Search clinical trials for: [11C]MK-3168

Total 3936 results

Massachusetts General Hospital
Genentech, Inc.

Unknown

Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation

Multiple Sclerosis
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid (PET)

Alzheimer's Disease

Sweden
National Institute of Allergy and Infectious Diseases...

Completed

Pharmacokinetics of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048

HIV Infections

United States
Peking Union Medical College Hospital

Recruiting

[18F]Florbetazine ([18F]92) for Beta Amyloid PET Imaging in Alzheimer's Disease

Alzheimer's Disease

China
Universitaire Ziekenhuizen KU Leuven
CHDI Foundation, Inc.

Not yet recruiting

Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.

Huntington Disease

Belgium
Christine Elizabeth Edmonds

Withdrawn

Imaging With [11C]Martinostat in Breast Cancer

Breast Cancer

United States
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY

Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Completed

Bioavailability of Variably Aged MK-0974 Tablets (MK-0974-038)(COMPLETED)

Migraine
AstraZeneca

Completed

Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration

Brain Distribution of [11C]AZ12807110 and AZD5213

Sweden
Merck Sharp & Dohme LLC

Completed

Study of MK-2118 Administered as Intratumoral Injection as Monotherapy and in Combination With Pembrolizumab (MK-3475) or by Subcutaneous Injection in Combination With Pembrolizumab in the Treatment of Adults With Advanced/Metastatic Solid Tumors or Lymphomas (MK-2118-001)

Lymphoma | Solid Tumor

United States, Israel
Johns Hopkins University
United States Department of Defense

Not yet recruiting

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

ALS
Hospices Civils de Lyon

Recruiting

Early Diagnosis of Pseudoprogression Using 11C-Methionine PET-MRI After Concomitant Radiochemotherapy Treatment for Glioblastoma. (TIGRE)

Glioblastoma

France
Masaryk Memorial Cancer Institute

Active, not recruiting

11C-methionine in Diagnostics and Management of Glioblastoma Multiforme Patients (GlioMET) (GlioMET)

Glioblastoma Multiforme

Czechia
Chinese University of Hong Kong

Recruiting

A Novel Integrative Non-invasive Embryo Selection Approach for in Vitro Fertilization Based on Artificial Intelligence Enhanced Morphokinetic Analysis and Raman Spectra in Spent Culture Media

IVF | Reproductive Issues | Subfertility

Hong Kong
Merck Sharp & Dohme LLC

Terminated

Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006)

Hepatic Insufficiency | Antibacterial Agents

United States
Merck Sharp & Dohme LLC

Completed

Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002)

Neoplasms | Cancer | Metastatic Solid Tumors | Locally Advanced Tumors
Merck Sharp & Dohme LLC

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of MK-8876 in Participants With Hepatitis C Infection (MK-8876-003)

Hepatitis C
Merck Sharp & Dohme LLC

Terminated

Acute Dosing of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-003)

Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC

Completed

A Pharmacokinetic Study of MK-3102 in Participants With Impaired Hepatic Function (MK-3102-031)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC

Completed

Safety and Pharmacokinetics of MK-7680 in Participants With Hepatitis C (MK-7680-003)

Hepatitis C
Merck Sharp & Dohme LLC

Completed

Phase I Study of MK-1496 in Patients With Advanced Solid Tumor (MK-1496-002 AM 4)(COMPLETED)

Neoplasms | Malignant
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer

Brain and Central Nervous System Tumors

United States
ALK-Abelló A/S
Merck Sharp & Dohme LLC

Completed

A Dose-Ranging Study of the Safety and Effectiveness of MK-8237 in the Treatment of House Dust Mite (HDM) Induced Allergic Rhinitis/Rhinoconjunctivitis in Adults (MK-8237-003/P07627)

Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Nonseasonal
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Parkinson's Disease | Dementia | ALS | Alzheimer's Disease

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Recruiting

AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

Carcinoid Syndrome | Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm

United States
Wuhan Union Hospital, China

Recruiting

The Diagnostic Value of Hybrid PET/MR for Systemic Amyloidosis

PET/MR | Systemic Amyloidosis

China
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Withdrawn

Concurrent PET D2/D3 Receptor Imaging and fMRI Smoking Cue Reactivity in Smokers

Nicotine Dependence | Smoking Cue Reactivity | Relapse to Smoking

United States
Merck Sharp & Dohme LLC

Completed

[18F]MK-6240 Positron Emission Tomography (PET) Tracer First-in-Human Validation Study (MK-6240-001)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Safety and Tolerability of MK-0517 in Healthy Subjects (MK-0517-012)

Postoperative Nausea and Vomiting | Chemotherapy-Induced Nausea and Vomiting
Moon (Guangzhou) Biotechnology Co., Ltd.

