Search clinical trials for: (11C) flumazenil

Total 2232 results

Lexicon Pharmaceuticals

Completed

An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Males (LX1606-104)

Carcinoid Syndrome

United Kingdom
Sanofi

Completed

Study to Determine Absorption, Metabolism, and Excretion of [14C]-SAR439859, and to Assess Absolute Oral Bioavailability of Amcenestrant (SAR439859), in Healthy Post-menopausal Women

Breast Cancer | Healthy Volunteers

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Enpatoran Human Mass Balance and Absolute Bioavailability Study

Healthy

Netherlands
University of Minnesota

Completed

Pilot Study of Meat-Borne Carcinogens and Pancreatic Cancer

Pancreatic Cancer

United States
University of Lausanne

Completed

Fructose-induced Intestinal de Novo Lipogenesis (FIDNL)

Obesity

Switzerland
Hospices Civils de Lyon

Completed

[11C]Yohimbine PET Study of alpha2-AR ([11C]Yohimbine)

Healthy Controls

France
Protalix

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Gout

New Zealand
Chang Gung Memorial Hospital
National Science and Technology Council

Not yet recruiting

Hyperpolarized 13C MRI for Cancer Immunotherapy (DNPSPIO)

Cervical Cancer | Gynecologic Cancer | Ovarian Cancer | Endometrial Cancer

Taiwan
Takeda

Completed

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

Healthy Volunteers

United States
Theravance Biopharma

Completed

TD-1473 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects

Bowel Diseases, Inflammatory | Intestinal Disorders

United States
PegBio Co., Ltd.
Covance

Completed

Dose-finding of PB-119 Administered Subcutaneously Once Weekly Versus Placebo in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)

United States
University of Texas Southwestern Medical Center

Recruiting

UTSW HP [13-C] Pyruvate Injection in HCM (HPHCM)

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Dilated Cardiomyopathy | Cardiomyopathy, Hypertrophic | Heart Failure With Reduced Ejection Fraction | Cardiac Sarcoidosis | Heart Failure With Preserved Ejection Fraction

United States
Basilea Pharmaceutica

Completed

Mass Balance and Pharmacokinetics Study of Derazantinib in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Santen Inc.

Completed

A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT

Glaucoma and Ocular Hypertension

United States
Microbio Co Ltd

Unknown

A Trial to Evaluate Safety, Tolerability, PK and Antiviral Activity of MB-110 in Hepatitis C Virus Infected Patients

Chronic Hepatitis C

Taiwan
University of California, San Francisco
National Cancer Institute (NCI)

Completed

11C- and 18F-Choline PET/MR Imaging for Prostate Cancer

Prostate Cancer

United States
National Institute of Neurological Disorders and...

Recruiting

Clinical Laboratory Evaluation of Chronic Autonomic Failure

Parkinson's Disease | Multiple System Atrophy | Autonomic Failure

United States
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Recruiting

APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors

Solid Tumor | Neuroblastoma

China
Avobis Bio, LLC
Alimentiv Inc.

Recruiting

Seeded Cells on Matrix Plug Treating Crohn's Perianal Fistulas (STOMP-II)

Crohn's Disease | Perianal Fistula

United States
TenNor Therapeutics (Suzhou) Limited

Completed

Human Mass Balance and Biotransformation Study of [14C]TNP-2198

Helicobacter Pylori Infection

China
BeiGene

Completed

A Study to Investigate the Absorption, Metabolism and Excretion of [14C]-BGB-11417

Healthy Volunteers

United States
argenx

Withdrawn

A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP) (ADVANCE2)

Primary Immune Thrombocytopenia (ITP)
BioMed Valley Discoveries, Inc

Completed

Absorption, Metabolism and Excretion (AME) of Single Dose Radiolabeled BVD-523 in Volunteers

Healthy
InQpharm Group

Completed

Influence of IQPAS-119 on Post-Marathon Susceptibility to Infections and Others

Upper Respiratory Tract Symptoms

Germany
Boehringer Ingelheim

Completed

Excretion Balance of 14c-radiolabeled BIRB 796 BS in Normal Male Subjects

Healthy
Astellas Pharma Inc

Completed

A Study to Assess the Systemic Disposition of ASP1585 After Administration of 14C-labeled Drug

Healthy | Pharmacokinetics of ASP1585

United States
Biomedical Radiation Sciences
Swedish Cancer Society

Completed

Exploratory Study of Breast Cancer With ABY025 (ABY0125)

Breast Cancer

Sweden
Tego Science, Inc.

