republic of, Switzerland, Singapore, Germany, South Africa, United Kingdom, Belgium
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International Atomic Energy AgencyTata Memorial Centre; University of Maryland, College Park; Centro de Lucha contra... and other collaboratorsUnknownSquamous Cell Carcinoma of the Head and NeckIndia, Argentina, Cuba, Indonesia, Pakistan, Philippines, South Africa, Thailand, Uruguay
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University of MiamiNational Institute of Neurological Disorders and Stroke (NINDS); National Institutes...RecruitingAmyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Frontotemporal Dementia | Progressive Muscular Atrophy | Hereditary Spastic ParaplegiaUnited States, South Africa
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Lumen BiomedicalCompleted
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Novartis PharmaceuticalsCompletedTumors With CDK4/6 Pathway ActivationUnited States
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AO Clinical Investigation and Publishing DocumentationAOCMFCompletedBilateral Condylar Fracture of the MandibleUnited States, Taiwan, Switzerland, South Africa, Finland, Slovenia, Pakistan, Spain, Germany, Malaysia, Mexico, Netherlands, Ukraine, Uruguay
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City of Hope Medical CenterNational Cancer Institute (NCI)CompletedAdenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Adenocarcinoma of the Esophagus | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma of the Stomach | Mixed Adenocarcinoma...United States
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Sheffield Hallam UniversityUnknownModulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT GeneUnited Kingdom
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Novartis PharmaceuticalsCompletedTumor Pathway Activations Inhibited by DovitinibUnited States
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GlaxoSmithKlineCompleted
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University of WashingtonNational Cancer Institute (NCI)CompletedStage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Nasopharynx | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous... and other conditionsUnited States
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Bionomics LimitedCompleted
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Nutricia ResearchUnknownComplex Conditions, Including Impairment of the GI TractUnited Kingdom, United States, Germany
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Keythera Pharmaceuticals (Australia) Pty LtdRecruitingGastric Cancer | Colorectal Cancer | Lung Cancer | Bladder Cancer | Advanced Solid Tumor | Squamous Cell Carcinoma of the EsophagusAustralia
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Xgene Pharmaceutical GroupNovotech (Australia) Pty LimitedCompleted
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National Cancer Institute (NCI)CompletedNeurofibromatosis Type 1 | Recurrent Childhood Pilocytic Astrocytoma | Recurrent Childhood Visual Pathway GliomaUnited States, Canada, Australia, New Zealand
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Sheffield Teaching Hospitals NHS Foundation TrustCompleted
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Provectus Biopharmaceuticals, Inc.Active, not recruitingNeuroendocrine Tumors Metastatic to the LiverAustralia
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Western Sydney Local Health DistrictCompletedEndoscopic Mucosal Resection | Delayed Bleeding Post EMR | Large Laterally Spreading Lesion in the ColonAustralia
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Taiwan Liposome CompanyCompletedOSTEOARTHRITIS OF THE KNEETaiwan, United States
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AstraZenecaCompletedPainful Osteoarthritis of the KneeSpain, United Kingdom, South Africa, Poland, Estonia, Denmark, Germany
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GlaxoSmithKlineCompletedOsteoarthritisAustralia
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Murdoch Childrens Research InstituteActive, not recruiting
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InGeneron, Inc.Sanford HealthRecruitingOsteoarthritis of the WristUnited States
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Pacira Pharmaceuticals, IncCompletedOsteoarthritis of the KneeAustralia
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Boston Scientific CorporationCompletedAtherosclerotic Lesions in the Aortorenal OstiumUnited States
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GlaxoSmithKlineCompletedMultiple Sclerosis, Relapsing-RemittingAustralia
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Pfenex, IncCompleted