Not yet recruiting

Clinical Study of MNC-168 Enteric-coated Capsule in the Treatment of Advanced Intestinal Solid Tumor (MNC-168)

Advanced Malignant Solid Tumors
National Institute of Mental Health (NIMH)
Uniformed Services University of the Health Sciences; Suburban Hospital

Completed

Translocator Protein and Inflammation After Traumatic Brain Injury

Healthy | Traumatic Brain Injury (TBI)

United States
Justin Sims

Terminated

11C-acetate for Treatment Response After Radiotherapy for HCC

Hepatocellular Carcinoma

United States
Yonsei University

Completed

Lower Femtosecond Laser Energy Levels Lead to Better Visual Recovery After Small-incision Lenticule Extraction for Myopia

Myopia

Korea, Republic of
Columbia University

Terminated

Topical Menthol for the Treatment of Chemotherapy Induced Peripheral Neuropathy

Breast Cancer | Colon Cancer | Neuropathy

United States
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Pharmacokinetics & Food Effect of MK-0941 in Adults With Type 2 Diabetes (MK-0941-009)

Type 2 Diabetes Mellitus
Karolinska University Hospital
University of Copenhagen

Completed

Postoperative Neuroinflammation and Cognitive Dysfunction After Abdominal Surgery (POPE)

Surgery | Anesthesia | Neurogenic Inflammation | Cognitive Disorders
UCB Pharma
Yale University; PRA Health Sciences

Completed

A Brain Imaging Study With Positron Emission Tomography and the Radiotracer [11C]UCB-J to Estimate How Fast Brivaracetam and Levetiracetam Enter the Brain in Healthy Volunteers

Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)

Renal Impairment
Tammie L. S. Benzinger, MD, PhD

Enrolling by invitation

Study of Tau Imaging With the Use of [18F]MK-6240 Tracer (MKADAD)

Alzheimer Disease

United States
Merck Sharp & Dohme LLC

Terminated

A Study to Evaluate MK-0482 for Relapsed/Refractory Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML) (MK-0482-002)

Relapsed or Refractory Acute Myeloid Leukemia | Relapsed or Refractory Chronic Myelomonocytic Leukemia

United States, Israel, Spain
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Influence of Hepatic Impairment on MK-8189 Treatment (MK-8189-012)

Hepatic Impairment

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety, Tolerability, and Efficacy of MK-8353 in Participants With Advanced Solid Tumors (MK-8353-001)

Tumor, Solid
Merck Sharp & Dohme LLC

Completed

Evaluation of MK-1075 in Participants With Hepatitis C Virus (HCV) Infection (MK-1075-002)

Hepatitis C
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC

Completed

Study of MK-2206 in Patients With Metastatic Neuroendocrine Tumors (NET)

PANCREAS | Neuroendocrine

United States
Merck Sharp & Dohme LLC

Completed

A Study of Absorption, Metabolism, Excretion and Mass Balance After a Single Dose Administration of MK-0941 (MK-0941-016)(COMPLETED)

Type 2 Diabetes
Merck Sharp & Dohme LLC

Completed

A Two-Part, Single-Dose Study of the Pharmacokinetics of MK-8931 in Subjects With Renal Insufficiency (MK-8931-009 [P08535])

Alzheimer's Disease
Tharick Pascoal
National Institute on Aging (NIA)

Recruiting

Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease (HEAD)

Alzheimer Disease

United States, Canada, Spain
Merck Sharp & Dohme LLC

Recruiting

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008)

Colorectal Cancer

United States, Belgium, Canada, Germany, Italy, Korea, Republic of, Poland, Russian Federation, Spain, Turkey, United Kingdom, France, Denmark, Romania, Estonia, Hungary, Guatemala, Costa Rica, Lithuania, Greece, Colombia, Netherl...
Adam Brickman
National Institute on Aging (NIA)

Completed

Alzheimer's PET Imaging in Racially/Ethnically Diverse Adults

Alzheimer Disease

United States
Repertoire Immune Medicines

Terminated

RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma

Melanoma | Cervical Cancer | Head and Neck Squamous Cell Carcinoma

United States

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