Recruiting

A Phase 2b/3 Study of TPX-115 on Partial-thickness Rotator Cuff Tear

Partial Thickness Rotator Cuff Tear

Korea, Republic of
argenx

Completed

A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP). (ADVANCE)

Primary Immune Thrombocytopenia

United States, Austria, Belgium, Bulgaria, Czechia, France, Georgia, Germany, Hungary, Italy, Japan, Netherlands, Poland, Russian Federation, Spain, Turkey, Ukraine, United Kingdom
Tego Science, Inc.

Completed

A Phase I/III Clinical Study of TPX-114 for the Treatment of Full-Thickness Rotator Cuff Tear

Rotator Cuff Injuries

Korea, Republic of
Oscotec Inc.

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-SKI-O-703 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
Gilead Sciences

Completed

Phase I/II Study of Different Doses and Dose Schedules of Milatuzumab (hLL1) in CLL

Chronic Lymphocytic Lymphoma

United States
Betta Pharmaceuticals Co., Ltd.

Active, not recruiting

The Absorption, Metabolism and Excretion of [14C]D-0316 in Human

Advanced or Metastatic Non-small Cell Lung

China
Jazz Pharmaceuticals

Completed

Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in Narcolepsy

Narcolepsy | Excessive Sleepiness

Netherlands
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-BIIL 284 BS in Healthy Volunteers

Healthy
Neurocrine Biosciences
Takeda

Completed

A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants

Healthy Volunteers

United States
Pfizer

Completed

Study to Characterize Absorption, Distribution, Metabolism and Excretion of 14C PF-06651600 and to Evaluate the Absolute Oral Bioavailability and Fraction Absorbed of PF-06651600. (B7981011)

Healthy Volunteers

Netherlands
Huashan Hospital

Recruiting

A Study to Evaluate the Human Biodistribution and Dosimetry of the Radionuclide Labeled ZT-111 in Patients With Metastatic Prostate Cancer

Prostate Specific Membrane Antigen Positive Metastatic Prostate Cancer

China
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Drug Levels, Physical and Chemical Changes, and Removal of BMS-986196 in Healthy Male Participants

Healthy Male Volunteers

United States
Takeda

Available

Expanded Access to TAK-113 for Adults With Metastatic Colorectal Cancer (mCRC)

Colorectal Cancer
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
Cytosite Biopharma Inc.
University of Alabama at Birmingham

Completed

Study to Evaluate the Safety and Dosimetry of [68Ga]-NOTA-hGZP (CSB-111) PET Imaging in Healthy Human Volunteers.

Healthy Volunteers

United States
Taiho Pharmaceutical Co., Ltd.

Completed

A Mass Balance Study of [14C] TAS-303 in Healthy Adult Male Subjects

Healthy Male Subjects

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of [14C] TAS-205 in Healthy Volunteers

Healthy Male Subjects

Japan
Dana-Farber Cancer Institute

Completed

Effect of Eltrombopag Plus G-CSF on Human CD34+ Cell Mobilization in Multiple Myeloma Patients Undergoing ASCT

Multiple Myeloma

United States
Akros Pharma Inc.

Completed

Mass Balance Study of JTZ-951 in Subjects With End-stage Renal Disease on Hemodialysis

Anemia of Chronic Kidney Disease

United States
Abbott

Terminated

A Pharmacokinetic Study to Access How the Body Absorbs and Removes Linifanib in Male Patients With Advanced Solid Tumors.

Advanced Solid Tumors

United States
RANI Therapeutics

Completed

Study Evaluating PK of Ustekinumab Administered Orally Via RaniPill™ Capsule

Healthy Volunteers

Australia
Drugs for Neglected Diseases

Completed

ADME Study of Acoziborole in Healthy Subjects

Trypanosomiases, African

United Kingdom
Pfizer

Completed

Study To Characterize Mass Balance, Absolute Bioavailability, Fraction Absorbed And Pharmacokinetics Of 14C PF-06882961

Healthy Volunteer

Netherlands

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